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56 Cards in this Set

  • Front
  • Back
Optic grooves are extensions of the ___ ___ and so they are lined by ___ ___.
extensions of the NEURAL TUBE
lined by NEURAL ECTODERM
During eye development, optic grooves extend outward into larger structures called ___ ___.
optic vesicles
What stimulates the formation of the lens placode?
What does this stimulation of the lens placode do in return?
optic vesicles coming into close contact with surface ectoderm

in return, the lens placode will stimulate the optic vesicle to continue forming and to form an optic cup
What is the choroid fissure? What does it do?
gap that is left along the ventral surface of the optic cup as it invaginates

allows passage for hyaloid vessels from the brain into the lens
Hyloid vessels will _____ and only be present in the adult where?
will DEGENERATE and only be present in the adult in the optic stalk & retina
What is the optic stalk?
connection of the optic cup to the forebrain
The optic cup has 2 layers. An inner and an outer. Which one is thick and which one is thin?
inner - thick (10 cell layers)
outer - thin (1 cell layer)
The inner layer of the optic cup develops into what 2 things?
1 - pars optica retina
-from the posterior 4/5ths
-"neural retina" for vision

2- pars ceca retina
-from its anterior 1/5
-non-visual tissues (ciliary body & iris)
The outer layer of the optic cup becomes what?
retinal pigmented epithelium
The basis for retinal displacement lies in the fact that....
the space between the inner and outer layer of the optic cup persists (gets smaller through eye development but is still a space)
True or False: Light has to travel all the way through the retina to get to the photoreceptors and then travel all the way back.
True.
The ciliary body and iris develop from what?
pars ceca retina which is the anterior 1/5th of the inner layer of the optic cup
The ciliary body produces ___ ___ which is important for normal eye maintenance.
aqueous humor
Ciliary muscles are formed from?

Ligaments of these muscles control what?
neural crest

ligaments of these control lens shape for vision adjustment
The pigmented part of the eye is called the ___. The pigmentation is due more so to melanocytes in the ___ rather than the ____.
iris

more so due to melanocytes in the STROMA rather than the epithelium
Muscles of the iris are formed from what? Function?
neural crest
function to open/close the pupil
The lens placode will form a ___ that will then detach from the surface to become a ____ ____ surrounded by the optic cup.
will form a PIT
detaches and becomes a LENS VESICLE
Posterior cells of the lens vesicle will ______ to become lens ____.
will ELONGATE to become lens FIBERS
The optic cup comes from ____ ___ and the lens placode comes from ___ ___.
optic cup from NEURAL ECTODERM and lens placode from SURFACE ECTODERM
The choroid, sclera, vitreous body, and part of the cornea all form from specializations of what?
neural crest
What stimulates the formation of the choroid from neural crest? What is the choroid?
the optic cup stimulates

the choroid is a vascular bed (layer of blood vessels) adjacted to the retinal pigmented epithelium
What is the white of the eye called? Formed from? function?
sclera
formed from neural crest
function is supportive
What is the vitreous body?
a gel like part of the eye formed from neural crest
How are the eyelids formed?
surface ectoderm folds in on itself
The cornea is formed partially from ___ ___ and partially from ___ ___.
neural crest and surface ectoderm
Where is the anterior chamber of the eye?
between the surface ectoderm of the cornea and the lens
An intermediate membrane that is between the cornea and the lens is called the ___ membrane. It normally degrades but occasionally does not.
PUPILLARY membrane.
The central arteries and veins of the eye in the adult were once the ____ vessels.
HYALOID vessels
The optic stalk will become the ___ ___ in the 6th to 9th week of development. How?
optic nerve

retina differentiates --> ganglion cells extend long axons --> axons fill up the optic stalk --> optic nerve
The master switch for eye development is called ____ __.
Pax 6
A mutation in pax 2 can lead to _____ which is when the ___ ___ does not resolve.
coloboma

choroid fissure does not resolve
What are 2 eye defects associated with mutations in pax 6?
microphthalmia (small eye)
anophthalmia (no eye)
A persistent iridopupillary membrane is a .....?

Causes?
remnant of neural crest in the anterior chamber

Causes a web of tissue interfering with vision
Where does the inner ear develop?
within the petrous portion of the temporal bone of the skull
Fill in the blanks.
otic placode --> otic ___ --> otic vesicle --> ____ ____ ____
otic placode --> otic pit --> otic vesicle --> 3 part sac
The utricular portion of the otic vesicle will become what?
semicircular canals of the inner ear
The semicircular canals of the inner ear function to do what?
sense movement for balance/rotation
The saccular portion of the otic vesicle will become what?
the cochlear duct
Where is the organ for hearing contained? What is it called?
contained in the cochlear duct
called the Organ of Corti
What is the cochlear duct?
extension of the saccular portion of the otic vesicle
Inner ridge cells of the cochlear duct become what?
tectoral membrane
Outer ridge cells of the cochlear duct differentiate into what?
hair cells
Hair cells of the cochlear duct are innervated by what?
vestibulocochlear (CN VIII)
What are the 3 cavities that form around the cochlear duct?
scala tympani - underneath duct
scala vestibule - above duct
scala media = lumen of duct
Dilated areas at the ends of the semicircular canals are called ___ ____.
crus ampullare
(the ampulla)
(crista ampullaris)
Hair cells of the semicircular canals are embedded in the ____, a gelatinous mass. (Each canal has 1)
cupula
The middle ear consists of the ____, ____, and ____. The (first 2) form from branchial arch __ and the (last one) forms from branchial arch __.
malleus, incus, and stapes

malleus & incus from branchial arch 1
stapes from branchial arch 2
The cavity of the middle ear (auditory tube) forms from what?
extension of branchial pouch 1
The external acoustic meatus of the middle ear forms from what?
branchial groove 1
The tympanic membrane of the ear forms from what?
branchial membrane 1
When sound hits the tympanic membrane (ear drum) it travels from where to where? about 8 steps
malleus --> incus --> stapes --> oval window of inner ear --> vibrations to scala tympani fluid --> movemnt in basilar membrane of the Organ of Corti --> hair cells move --> sound perception
What are the 2 muscles of the middle ear? Where does each form from?
tensor tympani from branchial arch 1
stapedius from branchial arch 2
The tensor tympani muscle of the middle ear is innervated by? What is its function?
innervation: V3 of trigeminal
function: protect ear from too strong of vibrations (loud noises)
The stapedius muscle of the middle ear is innervated by? Function?
innervation: facial nerve
function: prevents stapes from hitting the round window too hard
The auricle develops in the area of the first and second branchial arches as _ (#) ____ ____.
6 auricular hillocks
Auricular hillocks (which develop into the auricle) are covered in ____ ____ but are internally composed of ____ ____.
covered in SURFACE ECTODERM
internally composed of NEURAL CREST