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13 Cards in this Set

  • Front
  • Back

Body has virus how does natural defense react

Ifn a and b produced by infected cell


And Direct killing by NK cells

The infected virus cell produce what in response as a natural defense

INF a and b

These mechanisms are important In the very early course of viral infections before immune responds. Directly kills virus infected cells

NK cells

How does the immune respond to viruses ?

Combo two mechanisms humoral and cell mediated

Viruses humoral response

Specific antibody basis for immunity in early infection in resp and gi related viruses IgA secretory immunity

What is positive importance of early humoral immune response early in the virus infection

Provides long lasting protection after infection has cleared

Virus associated humoral immunity a target for what kind of vaccines

Oral

How can virus humoral immune response damage tissue?

Circulating immune complexes ag-an may lodge in blood vessels and initiate c mediated tissue damage

What is the principle mechanism for combating established viral infections

Cytotoxic t lymphocytes

What do Tc cells do to curb viral infections

Directly kill virus infected cells once virus has been established

May be responsible for tissue injury in non cytopathic virus infections

Tc cells

Evasion of immune response most obvious mechanism

Intracellular persistence

Some mechanisms that viruses use to evade host defenses

Antigen variation


Direct suppression of immune response