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8 Cards in this Set
- Front
- Back
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What are the physiological properties of HPV?
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Human Papilloma Virus:
1. DS DNA circular 2. Naked (non-enveloped) |
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How does HPV replicate and where do they develop?
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It depends on the host DNA replication proteins to reproduce.
HPV develop in granular cells close to the final keratin layer. |
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What are the possible outcomes of HPV infections?
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1. Cutaneous = skin warts
2. Mucosal = (a) benigh head and neck tumors (b) condyloma acuminatum/anogenital warts (c) cervical intraepithelial neoplasia, cancer* *Koilocytes seen on PAP |
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What are the general characteristics of family chlamydiaceae?
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gram (-) cocci
obligate intracellular energy parasite sensitive to tetracycline and macrolides |
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What are the basic physiological properties of Neisseria gonorrhoeae?
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Neisseria species:
1. aerobic, glucose fermenters 2. nonmotile, non-spore forming N. gonorrhoeae: 1. Noncapsulated bateria 2. Sensitive to drying and cold 3. oxidase & catalase-positive |
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What are the virulence factors in N. gonorrhoeae?
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1. Pilin
2. Other membrane protein: (a) Por protein (OMP I, oporin) - prevents phagolysosome fusion in neutrohils 3. LOS (lipooligosaccharide endotoxin) 4. IgA protease - destroying IgA to prevent opsonization 5. Beta lactamase - hydrolyzes the beta-lactam ring in PCN (b) Opa protein (OMP II) - tight binding and invasion, attachment |
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What are the general features of Herpes viridae family?
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1. DS DNA virus
2. enveloped |
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How do you diagnose HSV?
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Rapid test Tzanck smear to demonstrate multi-nucleated giant cells
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