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16 Cards in this Set
- Front
- Back
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The _______ immune response is controlled by antibody, while the ___________ immune response is controlled by T-cells and macrophages
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humoral; cellular
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Immunoglobin is made of _________ heavy chains and __________ light chains
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2 identical; 2 identical
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What are the products of papain Ig cleavage?
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two Fab (fragment antigen binding) and one Fc (fragment crystallizable)
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What are the five major antibody classes?
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IgG, M, A, D and E
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which Ig is the primary type to induce anaphylaxis?
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IgE
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What are the two major light chain isotypes?
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kappa and lambda
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antigen binds at the ___-termini of antibody
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N
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Which Ig's are capable of transport across the placenta?
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IgG (IgG1 in particular)
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Which Ig is best at transport across the epithelium?
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IgA dimer
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Which Ig is best at opsonization?
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IgG1
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Hypervariable regions on antibody are found on the ___-termini
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N
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what is the primary Ig on mucosal membranes?
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IgA
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Dermititis Herpetiformis is an example of what type of antibody?
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auto-reactive
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Ig__ is found at highest serum levels in primary response. Ig___ and Ig__ are found at highest levels in secondary response
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M; G; A
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Which laboratory test is used to confirm HIV antibodies?
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Western Blot
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A patient with chronic bacterial sinus infection should be suspected of what type of immunodeficiency?
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selective IgA immunodeficiency
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