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49 Cards in this Set

  • Front
  • Back
are paramyxoviridae enveloped?
yes
what is the shpae of paramyoviridae?
helically symmetrial nucleocapsid
how many glycoprotein spikes are there on paramyxoviridae?
2
where does replication take place for paramyxovirida?
cytoplasm
Rhinderpest
highly contagious dz
domestic and wild ruminants
characterisitc feature:
high mobidity 90%
high mortality 100%
what are the animal hosts of the Rhinerpest virus?
dz of cattle and domestic buffalo, including water buffalo.
most wild and domestic cloven-footed animals can become infected- zebu, sheep, goats, pigs, and wild ungulates in contact with cattle
what is the transmision of Rhinderpest virus?
Direct- nasal, ocular, feces, urine, saliva, and blood.
Contaminated food or water
indirect-fomites
aerosol- very short distance
can animals be carriers of Rhinderpest?
no
when is the infectious period of rhinderpest and when do clinical signs develop?
infectious period 1-2 days before clinical signs and 8-9 days after the onset of clinical signs
what ar ethe clinical signs of the classic form of rhinerspest?
fever, depression, anorexia
constipation followed by hemorrhagic diarrhea
serous to mucopurulent nasal/ ocular discharge
necrosis and erosion of oral mucosa
enlarged lymph nodes
death in 6-12 days
what are the peracute signs of Rhinderpest
young animals high fever with congested mucous membranes, death in 2-3 days
what are the subacute clinical signs of rhinderpest?
mild clinical signs with low mortalitly
what are the clinical signs of atypical rhinderpest?
irregular fever, mild or no diarrhea
immunosuppression leading to secondary infections
in enemic areas, what is strange?
there could be mild dz.
what are the lesions in the esophagus with Rhinderpest?
brown and necrotic foci
what are the lesions of the omasum in Rhinderpest?
rare erosions and hemorrhage
what are the lesions of the small intestine, abomasum, cecum and colon in Rhinderpest?
necrosis, edema, and congestion, tiger striping
lesions of the lymph nodes in rhinderpest
swollen and edematous
lesions of the gall bladder in rhinderpest
hemorrhagic mucosa
lesions in the lungs in rhinderpest
emphysema, congestion, areas of pnemonia
what are d/d of rhinderpest
infectious bovine rhinotrachetis
bovine viral diarrhea
malignant catarrhal fever
foot and mouth dz
blue tongue
salmonellosis
paratuberculosis
peste des petits ruminants
diagnosis of rhinderpest
clinical and path. lesion
rapidly spreading acute febrile illness in all ages of animals
accompanying signs of RPV
what are the lab tests to do for RPV
isolation and confirmation of virus
cytopathic effects in cell cultures confirmed by immunofloresence
what are the samples to collect for virus isolation for live animals for RPV?
viremia drops when fever falls and d+ begins
blood sample-white cells from buffy coat
swabs of lacrimal fluid
necrotic tissue of oral cavity
aspirations of superficial lymph nodes
what are the samples to collect from dead animals for RPV?
spleen, lymphy node, tonsil
what kind of tests can be used to diagnose RPV?
AGID or counter immunoelctrophoresis
RT-PCR: D/D Peste des petits
competitive ELISA
PM enteric lesions-zebra stripe
what can control the RPV?
chemical-gylcerol and lipid solvents.
natural- pH 2 and 12 for at least 10 min.
what is the optimal pH for virus survival?
ph 6.5- 7
what kind of vaccine can be used for RPV?
cell-culture-adapted
What is the purpose of Law of Armed Conflict (LOAC)?
A broad base set of rules defining how war is fought. the rules are generalized rather than extremely specific, and are designed to apply to any armed conflict. Their purpose is to prevent unnecessary loss of lives or destruction of property on the battlefield.
how do you vaccinate endemic areas for RPV?
vaccinate national herd according to recommendations
how do you vax. high-risk countries?
vaccination of susceptible animals
how do you vax. RPV free countries?
import restrictions on susceptible animals and uncooked meet products from infected countries
how can RPV become eradicated?
vax available including long lasting immunity
reliable diag. tests
absense of carrier animals
absence of wild life reservoirs
animal movement restricted
what is the single most important measure to prevent disease transmission of RPV?
control of animal movement
how do you vaccinate endemic areas for RPV?
vaccinate national herd according to recommendations
how do you vax. high-risk countries?
vaccination of susceptible animals
how do you vax. RPV free countries?
import restrictions on susceptible animals and uncooked meet products from infected countries
how can RPV become eradicated?
vax available including long lasting immunity
reliable diag. tests
absense of carrier animals
absence of wild life reservoirs
animal movement restricted
what is the single most important measure to prevent disease transmission of RPV?
control of animal movement
Peste des petitis ruminants (PPR)
severe dz of small ruminants, particularly in sheep and goats
resembles RPV
high morbidity
high mortality
what is the family and genus of PPRV?
family- paramyxoviridae
genus- morbillivirus
where does PPRV occur?
sub-saharan Africa, the middle east, India, and Pakistan
what type of "list dz" is PPRV?
list A dz
is PRRV more or less severe in goats?
more severe
who are the animal host of PRRV?
principally goats and sheep
one report of captive wild ungulates
american white-tail deer
cattle and pigs serocovert but do not transmit dz
high morality in indian buffalo
what is percentage of morbitiy of PRRV?
80-90%
what is the percentage of mortality of PRRV?
50-80% (can be up to 100%)
who is PRRV more severe in?
young animals, poor nutrition, concurrent parasitic infecitons.goats more susceptible than sheep.