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27 Cards in this Set

  • Front
  • Back
communication between cells
- involves secreted signaling molecules
- producing cell.
- receiving cell: have target receptors that bind signal molecules specifically
short distance cell to cell signaling
- paracrine signaling: neighbor to neighbor.
- autocrine signaling: self signaling.
long distance cell to cell signaling
- endocrine signaling via endocrine cells or glands (ductless)
types of intercellular communication using secreted molecules
- synaptic signaling: local. neurotransmitters. synaptic signaling across synapse.
- neuroendocrine signaling: long distance. into bloodstream.
hormones target specific cells, triggering specific _____ _____.
response pathways
chemical classes of hormones
- differ depending on solubility
- polypeptide (water soluble)
- steroid (a lipid, lipid soluble)
- amine (both)
major endocrine glands
- hypothalamus
- pineal gland
- pituitary gland
- thyroid gland
- parathyroid gland
- adrenal glands
- pancreas
- kidney
- ovaries/testes
organs containing endocrine cells
- thymus
- heart
- liver
- stomach
- kidney
- small intestine
insulin and glucagon
- antagonistic hormone pairs
- insulin: causes blood glucose levels to decrease
- glucagon: causes blood glucose levels to increase
posterior pituitary
- secreted through neurons.
- example of hormones: ADH, oxytocin.
anterior pituitary
- under the control of the hypothalamus' releasing hormones
- hormones produces in response to releasing hormones: tropic and nontropic hormones, or both.
- secreted through portal vessels.
tropic hormones
- regulates function of endocrine cells or glands. has another gland as a target.
- produced by anterior pituitary
- examples: FSH and LH (to testes/ovaries), TSH (thyroid), GH
nontropic hormones
- do not regulate function of endocrine cells or glands
- produced by anterior pituitary
- examples: prolactin (mammary glands), GH
growth hormone
- has tropic and nontropic effects
- tropic effect: liver (IFGs - stimulate bone and cartilage growth. effects on aging)
- nontropic: diverse metabolic functions
too much growth hormone
- gigantism: as a child
- acromegaly: as an adult
too little growth hormone before puberty
dwarfism
endocrine pancreas
- homeostasis: blood glucose levels
- blood glucose levels rise -> insulin released into blood -> liver and body cells store glucose as glycogen -> blood glucose decreases
- blood glucose levels fall -> glucagon released into blood -> liver breaks down glycogen into glucose to release into bloodstream -> blood glucose levels rise
thyroid gland
- releases T3, T4, and calcitonin
- calcitonin regulates blood calcium levels by decreasing it.
parathyroid
- releases PTH as antagonistic hormone of calcitonin.
- raises blood calcium levels.
adrenal cortex
- sits on top of the kidney (adrenal)
- produce corticosteroids in in response to long-term stress
corticosteroids
- glucocorticoids: proteins and fats broken down and converted to glucose, leading to increased blood glucose. possible suppression of the immune system.
- mineralocorticoids: rentention of sodium ions and water by kidneys. increased blood volume and blood pressure.
pineal gland
- produces melatonin
- secretion is influenced by light.
- responsible for biorhythms.
gonadal sex hormones
- androgens and estrogens
adrenal glands
- adrenal cortex: true endocrine cells
- adrenal medulla: neurosecretory cells
- involved in stress response
adrenal medulla
- middle of the adrenal gland
- controlled by nerve signals from the hypothalamus
- short term stress response
adrenal cortex
- outer layer of adrenal gland
- controlled by the release of ACTH
- released by anterior pituitary
- long term stress response
catecholamines
- released by
- epinephrine and norepinephrine
- increased blood pressure, breathing rate, metabolic rate