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Hormones of Male Reproduction


Where are they being made? What’s their target cell? What is the end result?

Embryo is performed and grows/enlarges during development
Theory accepted until 19th century

What is epigenesis?

-man arises from The successor of differentiation of a formless and being


-embryo is organized from the mother’s menstrual blood after being acted on by semen

What do the Wolffian (mesonephric) ducts develop into?

Epididymis, ductus deferens, seminal vesicle, urethra

E, DD, SV, U

What do Müllerian ducts develop into?

Oviduct, uterus, cranial (upper) vagina

O, U, CV

What gene drives the gonads to become testes? What chromosome is it located on?

The Sex-determining Region of the Y chromosome

SRY

Does a female have the SRY gene?

No

If there is Sertoli cells or MIS?

Müllerian ducts develop

If there is no Leydig cells or testosterone?

Wolffian ducts regress

What is freemartin?

Abnormal embryogenesis of the female reproductive tract

How does freemartin happen?

Heifer born twin to bull -> share a common blood supply from the placenta in utero -> exposed to same hormones -> inhibited growth of Müllerian ducts -> ovaries fail to grow and produce estrogen -> genetic female behaves as bull

What are the major functions of the ovaries?

Oogenesis, folliculogenesis, estrogen and progesterone production

What are the major functions of the oviduct?

Site of fertilization


Transport of oocyte and sperm

What are the major functions of the uterus?

Fetal development, control of cyclicity and luteolysis, sperm transport

Why are the major functions of the cervix?

Protects sterile uterine environment, passageway for sperm and fetus

What are the major functions of the vagina?

Female organ of copulation

What are the major functions of the vulva?

External genitalia


Protection for vagina from outside environment

Hormones of Female Reproduction



where are they being produced? what are their target cells? what is the elicited response?

ovaries; granulosa cells; induces growth of follicles in ovary by binding FSH-receptors on granulosa cells

oogenesis




when is meiosis arrested? when does it resume? are females born with all potential gametes?

stops at prophase I; puberty; yes

Granulosa cells

line the antrum of pre-ovulatory follicle, have FSH receptors with primary action of follicular development and estrogen synthesis

theca cells

have LH receptors -> stimulation of ovulation, formation of CL, progesterone secretion (CL)

corpus luteum

large “yellow bodies” that produce progesterone, formed from granulosa and thecal cells after ovulation

corpus albicans

white, scar-like structure that represents degenerating CL, increasing connective tissue, decreasing secretory tissue

What follicle is ovulated?

Pre-ovulatory/dominant follicle

Key differences between female avian reproductive tract and mammals tract

Offspring development doesn’t occur in the body; only left ovary is functional; don’t form CL; have infundibulum, stigma, magnum, and isthmus, uterus also known as shell gland; no cervix; has cloaca

Avian ovary

Contains yolk, has stigma (where ovulation occurs)

Avian infundibulum

Fertilization of ovum, fertilized or not process of egg formation continues

Avian magnum

Ovum moves here after fertilization, spends 2-3 hours in magnum, thick albumen (egg white) deposited around yolk

Avian isthmus

Two thin shell membranes deposited around albumen (after magnum), spends 1.5 hours here, ovum takes up water and mineral salts

Avian shell gland/uterus

Spends 18-20 hours here, more albumen added, plumping (water and minerals diffuse in), calcification of shell, pigment added

Avian vagina

Cuticle added, seals pores present in shell

Avian vent/cloaca

Common orifice for copulation, defecation, and egg expulsion

Front (Term)

A: uterine body


B: oviduct


C: cervix


D: uterine horns


E: ovary


F: vagina


G: vulva

Front (Term)

A: testes


B: epididymis


C: scrotum


D: ductus deferens


E: accessory sex glands


F: penis

Testes

Testosterone production (leydig cells), spermatogenesis

Epididymis

Concentration, storage, maturation, and transport of sperm

Scrotum

Support of testes and temperature regulation

Ductus deferens

Sperm transport

Accessory sex glands

Addition of fluid, nutrients, buffers to semen

Penis

Male copulatory organ

What is the passageway of sperm from seminiferous tubules to the epididymis

Ductus deferens

The where, what, when, why, and how of spermatogenesis

Where: seminiferous tubules


What: mitosis and meiosis of male gametes


When: during the breeding season or constitutively


Why: to produce continuous supply of mature male gametes


How: Sertoli cells, leydig cells, blood-testis barrier

hormones of male reproduction:


where are they being produced? what are their target cells? what is the elicited response?

testes; leydig cells; make testosterone in response to LH secretion which causes spermatogenesis

what is the general structure of the spermatozoon?

head (nucleus), midpiece (mitochondria), tail (flagellum)

tissues of the penis:


vascular vs. fibroelastic

vascular: enlarges by retaining blood in the erectile tissue (stallions, humans, dogs)




fibroelastic: increases in length but not diameter, very small amount of blood for erection, straightening of sigmoid flexure by relaxation of retractor penis muscle (bull, ram, boar)

cryptorchidism

when the testes fail to descend


unilateral: one fails