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36 Cards in this Set
- Front
- Back
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SSRI Drugs: - Names? |
1. Fluoxetine (Prozac) 2. Sertaline (Zoloft) 3. Paroxetine (Paxil) 4. Fluvoxamine (Luvox) 5. Citalopram (Celexa) 6. Escitalopram (Lexapro) |
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SSRI side effects? |
- Akathesia - Sexual dysfunction - Serotonin syndrome (restlessness, hyperthermia, confusion, muscle ridigidty) - HA - Nausea - Bruxism - Diaphoresis - Irritability - Anxiety |
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SSRI Black box warning? |
Suicide if < 24 years old |
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SSRI during pregnancy? |
May stunt baby growth |
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Citalopram: - Class? - SE? |
SSRI; SE: - SSRI SE - can prolong QTc when > 40 mg - Least drug interactions though |
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What drug is used for social anxiety? |
SSRI; Escitalopram (Lexapro) |
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Fluoxetine: - Drug class? - Side effects? |
Prozac; SSRI Some risk of pulmonary HTN in pregnancy. Extended release, so not as many SE when you stop taking abruptly. |
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What drug is used for OCD? |
SSRI Fluvoxamine (Luvox) |
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Paroxetine: - Drug class? - Side effects? - Good for what? |
SSRI SE: High anticholerginic properties. Cat D in pregnancy!**** Good for premature ejactulation |
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What is the best SSRI for breastfeeding? |
Sertraline (Zoloft) |
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SNRI: - Drugs? |
1. Desvenlafaxine (Pristiq) 2. Duloxetine (Cymbalta) 3. Levomilnacipram (Fetzima) 4. Venlafaxine (Effexor) |
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SNRI drug: - Side effects? |
- With abrupt stopping, you can get flu-like symptoms - SE same as SSRI - Higher risk of HTN with SNRI's |
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What antidepressant medication is also indicated for general pain? |
SNRI Duloxetine (Cymbalta) |
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What medication has a higher risk of HTN? |
SNRI Venlafaxine (effexor) |
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What medication can you use for women going through menopause? |
SNRI Venlafaxine (effexor) |
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Atypical antidepressants: - Names? |
1. Buproprion (wellbutrin) 2. Maprotiline 3. Mirtazapine (Remeron) 4. Nefazodone (Serzone) 5. Trazodone (Oleptro) 6. Vilazodone (Viibryd) |
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What medication helps sleep in alcohol dependence and is also used for anxiety? |
Gabapentin (Neurotin) |
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What is Topiramate used for? |
Topamax; used for mood stability, cocaine dependence, alcohol dependence |
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Buproprion: - MOA? - Used for what? - SE? - CI? |
Wellbutrin MOA: blocks reuptake of dopamine and norepinephrine. Use: smoking cessation; anxiety without depression; lethargy; poor focus; poor energy No sexual side effects; activating medication so not good for insomnia CI: seizures or eating disorders Can use with SSRI or SNRI |
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What is the only antidepressant with category B? |
Maprotiline, an atypical |
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Mirtazapine: - MOA? - Used for what? - SE? |
MOA: Central alpha2 antagonist, leading to increased available norepinephrine and serotonin Used as anti-nausea and anti-histamine and anti-depressant SE: weight gain, dry mouth, morning fatigue |
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Nefaxodone : - Use? - SE? |
Atypical antidepressant Sedating. Can cause liver damage so monitor enzymes. |
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Trazodone: - Use? - SE? |
Atypical antidepressant and used for sleep; lower doses used for sleep and higher doses used for depression SE: Priaprism, sedation, dry mouth, sedation in the morning |
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TCA Antidepressants: - Names? |
1. Amitriptyline 2. Amoxapine 3. Clomipramine (Anafranil) 4. Desipramine (Norpramin) 5. Doxepin 6. Imipramine (Tofranil) 7. Nortriptyline (Pamelor) 8. Protriptyline (Vivacil) 9. Trimipramine (Surmontil) |
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TCA SE? |
COSAS: Constipation, orthostasis, sedation, anticholergenic, seizure threshold lower, + other serotonin SE's Can prolong QTc and lead to tornadoes Get EKG if > 65 years old before treating Can die from overdose |
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What medication if used off label for migraines and sleep? |
Amitriptyline |
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What antidepressant has a higher risk of tradeoff dyskinesia? |
Amoxapine |
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What TCA antidepressant is the drug of choice for OCD? |
Clomipramine (Anafranil) |
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MAOI Antidepressants: - Drugs? |
1. Isocarboxazid (Marplan) 2. Phenelzine (Nardil) 3. Selegilne transdermal (Emsam) 4. Tranylcypromine (Parnate) |
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MAOI: - MOA? - SE? - Be careful of what? |
- MOst efective form of antidepressant - MOA: blocks breakdown of catecholamines - Diet: avoid tyramine, could get HTN crisis Washout period of all medications: - Stop fluoxetine for 6 weeks before starting MAOI - For all other SSRI, wait 2 weeks - Same is true for dopamine agents, don't use Tramadol, methadone, fentanyl; be careful with contraindicated medications, you could kill someone! - Don't use trepans!!! |
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What atypical antidepressant lowers seizure threshold? |
Burproprion (wellbutrin) |
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What atypical antidepressant s stimulating and increases DBP? |
Venlafaxine (effexor) |
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What atypical antidepressant has less sexual side effects but can cause weight gain and increased appetite? |
Mirtazapine |
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What atypical antidepressant can treat insomnia but has SE of sedation and priaprism? |
Nefazodone/Trazodone |
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What atypical antidepressant should you avoid in patients with renal failure? |
Duloxetine (cymbalta) |
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What antidepressant can treat neuropathic pain? |
Duloxetine (cymbalta) SNRI |
