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23 Cards in this Set

  • Front
  • Back

Risk factors for ICH

Hypertension


cerebral amyloid angiopathy


cocaine use


low cholesterol


oral anticoagulant use


excessive ETOH abuse

What is the significance of an irregularly shaped ICH?

Greater hematoma growth, probably indicates that bleeding occurred from multiple arterioles

Dose of FFP for warfarin reversal

15 mL/Kg, usually 4-6 units (200mL) each)

What is the dose of protamine sulfate for UFH and LMWH reversal?

1mg per 100 units of heparin


1mg per 1mg of enoxaparin

What is the dose of DDAVP for platelet dysfunction?

0.3 ug/Kg

FAST Trial recommendations?

Routine rFVIIa fro ICH within 4 hours time window cannot be recommended

Preferred induction agents for RSI in neuro patients

Propofol and etomidate


*short-acting and do not obscure neuro examination for prolonged period of time

Precautions in the use of succinylcholine

Avoid in renal disease - can cause life-threatening hyperkalemia


Causes theoretical ICP elevation in patients with intracranial mass lesions

Preferred neuromuscular blocking agents in neuro patients

Cis-atracurium (esp in renal patients)


Rocuronium


Vecronium

Results of INTERACT trial

Early intensive BP reduction attenuated hematoma expansion in patients with ICH

When should you consider EVD insertion in patients with ICH?

GCS 8 or less


Signs of acute HCP or intracranial mass effect on CT


Prognosis that warrants ICU care

MOA of labetalol?

Alpha1, beta1, beta2 receptor blocker

MOA of labetalol?

Alpha1, beta1, beta2 receptor blocker

MOA of esmolol

B1 antagonist

MOA of fenoldepam

Dopamine 1 receptor agonist

Precautions when using labetalol and esmolol

bradycardia


CHF


Bronchospasm

How to dose 23.4% saline solution?

0.5 to 2.0 mL/Kg

How to dose 23.4% saline solution?

0.5 to 2.0 mL/Kg

Results of the STICH study?

1000 ICH patients, emergent evacuation within 72 hours vs initial medical management - surgery does not improve outcome (except for the subgroup with superficial hematomas and no IVH)

This type of ICH may benefit from emergent surgical evacuation

Cerebellar hemorrhage >3cm diameter

Clear trial tPA protocol

1mg tPA q8h (EVD claimed x 1 hour) until clearance of blood from III ventricle

Clear trial tPA protocol

1mg tPA q8h (EVD claimed x 1 hour) until clearance of blood from III ventricle

When can anticoagulation be restarted in patients with ICH?

In patients with strong indications (mech heart valve, AF with h/o embolic stroke), anticoagulation can be safely implemented after 10 days.