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20 Cards in this Set
- Front
- Back
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232. E. Coli virulence factors?
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a. Fimbriae- Cystitis and pyelonephritis.
b. K capsule- Pneumonia, neonatal meningitis. c. LPS endotoxin- septic shock. |
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233. 4 E. coli strains?
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a. EIEC
b. ETEC c. EPEC d. EHEC. |
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234. EIEC E. coli toxin?
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a. “I” Invasive; dysentery.
b. Produces shiga-like toxin. c. Microbe invades intestinal mucosa and toxin causes necrosis and inflammation |
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235. ETEC Strain?
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a. “T” Traveler’s diarrhoea (water).
b. Labile toxin/stable toxin. No inflammation of invasion. |
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236. EPEC strain?
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a. “P” Pediatrics- Diarrhoea usually in children.
b. No toxin produced. c. Adheres to apical surface, flattens villi, prevents absorption. |
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237. EHEC strain?!?!?
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a. O1571:H7 is the most common serotype.
b. Produces Shiga-like toxin and “H” Haemolytic-uraemic syndrome (triad of anaemia, thrombocytopenia, and acute renal failure). c. Endothelium swells and narrows lumen, leading to mechanical haemolysis and reduced renal blood flow. d. Damaged endothelium consumes platelets. |
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238. Presentation of EHEC O1571:H7 strain infection?
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a. Dysentery (toxin alone causes necrosis and inflammation.
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239. What distinguishes EHEC O1571:H7 strain from other strains of E. coli in culture?!?
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a. Does not ferment sorbitol.
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240. Klebsiella?
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a. Intestinal flora that causes lobar pneumonia in alcoholics and diabetics when aspirated.
b. Red current jelly sputum. c. Also cause of nosocomial UTIs. |
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241. 4 A’s of Klebsiella?
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1. Aspiration pneumonia
2. Abscess in lungs 3. Alcoholics 4. di-A-betics. |
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242. Similarities between Salmonella and shigella?
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a. Both are non-lactose Fermenters
b. Both invade intestinal mucosa and can cause blood diarrhoea. |
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243. Salmonella vs. shigella?
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a. SALMONella (swim) have flagella and can disseminate haematogenously.
b. Only salmonella produce H2S. c. Symptoms of salmonellosis may be prolonged with antibiotic treatments, and there is typically a monocytic response. d. Salmonella have animals reservoir (except S. typhi). |
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244. Do shigella have flagella?
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a. No but can propel themselves while within the cells by actin polymerization.
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245. Virulence of Shigella vs. salmonella?
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a. Shigella is more virulence (10^1 organisms) than salmonella (10^5).
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246. Salmonella typhi symptoms?
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a. Typhoid fever:
1. Fever 2. Diarrhoea 3. HA 4. Rose spots on abdomen. b. Can remain in gallbladder chronically. |
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247. Campylobacter jejuni?
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a. Major cause of blood diarrhoea, esp in children.
b. Fecal-oral transmission through foods such as poultry, meat, Unpasteurized milk |
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248. Campylobacter jejuni characteristics?
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a. Comma or S-shaped
b. Oxidase positive. c. Grows at 42 C “CAMPylobacter like the hot CAMP-fire. |
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249. To what condition is Campylobacter jejuni a common antecedent?
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a. Guillain-Barre syndrome.
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250. Vibrio cholerae Toxin pathophys?
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a. Activates Gs, Increases cAMP.
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251. Vibrio cholerae characteristics?
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a. Comma shaped, oxidase positive.
b. Grows in alkaline media. |
