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16 Cards in this Set

  • Front
  • Back
Describe the functions of the nervous system
Communication
1. Between periphery of body and brain
- provides information (SENSORY)
- e.g. pain, pressure, temperature, touch, conscious proprioception
2. Between brain and periphery of body provides: (MOTOR)
- Voluntary control of effectors (skeletal muscles) in the periphery = somatic
- Involuntary control of effectors (smooth muscle, cardiac muscle, glands) in periphery = autonomic
What makes up the somatic nervous system?
- 31 pairs of spinal nerves (spinal segments)
• 8 cervical
• 12 thoracic
• 5 lumber
• ~ 5 sacral
• 1+ coccygeal
- 12 pairs of cranial nerves
Describe a basic scheme of the nervous system
- Somatic and visceral systems are largely the same
- However, visceral systems are fed by autonomic nerves and therefore the visceral motor is made up of 2 nerves fibres rather than one, and an extra synapse
Describe the formation of spinal nerves
- The dorsal root contains only sensory fibres, which synapse at the dorsal root ganglion
- The ventral root contains only motor fibres
- The two roots come together to form a mixed spinal nerve
- Spinal nerve gives off a mixed dorsal ramus and a mixed ventral ramus
Label this diagram:
What is the lateral horn?
- Found between the ventral and dorsal horns of grey matter
- Found only at levels T1-L2 and S1-S4 = autonomic
Describe the basic pathophysiology of polio
- Infection attacks only the cells of the anterior horn
- This means that there are no motor signals to smooth muscle, causing paralysis and muscle wastage
Describe the pathophysiology of saryngomyelia
- Cleaved dorsal horn → no sensory input
- Means that keep burning themselves etc as no feeling
Describe the morphology of grey matter
- Different shapes at each anatomical segmental level
- Note the large anterior horns for the cervical and lumbar plexi i.e. the arms and legs
Describe the topographical anatomy of the spinal cord
- True spinal cord ends at L1/L2 in the adult (and L3/L4 in the child)
- The dura and arachnoid mater i.e. the foetal sac end at S2
Describe the spinal meninges
- Dura mater is a thick fibrous sheath surrounding the spinal cord and the spinal nerves and their rami
- Arachnoid mater is a thin, web-like layer that also covers the spinal nerves and rami
- Pia mater closely adheres to the tissue of the spinal cord and forms denticulate ligaments, which anchors the cord to the arachnoid and dura maters
Describe the arterial supply to the vertebral column
- Anterior spinal artery formed by the union of vertebral arteries run from the medulla of the brainstem to the medullary cone of the spinal cord
- 2 posterior spinal arteries are branches of either the vertebral artery of the posteroinferior cerebellar artery
- Also anterior and posterior segmental branches which are derived from spinal branches of:
• ascending cervical
• deep cervical
• vertebral
• posterior intercostal
• lumbar arteries
- Most of these are branches from the aorta
Describe the venous drainage of the spinal column
- 3 Anterior and 3 posterior spinal veins form internal (anterior and posterior) venous plexi. Note that these veins (in the epidural space) are valveless
- Also external (anterior and posterior) venous plexi
- Basivertebral and intervertebral veins are involved in marrow drainage
What is a nerve plexus?
- Peripheral nerves that divide and join other nerves to weave a network
- Plexus permits individual nerve fibres to pass from one peripheral nerve to another, allowing redistribution of nerve roots
- The only parts of the body that are not covered by plexi are T1 to L2 segmental innervation of skin and muscles
Describe the pathophysiology of Herpes zoster
- If Herpes zoster is caught it is never fully removed from the body but can remain latent in nerve cell bodies
- They can remain there for many years without causing symptoms
- Years or decades after a chickenpox infection, the virus may break out of nerve cell bodies and travel down nerve axons to cause viral infection of the skin in the region of the nerve.
- The virus may spread from one or more ganglia along nerves of an affected segment and infect the corresponding dermatome causing a painful rash.
Describe the 3 classifications of nerve injury
1. Neuropraxia = 1st degree
- No axon degeneration
- Rapid recovery
2. Axonotmesis
- Wallerian degeneration
- Endoneurium survives = weakness and tingling due to damage and degeneration
- Nerve fibre will eventually grow back down Schwann cell tube unless the tube is cut and feeling will be restored
3. Neurotmesis = 5th degree
- Division of a trunk = nerve ends detatched