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44 Cards in this Set

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What are the different types of data?

Nominal = without order (gender, colour)


Ordinal = ordered (mild, mod, severe)


Discrete = whole numbers (number of cases)


Continuous = measurable value (height, weight)

What is categorical data

A type of qualitative data


Grouped into categories (gender, what surgery, adverse event)


Can have numerical component (ASA 1, 2, 3)

What is ordinal data

Type of categorical data which has a natural order


(pain score out of 0 to 10, mild-moderate-severe, ASA score)

What is numerical data

Quantitative data


- discrete: whole numbers (respiratory rate, number of MIs)


- continuous: numbers can assume any value (weight: 33.55kg)

Define mean, mode and median

Mean is the average (sum of all values divided by total number of values)



Mode is the most common value



Median is the middle value in a set of values

What is variance?

How close each individual observation clusters about the mean

What is the mathematical formula for standard deviation?

√variance

What is the standard error to the mean used for?

Measuring precision

What is the difference between accuracy and precision?

Define incidence and prevalence

What is type 1 and type 2 error

Type 1 error: incorrectly rejecting the true null hypothesis



Type 2 error: incorrectly accepting the false null hypothesis

What does the students t test do

Used to test the null hypothesis that there is no difference between the two means (can be used in sample sizes < 10)



*** Compares the means between 2 groups only

What does ANOVA do

Tests for significance between the means of 2 or more groups in a normal distribution

What is the use of Chi square

Tests whether there will be a difference in frequency of categorical data between 2 or more groups

What is the main feature of fishers exact test

Another method to analyse categorical data - calculate CI for RR or OR

What are the tests (in a decision tree) for comparing 2 or more independent groups?

What are the tests (decision tree) for comparing 2 or more paired groups

What test is best for categorical data with 2x2 small numbers (independent groups)

Fishers exact test

What test is used for categorical data with large numbers (independent groups)

Chi squared

What test is used for numerical data with 2 groups in a normal distribution


(independent groups)

Students t test

What test is used for two groups of non parametric data

Mann Whitney U test


Or


Wilcoxon rank sum test

What test is used for numerical data of three or more groups with normal distribution

ANOVA

What test is used for numerical data of two or more groups with non normal distribution


(independent groups)

kruskall wallis (ANOVA)

What test is used to compare paired categorical data for two groups

Mcnemar test

What test is used to compare paired categorical data for three or more groups

Cochran's q

What test is used to compare paired numerical data for two groups with normal distribution

Paired t test

What test is used to compare paired numerical data for two groups with non normal distribution

Wilcoxon signed ranks test

What test is used to compare paired numerical data for two or more groups with normal distribution

ANOVA

What test is used to compare paired numerical data for two or more groups with non normal distribution

Friedman's test

What is the formula for NNT

1/ARR

Formula for odds ratio

(odds of A) / (odds of b)


(A/C) / (B/D)

Define sensitivity and specificity

Sensitivity: TP/(TP+FN)



Specificity: TN/(TN+FP)

Define bias


What are the different types of bias

Recall bias: not recollecting events accurately



Observer bias: when not blinded



Recruitment bias: not randomising



Attrition bias: subjects being withdrawn



Publication bias: only publishing positive studies

What is intention to treat analysis

Including all participants assigned to an intervention group (even if it the intervention did not end up happening)

What is the difference between systematic reviews and meta analysis

What is the difference between odds ratio and relative risk

OR= (a/b) / (c/d)


In other words odds of 'a' divided by odds of 'c'



RR = a/(a+b) / c/(c+d)


Probability of 'a' divided by probability of 'c'

What are the components of the CONSORT checklist for evaluating an RCT

Check 'hint' for other parts

What is the central limit theorem?

The sampling distribution of any statistic will be normal or nearly normal if the sample size is large enough (n > 50)

What is the decision tree for using statistical tests for different types of data

What is the difference between probability and odds

Probability is the chance of an event occuring out of all possibilities.



Odds is the chance of the event occuring divided by the chance of the event not occuring

What is statistically / clinically significant

A = statistically and clinically significant


B = statistically significant but may not be clinically significant


C = is only statistically significant


D = is a poor study - can still potentially be statistically and clinically significant if CI can be reduced


E = not clinically or statistically significant

What are the EBM levels of evidence?

What are the 3 questions needed to be asked for critically appraising a study

What is hazard ratio