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5 Cards in this Set

  • Front
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Introduction

-1.2 million people in US are HIV positive


-1 out of 8 don't know they are positive


-In 2015, there was around 39-40 thousand new drug cases/ diagnosis


- from 2005-2014, new dx. decreased by 19%


-55% of people who are positive are virally suppressed


-HIV: human immunodeficiency virus


OM( opportunistic malignant)'s are usually herpes


OI (opportunistic infection)'s are Kaposis Sacorma (cancerous skin blotches)


*what kills people


-virus only replicates w/ host....CD4


-when host cells have taken over-HIV


-minorities tend to be at high risk


- leading cause of death for 35--44 yrs. olds and in black communities


Stigmas- LGBTQ+ population


IV use


Women(mostly in heterosexual relationships) and the elderly are at risk


African Americans represent 12% of the population but 45% of them have it

Statistics

-NC is #6 in the nation for HIV/AIDS dx. and #21 in HIV related deaths


-60% of patients are age 13-34


-our body can cure flu but but not HIV/AIDS


-HIV can hide out in your system


-T cells now called CD4 fight infections


-a healthy CD4 count is 500, anything below 200 means you have AIDS

Treatment

A.R.T.--active trivial therapy helps to keep the HIV virus count low


-should be offered to people who have a risk of spreading HIV during sexual activity


-have to comply w/ ART regime


-skipping doses will help develop new strains that is resistant to that medication


-when first diagnosed w/ HIV, it is called "a wild type" because no identification of the strand and you haven't had any medication


Comprehensive tx. goals-1) living sober 2) harm reduction 3) reduction of risk taking behaviors, slowing progression of virus


* what kills people is not HIV but it is heart disease


Barriers to:


-unstable housing


-food insecurity


-no transportation


-complexity of the system


-getting care for other illnesses


1) HIV infectious disease transmission


a)people started seeing Kaposis Sacorma in 1981 (discoloration of skin associated w/disease)


2) Transmission of HIV


a)transmitted within cells and body fluids


b) blood/blood products


c) semen/pre- seminal fluid


d) rectal fluids


e) vaginal cervical secretions


f) breast milk( vertical transmission)


g) it can't live in water or exposed to oxygen


h) mostly spread thru sex and I've drug use


3) female exposure tend to be higher


* test for HIV developed in 1985

Stages of HIV infection

1. Primary Acute Infection- first time you are exposed...last for several months. Often when people feel flulike...viral load increases fast. Your body can produce viral set points. Cd4 count increases at first but decreases w/ medication...risk for transmission is high


2. Chronic Asymptomatic HIV ( Clinical Latency)- between 3-6 months and your system stabilizes. Virus develops w/o symptoms if any they are mild


3. Severe Immune Compromise/AIDS- succumb to OI/OM'S, if stags 2 is left untreated there is about 2 years to stage 3


- if you have OI/OM you likely have a year to live


*A.R.T can increase lifespan


Factors to progression: age (20-35), expedient diagnosis/treatment, nutrition

OI/OM's

-lymphoma (OM)


-herpes simplex(cold sores)


-thrust (yeast infection)


-cervical cancer


-pneumonia


-hepatitis


-cardovascular disease


-diabetes


-kidney disease


-dementia


*systematic disease


To reduce the risk:


-engage in less risky exposure


-limit your sexual partners


-use condomns every time and correctly


-use prep


-6% of infection came from iv use


-alcohol and drug use increase the risk


-alcohol can worsen the effects of HIV (lowers inhibitions)


-cocaine (crack), methamphetamine, club drugs (estacy)GHB, and dextro. contribute


-people w/ HIV tend to smoke more than general population