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48 Cards in this Set
- Front
- Back
character
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heritable feature that varies amont individulas
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trait
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each variant for a character
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true breeding
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produce only the same variety as the parent plant
ex) plant with purple flowers is true breeding if the seeds produced by self-pollination in successive generations |
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hybridiztion
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crossing of two true breeding varieties
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law of segregation
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two alleles for a heritable character segregate (separate from each other) during gamete formation and end up in different gametes
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homozygous
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organism that has a pair of identical alleles for a character
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heterozygous
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organism that has two different alleles for a gene
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testcross
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breeding an organism of unknwon genotype with a recessive homozygote, reveal the genotype of that orgnaimsm
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multiplication rule
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states that to determine this probability, we multiply the probability of one event by the probability of the other event
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addition rule
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the probability that any one of two or more mutually exclusive events will occur is calculated by adding their individual probabilities
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complete dominance
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one allele was dominant over the other, phenotypes of the heterozygote and dominant homozygote the same
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incomplete dominance
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neither allele is completely dominant, hybrids have a phneotype somewhere between those of the two parental varieties
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codominance
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two alleles can affect the phenotype in separate, distinguishable ways ex) human blood
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Tay-Sachs
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only childrent who inherit two copies of the tay sachs allele have the disease, recessive gene
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pleiotropy
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"more", one gene has multiple phenotype effects
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epistasis
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"standing upon" phenotype expression of a gene at one locus alters that of a gene at a second locus
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polygenic inheritance
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additive effect of two or more genes on a single phenotype character (converse of pleiotropy)
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norm of reaction
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phenotype is associated with a range of phnotypic possibilities due to environmental factors
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multifactorial
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many factors, bot genetic and environmental, collectively influence phenotype
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carriers
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phenotypically normal with regard to disorder heterozygoes may transmit recessive allele to offspring (albinism, cystic fibrosis)
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dominantly inherited disorders
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achondroplasia, dominant allels that cause a lethal disease much less common that recessive allels that have lethal effects
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chromosome theory of inheriance
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mendelian genes have specific loci (positions) along chromosomes, and chromosomes undergo segregation and independent assortment
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wild type
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phenotype for a character most common in natural populations
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sex linked gene
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a gene located on either sex chromosome
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linked genes
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genes located enar each other on the same chromosome tend to be inherited together
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genetic recombination
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the production of offspring the combinations of traits that differ from those found in either parent
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genetic map
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ordered list of the genetic loci along a particular chromosome
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linkage map
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genetic map based on recombination frequencies
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nondisjunction
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members of a pair of a homologous chromosomes do not move apart properly during meiosis I or sister chromatids fail to separate during meiosis II
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aneuploidy
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abnormal number of particular chromosome
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deletion
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occurs when a chromosomal fragment is lost
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duplication
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deleted fragment may become attached as an extra segment to a sister chromatid
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inversion
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chromosomal fragment could attach to a non-sister chromatid of a homolgous chromosome
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translocation
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fragment to join a nonhomologous chromosome
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genomic imprinting
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traits depend on which parent passed along the alles for those traits
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transformation
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change in phenotype and genotype due to the assimilation of outside DNA
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bacteriophages
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bacteria eaters
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virus
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DNA or RNA enclosed by protective coat
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chargaff's rules
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1) base combination varies between species
2)within a species, number of A and T are equal, number of C and G are equal |
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antiparallel
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subunits run in opposite directions
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semiconservative model
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each 2 daughter molecules have one old strand
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origins of replicaton
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replication of DNA begins at particular sites
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Replication fork
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y shaped region, parental strands of DNA are being unwound
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helicases
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enzymes that untwist the double helix at the replication forks, separating the two parental stands
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single strand binding proteins
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bind to unpaired DNA stands, keeping them from re-pairing
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topoisomerase
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helps relieve strain by breaking, swiveling and rejoining DNA stands
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primase
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starts complementary chain, adding RNA nucleotides one at a time
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DNA polymerase
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catalyze the synthesis of new DNA by adding nucleotides to preexisting chain
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