Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
name 3 types of HNPCC
|
1) Lynch I=colon
2) LynchII=CUB=colon, uterus, breast 3) Muir Torre=colon, sebaceous adenoma, others |
|
|
what genetic problem in HNPCC
|
mutation in DNA repair gene results in dinucleotide instability
|
|
|
name types non-neoplastic polyps
|
inflamm (IBD), juvenile (4-6), Peutx Jegher
|
|
|
what genetic mutation of FAP (chrom, gene name, inheritance)
|
chrom 5, mutation in APC gene, AD
|
|
|
besides GI, abd pain in Crohns could be? in UC?
|
cholesterol gallstones, UC think PSC esp when jaundiced, etc
|
|
|
skin manifestation in Crohns
|
erythema nodosum
|
|
|
PBC assoc? PSC assoc?
|
PSC-UC
PBC-female, autoimmune |
|
|
what part GI tract Crohn's usu involve
|
term ileum, SI, colon (rectal sparing)
|
|
|
risks stomach cancer
|
nitrosamines, achlorhydia, chornic gastritis
|
|
|
risk colon cancer
|
villous adenomas, IBD, low fiber, incr age, FAP/HNPCC/FHx
+smoke??? |
|
|
ab in celiac (3)
|
antigliaden, antiendomysial, anti-tissue translutaminase
|
|
|
risks eso cancer
|
EtOH, smoke, barrette's, diverticuli, plummer-vinson, familiar
|
|
|
EtOH a risk for what cancers
|
eso, most H and N, HCC,
|
|
|
risks uterine cancer
|
estrogen, obesity, DM, HTN
|
|
|
risks cervical cancer
|
early sex, multiple sex partners, ?smoking? (assoc HPV 16, 18, 31, 33)
|
