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22 Cards in this Set
- Front
- Back
CIs to HRT |
Hormone dependent cancer e.g. breast, thromoboembolic disease e.g. Afib, Liver disease where LFTs have failed to return to normal |
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Indications for HRT |
Early menopause ( prescribe until 51) Hysterectomy before menopause if ovaries are conserved second line treatment of osteoporosis |
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SE of oestrogen |
Fluid retention, breast enlargement and tenderness, nausea and headaches |
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SEs of progesterone |
Headache, weight gain, bloating, depression |
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Risks of HRT |
Breast ca, DVT, Stroke, Gallbladder disease, Ovarian Ca (if oestrogen only preparation) |
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Short term benefits of HRT |
Alleviation of Menopausal symptoms e.g Flushes, sweats, vaginal dryness reduced incidence of UTIs |
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Long term benefits of HRT |
decreased risk of osteoporosis and Colorectal Ca |
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Diagnosis of bacterial Vaginosis |
Grey/white offensive fishy smelling discharge with no vulval soreness. pH > 4.5 |
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SEs of bacterial vaginosis |
increased risk of preterm delivery, development of PID and endometriosis following birth, infection post hysterectomy |
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Treatment for bacterial vaginosis |
Metronidazole 400mg bd for 5 to 7d or 2g single dose or Clindomycin 2% cream nocte PV for one week |
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Treatment of vaginal Candidiasis |
Clotrimazole pessary Fluconazole 150mg stat, again after 3d if severe (CI if breast feeding or pregnant) |
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What is required for diagnosis of pcos |
2 of the following; 1. Oligomenorrhea and/or anovulation 2. Hyperandrogenism 3. Polycystic ovaries. Defined as >12 follicles in each ovary measuring 2 - 9mm in diameter and or ovarian volume >10cm cubed "string of pearls" sign
of note: 1 in 3 premenopausal women will have PCOS on US and 1 in 3 of these will have PCOS |
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Management of PCOS |
1. weight loss and exercise 2. If oligomenorrhoeic consider progesterones to induce withdrawl bleed every 2 to 3 months. Consider COC pill to regulate menstration. COCs with anti androgen (co-pyrindiol) may decrease Acne/hirsuitism 3. Clomifene can be used to induce ovulation 4. Metformin |
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When can copper IUD be inserted for contraception |
Up to 5 days after sexual intercourse or 5 days after earliest expected date of ovulation irrespective of irrespective of time since sexual intercourse |
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What is treatment of Menorrhagia |
1. mirena coil ( if at least 12monts use is anticipates) 2. transexamic acid or NSAIDs or OCP 3. Norehiterone (15mg) daily from day 5 to 26 |
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What does T score measure |
Absolute fracture risk. Less than -2.5 is osteoporosis |
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whats a Z score |
Individuals relative risk for their age compared with reference values of same age |
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What is Tibilone |
Weak agonist to oestrogen/progesterone and Androgens. Used in same way as combined HRT. Used in treatment of post menopausal osteoporosis and endometriosis. Used for menopausal symptoms such as vaginal atrophy, libido, vaginal atrophy |
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What is continuous combined HRT |
has continuous progesterone to induce endometrial atrophy. Has no withdrawl bleed. Should only be given to women who have NOT had a period in last 12 months or who are premenopausal |
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what reduces hot flushes on Tamoxifen |
Clonidine |
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How is the menopausw diagnosed |
usually clinically with amenorrhoea >12/12 and no other cause. If in doubt confirm with FSH >30iu/L on 2 occasions >2 months apart |
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When should menopausal women use contraception |
>50 use for one year post last period. <50 use for two years post last period |