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153 Cards in this Set

  • Front
  • Back

abdominal pain, N/V in an elderly woman w/diabetes




1st step?

ECG

MI Lab Tests




1. Sensitive for new MI




2. Sensitive for re-occlusion < 10 days from a previous MI

Tropoin




CK-MB

Ischemic chest pain w/exertion


Normal EKG




Next step?

Exercise stress test

Most common cause of cardiac arrest in MI

Reentrant ventricular arrhythmias

ECG in Inferior MI




Block vessel?

ST elevations in II, II, and AVF




RCA or LCX

ECG of anterior MI



Blocked vessel?

ST elevation in VI-6



LAD

RCA supplies what?




And what consequences?

1. Right Ventricle - RV dysfunction causes hypotension




2. AV node - dysfunction causes AV block




3. Hypotension & AV block causes bradycardia

Cocaine Toxicity




1. Symptoms




2. Treatment

1. Psychomoter agitation, dilated pupils, hypertension, acute MI, atrophic nasal mucosa




2. Benzodiazapine




D/N give B-Blocker!

Eccentric hypertrophy




Example

From chronic volume overload




aortic regurg

Dyspnea w/Increase pro-BNP




Another sign?

Congestive Heart Failure




S3 heard sound

Mechanical complications of MI




Timeline?

Free wall rupture of L. ventricle


Mitral regurge 2/2 papillary muscle rupture


Left Intraventricular septum rupture




3-7 days after MI when the infarcted myocardium is softest

Ventricular remodeling post MI can be lessened by what?

ACE inhibitor


B-Blocker

Lidocaine increases risk of what in MI?

Asystole

Pulseless electrical activity after MI




Suspect what?

Free wall rupture

Strongest influence on long-term prognosis in STEMI

Time that passes before restoration of coronary blood flow

What lab value parallels the severity of heart failure?




1. Why?




2. Treatment

Hyponatremia




Decreased perfusion at baroreceptors and renal arterioles --> Increased ADH, increased renin and increased norepinephrine --> Decreased Na+




Fluid restriction, ACE Inhibitor, loop diuretics

Persistent ST-elevation post MI w/deep Q waves in same leads




1. Timeline




2. Dx how?

Ventricular aneurysm




Late --> months




Dx: Echo

Right ventricular MI




1. Tx w/what




2. Avoid what

IV fluids to increase Preload




Avoid nitrates and diuretics which decreases Preload

What drugs to hold 48 hrs before stress testing?

B-Blockers, Ca2+ Channel blockers, Nitrates

Common cause of non-cardiac chest pain


(besides musculoskeletal)

Esophageal disorder (GERD)

Chest pain that is reproducible w/palpatation

musculoskeletal pain (costochondritis)

What drug to prevent cardiovascular disease in a diabetic patient?




Start when?

Statin




>= 40 yrs old

Statins



1. Inhibits what



2. Side effects

Intracellular HMG-COA Reductase Inhibitor



Hepatic dysfunction



Muscle weakness/tenderness (Rhabdo which can cause renal failure)

Stop what drug in pt w/increased creatine phosphokinase?

Statins




Rhabdo --> renal failure

What drug to give after unstable angina, NSTEMI, and PCI w/stent?

Clopidogrel




(anti-ADP platelet inhibitor)


P2Y12 inhibitor

Nitroglycerin pain relief mechanism

Dilation of capacitance vessels (veins)




dilation of veins --> decreased ventricular preload --> decreases O2 req




nitroglycerin also decreases afterload by dilating arteries but this is less significant in pain relief

Substernal discomfort, left-sided neck pain, diaphoresis, and dyspnea




1. Associated physical finding?

acute coronary syndrome (MI)



1. S4 heart sound 2/2 stiffening of L. ventricle




- S4 is normal in healthy older adults


Digoxin Use

Systolic heart failure




afib /a flutter

Nausea, vomiting, diarrhea, vision changes, and arrhythmia




Next step

Digoxin toxicity




Check drug levels

What meds d/n improve survival in pts w/CHF?

Digoxin & loop diuretics (furosemide)

MI w/bibasilar crackles halfway up the lung fields




Treatment?

Acute pulmonary edema




diuretics (furosemide)

Heart failure after traumatic thigh injury




Cause and mechanism

AV fistula




Increased preload, decreased SVR --> Increased CO --> heart failure

Concentric Hypertrophy




Examples?

From chronic pressure overload




aortic stenosis, hypertension

Pounding heart sensation and widened pulse pressure, water hammer pulse



1. Common causes (3)



2. Murmur?

aortic regurg



1. Rheumatic heart disease


Aortic root dilation (Marfans/syphilis)


Bicuspid aortic valve



2. Diastolic decrecendo

Treatment for viral pericarditus

NSAIDS (aspirin, naproxen, ibuprofen, indomethacin) and/or colchicine

Most common cause of mitral regurg

mitral valve prolapse from myxomatous degeneration

Side effect of dihydrophyridine Ca-channel blockers




Most common drug in this group?

peripheral edema




Amlodipine

Mid-diastolic murmur w/opening snap

mitral stenosis

Indicators for surgery in pt w/aortic stenosis

SAD: Syncope, angina, dyspnea

Marfan syndrome




1. genetics/mutation




2. Heart and lung issues

1. Autosomal dominant, Fibrillin-1




2. Aortic dissection, aortic root dilation --> aortic regurg, mitral valve prolapse




Spontaneous pneumothorax

Decrescendo early diastolic murmur




Cause in a young pt

aortic regurg




bicuspid aortic valve

acute mitral regurg increases what?

L. atrial and ventricular filling pressure

Blowing holosystolic murmur best heard over the apex with radiation to the axilla

mitral regurg

Systolic murmur at lower sternal boarder that increases with inspiration




Common in?

Tricuspid regurg




IV drug users

What murmurs should always be investigated and how

Diastolic and continuous murmurs as well as loud systolic murmurs




Echo

Symmetric duskiness/coolness of all fingertips

ischemia 2/2 norephinephrine-induced vasospasm

Symptoms of infectious endocarditis

Roth spot


Osler node


Joneway lesions

New conduction abnormalities in pt w/infective endocarditis

Perivalvular abscess

Palpitations, left and right ventricular dilation




Treatment?

Tachycardia-mediated cardiomyopathy




Rate or rhythm control

Effect of exercise or atropine on second degree heart blocks




What does the opposite?

exercise/atropine improves type I blocks and worsens type II blocks




Vagal maneuvers (carotid massage)

Peaked T waves

hyperkalemia

Third-degree or complete heart block

no conduction from atria to ventricle (p-waves are completely unrelated to QRS waves)

What arrhythmia is specific for digitalis toxicity?

paroxysmal


atrial tachycardia with AV block (2:1)

Common causes of exertional syncope

Ventricular tachycardia




L. ventricular outflow obstruction (aortic stenosis)

Constrictive pericardities




1. Symptoms


2. Jugular venous pressure tracing shows what


3. What heart sound?


4. Finding on x-ray


5. Causes

1. Decreased CO leading to dyspnea w/exertion


Venous overload (Increased JVP, ascites, edema, etc)


2. Sharp x and y descent


3. Pericardial knock (after S2)


4. Calcification around the heart


5. Virus, surgery/radiation, TB (China, India, Africa)

Treatment if stable or unstable

Treatment if stable or unstable

Ventricular Tachycardia




Unstable --> cardioversion




Stable --> antiarrhythmic

1. Pulseless electrical activity next step




2. V-fib or pulseless VT next step

1. CPR & vasopressor (epinephrine)




2. Defibrillation

Fixed splitting of S2

ASD

Aortic coarctation


pressure is greater in which arm?

R > L

Megacolon/megaesphophagus & heart disease in a pt from Latin America

Chagas - trypanosoma Cruzi (protazoan)

Cause of outflow obstruction in hypertrophic cardiomyopathy




Murmur?


Valsalva affects the murmur how?

1. Septal hypertrophy and abnormal mitral leaflet motion




2. Harsh crescendo-decrescendo murmur after SI




3. Increase

Mobitz type II



1. Define



2. Cause



3. Tx

Second degree heart block:


1. Unpredictable QRS drops without P-R prolongation



2. Block in His-Purkinje system



3. Pacemaker b/c can progress to third degree block

Patient from Cambodia w/dyspnea, cough, hemoptysis, palpitations, + irregular heart beats




- Cause of palpitations?

mitral stenosis 2/2 Rheumatic Fever




mitral stenosis --> atrial dilation --> a-fib

Low-voltage QRS complexes




Electrical alternans


(beat-to-beat variation in QRS)

Pericardial effusion / Cardiac Tamponade

Risk factors for premature atrial complexes?




Treatment

Tobacco


Alcohol


Caffeine


Stress




Decrease risks, Beta-blocker if symptomatic


Treatment


Treatment

Premature Ventricular complexes (wide QRS > 120ms)




Observation

Cause of long-term mortality in patients w/A-fib?




Treatment?

Thromboembolism




Warfarin if CHADS-VASc score is > 2

Anatomical cause of:




1. A-fib




2. A-flutter

1. Pulmonary veins




2. Tricuspid annulus


Paroxysmal supraventricular tachycardia (PSVT)
1. alleviating maneuvers
2. Drug that provides relief


Paroxysmal supraventricular tachycardia (PSVT)


1. alleviating maneuvers


2. Drug that provides relief

Abrubt increase in HR usually from AV-node reentry




1. Vagal maneuvers (Valsalva, carotid sinus massage, and immersion in cold water). This decreases conduction through the AV node


2. Adenosine

New onset a-fib




Check for what disease?




If positive, what drug tx?

Hyperthyroidism




B-blocker


Treatment?


Treatment?

Torsades de pointes




Unstable --> defibrillation


Stable --> IV magnesium


Next step?

Next step?

Ventricular Fibrillation




Defibrillation

Most important factors for survival in sudden cardiac arrest

Bystander CPR




Rhythm analysis




D-fib

First degree heart block




1. Define




2. Normal QRS - next step




3. Prolonged QRS - next step

1. Delayed transmission from atrium to ventricle (increased PR duration)




2. Delay in AV node --> observation




3. Delay below the AV node --> electrophysiology testing

Mobitz Type I




1. Alternative Name




2. Define




3. Treatment

Wenckebach




Second degree AV block: progressive prolongation of PR interval leading to QRS drops




No treatment necessary

Use dependance



1. Definition



2. What classes/drugs?

1. Increased pharmacologic effects w/increased HR



2. Class 1C - Na+ channel blockers - flecainide & propafenone



3. Class IV - Ca2+ channel blockers - Verapimil, diltiazem

Hepatojugular reflex




Sign of what

Push on stomach and see if JVP decreases




Sign of constrictive pericarditis, restrictive cardiomyopathy or R. ventricular MI if doesn't decrease

Non-cardiac causes of pulses of paradoxus

Asthma & COPD

Heart defects in Hemachromatosis

Dilated or restrictive cardiomyopathy




Conduction abnormalities

Uremic pericarditus - serum BUN?



Treatment?

Serum BUN > 60 mg/dL



Dialysis

Hypotension, distended neck veins, pulses paradoxus




Treatment?

Cardiac Tamponade




Pericardiocentesis

Beck's Triad

Hypotension


Distended neck veins


Muffled heart sound




(-BP, + JVP)




Sign of cardiac tamponade (decreased SV, CO, Preload)

Mechanism for pulses paradoxus

Inspiration --> intrathoracic pressure --> Increased venous return to R. ventricle --> intraventricular septum shifts towards L. ventricle --> decreased L. ventricular filling --> decreased systolic BP

Common kind of heart failure in constrictive pericarditus




Left or right?

R heart failure

Kussmaul's sign-define associated w/what disease?

Lack of decrease or an increase in JVP on inspiration




Constrictive Pericarditus

Name 3 antiarrhythmic drugs

amiodarone


lidocaine


procainamide

Restrictive Cardiomyopathy


1. Signs on echo


2. Disease causes (4)


3. Which is reversible?


4. Which if proteinuria & easy bruising?

Diastolic dysfunction, normal or thickened ventricles with normal ventricular volume




2. Amloidosis (4)


Sarcoidosis


Hemachromatosis (3) Reversible w/phlebotomy


Scleroderma

Bilateral basal crackles, increased JVP & pitting edema 2 wks after a cold


1. What kind of cardiomyopathy?


2. Organisms


3. Diagnose with?


4. Imaging shows what

Acute viral myocarditus


1. Dilated cardiomyopathy


2. Coxsakievirus B, parvo B19, HHV6, adenovirus, enterovirus


3. Echo


4. Dilated ventricles + diffuse hypokinesia

White granular patch over the buccal mucosa that can not be scraped off in an alcoholic/smoker

Leukoplakia




reactive pre-cancerous lesion from hyperplasia of the squamous epithelium

Bone conduction that is greater than air conduction on Rinne test




1. Common cause in adults

Conductive Hearing Loss




1. Otosclreosis

Pt w/hypertension




Get what labs? (4)

1. Urinalysis


2. Chemistry Panel


3. Lipid Profile


4. Baseline ECG

Complication of cardiac cath and other vascular procedures




What skin finding?

Arterioembolism (cholesterol embolism) --> causes tissue/organ ischemia




Suspect in pt post vascular procedure w/renal failure, purple/painless mottling of skin (livedo reticularis), & GI symptoms

Med of choice for acute aortic dissection

Beta blocker

Peripheral artery disease/claudication increases the risk for what?

MI

Define malignant hypertension

Sever hypertension w/retinal hemorrhages, exudates & papilledema

When to perform carotid endarterectomy

> 70% stenosis

Systolic - diastolic abdominal/periumbilical bruit

Renal artery stenosis --> causes second degree hypertension

Alternative to IV penicillin

IV ceftrioxone

Sildenafil



1. For?



2. Contraindicated with?



3. Do what in hypertensive pt?

1. phosphodiesterase inhibitor for erectile dysfunction



2. Nitrates



3. When combined w/alpha-blocker (doxazosin, give drugs 4 hr apart to prevent hypotension

Niacin




1. Use




2. Side-effect




3. Mechanism of




4. Treatment

1. Treating lipid abnormalities




2. Cutaneous flushing & pruritis




3. Prostaglandin - induced vasodilation




4. Aspirin

Target cells seen in? (2)

Hemoglobinopathies




Chronic liver disease

Bilateral nasal discharge/obstruction and food tasting bland

Nasal Polyp

Ear pain in a nocturnal teeth grinder

Temporomandibular Joint Dysfunction

Muffled voice + uvula deviation




Treatment?

Peritonsillar abscess



Peritonsillar aspiration + IV antibiotics



Early onset hypertension & bilateral abdominal masses




1. Diagnose how




2. Treatment

Poly cystic Kidney Disease




1. Ultrasound




2. ACE Inhibitor

Side effect of loop diuretics

Ototoxicity

Decreased/normal pulmonary capillary wedge pressure


Decreased systemic vascular resistance


Increased CO, increased mixed venous O2 saturation

Septic/distributive shock

Hypovolemic shock


R. Atril Pressure


Pulmonary capillary wedge pressure


Cardiac output


SVR


Mixed venous O2 sat

Everything is decreased except SVR increase

What lab is a sensitive indicator of dehydration/hypovolemia

Increased BUN/creatinine

Dizziness, nausea, pallor, diaphoresis, abdominal pain, and general sense of warmth b4 syncope




1. Triggers




2. Diagnostic test

Neurocardiogenic (vasovagal) Syncope




1. Emotional distress, pain, prolonged standing




2. Tilt table but most are diagnosed clinically

Pt w/syncope and suspected structural heart disease




Next step?

Echo

Screening for abdominal aortic aneurysm

Smokers 65-75 y.o w/one-time abdominal ultrasound

Hypertensive Emergency


1. Define




2. Treatment?




3. Side effect?




4. Signs/symptoms of side effect

1. End organ failure (heart/kydney) from hypertension




2. Nitroprusside




3. Cyanide poisoning




4. AMS, seizure, coma, lactic acidosis

Hypertension definition




1. Primary intervention




2. Secondary intervention

> 140 mmHg systolic and/or > 90 mmHg diastolic




1. lifestyle modification - weight reduction




2. DASH diet - increased fruits/veggies, decrease low saturated/total fat

Likely DVT




Next step?

Ultrasonography




Start heperin if suspect PE but not for suspected DVT

Abdominal Aortic Aneurysms




1. Risk factors for rupture?




2. When to operate?

1. Size, rapid expansion/growth and smoking




2. resect if > 5.5cm, growing > 1cm/yr or causing symptoms

Hypertension causes what kind of heart failure?

Diastolic




Stiff ventricle --> filling (diastolic) defect --> L. atrial dilation --> a. fib

Define




1. Hypertensive urgency




2. Hypertensive emergency

1. Severe hypertension (>180/120) w/no symptoms of end - organ failure




2. Sever hypertension w/organ failure

Man who loses consciousness immediately after urination or a coughing fit

Situational syncope

Exertional Heat Stroke




1. Define


2. Complications


3. Treatment

1. Temp > 40 C (104 F) w/encephalopathy




2. Multi-organ dysfunction




3. Rapid cooling (ice-water)

Orthostatic Hypotension




1. Definition




2. Causes of aging

1. 20mmHG decrease systolically or 10mmHg decrease diastolically on standing




2. Decreased baroreceptor sensitivity

Muscle weakness, recurrent nephrolithiasis, neuropsychiatric symptoms, and hypercalcemia




Most common cause?

stones, groans, moans & psychiatric overtones = Primary Hyperparathyroidism




- Usually 2/2 parathyroid adenoma

Howell-jolly bodies seen in?

Pts w/out a spleen

Post MI: leg is cold/mottled




Next step?

Acute limb ischemia




Echo to look for L. ventricular thrombus

Bilateral pitting edema, varicose veins and venous ulcer




Treatment?

Venous Insufficiency




Leg elevation, compression stockings and exercise

Imaging choice for aortic dissection

CT but transesophageal echo if abnormal creatinine (kidney disease)

Management of ST-segment elevation myocardial infarction (STEMI)




1. When to cath?


2. What to do if can not cath?


3. Drugs?

1. Perform percutaneous coronary intervention (PCI) w/in 12 hrs of symptom onset or 90 min of medical contact




2. Fibrinolytics if w/in 12 hrs of symptom onset




3. oxygen, aspirin, plt P2Y12 receptor blocker (clopidogrel, ticagrelor), nitroglycerin, beta blocker, and anti-coagulant (heparin)

Amiodarone




For?


Side effects?

Anti-arrhythmic --> for ventricular arrhythmias, rhythm control and ventricular systolic dysfunction




hypo/hyperthyroidism


hepatotoxicity


Bradycardia/heart block


lung/neuro/eye disturbances (corneal deposits)


pulmonary fibrosis


blue-gray skin

Nocturnal, brief (15-20 min) pain in a young woman




1. Associated w/what other


2. Greatest risk factor?


3. Treatment?

Angina (prinzmental/varient)




1. Raynauds + migraine headaches


2. smoking


3. Ca2+ channel blockers, nitrates

Normal JVP

< 3cm above sternal angle

Dressler's syndrome




Treatment?

Post-mycardial pericarditus 1-6 wks after MI




NSAIDS (aspirin)

Side effects of hydrochlorothiazide




1. Metabolic side effects


2. Electrolyte abnormalities


3. Activates what disease?

Hyperglycemia, increased LDL, increased triglycerides




2. Hypercalcemia, hyponatremia and hypokalemia




3. Gout

5 P's after an MI




1. Define


2. Next step


3. Definitive treatment

Limb ischemia (artery occlusion)


Pain, pallor, pulselessness, parethesia, poilcilothermea




Heparin




Embolectomy (surgery)


Irregularly irregular ECG, absent p-wave

Treatment?


Irregularly irregular ECG, absent p-wave




Treatment?

A-fib




If stable --> B-blocker or Ca2+ channel inhibitor


If unstable --> cardioversion --> AMS, hypotension, etc

ECG findings for preicarditus




Specific ECG finding?

Diffuse ST elevations




PR depression

Headache, increased BP, renal bruit




1. Cause in young vs old pt




2. Treatment

Renal artery stenosis




1. young = fibromuscular dysplasia


old = atherosclerosis




2. Angioplasty w/stent placement

Scleroderma Renal Crisis




What blood cells?

Acute Renal Failure + Hypertension




Schistocytes

Imaging of choice for diagnosis and follow-up of an abdominal aneurysm

Ultrasound

Hypertrophic Cardiomyopathy




1. Symptoms


2. Inheritance


3. Mechanism


4. Treatment

1. Episodes of syncope, systolic (harsh crescendo decrescendo) murmur along left sternal boarder, sudden death.


2. Autosomal dominant


3. Myocardial hypertrophy causes diastolic heart failure asymmetrical septal hypertrophy


4. B-blockers (prolongs diastole)


Cardiac acting Ca2+ channel blocker (diltiazem)

Cause of:




1. Ascending aortic aneurysms




2. Descending aortic aneurysms

1. Cystic medial necrosis (aging)


Connective tissue diseases (Marfans, Ehlers-Danlos)




2. Atherosclerosis

Heparin-induced thrombocytopenia




1. What drug?


2. Signs/symptoms?


3. Type I vs Type II

1. Unfractionated heparin




2. Decreased plt more than 50%, thrombosis, thrombocytopenia




3. Type I - non-immune direct effect of heparin on plts usually on day 2. No need to stop




Type II - antibodies against PF4, on days 5-10, Stop med

Suspect Hypertension second degree to kidney disease when? (4)

1. Diffuse atherosclerosis


2. Asymmetrical kidney size


3. Recurrent flash pulmonary edema


4. Increase serum creatinine > 30% after starting ACE inhibitor

Single photon emission CT scan




1. Used for?




2. Treatment?

1. Evaluating CAD. Decreased perfusion = CAD, if inducible, then ischemic coronary artery disease




2. Anti-platelet (aspirin), B-blockers and lifestyle modifications to prevent MI


Ca2+ channel blockers and nitrates are used if pt has hypotension or bradycardia

Treatment for acute decompensated heart failure (3)

oxygent, diuretics, nitrates

Treatment for A-fib in Wolff-Parkinson-White

Unstable --> cardioversion




Stable --> rhythm control: procainamide

Bradycardia, hypotension, wheezing, hypoglycemia, delirium, seizures and cardiogenic shock




1. Treatment - 1st & 2nd step

B-blocker overdose




Atropine + IV fluids




IV glucagon

Malignant otitis externa in old diabetic patient




1. Signs/sumptoms


2. Organism


3. Complications


4. Treatment

1. Ear discharge granulations


2. Pseudomonas


3. Osteomyelitis of skull or nerve damage


4. Systemic antibiotics (ciprofloxacin)

Most common benign primary cardiac tumor




1. Location


2. Symptoms


3. Complications

Myxoma




1. Usually L. atrium


2. constitutional symptoms (fever, wt loss, etc)


3. Systemic embolization

Peripheral artery disease (claudication)



1. Treatments

Aspirin + statin


Graded Exercise

Treatment for pulmonary hypertension 2/2 left heart disease

Diuretics and ACE inhibitor

Systolic hypertension w/left ventricular hypertrophy in elderly




1. Cause


2. Treatment

Isolated systolic hypertension (ISH)




1. Decreased elasticity aterial wall (arteries become rigit) as pt ages causing widened pulse pressure (increased systolic w/normal diastolic)




2. Thiazide, ACE inhibitor, or Ca2+ channel blocker

3 uses for N-acetyl cysteine

1. Dissolution of mucus


2. protection from contrast-induced renal failure


3. Acetaminophen overdose

Vertigo, earfullness, tinnitus, hearing loss




Treatment?

Meniere's disease (inner ear)




Diet modifications: no drugs/alcohol and sodium restriction