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61 Cards in this Set

  • Front
  • Back

What is an arbovirus? Example?

Arthropod-borne virus. Zika.

Are Asian and African Zika lineages similar or different?

Different

What was noticed of the Lahore & Leeds/Bradford populations?


What caused this?


What is this an example of?

High rates of microencephaly.


Cousin-cousin marriages.


Inbreeding depression.

What is antigenic drift?

Mutations within the genes that code for antigens in viruses. Results in constantly-changing surface antigens.

What is antigenic shift?

Recombinations between different strains of virus. Results in much greater changes than antigenic drift.

In H1N1, what do the H and N refer to?

The Haemagglutinin and Neuraminidase antigens that differ between strains.

Why are Type B flus generally less mutable than Type A flus?

Less likely to cross species.

In phylogenetic graphs of the flu, what country/region forms the main trunk that carries the flu from year to year?

Asia

2 reasons that Asia is flu "hub"?

1. Increased animal-human contact (agriculture)


2. High population density

2 theories about how Spanish flu started?

1. Military camps in close contact with agricultural settings (Kansas, Paris)


2. Originated in China. Chinese workers were being hired to dig trenches.

What term/phenomenon describes why the mortality rate of the Spanish flu was so high in youth (x20 mortality rate)?

Cytokine storm - immune system blows up

What strain of flu was the Spanish flu?

H1N1

Can the bird flu be transmitted from human-to-human yet?

No

What strain of flu was the avian flu?

H5N1

In what season did H1N1 begin in 2009? Is this expected?

It began in the Spring. This is expected of pandemic flus.

What happened to the seasonal flu in 2009 following H1N1?

It was virtually eliminated. Did people get the vaccine or start practicing better hygiene...?

Do pandemic flus come in waves/pulses or are they steady?

Pulses.

Was Darwin the first to study evolution?

No. His grandfather and Lamarck did too.

What was Lamarck famous for proposing?

Lamarck proposed that the physical attributes you acquired throughout your life could be passed onto your offspring. (He was "the one who got it wrong").

Who initially proposed Uniformitarianism and who expanded upon it?

Hutton proposed it.


Lyell expanded upon it.

Explain the theory of Uniformitarianism.

Changes in the Earth's crust during geological history have resulted from the action of continuous and uniform processes. This forces continue to shape the Earth today.

What did Malthus notice?

The tendency for populations to grow exponentially. But since resources do not grow exponentially as well, Malthus predicted catastrophe.

What term best describes the following: the environment contains finite resources, limitingpopulation size and creating competition.

The struggle for existence

Many people associate Darwin with finches. But what animal was he most interested in?

Mockingbirds

What did the mockingbirds show Darwin?

Mockingbirds were different island to island. Suggested to Darwin that each island population had been colonized by a small group from the mainland population and adapted to their environment. --> DESCENT WITH MODIFICATION

What are the three requirements of natural selection (Darwin's big idea)?

1. Variation among individuals


2. Heritability


3. Differential survival and reproduction

Who was writing about the same ideas of Darwin at the same time?

Wallace

What is the ancestor of cabbage, kale, cauliflower, broccoli, etc.

Brassica oleracea

Who studied Soapberry bugs?

Scott Carroll

What did Carroll's soapberry bug experiment ultimately prove?

The beak length of soapberry bugs was not caused by phenotypic plasticity.

What are guppy predators like on either side of the Trinidadian waterfalls?

Above waterfall = predators that only prey on small guppies (low predation)


Below waterfall = fierce predators that prey on all guppies (high predation)

What are male guppy characteristics above/below waterfalls?

Above: Larger, colourful


Below: Smaller, duller

Who conducted the guppy predation experiments?

John Endler

What did John Endler's experiments suggest?

That characteristics of the guppies were not random - they had developed overtime due to predation regimes.

Why is it believed that guppies are smaller and duller in high predation environments?

Smaller = mature faster (can reproduce sooner since they don't know how long they will live)


Duller = less conspicuous to both predators and females (can sneak up on them and mate)

What is a homologous structure? Give an example.

A structure that appears in different animals indicating a common ancestor. Ex: Mammalian forelimb.

What is an analogous structure? Give an example.

A structure that has the same function, but does not suggest descent from a common ancestor. Ex: Wings of insects vs. birds

What is convergence? Give an example.

When natural selection causes two species to adapt similar structures. Ex: Whales and whale sharks.

What is a vestigial structure? Give an example.

A structure that no longer serves a purpose. Ex: Wings on a kiwi. Hind-limbs on whales and snakes.Goosebumps on humans.

What are neutral loci and what do they indicate?

Neutral loci do not have a strong functional basis. Similarities in neutral loci indicate descent from a common ancestor.

What is a synapomorphy? Give an example.

A characteristic present in an ancestral species and shared exclusively by its descendants and no other animals. Ex: Feathers present in all modern birds.

What is phylogeny?

The inferred evolutionary relationships among various biological species.

What are HOX genes?

After the segments have formed, HOX genes determine the type of segment structures (i.e. legs, antennae, wings, etc.) that will grow from each segment. Thus, HOX proteins confer segmental identity but do not form the actual segments themselves.

What is parallelism?

When two species adapt in the same way in separate environments.

What is a pseudogene?

A section of a chromosome that is an imperfect copy of a functional gene. Provides evidence of DNA sequence that used to be functional in ancestor.

What are cladistic methods?

Grouping organisms by shared characteristics (synapomorphies).

What is a clade?

A group consisting of all descendants of a common ancestor bearing a certain characteristic.

What is genetic polymorphism?

When more than one allele exists at a given locus

If loci are governed by Mendelian rules, artificial selection will cause what kind of response?

Rapid, but bounded.

What is average heterozygosity?

An estimation of the proportion of loci in the genome that have two different alleles

Are mutations more likely to be hidden or unhidden from the forces of natural selection?

Hidden

What is the difference between how selection works in sexual vs. asexual populations?

Sexual - selection acts on pre-existing genetic variation (since mutations take a long time to build up)


Asexual - selection acts on mutations (since there is a large number of organisms reproducing very rapidly)

The ability of E. coli to metabolize citrate after a period of time in the lab is an example of what phenomenon?

A "key innovation" - a trait allowing the colonization of a new resource or habitat (as a result of many mutations "potentiating" this ability over time).

What is allelic richness?

The average number of alleles per locus

What is the "ultimate" source of variation?

Mutation

What is a "cline"?

A series of connected populations showing a continuous gradient of traits and genetics.

What are the consequences of an inversion?

1. Cross-over between chromosomes at that locus no longer possible.


2. Creates new order of genes. If two genes placed next to each other work well together (in a way that cannot be explained by additive effects alone) - a "supergene" is created. This is common in Drosophilus.

How is sex a double-edged sword?

Good - if you hold a "bad hand" or the environment is unpredictable


Bad - if you hold a "good hand" and the environment is stable

What two problems led to the Hardy-Weinberg principle?

1. Blending (why didn't intermediate traits sweep the entire population)


2. Dominance (why didn't all alleles become dominant)

What are the 5 required conditions for the Hardy-Weinberg principle to hold?

1. Random mating


2. Large population


3. No migration


4. No mutations


5. No natural selection


(Often does not occur in real life)



What are the two equations of the Hardy-Weinberg principle?

p + q = 1 (Gene frequency)


p^2 + 2pq + q^2 = 1 (Genotype frequency)