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33 Cards in this Set

  • Front
  • Back

Three important species of Yersinia?

1. Y. enterocolitica


2. Y. pseudotuberculosis


3. Y. pestis

Y. enterocolitica

inflammation to the intestinal tract

Y. pseudotuberculosis

resembles TB, but caused inflammation in the intestinal tract. Bacteria get trapped in the diverticuli region of the large intestine and resembles chronic inflammation (tubercles) of TB

Y. pestis

causes bubonic and pneumonic plague. Transmitted from rodents (either direct contact or from fleas) not transmitted through fecal oral route. After the transmission it travels to lymph nodes and forms inflammation, buboes (inflamed lymph nodes)

bacteremia

bacteria enter the blood

septicemia

bacteria enter the blood and multiply

cholera

Vibrio cholarae curved rod shaped bacteria that produces cholera toxin that leads to fluid loss. Cholera is waterborne but the infection can be acquired by contaminated food as well

Vibriosis

Vibrio parahaemolyticus, common in Japan due to consumption of raw fish

Travelers diarrhea

pathogenic strain of E. coli

Enterohemorrhagic colitis

E. coli O157:H7


O-refers to a LPS endotoxin antigen number


H (from German work Hausch)-refers to a flagella antigen

Peptic ulcers and chronic gastritis

Helicobacter pylori. This bacteria is able to survive acidic conditions of the stomach and invade the stomach lining (gastric mucosa) Ulcers were known to be caused by stress until a scientist drank the bacteria to prove that ulcers were caused by H. pylori. Pyloric sphincter, region in the stomach is more susceptible to H. pylori hence the name pylori. H. pylori triggers cofactors that lead to ulcers and mechanisms that will prevent normal immune response which was linked to stomach cancers.

CDAD

Clostridium difficle, transmission by touching surfaces or health care employees. Symptoms include diarrhea, necrosis of the skin, colitis, inflammation, abdominal camps, abscess of intestinal lining, weight loss, and loss of appetite. Tests include endoscopy and observed for Peyer's patches; they present in healthy individuals if infected Peyer's patches are wiped off. Stool specimens are also tested. C. diff produces toxins

Hepatitis

inflammation of liver, usually caused by a virus but amoeba can be causative agent as well

Different types of Hepatitis:

Hep A-is caused by a Hepatitis A virus (single stranded RNA virus)


Hep B-caused by the Hepatitis B virus (ds DNA virus) transmission is via blood


Hep C-diagnosed in the absence of HAV or HBV


Hep D-the mos severe form of hepatitis, is caused in the presence of HBV and HDV


Hep E-transmitted by fecal oral route

Viral enteritis

Rotavirus


transmitted by fecal oral route, more common in infants

Platyhelminths:

Flukes-Fasciola hepatica


Tapeworms- Taenia soleum. They are able to reproduce sexually and asexually and are able to regenerate

Nematodes:

Trichonosis- Trichinella spiralis


Hookworms- Necator americanus


Ascariasis-Ascaris lumbricoides

Lancefield grouping

method of grouping B-hemolytic bacteria based on their carbohydrate composition of bacterial antigens

Group A

Strep pyogenese, beta hemolysis, bacitracin sensitive

Group B

Strep agalactae, without milk, beta hemolytic bacitracin R

Group C

gamma hemolysis (no hemoysis), bacitracin R

Group D

Strep pneumo and Strep viridans, alpha hemolysis (partial, looks green, hence the viridans name)

Septic shock

life-threatening; low blood pressure, collapse of blood vessels. Typically caused by Gram negatives due to endotoxin

Anthrax

causative agent is Bacillus anthracis, virulence factors endotoxins and endospore production

3 Types of Anthrax

A.Cutaneous-escar


B.Respiratory-inhalation of endospores


C.Intestinal-ingestion of bacteria or the endospore

plague

systemic, causative agent is Y. pestis, found in pork

Francisella tularenis

zoonosis found in more than 100 mammals-especially cottontail rabbits, muskrats, and rodents and arthropod vectors such as ticks and deer flies

Level A Bioterroism agents

Anthrax


Smallpox


Plague


Botulism Toxin


Tularemia


Viral Hemorrhagic Fevers

Anthrax

Bacillus anthracis (bacteria)

Smallpox

Variola major (virus)

Plague

Yersinia pestis (bacteria)

Botulism toxin

C. botulinum (bacteria)

Tularemia

Francisella tularensis (bacteria)