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16 Cards in this Set

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What is the four processes of pharmacokinetics

Absorption, distribution, metabolism, excretion

define absorption

Movement of drug in blood stream

what factors affect absorption

Route of administration, drug solubility, pH / ionization , blood flow

Define distribution

Drug transport to tissues and organs

What factors affect distribution

Local blood flow, membrane permeability, protein binding capacity

What is metabolism of medication

Biotransformation

Chemical conversion of drug

What is the rule of thumb for medication

Lowest effective dose for shortest period time

Why do children get higher doses of medication

Fast metabolisms... Need higher dose to remain therapeutic

Why do 55 year olds and older receive lower doses

Higher risk of toxic reaction

what is the major organ of elimination

The kidney

What is the major organ of metabolism

The liver

The liver changes drugs from _____ soluble to _____ soluble so kidney can excrete

Fat, water

What kind of drug interactions are there

Antagonistic, synergistic, incompatibilities

What are the 6 rights of medication

Right dose, route , medication, time, patient, documentation

What are the other medication

Right reason, right to know, right to refuse

What is the first thing you do if there is a medication error

Immediately assess vital signs and physical status