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9 Cards in this Set

  • Front
  • Back

What species of parasite is malaria caused by

Plasmodium species



P vivax -65 percent of cases


P falciparum - more virulent


P Knowlesi - emerging in Europe and Asia

What is the vector of malaria

Anopheles mosquito

What animals can malaria infect

Reptiles birds mammals

Is malaria intracellular or extracellular

Intracellular within RBCs

What are symptoms of malaria

Fever, fatigue, nausea, vomiting, coma, death

What type of malaria can lead to cerebral malaria and why

P falciparum


Causes sequestration of infected RBCs and can lead to ruptured of the blood brain barrier resulting in haemorrhage and neurological alterations



They bund to PECAM1 AND ICAM1

What is the drug treatment for malaria

Quinine


Artenisinin based combination therapy ACT


primaquine

What's the name of the malaria vaccine

RTS,S or mosquirix


R21 - more effective, new, only provided in Ghana and Nigeria

What does p vivax use to enter into rbcs

The Duffy antigen