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18 Cards in this Set
- Front
- Back
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CAV-2 vaccine protects dog against two specific illnesses? |
Infectious canine hepatitis Canine infectious respiratory disease |
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Canine adenovirus-2 Infectious canine hepatitis |
Caused by canine adenovirus-1what |
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What was the problem with using CAV-1 vaccine? |
Ocular disease Dog would shed the virus following vaccination. Cause blue eye |
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CAV-2 |
Gives cross protection from CAV-1 and CAV-2 |
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Susceptible species to the virus? |
Bears Wild dogs Other Wild animals Low vaccines area |
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The virus is more severe in? |
Puppies Young dogs |
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Transmission? |
Urine Feces Saliva Ingestion of infection bodily fluids |
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How does the virus spread / pathways? |
1. Multiplies in the tonsils/ nearby immune tissues 2. Accesses the circulation and targets the endothelium of the vasculature ( lining cells blood vessels) 3. Affects organs: liver (hepatitis disease) can infect kidneys 4. Forms immune complexes Antibody- antigen complexes - failure to remove immune complexes can lead to autoimmune disease. |
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Clinical signs |
Early signs: mild signs Fever/ can be biphasic Lethargy Anorexia Tonsillitis Ocular and nasal discharge |
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Clinical signs later signs |
Abdominal pain: do to liver disease Hemorrhage: caused by liver disease and damaged to the vascular endothelium Neurologic signs: possible |
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Liver plays a huge role in? |
Clotting factors! |
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Post recover |
One or two weeks later Because of the immune complexes: they form corneal edema takes on water and anterior uveitis -blue eye Kidney damage |
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Diagnosis |
Lethargy- tonsillitis- abdominal pain- hemorrhage PCR ( finding the DNA of the virus), ELISA testing (snap test) Necropsy Liver changes and evidence of hemorrhage PCR, IFA, Virus isolation |
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Treatment |
*no magic pill for the virus* 1. Supportive care 2. IV fluids 3. Transfusions in severe cases- bleeding in places you shouldn’t and the dogs doesn’t have the clotting factors 4. Antibiotics: treatment and prevention of getting secondary bacterial infections 5. Antivirals: perhaps, I am sure it’s been tried 6. Nutrition: parenteral, they don’t feel like eating 7. Antipyretic: anti fever meds 8. Antiemetic meds 9. Analgesics meds 10. Ocular discharge= pain management/ eyes are painful |
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Prognosis |
Depends on the severity of the disease Hemorrhagic signs: prognosis is poorer, lost all your clotting factors? Younger animals Liver problems that won’t improve= not good Mortality rate is 20% |
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Prevention |
Animals that has had the virus in the past can shed the virus in their urine for 6 months. Especially with puppies- susceptible and don’t recover as well Vaccinate |
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Vaccination |
Modified live - preferred Killed |
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Vaccination protocol? |
Combination with DA2PPV 6-8 weeks 3-4 weeks after that Until 16 weeks Until 20 weeks for some (for distemper and parvovirus but CAV-2 is in the combo vaccine) Booster. A year later Revaccinate every 3 years or titers check |
