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16 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What is the four processes of pharmacokinetics |
Absorption, distribution, metabolism, excretion |
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define absorption |
Movement of drug in blood stream |
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what factors affect absorption |
Route of administration, drug solubility, pH / ionization , blood flow |
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Define distribution |
Drug transport to tissues and organs |
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What factors affect distribution |
Local blood flow, membrane permeability, protein binding capacity |
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What is metabolism of medication |
Biotransformation |
Chemical conversion of drug |
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What is the rule of thumb for medication |
Lowest effective dose for shortest period time |
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Why do children get higher doses of medication |
Fast metabolisms... Need higher dose to remain therapeutic |
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Why do 55 year olds and older receive lower doses |
Higher risk of toxic reaction |
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what is the major organ of elimination |
The kidney |
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What is the major organ of metabolism |
The liver |
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The liver changes drugs from _____ soluble to _____ soluble so kidney can excrete |
Fat, water |
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What kind of drug interactions are there |
Antagonistic, synergistic, incompatibilities |
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What are the 6 rights of medication |
Right dose, route , medication, time, patient, documentation |
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What are the other medication |
Right reason, right to know, right to refuse |
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What is the first thing you do if there is a medication error |
Immediately assess vital signs and physical status |
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