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27 Cards in this Set
- Front
- Back
communication between cells
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- involves secreted signaling molecules
- producing cell. - receiving cell: have target receptors that bind signal molecules specifically |
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short distance cell to cell signaling
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- paracrine signaling: neighbor to neighbor.
- autocrine signaling: self signaling. |
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long distance cell to cell signaling
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- endocrine signaling via endocrine cells or glands (ductless)
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types of intercellular communication using secreted molecules
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- synaptic signaling: local. neurotransmitters. synaptic signaling across synapse.
- neuroendocrine signaling: long distance. into bloodstream. |
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hormones target specific cells, triggering specific _____ _____.
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response pathways
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chemical classes of hormones
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- differ depending on solubility
- polypeptide (water soluble) - steroid (a lipid, lipid soluble) - amine (both) |
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major endocrine glands
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- hypothalamus
- pineal gland - pituitary gland - thyroid gland - parathyroid gland - adrenal glands - pancreas - kidney - ovaries/testes |
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organs containing endocrine cells
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- thymus
- heart - liver - stomach - kidney - small intestine |
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insulin and glucagon
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- antagonistic hormone pairs
- insulin: causes blood glucose levels to decrease - glucagon: causes blood glucose levels to increase |
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posterior pituitary
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- secreted through neurons.
- example of hormones: ADH, oxytocin. |
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anterior pituitary
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- under the control of the hypothalamus' releasing hormones
- hormones produces in response to releasing hormones: tropic and nontropic hormones, or both. - secreted through portal vessels. |
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tropic hormones
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- regulates function of endocrine cells or glands. has another gland as a target.
- produced by anterior pituitary - examples: FSH and LH (to testes/ovaries), TSH (thyroid), GH |
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nontropic hormones
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- do not regulate function of endocrine cells or glands
- produced by anterior pituitary - examples: prolactin (mammary glands), GH |
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growth hormone
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- has tropic and nontropic effects
- tropic effect: liver (IFGs - stimulate bone and cartilage growth. effects on aging) - nontropic: diverse metabolic functions |
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too much growth hormone
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- gigantism: as a child
- acromegaly: as an adult |
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too little growth hormone before puberty
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dwarfism
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endocrine pancreas
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- homeostasis: blood glucose levels
- blood glucose levels rise -> insulin released into blood -> liver and body cells store glucose as glycogen -> blood glucose decreases - blood glucose levels fall -> glucagon released into blood -> liver breaks down glycogen into glucose to release into bloodstream -> blood glucose levels rise |
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thyroid gland
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- releases T3, T4, and calcitonin
- calcitonin regulates blood calcium levels by decreasing it. |
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parathyroid
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- releases PTH as antagonistic hormone of calcitonin.
- raises blood calcium levels. |
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adrenal cortex
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- sits on top of the kidney (adrenal)
- produce corticosteroids in in response to long-term stress |
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corticosteroids
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- glucocorticoids: proteins and fats broken down and converted to glucose, leading to increased blood glucose. possible suppression of the immune system.
- mineralocorticoids: rentention of sodium ions and water by kidneys. increased blood volume and blood pressure. |
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pineal gland
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- produces melatonin
- secretion is influenced by light. - responsible for biorhythms. |
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gonadal sex hormones
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- androgens and estrogens
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adrenal glands
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- adrenal cortex: true endocrine cells
- adrenal medulla: neurosecretory cells - involved in stress response |
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adrenal medulla
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- middle of the adrenal gland
- controlled by nerve signals from the hypothalamus - short term stress response |
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adrenal cortex
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- outer layer of adrenal gland
- controlled by the release of ACTH - released by anterior pituitary - long term stress response |
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catecholamines
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- released by
- epinephrine and norepinephrine - increased blood pressure, breathing rate, metabolic rate |