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233 Cards in this Set

  • Front
  • Back

in humans metbolizing cells perform funcitons such as

digestion


muscle movement


hormone production


two types of energy in biology

potential energy


kinetic energy

potential energy examples

chemical energy (stored in bonds)


concentration gradient across a membrane

kinetic energy examples

light


sound


movement of atoms and molecules


muscle contraction

energy allows cells to

do work

physicists define energy as

the ability to do work


-move matter

the total amount of energy in any object is

the sum of potential and kinetic energy

potential energy

stored energy available to do work

kinetic energy

energy being used to do work

forms of energy are emasured in units called

calories

one calories is the

amount of energy required to raise the temperature of 1 gram of water from 14.5c to 15.5 c

kilcalorie(kcal)

1000 calories

two physical laws that describe the energy conversions vital for life and those that occur in the nonliving world

-law of energy conservation


-all energy transformations are inefficient because every reaction loses some energy to the surroundings as heat

law of energy conservation

-states that energy can not be created or destryoed


-energy an be converted to other forms


most important energy transformation ins life are

photosynthesis and cellular respiration

in photosynthesis

plants and some microbes use carbon dioxide, water, and the kinetic enregy in sunlight to assemble glucose moleucles


-glucose (carb molecules) contain potential energy in their chemical bonds

in cellular respiration

glucose molecules change back to carbon diozide and water, liberating the energy necessary to power life


- cells trnaslate the potential energy in glucose into the kinetic energy of molecular motion and use that burst of kinetic energy to do work

second physical law of energy

all energy transformation are inefficient because every rection loses some energy to the surroundings as heat

law that states all energy transformations are inefficient

losing energy to heat is inevitable

entropy is a

measure of the heat energy loss

the more disordered a system is

the higher its entropy

organisms can increase in compexity as long as

somthing else decreases in complexity by a greater amount

what are some examples of the work of a cell

plant cell assemblesglucose molecules into long cellulose fibers


moves ions across its membranes


give examples of potential and kinetic energy in your body

potential= energy stored in bonds


kinetic energy= muscle contraction

what are some energy conversions that occur in cells

photosynthes and cellular respiration

why does the amount of entropy in the universe always increase

because organims are highly organized because the sun is constantly supplying energy to earth


but


entropy of the universe as a whole is always increasing

networks of chemical reactions

sustain life

metabolism

encompasses chemical reasctions in cells that build new molecules and that break down exisiting ones

each metabolism reaction

reaaranges atoms into new compounds


- either abosrbs or releases energy


chemical reactions

absorb or release energy

reactions that build complex molecules from simpler components typically require

energy input

if a reaction releases energy the ______ contain less energy than the _______

products , reactants

chemical reactions that release energy

break large complex molecules into their smaller simpler components


-cellular respiration is an example (glucose, to co2 and h20)

most energy transformations in organisms occur in

oxidation reduction reactions

oxidation reduction reactions

transfer energized electrons form one molecule to another

oxidation

the loss of electrons from a molecule, atom, or ion

oxidation reaction examples

glucose to co2 and h20 , rlease energy as they degrade complex molecules into simpler products

reduction

gain of electrons plus any energy contained in the elctrons


- require a net input of energy

oxidations and reductions occur simultaneously because

electrons removed from one molecule during oxidation join another molecule and reduce it


- f one molecule is reduced (gains molecules) then another must be oxidized (loses electrons)

reactions that require energy

bind small molecules with adding energy

reactions that release energy

divide bigger molecules with taking out energy

groups of electron carrying proteins align in

membranes

electron trnasport chain

each protein accpets n electron from the molecule before it and donates the electro to the next in line


-first reduced then oxidized


-energy is released as each step


this plays a key role in both photosynthesis and respiration

electron transport chian

what is metabolism on a cellular level

metabolism encompasses chemical reactions that build new molecules and break down old ones

which reactions require energy input and which release energy

reactions that bind together to make complex molecules typicallly require energy input


reactions that break complex molecule apart release energy

what are oxidation and reductino and why are they always linked

oxidation is the release of electrons


reduction is the gain of electrons


alwasy linked because electrons are removed from one molecule during oxidation then join another molecule and reduce it

what is an electron transport chain

electron donor transfers an electron to the first protein and continues to get passed on until a final electron acceptor

atp is

cellular energy currency

covalent bonds of adenosine triphosphate

commonly known as atp


- temporarily store energy released in chemical reactions

atp

type of nucleotide


based adenine, five carbon sugar ribose, and three phosphate groups


-the three phosphates place negative charges very close to one another which makes it unstable so it releases energy when the covlanet bond between the phosphate breaks

in eukarotic cells this creates most of the cells atps

mitochondria

mitochondrion uses the potential energy in the bonds of one glucose molecule to generate

dozens of atp molecules in cellular respiration

the cell that contain the most mitochondria

the most energy hungry cells


-muscles and brain

when a cell requires energy for a chemical reaction it spends atp by

removing the endmost phophate group

adenosine diphosphate

the product of hydrolysis reaction (removing endmost phosphate group to use atp)

energy can be temporarily stored by adding a

phosphate to adp, forming atop and water

this is a nucleotide consisting of adenine, ribose, and three phosphate groups

atp

this drives the reactions that require energy input


-those that do work or synthesize new molecule

atp hydrolysis

cells use atp hydrolysis, a reaction that releases energy, to fuel reactions that

rewuire energy input

cell generate s atp in other reactions

such as those that break down food

coupled reactions

cell uses atp as an energy source by transferring its phosphate group to another molecule


- this transfer may either energize the target molecule making it more likely to bond with other molecules


or


- added phosphate group may change the shape of the target molecule

jobs that require atp include

tranporting substances across cell membranes


movin chromosomes during cell division


synthisizing the large molecules that make up cells


cell can use respiration to

rebuild its pool of atp

atp represents

short term energy storage

when atp donates a phosphate group to a molecule the recipient may

1. be more likely to bond


or


2. change its shape in a useful way

this makes atp too unstable for long term storage

high energy phosphate bonds

how does atp hydrolysis supply energy for cellular functions

atp hydrolysis liberates a phosphate and releases energy which fuels reactions that require energy input

descrive the relationship between enregy requiring reactions, atp hydrolysis and cellular respiration

cellular repiration creates atp, atp hydrolysis releases energy which fuels energy requiring reactions

these speed biochemical reactions

enzymes

an organic molecule that catalyzes (speeds) a chemical reaction without being consumed

enzyme

most enzymes are

proteins


but some are made of rna

many of cells organelles includeing mitochondria, chloroplasts, lysosomes, and peroxisomes are

speicalized sacs of enzymes

a few jobs of enzymes

copy dna


build proteis


digest food


recycle a cells worn out parts


catalyze oxidation reduction reaction

enzymes speed reactions by lowering

the activatio energy

activation energy

the amount of energy required to start a reaction

the ______ brings reactants (substrates) into contact with one another so that less energy is required for the reaction to start

enzymes

the lower the activation energy the

faster the reaction can proceed

most enzymes can catalze only

specific one or few chemical reactions

active site

the region to which the substrates bind


-the shape of the active site etermines what enzymes can catalyze

reactions do/do not consume or alter the enzyme

do not

substrates fit into enzymes active sites like

puzzle pieces

negative feedback / feedback inhibition

product of a reaction inhibits the enzyme that control its formation

negative feedbacks two general ways of preventing too much of the reaction product from accumulatin

1. noncompetitive inhibition


2. competitive inhibition

noncompetitive inhibition

product molecule binds to the enzymes at a location other than the active site

this action alters the enzymes shape so that it can no longer bind the substrate

noncompetitive inhibition

competitive inhibition

the reaction product binds to enzymes active site which prevents it from binding substrates


- competitive because the product competes with the substrate to occupy the active site

an enzyme cna become denatured and stop working if

ph changes


salt concentration becomes too high or low


temperature is too hot


pharmaceutical drugs


some poisons

what do enzymes do in cells

copy rna, build proteins, digest food, recycle a cells worn out parts, catalyze oxidation reduction reactions

how does an enzyme lower a reactions activation energy

an enzyme brings reactants or substrates into contact with one another so that less energy is required for the reaction to start

what is the role of negative feedback in enzyme production

when the product of a reaction inhibits the enzyme that control its formation, shape, and functionality


-change shape of protein or prevents the substrate from entering

this changes the shape of the protein

noncompetitive inhibitor

this physically blocks the enzymes active site preventing the substrate from entering

competitive inhibitor

conditions that influence enzyme activity

ph


salt concentration


temperature


pharmaceutical drugs


poison

potential energy is stored in

chemical

potential energy is highest at

top of mountain


highest point of bulb droping

kinetic energy is highest

while going down hill


while bulb is falling through space

entropy is highest at

the drop or breaking of light bulb

osmosis is defined as

water molecules diffusing through a membrane from a high concentration of water to a lesser concentration of water

water molecules being diffused across a membrane from a high water concentration to a low water concentration is known as

osmosis

these types of molecules will diffuse through the cell membrane the easiest

small and nonpolar molecules

large and polar molecules have a

hard time diffusing across a membrane

hypotonic solution has

more water to solutes

hypertonic solution has

more solutes to water

red blood cell in a hypertonic solution will

shirnk

2% acid solution is _______ to a 15% acid solution

hypotonic

a 13% nickel solution is _______ to a 8% nickel solution

hypertonic

water moves in and out of the cell at equal rates in this type of solution

isotonic

this type of energy is stored in chemicals

potential energy

relations between :


active transport


ATP


energy


concentration gradients

active transport uses ATP to form concentration gradients which is stores potential energy

processes that decrease the amount of potential energy stored across a membrane

facilitated diffusion


simple diffusion

=different ways movement across a membrane occurs

active transport


passive transport


transport using vesicles

active transport

net movement is against concentration gradient; requires transport protein and energy input, often from ATP


passive transport

new movment is down concentration gradient


does not require energy input

simple diffusion

substance moves across membrane w/o assistance of transport proteins


-goes from area of high concentration to area of low concentration

osmosis

water diffuses across a selectively permeable membrane from high concentration of water to low concentration of water

facilitated diffusion

substance moves across a membrane with assistance of transport proteins


-from area of high concentation to area of low concentration

this type of diffusion requires transport proteins

facilitated difusion

this type of transport across a membrane requires energy; typically from ATP

active transport

transport using vesicles

vesicle carries molecules into or out of a cell

endocytosis

membrane engulfs substance and draws it into cell

exocytosis

vesicle fuses with cell membrane releasing substances outside of cell

endo

inward engulf

exo

outward

negative feedback/ feedback inhibition

a way to regulate a metabolic pathway


- the product of a reaction inhiits the enzyme that controls its formation

two types of negative feedback

noncompetitive inhibition


competitive inhibition

noncompetitive inhibition

a product molecule or inhibitor binds to the enzyme at a location other than the active site whch than alters the enzymes shape so that it can no longer bind the substrate

membrane is

selectively permeable


does not like polar or large molecules

interior of a cel is

chemically different from the outside

the inside of each organelle in a eukaryotic cell may be

chemically quite different from the solution in the rest of the cell

concentration gradient

solute is more concentrated in one region than in a neighboring region

concenration gradient

dissipates uness energy is expended to maintain it

random molecular motion

alys increases the amount of entropy

all forms of transport across membranes involve

gradients

all forms of passive transport involve

diffusion

diffusion

the spontaneous movement of a substance from a region where it is more concentrated to a region where it is less concentrated

why does diffusion not require energy input

because it represents the dissipation of a chemical gradient and the loss of potential energy

diffusion occurs because

all substances have kinetic energy so they are in constant random motion

diffusion appears to stop

but the molecules do not stop moving, travel randomly at same rate so at equilibrum the concentration remains equal throuhout the solution

simple diffsuion

passive transport


moves down its concentration gradient


does not get aid of a transport protein

substances enter or leave cells by simple diffusion only if

they can pass freely through the membrane


lipids and small, nonpolar molecules such as oxygen and carbon dioxide diffuse

easily across the hydrophiv portion of a biological membrane

cells maintain gradients

- by continually consuming the substances as they diffuse in


-by producing more of the substances that diffuse out

diffusion of water across a selectively permeable membrane

osmosis

isotonic

the solute concentration inside the cell is he same as that of the outside

if the solution is hypotonic to the cell

the external solute concentration is lower than it is inside the cell

hypo

under

hyper

over

in a hypertonic enviornment

a cell loses water shrivels and may even die

the net direction of water movement is from the

hypotonic solution to the hypertonic one

turgot pressure

the resulting forced of water against the cell wall


lost turgor pressure

limp wilted plant

helps keep plants erect

turgor pressure

ions and polar molecules cannot freely cross the hydrophbic part of the phospholipid bilayer

so transport proteins form pores that help these solutes cross

form of passive transport where membrance protein assists the movement of a polar solute along its concentration gradient and does not need energy because it is going down the concentration gradient

facilitated diffusion

bacteria, plants, and animals use

membrane proteins called aquaporins to increase the rate of water flow

this type of transport requires energy

active transport

in this type of transport -


cell uses a transport protein to move a substance against its concentration gradient


goes from where it is less concentrated to where it is more concentrated

active transport

cells must contain high conenctrations of ____, and low concentrations of _______

potassium, sodium

one active transport system in the membranes of most animal cells is a proein called

sodium-potassium pump


-uses atp as an energy source to expel three Na+ for every two K+ it admits

endocytosis and exocytosis

use vesicles to transport substances

vesicles used to transport substances

are small sacs that can pinch off of or fuse with a cell membrane

endocytosis

allows a cell to engulf fluids and large molecules and bring them into the cell


-molecules push on cell membrane and the indentation then becomes a indepenedant bubble of membrane that encloses on itself

two main forms of endocytosis are

pinocytosis and phagocytosis

pincytosis

cell engulfs small amounts of fluids and dissolved substances

phagocystosis

cell captures and engulfs large particles such as debris or even another cell


-veiscle then fuses with lysosome where dyrolytic enzymes dismantle the cargo

large particles enter a cell by

endocytosis

white blood cells doing their job is an example of

endocytosis

exocytosis

uses vesicles to transport fluids and large prticles out of cell

in exocytosis, the ______ produces vesicles filled with substances to be secreted

golgi appartaus

vesicle moves to the cell membrane and joins with it releasing the substance outside the membrane

exocytosis

what is diffusion

the spontaneous movement of substances from where there is a high concentration to a low concentration

what type of substances diffuse freely across a membrane?

-polar, small, and lipid substances

how do differing concentrations of solutes in neighboring solutions drive osmosis?

the solution differences determine whether the relationship is isotonic, hypotonic, or hypertonic

why does it cost energy to maintain a concnetration gradient?

because entropy is always increasing, you must put energy to reverse these effects

distinguish between simple diffusion, facilitated diffsuion, and active transport

simple diffusion= no protein aid, no energy input, passive transport, polar small molecules pass through easily, moves down concentration gradient


facilitated diffusion= has protein aid, no energy input, passive transport, moves down concentration gradient


active transport= requires energy, moves up conenctration gradient ( goes from low concentration to high concentration), requires atp ususally

all cells

capture and use energy

potential energy

stored energy

kinetic energy

is action

energy is measured in units called calories

one food calories is 1000 calories or 1kcal

energy is converted from one form to another

energy cannot be created or destroyed but only converted to other forms

every reaction inreases

entropy and loses energy as heat

the sum of the chemical reactions in a cell

metabolism

chemical reactions absorb or release energy

true

in reactions that require energy input

the products have more energy than the reactants

in reactions that release energy

the products have less energy then the reactants

linked oxidation and reduction reactions form

electron transport chains

many energy transformations in organisms occur via

redox reactions

the loss of electrons

oxidation

gain of electrons

reduction

in photosynthesis and respiration, proteins shuttle electrons along

electron transport chains

cellular energy currency

atp

_______ stores energy in its high energy phosphate bonds.


cellular respiration generates this

ATP

cells use the energy released in ____________ to drive other reactions

ATP hydrolysis

this represents short term energy storage

ATP

cells store energy as

fats and carbohydrates

the faulty membrane protein that causes cystic fibrosis may help protect against

choler

building proteins _______ energy

requires

ATP hydrolysis _________ energy

releases

proteins contribution to the function of an electron transport chain

they become oxidized and reduced

where in a molecule of ATP is the stored energy that is used by the cell

in the covalent bonds between the phosphate groups

the role of an enzyme in a cell

to speed up chemical reactions

the active site is unaable to bind substrate

in noncompetitive inhibition

the movement of water molecules during osmosis is due to

diffusion

ions and polar molecules need __________ diffusion across membrane

facilitated diffusion

substances that diffuse freely across a membrane

nonpolar, small molecules and lipids

concentration gradient is an example of

potential energy

some people claim that the high degree of organization defies the physical law that says entropy always increases. what makes this statement false?

this statement is only valid if organisms are closed


and


organisms can increase in complexity as long as something else decreases in complexity by a greater amount

atp is energy currency

you spend ATP to fuel chemical reactions

how do enzymes speed chemical reactions

enzymes copy dna, build proteins, digest food, recycle a cells worn out parts, and catalyze oxidation reduction reactions


- they bind to substrates which then releases the production

fat digesting enzymes are not able to digest a artificial fat because

artifical fat has a different shape than that of a normal fat so the digestive enzyme would not recognize the artificial fat

chemical structure of ATP

3 phosphate groups, ribose, adenine


nucleotide


how does atp hydrolysis supply energy for cellular function

hydrolysis of atp breaks the bond of atps endmost phosphate group, releasing energy

atp that is produced in cellular respiration can be hydrolyzed to release energy that can be used to drive endergonic reactions (reactions that require energy input)

atp that is produced in cellular respiration can be hydrolyzed to release energy that can be used to drive endergonic reactions (reactions that require energy input)

these speed up chemical reactions (catalyze) without being consumed in the process

enzymes

how do enzymes lower a reactions activation energy

enzymes bring reactants into contact of eachother so that less energy is required to start the reaction

conditions that effect an enzymes activity

pH, temperature, and salt concentration

It costs energy for a cell to maintain a concentration gradient because

it must move substances against diffusion, which tends to allow gradients to dissipate

endocytosis and exocytosis function by

binding lipid bilayer that surrounds vesicles with lipid bilayer of the cell membrane

endergonic reactions

require energy

exergonic reactions

release energy

Enzymes speed chemical reactions by

lowering the energy of activation, the amount of energy required to start a reaction.

Why does poking a hole in a cell’s membrane kill the cell?

cell membrane holds together the cells internal enviornment


-a hole in the cell membrane would allow organelles and dissolved chemicals to leave, and the cell would die

diffusion is efficient only over

small distances and as long as all parts of the cells interior are close to the surface of the cell

the chemical bond energy in ATP is a form of __________ energy

potentinal energy

example of entropy

heat energy being lost at each step of energy conversion

an example of kinetic energy

sunlight

sunlight creates photosynthesis which binds with oxygen to create glucose which then goes to cellular respiration which transforms to potential energy or carbon dioxide and water and then repeats the cycle

cycle of energy conversion

when products contain more energy than reactants

it is a reaction that requires energy input or endergonic reaction

when reactants contain more energy than products

it is a reaction that releases energy or exergonic reaction

an example of a energy requiring reaction

photosynthesis

an example of an energy releasing reaction

cellular respiration

example of potential energy

glucose