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10 Cards in this Set
- Front
- Back
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Which type of cancer is colon CA most commonly
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Adenocarcinoma
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Ranking of colon CA
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3rd most common cancer overall
2nd leading cause of cancer death |
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Epidemiology of colon CA
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after age 50, peak at 65
slightly more in men more common in blacks and Ashkanazi jews |
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Risk factors for colon CA
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diet high in red and processed meats.
sedentary lifestyle/obesity Smoking EtoH use Hx of polyps or IBD FMH Hx of FAP or HNPCC (Lynch syndrome), Peutz-Jeghers syndrome DM II |
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Screening for colon CA
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Start at age 50 until age 75
Best: Colonoscopy every 10 yrs Flex Sig plus FOBT every 5 yrs FOBT every year. |
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Presentation of colon CA
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Varies with location of polyp/mass.
R-sided: ulcerate more commonly, may only have anemia w no change in BMs. Transverse and L-sided: abd cramping, decreased stool caliber or obstruction. Rectosigmoid: hematochezia, tenesmus, decreased stool caliber. |
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Workup for colon CA
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Colonoscopy of entire colon w/ bx.
Evaluate for mets with an Abd CT, CXR. Preop CEA level CBC-for anemia Barium enema may also be used--apple core appearance |
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Tx for colon CA
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Surgical resection.
Mets can be treated with adjuvant chemo or radiation. Liver mets can be resected. |
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F/u after tx for colon CA
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CEA w office visit at least every 4 months the first 2 yrs. Colonoscopy every 3 yrs.
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Recurrence of colon CA
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Recurrence usually occurs 3-4 yrs after tx. So survival at 5 yrs is a good indication of cure.
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