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5 Cards in this Set
- Front
- Back
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What are macrolides?
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Macrolides slows the growth of micro-organisms by inhibiting protein synthesis
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What are some examples of macrolide drugs?
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-Erytrhomycin (E-Mycin)
-Azithromycin (Zithromax) |
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What are macrolide drugs used to treat?
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-Useful in clients who have a penicillin allergy, such as prophylaxis against rheumatic fever and bacterial endocarditis
-Whooping cough (pertussi) -Acute diphtheria -Chlamydia infections -Upper respiratory tract infections |
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What are some possible adverse reactions that may occur with macrolides?
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-GI discomfort (nausea, vomiting, epigastric pain - clients can administer eryhromycin with meals if GI upset occurs)
-Hepatoxicity (abdominal pain, lethargy, jaundice) -Prolonged QT interval causing dysrhythmias and possible sudden cardiac death - clients who have dysrhythmias) -Clients who have a pre-existing liver disease should avoid taking erythromycin (macrolides) |
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Are macrolides administered on an empty stomach?
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Yes, 1 hour before or 2 hours after with a full glass of water, unless GI upset occurs
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