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389 Cards in this Set

  • Front
  • Back
Pulmonary Circuit
carbon dioxide rich blood from heart to lungs and returns oxygen rich blood to heart
Systemic Circuit
oxygen rich blood from heart to the rest of the body and returns carbon dioxide rich blood to the heart
Arteries
transport blood away from the heart
veins
return blood to the heart
capillaries
small vessels that interconnect arteries and veins
what are exchange vessels?
another name for capillaries because their thin walls permit exchange of nutrients, gases, and waste products between blood and tissues
pericardial cavity
heart is located here.
anterior chest wall, posterior to sternum between the 2 pleural cavities in the mediastinum
pericardium
serous membrane lining the pericardial cavity (parietal) and the heart (visceral)
which are the only arteries that carry deoxygenated blood?
the pulmonary arteries
which are the only veins that carry oxygenated blood?
pulmonary veins
types of arteries
elastic, muscular, arterioles
elastic arteries
large vessels that carry large volumes of blood from heart. ex. aorta
muscular arteries
medium sized-distribute blood to skeletal muscles and organs. ex. renal
arterioles
smallest arteries that can change their diameter in response to body conditions
veins
collect blood from all tissues and organs and return it to the heart
arteries
carry blood away from the heart
types of veins
venules, medium-sized, large
venules
smallest veins that collect blood from capillaries
medium-sized veins
correspond to medium-sized arteries
large veins
large vessels that transport large volumes of blood into the heart. ex. superior/inferior vena cava
venous valves
infoldings of the tunica intima that prevent backflow of blood in the veins
3 layers of the heart wall
epicardium, myocardium, endocardium
epicardium
outermost layer of the heart that forms the external surface of the heart (visceral pericardium)
myocardium
middle layer of the heart that consists of interlocking layers of cardiac muscle tissue, associated connective tissue, blood vessels, and nerves
what's the difference between atrial and ventricular myocardium?
atrial is thinner
endocardium
innermost layer of the heart, consists of simple squamous epithelium
cardiocytes
cardiac muscle cells-relatively small cells with centrally placed nucleus, myofibrils, sarcomeres alligned to form striations
intercalated discs
specialized cell junctions unique to cardiac muscle tissue
desmosomes
locks the cell membranes of two cardiac cells together
gap junctions
connect cardiac muscle cells so that an action potential can move from one cell to another as if the membranes were continuous
functional syncytium
"fused mass of cells" describes the contraction of cardiac muscle
fibrous skeleton
internal connective tissue of the heart-collagen and elastin fiber
anatomy of the heart
base is superior portion, apex is inferior portion, superior border=base, right border=right atrium, left border=left ventricle, inferior border=right ventricle
sternocostal surface and diaphragmatic surface
function of the atria
receives venous blood as a passive chamber
auricle
expandable extension of the atrial walls
coronary sulcus
groove that marks the border between the atria and ventricles
function of the ventricles
propel blood around the systemic and pulmonary circuits
anterior interventricular sulcus
depression on anterior surface of the heart-marks the division of the right and left ventricles
posterior interventricular sulcus
depression on the posterior surface of the heart-marks the division of the right and left ventricles
valves of the heart
folds of endocardium that extend into the openings between the atria and ventricles that open and close to prevent backflow of blood
function of right atrium
receives oxygen poor blood from systemic circuit via the superior and inferior vena cava
superior vena cava
opens into the posterior, superior portion of right atrium, delivers venous blood from head, neck, upper limbs and chest
inferior vena cava
opens into posterior and inferior portion of the right atrium, delivers blood from the rest of the trunk, viscera and lower limbs
coronary sinus
collecting vessel in which all coronary veins drain
pectinate muscles
muscular ridges that extend along the inner surface of right atrium
interarial septum
separates right and left atria
fossa ovalis
depression marking remnant of the foramen ovale-fetal opening between right and left atria that closes 48 hrs after birth
function of the right ventricle
receives oxygen poor blood from the right atria via the right atrioventricular valve
chordae tendineae
bundles of collagen fibers to which the cusps of the right atrioventricular valve
papillary muscles
cone shape muscular projections of the inner ventricular surface to which the chordae tendineae attach
function of the papillary muscles
limit movement of valve cusps and prevent backflow of blood
trabeculae carneae
irregular muscular folds of the internal surface of the ventricle
interventricular septum
separates the right and left ventricles
moderator band
ventricular muscle that extends from the interventricular septum to the anterior wall of the right ventricle
conus arteriosus
cone-shaped superior end of the right ventricle
pulmonary semilunar valve
3 thick semilunar cusps that lead to the pulmonary trunk and prevent backflow
pulmonary trunk
start of the pulmonary circuit
right and left pulmonary arteries
branches of the pulmonary trunk that lead to the lungs
right and left pulmonary veins
formed from small veins branching from the pulmonary capillaries and carry blood back to the heart
function of the left atruim
receives oxygen rich blood from the right and left pulmonary veins
left atrioventricular valve
-bicuspid or mitral valve-located between the left atrium and left ventricle to prevent backflow
function of the left ventricle
receive oxygen rich blood from the left atrium, thickest chamber allowing it to force blood around entire systemic circuit
aortic semilunar valve
3 half moon shaped (semilunar) cusps that lead to the ascending aorta and prevent backflow
aortic sinuses
saclike dilations of the base of the ascending aorta that help prevent individual cusps from sticking to the walls of the aorta when the valve opens
aortic branches
ascending aorta-oxygen rich blood from left ventricle ascends from base of heart, aortic arch, descending aorta-descends into thoracic cavity
ligamentum arteriosum
fibrous band that marks the remnant of the ductus arteriosus (fetal circulation)
coronary circulation
supplies blood to heart muscle via the coronary blood vessels
major branches of the right coronary artery
atrial arteries, marginal arteries, posterior interventricular artery, branches to the conducting system
right coronary artery
artery that branches off aorta and follows coronary sulcus
atrial arteries
arteries that supply the myocardium of the right atrium
marginal arteries
branches of the right coronary artery that extend across the ventricular surface
posterior interventricular artery
branch from the right coronary artery in the posterior interventricular sulcus that supplies the septum and portions of ventricles
left coronary artery
artery that branches off the aorta between the left atria and ventricle
branches of the left coronary artery
circumflex artery, anterior interventricular artery
anastomoses
interconnections between arteries
circumflex artery
branch of the left coronary artery that curves to left within the coronary sulcus and reaches the posterior surface of the heart
anterior interventricular artery
branch of the left coronary artery in the anterior interventricular sulcus supplying myocardium of it and anterior ventricular myocardium
cardiac veins
veins that collect blood from myocardial capillaries and deliver it back to the right atrium
direct cardiac veins
anterior cardiac veins that drain the anterior surface of the right ventricle
indirect cardiac veins
deliver blood via the coronary sinus-great, middle, posterior, and small cardiac veins
great cardiac vein
vein that runs in the anterior interventricular sulcus
middle cardiac vein
vein that runs in the posterior interventricular sulcus
posterior cardiac vein
vein that drains the posterior surface of the heart
small cardiac vein
drains the posterior surface of the right atrium and ventricle
systole
contraction/emptying
diastole
relaxation/filling
autorhythmicity
heart contracts on its own without neural or hormonal stimulation
nodal cells
specialized cells that establish the rate of cardiac contraction
conducting fibers within the heart
fibers that distribute the contractile stimulus throughout the myocardium
layers of the walls of a blood vessel
tunica intima-innermost layer of endothelial and CT
tunica media-middle layer of concentric sheets of smooth muscle in loose CT
tunica externa-outermost layer forming a CT sheath
components of the pulmonary circuit
carry deoxygenated blood and include pulmonary trunk, left and right pulmonary arteries, pulmonary veins
components of the systemic circuit
begin at the aortic valve and end at entrance to the right atrium, includes ascending and descending aorta and aortic arch
inferior mesenteric vein
part of hepatic portal system, collects blood from inferior portion of large intestine
left colic vein
part of hepatic portal system, collects blood from descending and sigmoid colon
superior rectal vein
part of hepatic portal system, collects blood from rectum
splenic vein
part of hepatic portal system, formed from the inferior mesenteric vein and veins from spleen, lateral border of stomach, and pancreas
superior mesenteric vein
part of hepatic portal system, collects blood from stomach, small intestine, and first 2/3 of large intestine
umbilical arteries
deliver blood from the fetus to the placenta
umbilical veins
return oxygen rich blood and nutrients from the placenta to the fetus
ductus venosus
fetal circulation-vessel that collects blood from the veins of the liver and from the umbilical vein and delivers it to the inferior vena cava
foramen ovale
fetal interatrial opening which allows blood to flow freely from the right to left atrium, bypassing pulmonary circulation
ductus arteriosus
fetal circulation-small bypass between the pulmonary and aortic trunks, allows for bypass of pulmonary circulation
fossa ovalis
remnant of the foramen ovale
ligamentum arteriosum
remnant of the ductus arteriosus
round ligament
aka ligament teres, remnant of the umbilical vein
circulatory changes at birth
first breath changes internal pressure when lungs and pulmonary vessels expand, this causes fetal shunts to close
2 functional divisions of the respiratory tract
conductive portion-extends from nasal cavity to smallest bronchiole of lung-heats air
respiratory portion-respiratory bronchioles and alveoli-gas exchange
2 anatomical divisions of respiratory tract
upper respiratory system and lower respiratory system
upper respiratory system
filter, warm and humidify air to protect lower resp. system. includes nose, nasal cavity, paranasal sinuses, pharynx
lower respiratory system
larynx, trachea, bronchi, lungs
functions of the respiratory system
gas-exchange between air and blood, breathing, protects resp. surfaces from dehydration, temp changes, variations, pathogens, produces sound, assists in regulating blood volume and composition
respiratory epithelium
pseudostratified ciliated columnar epithelium that lines entire respiratory tract except for inferior part of pharynx and finest portions of alveoli
mucus escalator
cilia in the lower portions of the respiratory tract that beat towards the pharynx and clean the respiratory passageways
vestibule of the nose
portion of nasal cavity supported by nasal cartilage, contains coarse hairs to trap and prevent foreign particles from entering nasal cavity
nasal septum
separates the nasal cavity into right and left portions-bony portion(posterior) ethmoid and vomer bones
soft portion(anterior)hyaline cartilage
turbinate bones
superior, middle and inferior nasal conchae function to create air turbulence and promote filtration, allows time for warming and humidifying of air
meatuses of the nose
superior, middle, and inferior spaces between turbinate bones
hard palate
floor of the nasal cavity formed from the maxillary and palatine bones
soft palate
marks the boundary line between the superior nasopharynx and the rest of the pharynx, uvula at end
internal nares
point where the nasal cavity opens into the nasopharynx
pharynx
shared passageway for respiratory and digestive systems
3 regions of the pharynx
nasopharynx, oropharynx, laryngopharynx
nasopharynx
superior portion of pharynx connected to nasal cavity by internal nares and to oral cavity by soft palate
pharyngeal tonsils
lymphoid function, on posterior wall of nasopharynx
auditory tube
located on lateral wall of the nasopharynx and leads to inner ear
oropharynx
middle of the pharynx, extends from soft palate and base of tongue-lining is stratified squamous epithelium
uvula
posterior edge of soft palate
pharyngeal arches
posterior edge of the soft palate-palatoglossal arch and palatopharyngeal arch, with openings called fauces
laryngopharynx
inferior portion of pharynx, between hyoid bone and entrance to esophagus-lined by stratified squamous epithelium
larynx
voice box-surrounds and protects the glottis
glottis
narrow opening air passes through as it leaves the pharynx
laryngeal cartilages
thyroid-largest, forms anterior and lateral walls of larynx (adams apple)
cricoid-inferior to thyroid cartilage
both protect glottis and entrance to trachea
epiglottis
superior to glottis, supported by epiglottal cartilage-folds over glottis during swallowing
paired laryngeal cartilages
2 arytenoid, 2 corniculate, 2 cuneiform
laryngeal ligaments
intrinsic-bind all 9 cartilages
extrinsic-attach larynx to hyoid and trachea
vocal-between thyroid and arytenoid cartilages
vestibular-between thyroid and arytenoid cartilages
vestibular folds
false vocal cords, mucosal folds in the laryngeal wall that have a protective function
vocal folds
true vocal cords-folds in laryngeal wall that produce sound
laryngeal musculature
intrinsic-regulate tension in vocal folds, open/close glottis
extrinsic-position/stabilize larynx
trachea
windpipe-begins anterior to C6 continues to T5 where it branches into right/left primary bronchi
connective tissue of the trachea
lamina propria that overlays the epithelium
anular ligaments
bind the 15-20 c-shaped tracheal cartilages to one another
primary bronchi
extrapulmonary structures (located outside lungs), right and left distal branches of trachea
carina
ridge on the base of the trachea that marks its division into the primary bronchi
hilus
region of the lung where right and left primary bronchi enter (as well as blood vessels)
regions of the lungs
apex-conical tip that points superiorly
base-concave inferior portion that rests on the superior surface of the diaphragm
lobes of the lung
superior, middle, inferior in right lung
superior and inferior in the left lung
horizontal fissure
separates superior and middle lobes of the right lung
oblique fissure
one separates superior and inferior lobes of the right lung, another separates same in the left lung
cardiac notch
concavity formed from position of heart in the mediastinum
lung surfaces
costal surface-anterior surface,faces ribs
mediastinal surface-medial surface, hilus located on it
diaphragmatic surface-inferior surface that faces diaphragm
bronchopulmonary segments
segments of lungs that are smaller than lobes and are associated with a single tertiary bronchus
bronchial tree
formed from the primary bronchi and their branches
primary bronchi
extrapulmonary structures that divide into smaller branches, called intrapulmonary bronchi, as they enter the lung
right primary bronchus
divides into 3 secondary bronchi:superior, middle, inferior lobar bronchi
left primary bronchus
divides into 2 secondary bronchi:superior and inferior lobar bronchi
tertiary bronchi
aka segmental
serve each bronchopulmonary segment (walls of secondary and tertiary bronchi contain cartilage plates)
terminal bronchioles
divisions of tertiary bronchi, walls lack cartilage support, made of smooth muscle
sympathetic stimulation of the bronchioles
leads to enlargement of the airway, or bronchodilation
parasympathetic stimulation of the bronchioles
leads to bronchoconstriction
respiratory bronchioles
branches of the terminal bronchioles that deliver air to each individual lung lobule
alveolar ducts
passageways that connect respiratory bronchioles to alveoli
alveolar sacs
terminal ends of alveolar ducts that connect several alveoli
alveoli
pockets at the end of the bronchial tree where gas exchange with the blood occurs-lined with simple squamous epithelium called type 1 cells, or respiratory epitheliocytes
septal cells
type II cells or surfactant cells-scattered among the epithelium and secrete surfactant, an oily secretion that reduces surface tension in the fluid coating alveolar surface
alveolar macrophages
phagocytic cells within the epithelium
respiratory membrane
area of gas exchange, formed fusion of the basement membrane of alveolar epithelium and adjacent capillaries
where do the pulmonary arteries enter the lung?
at the hilus where they branch with the bronchi as they approach each lobule
blood supply to each lobule
each lobule receives an arteriole, venule, and a network of capillaries that surrounds each alveolus
alveolar capillaries
provide a mechanism for gas exchange and are primary source of ACE, which converts circulating angiotensin I to angiotensin II
angiotensin II
a hormone involved with regulation of blood volume and pressure
pulmonary ventilation
breathing-movement of air into and out of bronchial tree
alveolar ventilation
prevents build up of CO2 and ensures continuous supply of O2
respiratory muscles
diaphragm, external intercostals, internal intercostals, accessory muscles
diaphragm
contraction increases the volume of the thoracic cavity by flattening its floor, this draws air into the lungs (inhalation)
external intercostals
muscles that assist by elevating ribs during inhalation
internal intercostals
muscles that depress the ribs and reduce the width of the thoracic cavity (exhalation)
accessory respiratory muscles
active when the depth and frequency of respiration must be increased
eupnea
quiet, normal breathing that involves muscular contractions, but expiration is passive
diaphragmatic breathing
deep breathing, contraction of the diaphragm provides necessary change in thoracic volume drawing in air, exhalation occurs when diaphragm relaxes
costal breathing
shallow breathing-thoracic volume changes because rib cage changes shape, contraction of external intercostal muscles elevate ribs and enlarges thoracic cavity-inhalation, muscles relax-exhalation
hypernea
forced breathing that involves active inhalation and exhalation, accessory muscles assist (heavy exercise)
breathing control in the brain
respiratory control centers are located in the pons and medulla oblongata
functions of the digestive system
ingestion, mechanical processing , digestion, secretion, absorption, compaction, excretion
4 major layers of the digestive tract
mucosa, submucosa, muscularis externa, serosa
mucosa
inner lining of digestive tract made up of epithelium containing plicae, areolar CT called lamina propria that is covered by the muscularis mucosae-layer of smooth muscle and elastic fibers
plicae
tranverse or longitudinal folds that increase surface area for absorption in digestive tract
muscularis mucosae
outermost layer of the mucosa, two concentric layers-circular inner layer that encircles lumen and longitudinal outer layer with parallel fibers
submucosa
layer of areolar tissue that surrounds the muscularis mucosae-contains blood vessels, lymphatics, exocrine glands that secrete buffers and enzymes
submucosal plexus
network of fibers and scattered neuron cell bodies that innervate the mucosa
muscularis externa
layer of smooth muscle that surrounds the submucosa and contains circular (inner) and longitudinal (outer) muscle layers
myenteric plexus
network of autonomic ganglia and fibers between the circular and longitudinal layers
parasympathetic stimulation of myenteric plexus
increases muscular tone and stimulates contraction
sympathetic stimulation of myenteric plexus
promotes inhibition of muscular activity and relaxation
sphincters
thickened areas of circular muscle that prevent material from moving along the tract at an inappropriate time or in the wrong direction
serosa
serous membrane that covers the muscularis externa, located in most regions of digestive tract
adventitia
dense network of collagen fibers that covers the muscularis externa of the oral cavity, pharynx, esophagus, and rectum, instead of a serosa layer
accessory structures of the digestive system
teeth, tongue, liver, gallbladder, pancreas, salivary gland
organs and structures of the digestive tract
pharynx, esophagus, stomach, small intestine, large intestine, oral cavity
contractile proteins of smooth muscle
do not form sarcomeres but are capable of strong contraction
plasticity
ability of smooth muscle cells to stretch and adapt to a new length, then contract again
2 types of movement in digestive tract
peristalsis and segmentation
peristalsis
contractions of the muscularis externa that propel material through the digestive tract
bolus
small oval mass of food
peristaltic wave
event where the circular muscles contract behind digestive contents, then longitudinal muscles contract shortening adjacent segements, finally a 2nd wave of contraction in circular muscles forces the material in the desired direction
segmentation
movements in areas of the small intestine that churn digestive materials, mix the contents with intestinal secretions, but produce no net movement
mesenteries
fused, double sheets of peritoneal membrane that stabilize attached organs
greater omentum
"fatty apron" double layer of mesentery that hangs anteriorly from the stomach
lesser omentum
mesentery that runs between the stomach and liver
mesentery proper
suspends and wraps the small intestine, provides stability but permits a degree of independent movement
mesocolon
suspends and wraps the colon and includes the transverse and sigmoid mesocolon
functions of oral cavity
analysis of material before swallowing, mechanical processing with teeth etc, lubrication by mixing mucous and salivary secretions, limited digestion of carbs by salivary enzymes
buccal cavity
lined with oral mucosa of stratified squamous epithelium that does not keratinize and protects the mouth from abrasion
what supports the oral cavity mucosa
buccal fat pads and buccinator muscle
vestibule of oral cavity
space between cheeks, lips and teeth
what forms the roof of the oral cavity?
hard and soft palates
uvula
structure that dangles from the center of the soft palate
what organ forms the floor of the oral cavity?
tongue
parts of the tongue
body-anterior oral portion
root-point of attachment
dorsum-contains numerous fine projections called papillae
frenulum-thin fold of mucus membrane that connects the tongue to the mucosa of the oral floor
muscles of the tongue
intrinsic muscles within tongue and extrinsic muscles outside of tongue
3 pairs of salivary glands
parotid, sublingual, submandibular
parotid glands
largest salivary glands, on lateral side of face anterior to ear, ducts drain into vestibule near 2nd upper molar
sublingual glands
salivary glands that are covered by the mucous membrane of the floor of the mouth, ducts drain near lingual frenulum
submandibular glands
located near the medial surface of mandible, ducts drain on either side of the lingual frenulum
saliva
70% submandibular, 25% parotid, 5% sublingual, contains salivary amylase to begin carb digestion, mucins that are glycoproteins for lubrication
structure of teeth
inner matrix dentin surrounded by crystals called enamel, pulp cavity, root canal, apical foramen, periodontal ligament, crown, neck, gingival sulcus
dentin
mineral matrix in tooth, covered by densely packed calcium crystals
pulp cavity
spongy, highly vascular hollow inside of a tooth that contains blood vessels and nerves
root canal
narrow tunnel located at the base, or root of the tooth
apical foramen
opening into root through which blood vessels and nerves enter
periodontal ligament
collagen fibers anchor the tooth to its bony socket
crown
exposed surface of the tooth
neck of tooth
marks the boundary between the root and the crown
gingival sulcus
where gum and tooth meet
types of teeth
8 incisor, 4 cuspids, 8 bicuspids, 12 molars
dental succession
deciduous-(primary, baby, milk) 20 teeth replaced by
permanent-(secondary) 32 teeth
3 phases of swallowing
buccal, pharyngeal, esophageal
buccal phase of swallowing
compression of bolus against hard palate, followed by retraction of tongue forcing bolus into pharynx and elevating soft palate. voluntary until enters oropharynx
pharyngeal phase of swallowing
when bolus touches posterior pharyngeal wall the larynx elevates and the epiglottis folds pushing the bolus towards the esophagus
esophageal phase of swallowing
upper esophageal sphincter opens, peristalsis begins and lower esophageal sphincter opens
esophagus
transports food and liquids to the stomach, folds run length to allow expansion, no serosa, adventitia anchors esophagus in position against dorsal body wall
stomach
j-shaped organ that occupies the left hypochondriac, epigastric, and portions of the umbilical region of the abdominal cavity
chyme
semi-fluid mixture of ingested food and digestive secretions that is found in stomach
anatomy of stomach
lesser curvature-medial surface,greater curvature-lateral surface,rugae, regions:cardia,fundus,body,pylorus
cardia region of stomach
located under the heart
cardiac orifice
opening connected with the esophageal lumen
fundus of stomach
bulge above the esophageal opening that contacts the diaphragm
body of stomach
largest region, functions as a mixing tank for ingested food and gastric secretions
pylorus
inferior end that terminates at the muscular pyloric sphincter, which regulates the release of chyme into the first portion of the small intestine
rugae of the stomach
longitudinal folds of the stomach mucosa that permit expansion of the gastric lumen
mesenteries associated with stomach
greater and lesser omentum
musculature of the stomach
muscularis mucosae and muscularis externa contain an extra layer-outer longitudinal, middle circular, and inner oblique for added strength
lining of stomach
simple columnar epithelium forms a secretory sheet
gastric pits
depressions that open into the gastric surface, mucous cells at the base of each pit divide to replace superficial cells shed into chyme
gastric glands
simple branched tubular glands found in the underlying lamina propria
3 types of cells found in gastric glands
parietal, chief, and enteroendocrine
parietal cells
secrete HCl to kill micoorganisms, break down cell walls of food, and activate chief cells, and secrete intrinsic factor that facilitates absorption of vitamin b12
chief cells
secrete pepsinogen the inactive form that is converted by acids to pepsin, and secretes rennin and gastric lipase that are important for newborn milk digestion
enterendocrine cells
G cells=most abundant, secrete gastrin-hormone that stimulates the activity of parietal and chief cells and promotes smooth muscle activity in stomach, released when food enters stomach
regulation of stomach
CNS,ANS,vagus nerve, celiac plexus, hormones released by small intestine via stimulation by liver and pancreas, parasympathetic stimulates gastric juice production, sympathetic inhibits gastric secretions
hormones that regulate the stomach
cholecystokinin and secretin
small intestine
plays the primary (90%) role in digestion and absorption of nutrients, in all abdominal regions but left hypochondriac and epigastric
plicae circularis
transverse folds of the intestinal lining that function to increase surface area
regions of the small intestine
duodenum, jejunum, ileum
duodenum
retroperitoneal, c-shaped, shortest and widest portion connected to the pylorus of the stomach that functions as a mixing bowl that receives chyme from the stomach and digestive enzymes from the pancreas and liver
pyloric sphincter
guards the connection of the pylorus and duodenum which functions to prevent backflow
jejunum
second portion of the small intestine where the bulk of chemical digestion and nutrient absorption occurs
duodenojejunal flexure
curve that marks the point where the duodenum becomes the jejunum
ileum
3rd and final portion of the small intestine that functions primarily for absorption
ileocecal valve
junction between large and small intestines, controls the flow of material
duodenum
no supporting mesentery because it is retroperitoneal it is fixed in position between L1 and L4
what supports the jejunum and ileum?
supported by the mesentery proper
intestinal villi
fingerlike projections formed by the mucosa, covered by simple columnar epithelium
microvilli
sub-microscopic size projections on single cells of villi. brush boarder appearance
intestinal crypts
pockets at the base of each villus that extend deep into the underlying lamina propria
duodenal submucosal glands
aka brunner's glands-produce mucus that protects the epithelium from the acid chyme arriving from the stomach and contains buffers that help elevate the pH of chyme
duodenal papilla
point where the common bile duct of the liver and gallbladder and the pancreatic duct from the pancreas come together
duodenal ampulla
entry point for the duodenal papilla duct
function of the duodenum
mixing and churning
function of the jejunum and ileum
absorption
aggregate lymphoid nodules
peyer's patches-lymphoid centers near the entrance to the large intestine, contains numbers of potentially harmful bacteria
regulation of the small intestine
nervous system-local reflexes, parasympathetic stimulates secretions, sympathetic inhibits secretions, hormones-cholecystokinin and secretin regulate and coordinate secretory activities of stomach, duodenum, liver, pancreas
large intestine
colon-inferior to stomach and liver, reabsorbs water and electrolytes, compacts contents to feces, absorbs vitamins produced by bacteria, stores fecal material
cecum
expanded pouch at proximal end of colon
ileal papilla
opening of ileum into the cecum
ileocecal valve
covers ileal papilla and regulates the passage of material
vermiform appendix
lymphoid tissue attached to surface of cecum and suspended by a band of mesentery called mesoappendix
haustra
pouches along the walls of the colon that permit considerable distension and elongation created by muscle tone
taeniae coli
3 separate longitudinal ribbons of smooth muscle
epiploic appendages
fatty appendages-fat sacs of the serosa of the colon
ascending colon
retroperitoneal structure with no mesentery associated
right colic flexure
hepatic flexure-point where the ascending colon meets the liver and turns right
transverse colon
supported by the transverse mesocolon and separated from the anterior abdominal wall by the greater omentum
gastrocolic ligament
attaches the transverse colon to the greater curvature of the stomach
left colic flexure
aka splenic flexure-point where the transverse colon makes a right angle and bends towards the spleen
descending colon
begins at the left colic flexure and runs down the left side of the abdomen until it begins to curve into the sigmoid flexure
sigmoid colon
s-shaped distal region of the colon that lies posterior to the bladder and empties into the rectum, suspended by the sigmoid mesocolon
rectum
expandable organ for temporary storage of fecal matter
anal canal
contains small logitudinal folds called anal columns
anus
terminal end of the anal canal
internal sphincter
involuntary, formed from the circular muscle layer of the muscularis externa in this region
external sphincter
voluntary skeletal muscle sphincter that encircles the distal portion of the anal canal
histology of the large intestine
large diameter, thinner walls that small intestine
lacks villi
more abundant goblet cells
regulation of large intestine
haustral churning-segmentation movements of the LI
mass movements-periodic peristalsis stimulated by distension of the stomach and duodenum
accessory digestive organs
produce and store enzymes and buffers that are essential to normal digestive function
liver
largest visceral organ that provides metabolic regulation, hematological regulation, synthesis and secretion of bile
metabolic regulation by the liver
all blood leaving the absorptive surfaces of digestive tract enter the hepatic portal system and nutrients and toxins can be extracted from blood before it enters systemic circulation
synthesis and secretion of bile
bile is stored in the gallbladder and excreted into the lumen of the duodenum where bile salts associate with lipids in chyme so enzymes can break them down into fatty acids
lobes of the liver
right, left, quadrate, caudate
falciform ligament
marks the division between the right and left lobes
round ligament
aka ligamentum teres-in the liver-fibrous band that marks the degenerated umbilical vein
coronary ligament
between liver and diaphragm
hilus of the liver
porta hepatis-underside entry point for blood vessels and ducts
basic functional units of the liver
liver lobules
hepatocytes
liver cells-arranged around a central vein which creates a series of irregular plates inside each lobule
kupffer cells
phagocytic cells found in the lobule lining
composition of bile
water, minor amts of irons, bilirubin and bile salts
canaliculi
passageways between liver cells that extend outward through each liver lobule and eventually connect with bile ducts by ductules
right and left hepatic ducts
collect bile from ducts of the liver lobes
common hepatic duct
formed from the unity of the right and left hepatic ducts, from it bile enters the gallbladder via the cystic duct or enters the duodenum
common bile duct
common hepatic duct and cystic duct-empties into duodenum at papilla
gallbladder
hollow, pear shaped muscular organ that stores and concentrates bile before its secretion into duodenum
pancreas
retroperitoneal organ that extends laterally from the duodenum towards the spleen
structure of the pancreas
head-near duodenum
body
tail-near spleen
function of the pancreas
exocrine organ producing digestive enzymes and buffers, also has endocrine functions
pancreatic duct
delivers pancreatic secretions to the duodenal ampulla
histology of the pancreas
lumpy nodular texture, lobules are partitioned by CT, acini produce pancreatic juice (mix of water, ion and pancreatic digestive enzymes)
pancreatic enzymes
lipases, carbohydrases, nucleases, proteolytic enzymes including proteinases and peptidases
regulation of pancreas
secretion of juices in response to hormonal instruction from the duodenum. secretin and cholecystokinin
nephron
basic structural and functional unit of the kidney
proximal convoluted tubule
reabsorbs water, ions, all organic nutrients
part of nephron
renal corpuscle
produces filtrate, filters out stuff the body still wants so this filtrate still contains things the body wants. filtrate=tubular fluid
part of nephron
distal convoluted tubule
part of nephron-secretes ions, acids, drugs, toxins, variable reabsorption under hormonal control
connecting tubules and collecting duct
part of nephron-variable reabsorption of H2O and reabsorption/secretion of sodium, potassium, hydrogen, bicarbonate ion
papillary duct
part of nephron-delivers urine to minor calyx
loop of henle
part of nephron-further reabsorption of water in the descending limb, and Na+ and Cl- in ascending limb
micturition
urination
urinary system
kidneys and urinary tract (ureters, urinary bladder, urethra)
right kidney surface features
anterior surface is covered by the liver, hepatic flexure of the colon and the duodenum. superior surface is capped by adrenal gland
left kidney surface features
anterior surface is covered by the spleen, stomach, pancreas, jejunum, and splenic flexure of the colon. superior surface is capped by adrenal gland
3 concentric layers of CT that protect the kidney
renal capsule-fibrous tunic-layer of collagen fibers
adipose capsule-perirenal fat-layer of adipose that surrounds the renal capsule
renal fascia-superficial layer of collagen that anchors kidney to surroundings
hilus of kidney
opening on medial side that marks the entry for renal artery and exit for renal vein and ureter
renal sinus
region inside the kidney where renal blood vessels and nerves branch
cortex of kidney
reddish-brown, granular outer layer
medulla of kidney
internal to the cortex and consists of 6-18 distinct conical structures, called renal pyramids
renal papilla
tip of each renal pyramid
renal columns
bands of cortical tissue that separate each renal pyramid
renal lobe
consists of renal pyramid, overlying area of renal cortex, adjacent tissues of the renal columns-urine produced here
minor calyx
cup shaped region inferior to each renal papilla-collects discharged urine
major calyx
formed from the merging of 4-5 minor calyces
renal pelvis
large, funnel-shaped chamber formed from the merging of the major calyces
blood supply of kidney
receives 20-25% of total cardiac output, renal artery and renal vein
glomerulus
part of nephron-capillary network where filtration occurs
afferent arteriole of kidney
brings blood to the glomerulus
efferent arteriole of kidney
carries blood away from glomerulus
glomerular filtrate
protein-free solution produced from filtration across the glomerulus
cortical nephrons
located almost entirely within cortex-85%
juxtamedullary nephrons
located closer to the medulla-15%
visceral (glomerular) epithelium
large cells called podocytes that wrap around glomerular capillaries
capsular space
separates the parietal and visceral epithelium
vascular pole
marks the connection of the parietal and visceral epithelium and the connection of the glomerular capillaries to the bloodstream
filtration
occurs as blood pressure forces fluid and dissolved solutes out of the glomerulus into the capsular space
capillary endothelium
contains openings that are small enough to prevent passage of blood cells but are to large to restrict diffusion of solutes
basement membrane of the nephrons
surrounds the capillary endothelium and has several times the density and thickness that is typical. called the "lamina densa" restricts passage of smaller plasma proteins, nutrients, ions
filtration slits
narrow gaps that separate pedicles (processes of glomerular epithelium that wrap around basement membrane) and allow for only water with dissolved ions, small organic molecules, and few plasma proteins to pass
lining of the PCT
(proximal convoluted tubule)-simple cuboidal epithelium with microvilli
descending limb of the loop of henle
travels in the medulla toward the renal pelvis
ascending limb of the loop of henle
returns toward the cortex
vasa recta
slender capillaries that absorb water from that flows out of the nephron from the loop of henle, returns it to general circulation
DCT versus PCT
DCT has smaller diameter, lacks microvilli, epithelial cells have distinct boundaries, function is secretion as opposed to absorption
juxtaglomerular apparatus
endocrine structure formed from structures of the DCT that secretes 2 hormones, renin and erythropoietin-elevate blood volume, hemoglobin levels, blood pressure, restore normal rate of filtration production
collecting system of the kidney
connecting tubule carries filtrate from DCT to collecting duct which leaves the cortex and descends into the medulla toward a papillary duct that drains into the renal pelves
transitional epithelium
tolerates cycles of distension and contraction, found in minor and major calyces, renal pelvis, ureters,urinary bladder, proximal portion of urethra
ureters
paired muscular tubes that begin as continuation of renal pelvis, exit kidney via hilus, extend approx. 12 inches to urinary bladder
walls of the ureters
inner mucosa-lined by transitional epithelium
middle muscular layer of longitudinal (inner) and circular (outer) smooth muscle
outer CT layer is continuous with fibrous renal capsule
male urinary bladder
base lies between rectum and symphysis pubis
female urinary bladder
base sits inferior to the uterus and anterior to vagina
median umbilical ligament
aka urachus-peritoneal fold that extends from the anterior and superior border to the umbilicus
lateral umbilical ligaments
peritoneal folds that pass along the sides of the bladder to reach the umbilicus
trigone
triangular area bounded by ureteral openings and entrance to the urethra-lacks rugae, smooth and thick, funnel that channels urine into the urethra when bladder contracts
neck of bladder
region surrounding the urethral opening
internal urethral sphincter
smooth muscle that provides involuntary control over the discharge of urine from the bladder-autonomic control
detrusor muscle
formed from the longitudinal and smooth muscle layers of the urinary bladder-contraction compresses the bladder and expels its contents
walls of urinary bladder
mucosa,submucosa,muscularis, serosa
female urethra
1-1.5 inches, extends from bladder to vestibule
external urethral meatus
external opening situated near the anterior wall of the vagina
male urethra
7-8 inches, 3 portions-prostatic urethra passes through prostate-membranous urethra short and penetrates muscular floor of pelvic cavity-penile urethra distal segment extends from urogenital diaphragm to tip of penis
external urethral sphincter
circular band of skeletal muscle under voluntary control
histology of urethra
females-transitional epithelium near bladder, rest is stratified squamous
males-neck of bladder to external urethral meatus changes from transitional to pseudostratified columnar or columnar, then stratified squamous
calcitrol
synthesized by the urinary system, hormone derivative of vitamin D3 that stimulates calcium ion absorption in the intestine