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147 Cards in this Set

  • Front
  • Back

Nature vs. Nurture

Genetic predisposition vs. the environment

Epigenetics

Environmental influence over gene expression

Monism

Mind & Body are "one"


Bidirectional relationship


Mind is product of brain


Neuroscience supports it

Dualism

The mind & body are separated

Plasticity

Consistent changes in behavior can lead to long lasting/permanent changes in the physiology of the organism

Consciousness

Awareness of and ability to communicate about ones thoughts, perceptions, memories and feelings

Phenomena that challenges our understanding of consciousness

Blindsight


Unilateral Neglect


Split Brain Surgery

Split Brain Operations

Corpus callosum is cut to control seizures


No communication between hemispheres

Hippocrates

Believed the Brain was involved in sensation and intelligence

Aristotle

Believed the Brain was a cooling apparatus for the blood

Galen

Deducted that the ventricles of the Brain hose the "humors" fluids

"Humors" fluids

Are involved in sensations and movement by acting through hollow tubes called nerves

Descartes

Supported a fluid theory of body movement and proposed the theory of reflexes

Galvani

Nerves functioned like "wires"


Believed that one nerve processed both sensation and movement

Bell & Magendie

Discovered there were separate nerves for sensation and movement

Muller's Doctrine of Specific Nerve Energies

All neurons say the same thing...(excitation or inhibition) the message that is sent is determined by where the neuron is located

Helmholtz

Determined that neurons communicated using chemicals

Francis Gall: Phrenology

Protrusions on the surface of the skull can describe personality strengths

Florens: Brain Ablations

Systematic removal of brain areas and observing loss of function


Concluded there was no localization of function in the cortex

Penfield

Claimed to be able to elicit memories by stimulating the cortex of awake patients during surgery

Paul Broca

Localized Speech Area


Central sulcus

Central Nervous System

Brain & Spinal Cord

Peripheral Nervous System

Somatic & Autonomic

Somatic

Interact with the environment (external)

Autonomic

Interact inside environment


Sympathetic: "arousal"


Parasympathetic: "calm"

Glia cells

Most common cells in the Nervous System. Aren't excitable and don't communicate

Function of Glia Cells

Provide support for neurons (astrocytes)


Structural, nutritional, developmental


Housekeeping (phagocytosis)


Myelinated axons (insulation)


Form the blood brain barrier (toxins out)

Sensory Neurons

Afferent (you do something)

Motor neuron

Efferent (allow muscles to contract)

Interneuron

Sends message (yes or no)

Neuron Doctrine

Nervous system is made up of discrete cells called neurons. Info is transmitted from cell-cell across the synaptic space

Nissil Stain

Cell bodies

Golgi Stain

Stains for cell body & neurites

Dendrite

Receivers

Soma ("cell body")

Holds nucleus - dendrites attached to it

Axon

The conducting fiber

Axon Hillock

Where the cell body and axon meet & action potential occurs here

Terminal Button

Communicates w/ neighboring dendrites.


Electrical signals turns into chemical signals

Synapse

Space between Terminal Buttons & Dendrites


(Communicates w/ neuron A and neuron B)

Synaptic Cleft

Space

Multipolar Neuron

1 axon & Many dendrites (multiple inputs)

Bipolar Neuron

1 axon & 1 dendrite attached to its soma (cell body)

Unipolar neuron

1 axon attached to its soma


The axon divides, with 1 branch receiving sensory info & the other sending info into the CNS

Membrane

Structure consisting principally of lipid molecules that defines the outer boundaries of a cell

Electrode

A conductive medium that can be used to apply electrical stimulation to/or record electrical potentials

Microelectrode

Very fine, generally used to record activity of individual neurons

Oscilloscope

Lab instrument capable of displaying a graph of voltage as a function of time on the face of a cathode ray tube

Neurites

Something coming off of the cell body (soma)

2 basic electrical potentials in an axon

Resting & Action

Resting Potential

When a cells not conducting a signal, it's "at rest".


Negative electrical charges fluid on inside surface of membrane not outside

What is the membrane potential of a neuron at rest?

Approx. -65 mV or -70 mV

Action Potential

Reversal of Resting Potential Inside of the cell is more positive relative to the outside of the cell

Na+ is more concentrated ____ the cell at rest

Outside

Which direction is Na+ going? (In or out)

In

K+ is more concentrated ____ the cell at rest

Inside

Which direction is K+ going? (In or out)

Out

Cl- is more concentrated ____ of the cell at rest

Outside

Which direction is Cl- going? (In or out)

In

Depolarization

Membrane Potential becomes more positive than at rest


(Increases)

Hyperpolarization

Membrane potential becomes more negative than at rest


(Decreases)


Refractory Period

Diffusion

Movement of molecules from a region of high concentration to region of low concentration

Electrostatic Pressure

Attractive force between atomic particles.


Opposite signs attract


Same signs repel

Ion Channel

A specialized protein molecule that permits specific ions to enter or leave the cell

Voltage-Dependent Ion Channel

Opens or closes according to the value of the membrane potential

Chemical-Dependent Ion Channel

Opens or closes in response to a chemical binding to the receptor "coupled" to the ion channel

Na+/K+ Pump

Pumps 2 K+ in the membrane


Pumps 3 Na+ out of membrane


To correct concentration difference & sets everything back to rest

Conduction Velocity

The speed of propagation of action potentials


Varies with the diameter of the axon


Larger = faster

Nodes of Ranvier

Small gaps in the insulating myelin sheath

Saltatory Conduction

The action potential jumps from node to node

When neurotransmitter binds to postsynaptic receptor these small proteins are activated

G-Proteins

Neuromodulator

Indirect - binds to metabotropic receptors

Postsynaptic Potentials

Alterations in the membrane potential of a postsynaptic Neuron, in response to neurotransmitter release at the synapse

Excitatory Postsynaptic Potentials (EPSP)

Na+ channels


Depolarization of the membrane

Inhibitory Postsynaptic Potentials (IPSP)

K+ & Cl- channels


Hyperpolarization of the membrane

Reuptake

When molecules of a neurotransmitter are released into the synaptic cleft are transported back into the terminal buttons

Enzyme Deactivation

The destruction of a neurotransmitter by an enzyme after its release

Autoreceptors

A receptor molecule located on the presynaptic Neuron that


Regulates synthesis and the release of a neurotransmitter.

Synaptic Integration

Process which inhibitory & excitatory Postsynaptic Potentials summate and control the rate of firing of a neuron

Spatial Summation

"Space" (based on location)


When 2+ presynaptic inputs are active at the same time

Temporal Summation

"Timing"


When the same presynaptic fiber fires action potentials and the individual EPSP's add together

Gap Junctions

Electrical synapses located in the heart


Action potentials can jump directly to the postsynaptic region without being transformed into a chemical signal

Ligand

A neurochemical that binds to a receptor

Endogenous Ligand

Comes from within

Exogenous Ligand

Externally administered


We put them into our system

Agonists

Binds to the receptor and activates the receptor in a similar fashion as the endogenous ligand

Antagonists

Binds to the receptor and blocks/prevents the endogenous ligand from binding

Neuraxis

Imaginary line drawn through the center of the length of the CNS, from the bottom of the spinal cord to the front of the forebrain

Anterior vs. Posterior

In front vs. In back

Rostral vs. Caudal

"Rooster beak" (out) vs.


"horse tail" (down)

Dorsal vs. Ventral

"Dolphin fin" (top) vs. "stomach" (bottom)

Lateral vs. Medial

"Ears" (side) vs. "Nose" (center)

Ipsilateral vs. Contralateral

Same aside vs. Opposite side

Anatomical Cuts

Cross Section/Frontal Section/Coronal (Razor head band)



Horizontal section "helicopter"



Sagittal Section "cut like bread"

Dura Mater

Tough membrane

Arachnoid Membrane

Weblike Appearance

Subarachnoid Space

Blood Vessels & Cerebrospinal Fluid (CSF)

Pia Mater

Right on top of the brain

Nervous System Tissue

Brain, Spinal Cord, Cranial Nerves

Olfactory Nerve

Sense = Smell

Optic Nerve

Sense = Vision

Optic Nerve

Sense = Vision

Oculomotor Nerve

Motor = eye movement/pupil

Trochlear Nerve

Motor = Eye Movement

Trigeminal Nerve

Sense = face


Motor = chewing

Abducens

Motor = eye movement

Facial Nerve

Sense = taste


Motor = face

Auditory-Vestibular

Sense = hearing & balance

Glossopharyngeal

Sense = taste


Motor = throat

Vagus

Motor = parasympathetic (relaxed)

Spinal Accessory

Motor = threat & neck

Hypoglossal

Motor = tongue

Dorsal Root

The spinal root that contains incoming (afferent) sensory fibers

Ventral Root

The spinal root that contains the outgoing (efferent) motor fibers

Spinal Cord Matter

White Matter (fat) = outside


Gray Matter (cells) = inside

Cervical

"Breakfast"


7

Thoracic

"Lunch"


12

Lumbar

"Dinner"


5

Sacral & Coccyx

Fused

Ventricle System

4 hollow spaces inside rain containing Cerebrospinal Fluid (CSF)

Cerebrospinal Fluid (CSF)

Produced by choroid plexus (tissue located within the ventricles)


"Black Cottage Cheese"

Hydrocephalus

Blockage of a ventricle

CSF Function

Supports the weight of the brain (buoyant)


Helps reduce shock to the CNS caused by sudden head movements

Cerebral Ventricles

Lateral (1 & 2)


3rd


Cerebral Aqueduct


4th

Cerebral Aqueduct

A narrow tube interconnecting the 3rd and 4th ventricles of the brain

Forebrain

Sense/Separates us from other animals (inhibitory)


1.) Telencephalon


2.) Diencephalon

Midbrain

Keeps species alive behaviorally (maternal)


1.) Mesencephalon

Hindbrain

Keeps life physiological (life or death)


1.) Metencephalon


2.) Myelencephalon



Telencephalon

Lateral ventricles (1 & 2)


- Cerebral Cortex


- Basal Ganglia


- Limbic System

Diencephalon

(3rd ventricle)


- Thalamus


- Hypothalamus

Mesencephalon

(Cerebral Aqueduct)


- Tectum: "roof"


- Tegmentum: "floor"

Metencephalon

(4th ventricle)


- Pons


- Cerebellum

Myencephalon

- Medulla

Telencephalon

- Cerebral hemispheres (cortex): convolutions


- Sulcus: in between (folds)


- Fissure: deep grooves


- Gyrus: surface of brain (bumps)

Temporal Lobe

Ventral to Lateral Fissure

Occipital Lobe

Visual info, back of brain

Frontal Lobe

Motor behavior & to control impulses, plan, hypothetical thinking.


(Dorsal to lateral fissure)

Parietal Lobe

Posterior/coutal to central fissure


Somatosensory (senses)

Limbic System

Thalamus, amygdala, hippocampus, limbix cortex & parts of the hypothalamus

Hippocampus

Ability to form long term memories


"Seahorse"

Amygdala

End of the hippocampus


Emotional processing


Very plactic

Basal Ganglia

Ability to move & function


Includes the caudate nucleus, the globus pallidus, & putamen

Thalamus

Major relay station for sensory info


"Train station"

Hypothalamus

Controls the Autonomic Nervous System (ANS)


Organized behavior under hormonal control: fighting, feeding, fleeting & mating

Tegmentum ("covering")

Floor/Bottom


Periaqueductal gray matter


Substantial nigra: ("black substance")

Tectum

Superior colliculi (vision): Primitive Visual System



Inferior colliculi (audition):


Primitive Hearing System

Metencephalon

- Cerebellum ("little brain"): hand eye/coordination & learning that doesn't have to be consciously aware



- Pons ("bridge"): gateway for axons & reticular formation from the medulla


Buldge


Myelencephalon

-Medulla oblongata:


Lots of nuclei that keep you alive...without it = fatality



-Reticular Formation:


Keeps you awake & aroused (aware)


Losing arousal, neurons stop firing


Coma like state, but not sleeping