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8 Cards in this Set
- Front
- Back
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What are the main reservoir for Francisella? |
Rabbits! |
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How do humans get Francisella? |
More commonly through a tick bite - Dermacentor tick But also could be through direct contact |
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WHy is it mandatory to report cases of tularemia to the CDC? |
because it could be aerosolised and used as bioterrorist attack. |
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Francisella is a gram ________ ___________. and _________ intracellular |
negative coccobacilli facultative |
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Francisella infection depends on ______-mediated immunity. WHy is this significant? |
cell-mediated. THis is important because it helps it spread from one site of infection to the rest of the body. |
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Bacteria enters at the site of the bite and produces a what? Once it enters where does it go and what does it cause? |
painful ulcer [rabbit hole] gets into macrophages and travels to reticuloendothelial organs (lymph nodes) and causes granulomas with caseating necrosis. [collection of radishes underground that are rotting in the center] |
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If you get granulomas in the lymph nodes, what do you get externally? |
regional lymphadenopathy |
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Treatments? |
aminoglycosides [sai gardening tool] |
