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5 Cards in this Set
- Front
- Back
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Retroviruses |
Viruses that use RNA as genetic material Use reverse transcriptase to convert RNA into DNA and integrase to insert its DNA into ours |
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Viral Infection Cycle into Cell |
1. Attachment 2. Fusion 3. Reverse transcription 4. Replication 5. Integration 6. Transcription 7. Translation 8. Migration and assembly 9. Budding off 10. Processing by protease |
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Human Immunodeficiency Virus (HIV) |
Promotes immunodeficiency by killing CD4 T lymphocytes CD4 cells are helper T-cells that trigger the immune response by stimulating other immune cells (B cells and T cells) to fight infection |
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Phases of HIV Infection |
1. Acute Infection—may cause Acute HIV Syndrome because of systemic inflammatory response; CD4 cells are destroyed at a rapid rate until antibodies are mobilized against them 2. Latency Infection—no clinical signs; at the start CD4 levels are higher than viral levels but eventually being to level off; lasts 10 years without treatment 3. AIDS—overwhelming stage may occur beforehand (return of symptoms with weight loss); criteria for defining AIDS is CD4 count less than 200 cells/mL and one AIDS-defining illness |
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Consequences of AIDS |
People with AIDS have a non-functional immune system They die of opportunistic infections |
