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15 Cards in this Set
- Front
- Back
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Three classifications of anemia
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1. increased destruction of RBCs
2. decreased production 3. decreased lifespan in cirulation |
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-HOw much iron can be taken in with a big steak meal with spnach?
-At what rate do we lose iron? -Maximum compensation for loss of iron or lack of absorption? |
~1 mg
~1 mg / month ~4 mg |
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#1 cause of pediatric overload:
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Iron overload
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Drugs like barbituates and anticonvulsants may result in Microcytosis, this is due to:
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Iron deficiency due to decreased absorption
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Iron must be in the _________ state for maximum absorption. It is taken up by _________ transporters to the reticuloendothelial system, then to the bone marrow for hem synthesis
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Ferritin
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Total iron binding capacity TIBC is (increased/decreased) during Iron deficiency anemia
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Increased
Because there are many empty iron transporters due to low iron levels |
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-total iron levels in blood can be elevated, normal, or decreased in this deficiency
-increased ferritin levels -decreased TIBC |
Anemia of inflammation (lack of use)
-blood flow goes to the area of inflammation and sequesters the iron bound to Hb so it can't be used elsewhere |
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Folic acid and B12 is required for the synthesis of what Nucleic acid?
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Thymine
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Bacterial overgrowth and some medications can cause decreased absorption of this vitamin
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B12
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-How long for a vegan to develope B12 deficiency?
-How long until a folic acid deficiency? |
B12 - 5-10 years
Folic acid - 3 months |
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GI issues and celiac sprue (gluten-sensitive enteropathy) can cause this deficiency:
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Folic acid deficiency
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Treatment of Iron in patient with intrinsic factor deficiency:
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Intra venous
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Only homocysteine (methylmalonic acid normal) levels are elevated in this deficiency:
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Folic acid deficient
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Both homocysteine and methylmalonic acid are elevated in this deficiency:
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B12 deficient
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Treatment for B12 and folic acid deficiency:
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200 mg oral supplement
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