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20 Cards in this Set
- Front
- Back
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Antiviral drugs are used in the treatment of viral infections. There are two main serotypes of Herpes simplex virsus:
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- Herpes virus type 1 (HSV-1) - primarily causes oropharyngeal disease including eyes, vermillion border of lips, mouth & face
- Herpes virus type 2 (HSV-2) - primarily causes genital disease which is considered STD |
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after primary exposure, herpes simplex virus may persist in a latent state in the _________ until it is disturbed and then reactivated in adulthood
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trigeminal ganglion
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Primary herpes simplex virus is also known as
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primary herpetic gingivostomatitus
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In HSV-1, painful intraoral vesicles on the oral mucosa rapidly rupture to form small ulcers with __________. Lesions appear _______ hours after the first symptom and are self limiting and will resolve within _____ days. There is also generalized severe gingivitis present and ___________.
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- erythematous (red) halos
- 12-36 - 10-14 - cervical lymphadenopathy |
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Early treatment of HSV-1 with ____________ or __________ may significantly shorten the duration of all clinical manifestations and inefectivity of affected children
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- acyclovir (Zovirax)
- famciclovir (Famvir) |
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Recurrent HSV-1 occurs in individuals who previously had primary herpes and infection occurs around the mouth and is referred to as _________, a "cold sore" or "fever blister"
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Herpes labialis
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Systemic drugs used for herpes infections
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- Acyclovir
- famciclovir - valacyclovir |
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Topical drugs used for management of herpes labialis
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- acyclovir
- penciclovir - Docosanal (Abreva) OTC drug |
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Fungal infections are caused by
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molds or yeast
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The majority of heatlhy individuals have ________ species in the oropharyngeal area
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Candida
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There are ____ species of Candida that are reguarded as clinically important pathogens in human disease
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8
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_______ is partof the normal flora in the gastrointestinal and vaginal tracts
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Candida
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Fungal Infections (mycosis) are classified into three groups
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- Systemic mycosis (soft tissue, meningitis, UTIs)
- superficial mycosis (nails, skin, mucous membranes) - Subcutaneous mycosis (infections from contaminated soil) |
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Acute psuedomembranous candidiasis is also known as
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Thrush
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Thrush (acute psuedomembranous candidiasis) is caused by an overgrowth of
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Candidia albicans
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_________ is used in the treatment of thrush in infants and ______ in adults
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- Nystatin oral suspension
- fluconazole (diflucan) or ketoconazole (Nizoral) |
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__________ is a condition seen in patients with maxillary dentures, and when the denture is removed the palatal tissue appears as either small, localized asymptomatic red spots and the entire tissue is red
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Chronic Atrophic Candidiasis (Denture sore mouth)
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_________is as treatment for Candida suppression in HIV disease
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Prophylactic fluconazole
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Severe and extensive oropharyngeal candidiasis is treated with ____________ 100-200 mg orally twice a day
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Fluconazole (diflucan)
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Topical treatment for Chronic Atrophic Candidiasis (denture sore mouth) includes
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- Nystatin (mycostatin)
- Miconazole cream 2% - Ketoconazole cream 2% |
