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389 Cards in this Set
- Front
- Back
Pulmonary Circuit
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carbon dioxide rich blood from heart to lungs and returns oxygen rich blood to heart
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Systemic Circuit
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oxygen rich blood from heart to the rest of the body and returns carbon dioxide rich blood to the heart
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Arteries
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transport blood away from the heart
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veins
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return blood to the heart
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capillaries
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small vessels that interconnect arteries and veins
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what are exchange vessels?
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another name for capillaries because their thin walls permit exchange of nutrients, gases, and waste products between blood and tissues
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pericardial cavity
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heart is located here.
anterior chest wall, posterior to sternum between the 2 pleural cavities in the mediastinum |
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pericardium
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serous membrane lining the pericardial cavity (parietal) and the heart (visceral)
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which are the only arteries that carry deoxygenated blood?
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the pulmonary arteries
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which are the only veins that carry oxygenated blood?
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pulmonary veins
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types of arteries
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elastic, muscular, arterioles
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elastic arteries
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large vessels that carry large volumes of blood from heart. ex. aorta
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muscular arteries
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medium sized-distribute blood to skeletal muscles and organs. ex. renal
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arterioles
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smallest arteries that can change their diameter in response to body conditions
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veins
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collect blood from all tissues and organs and return it to the heart
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arteries
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carry blood away from the heart
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types of veins
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venules, medium-sized, large
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venules
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smallest veins that collect blood from capillaries
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medium-sized veins
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correspond to medium-sized arteries
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large veins
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large vessels that transport large volumes of blood into the heart. ex. superior/inferior vena cava
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venous valves
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infoldings of the tunica intima that prevent backflow of blood in the veins
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3 layers of the heart wall
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epicardium, myocardium, endocardium
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epicardium
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outermost layer of the heart that forms the external surface of the heart (visceral pericardium)
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myocardium
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middle layer of the heart that consists of interlocking layers of cardiac muscle tissue, associated connective tissue, blood vessels, and nerves
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what's the difference between atrial and ventricular myocardium?
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atrial is thinner
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endocardium
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innermost layer of the heart, consists of simple squamous epithelium
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cardiocytes
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cardiac muscle cells-relatively small cells with centrally placed nucleus, myofibrils, sarcomeres alligned to form striations
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intercalated discs
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specialized cell junctions unique to cardiac muscle tissue
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desmosomes
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locks the cell membranes of two cardiac cells together
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gap junctions
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connect cardiac muscle cells so that an action potential can move from one cell to another as if the membranes were continuous
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functional syncytium
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"fused mass of cells" describes the contraction of cardiac muscle
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fibrous skeleton
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internal connective tissue of the heart-collagen and elastin fiber
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anatomy of the heart
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base is superior portion, apex is inferior portion, superior border=base, right border=right atrium, left border=left ventricle, inferior border=right ventricle
sternocostal surface and diaphragmatic surface |
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function of the atria
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receives venous blood as a passive chamber
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auricle
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expandable extension of the atrial walls
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coronary sulcus
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groove that marks the border between the atria and ventricles
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function of the ventricles
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propel blood around the systemic and pulmonary circuits
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anterior interventricular sulcus
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depression on anterior surface of the heart-marks the division of the right and left ventricles
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posterior interventricular sulcus
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depression on the posterior surface of the heart-marks the division of the right and left ventricles
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valves of the heart
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folds of endocardium that extend into the openings between the atria and ventricles that open and close to prevent backflow of blood
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function of right atrium
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receives oxygen poor blood from systemic circuit via the superior and inferior vena cava
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superior vena cava
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opens into the posterior, superior portion of right atrium, delivers venous blood from head, neck, upper limbs and chest
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inferior vena cava
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opens into posterior and inferior portion of the right atrium, delivers blood from the rest of the trunk, viscera and lower limbs
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coronary sinus
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collecting vessel in which all coronary veins drain
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pectinate muscles
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muscular ridges that extend along the inner surface of right atrium
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interarial septum
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separates right and left atria
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fossa ovalis
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depression marking remnant of the foramen ovale-fetal opening between right and left atria that closes 48 hrs after birth
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function of the right ventricle
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receives oxygen poor blood from the right atria via the right atrioventricular valve
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chordae tendineae
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bundles of collagen fibers to which the cusps of the right atrioventricular valve
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papillary muscles
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cone shape muscular projections of the inner ventricular surface to which the chordae tendineae attach
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function of the papillary muscles
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limit movement of valve cusps and prevent backflow of blood
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trabeculae carneae
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irregular muscular folds of the internal surface of the ventricle
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interventricular septum
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separates the right and left ventricles
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moderator band
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ventricular muscle that extends from the interventricular septum to the anterior wall of the right ventricle
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conus arteriosus
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cone-shaped superior end of the right ventricle
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pulmonary semilunar valve
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3 thick semilunar cusps that lead to the pulmonary trunk and prevent backflow
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pulmonary trunk
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start of the pulmonary circuit
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right and left pulmonary arteries
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branches of the pulmonary trunk that lead to the lungs
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right and left pulmonary veins
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formed from small veins branching from the pulmonary capillaries and carry blood back to the heart
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function of the left atruim
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receives oxygen rich blood from the right and left pulmonary veins
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left atrioventricular valve
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-bicuspid or mitral valve-located between the left atrium and left ventricle to prevent backflow
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function of the left ventricle
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receive oxygen rich blood from the left atrium, thickest chamber allowing it to force blood around entire systemic circuit
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aortic semilunar valve
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3 half moon shaped (semilunar) cusps that lead to the ascending aorta and prevent backflow
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aortic sinuses
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saclike dilations of the base of the ascending aorta that help prevent individual cusps from sticking to the walls of the aorta when the valve opens
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aortic branches
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ascending aorta-oxygen rich blood from left ventricle ascends from base of heart, aortic arch, descending aorta-descends into thoracic cavity
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ligamentum arteriosum
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fibrous band that marks the remnant of the ductus arteriosus (fetal circulation)
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coronary circulation
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supplies blood to heart muscle via the coronary blood vessels
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major branches of the right coronary artery
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atrial arteries, marginal arteries, posterior interventricular artery, branches to the conducting system
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right coronary artery
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artery that branches off aorta and follows coronary sulcus
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atrial arteries
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arteries that supply the myocardium of the right atrium
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marginal arteries
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branches of the right coronary artery that extend across the ventricular surface
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posterior interventricular artery
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branch from the right coronary artery in the posterior interventricular sulcus that supplies the septum and portions of ventricles
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left coronary artery
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artery that branches off the aorta between the left atria and ventricle
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branches of the left coronary artery
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circumflex artery, anterior interventricular artery
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anastomoses
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interconnections between arteries
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circumflex artery
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branch of the left coronary artery that curves to left within the coronary sulcus and reaches the posterior surface of the heart
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anterior interventricular artery
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branch of the left coronary artery in the anterior interventricular sulcus supplying myocardium of it and anterior ventricular myocardium
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cardiac veins
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veins that collect blood from myocardial capillaries and deliver it back to the right atrium
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direct cardiac veins
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anterior cardiac veins that drain the anterior surface of the right ventricle
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indirect cardiac veins
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deliver blood via the coronary sinus-great, middle, posterior, and small cardiac veins
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great cardiac vein
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vein that runs in the anterior interventricular sulcus
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middle cardiac vein
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vein that runs in the posterior interventricular sulcus
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posterior cardiac vein
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vein that drains the posterior surface of the heart
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small cardiac vein
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drains the posterior surface of the right atrium and ventricle
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systole
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contraction/emptying
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diastole
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relaxation/filling
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autorhythmicity
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heart contracts on its own without neural or hormonal stimulation
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nodal cells
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specialized cells that establish the rate of cardiac contraction
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conducting fibers within the heart
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fibers that distribute the contractile stimulus throughout the myocardium
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layers of the walls of a blood vessel
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tunica intima-innermost layer of endothelial and CT
tunica media-middle layer of concentric sheets of smooth muscle in loose CT tunica externa-outermost layer forming a CT sheath |
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components of the pulmonary circuit
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carry deoxygenated blood and include pulmonary trunk, left and right pulmonary arteries, pulmonary veins
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components of the systemic circuit
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begin at the aortic valve and end at entrance to the right atrium, includes ascending and descending aorta and aortic arch
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inferior mesenteric vein
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part of hepatic portal system, collects blood from inferior portion of large intestine
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left colic vein
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part of hepatic portal system, collects blood from descending and sigmoid colon
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superior rectal vein
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part of hepatic portal system, collects blood from rectum
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splenic vein
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part of hepatic portal system, formed from the inferior mesenteric vein and veins from spleen, lateral border of stomach, and pancreas
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superior mesenteric vein
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part of hepatic portal system, collects blood from stomach, small intestine, and first 2/3 of large intestine
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umbilical arteries
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deliver blood from the fetus to the placenta
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umbilical veins
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return oxygen rich blood and nutrients from the placenta to the fetus
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ductus venosus
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fetal circulation-vessel that collects blood from the veins of the liver and from the umbilical vein and delivers it to the inferior vena cava
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foramen ovale
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fetal interatrial opening which allows blood to flow freely from the right to left atrium, bypassing pulmonary circulation
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ductus arteriosus
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fetal circulation-small bypass between the pulmonary and aortic trunks, allows for bypass of pulmonary circulation
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fossa ovalis
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remnant of the foramen ovale
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ligamentum arteriosum
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remnant of the ductus arteriosus
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round ligament
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aka ligament teres, remnant of the umbilical vein
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circulatory changes at birth
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first breath changes internal pressure when lungs and pulmonary vessels expand, this causes fetal shunts to close
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2 functional divisions of the respiratory tract
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conductive portion-extends from nasal cavity to smallest bronchiole of lung-heats air
respiratory portion-respiratory bronchioles and alveoli-gas exchange |
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2 anatomical divisions of respiratory tract
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upper respiratory system and lower respiratory system
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upper respiratory system
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filter, warm and humidify air to protect lower resp. system. includes nose, nasal cavity, paranasal sinuses, pharynx
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lower respiratory system
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larynx, trachea, bronchi, lungs
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functions of the respiratory system
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gas-exchange between air and blood, breathing, protects resp. surfaces from dehydration, temp changes, variations, pathogens, produces sound, assists in regulating blood volume and composition
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respiratory epithelium
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pseudostratified ciliated columnar epithelium that lines entire respiratory tract except for inferior part of pharynx and finest portions of alveoli
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mucus escalator
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cilia in the lower portions of the respiratory tract that beat towards the pharynx and clean the respiratory passageways
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vestibule of the nose
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portion of nasal cavity supported by nasal cartilage, contains coarse hairs to trap and prevent foreign particles from entering nasal cavity
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nasal septum
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separates the nasal cavity into right and left portions-bony portion(posterior) ethmoid and vomer bones
soft portion(anterior)hyaline cartilage |
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turbinate bones
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superior, middle and inferior nasal conchae function to create air turbulence and promote filtration, allows time for warming and humidifying of air
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meatuses of the nose
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superior, middle, and inferior spaces between turbinate bones
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hard palate
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floor of the nasal cavity formed from the maxillary and palatine bones
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soft palate
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marks the boundary line between the superior nasopharynx and the rest of the pharynx, uvula at end
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internal nares
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point where the nasal cavity opens into the nasopharynx
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pharynx
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shared passageway for respiratory and digestive systems
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3 regions of the pharynx
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nasopharynx, oropharynx, laryngopharynx
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nasopharynx
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superior portion of pharynx connected to nasal cavity by internal nares and to oral cavity by soft palate
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pharyngeal tonsils
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lymphoid function, on posterior wall of nasopharynx
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auditory tube
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located on lateral wall of the nasopharynx and leads to inner ear
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oropharynx
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middle of the pharynx, extends from soft palate and base of tongue-lining is stratified squamous epithelium
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uvula
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posterior edge of soft palate
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pharyngeal arches
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posterior edge of the soft palate-palatoglossal arch and palatopharyngeal arch, with openings called fauces
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laryngopharynx
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inferior portion of pharynx, between hyoid bone and entrance to esophagus-lined by stratified squamous epithelium
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larynx
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voice box-surrounds and protects the glottis
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glottis
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narrow opening air passes through as it leaves the pharynx
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laryngeal cartilages
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thyroid-largest, forms anterior and lateral walls of larynx (adams apple)
cricoid-inferior to thyroid cartilage both protect glottis and entrance to trachea |
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epiglottis
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superior to glottis, supported by epiglottal cartilage-folds over glottis during swallowing
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paired laryngeal cartilages
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2 arytenoid, 2 corniculate, 2 cuneiform
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laryngeal ligaments
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intrinsic-bind all 9 cartilages
extrinsic-attach larynx to hyoid and trachea vocal-between thyroid and arytenoid cartilages vestibular-between thyroid and arytenoid cartilages |
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vestibular folds
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false vocal cords, mucosal folds in the laryngeal wall that have a protective function
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vocal folds
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true vocal cords-folds in laryngeal wall that produce sound
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laryngeal musculature
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intrinsic-regulate tension in vocal folds, open/close glottis
extrinsic-position/stabilize larynx |
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trachea
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windpipe-begins anterior to C6 continues to T5 where it branches into right/left primary bronchi
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connective tissue of the trachea
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lamina propria that overlays the epithelium
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anular ligaments
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bind the 15-20 c-shaped tracheal cartilages to one another
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primary bronchi
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extrapulmonary structures (located outside lungs), right and left distal branches of trachea
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carina
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ridge on the base of the trachea that marks its division into the primary bronchi
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hilus
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region of the lung where right and left primary bronchi enter (as well as blood vessels)
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regions of the lungs
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apex-conical tip that points superiorly
base-concave inferior portion that rests on the superior surface of the diaphragm |
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lobes of the lung
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superior, middle, inferior in right lung
superior and inferior in the left lung |
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horizontal fissure
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separates superior and middle lobes of the right lung
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oblique fissure
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one separates superior and inferior lobes of the right lung, another separates same in the left lung
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cardiac notch
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concavity formed from position of heart in the mediastinum
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lung surfaces
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costal surface-anterior surface,faces ribs
mediastinal surface-medial surface, hilus located on it diaphragmatic surface-inferior surface that faces diaphragm |
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bronchopulmonary segments
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segments of lungs that are smaller than lobes and are associated with a single tertiary bronchus
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bronchial tree
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formed from the primary bronchi and their branches
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primary bronchi
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extrapulmonary structures that divide into smaller branches, called intrapulmonary bronchi, as they enter the lung
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right primary bronchus
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divides into 3 secondary bronchi:superior, middle, inferior lobar bronchi
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left primary bronchus
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divides into 2 secondary bronchi:superior and inferior lobar bronchi
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tertiary bronchi
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aka segmental
serve each bronchopulmonary segment (walls of secondary and tertiary bronchi contain cartilage plates) |
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terminal bronchioles
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divisions of tertiary bronchi, walls lack cartilage support, made of smooth muscle
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sympathetic stimulation of the bronchioles
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leads to enlargement of the airway, or bronchodilation
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parasympathetic stimulation of the bronchioles
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leads to bronchoconstriction
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respiratory bronchioles
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branches of the terminal bronchioles that deliver air to each individual lung lobule
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alveolar ducts
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passageways that connect respiratory bronchioles to alveoli
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alveolar sacs
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terminal ends of alveolar ducts that connect several alveoli
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alveoli
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pockets at the end of the bronchial tree where gas exchange with the blood occurs-lined with simple squamous epithelium called type 1 cells, or respiratory epitheliocytes
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septal cells
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type II cells or surfactant cells-scattered among the epithelium and secrete surfactant, an oily secretion that reduces surface tension in the fluid coating alveolar surface
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alveolar macrophages
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phagocytic cells within the epithelium
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respiratory membrane
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area of gas exchange, formed fusion of the basement membrane of alveolar epithelium and adjacent capillaries
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where do the pulmonary arteries enter the lung?
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at the hilus where they branch with the bronchi as they approach each lobule
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blood supply to each lobule
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each lobule receives an arteriole, venule, and a network of capillaries that surrounds each alveolus
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alveolar capillaries
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provide a mechanism for gas exchange and are primary source of ACE, which converts circulating angiotensin I to angiotensin II
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angiotensin II
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a hormone involved with regulation of blood volume and pressure
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pulmonary ventilation
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breathing-movement of air into and out of bronchial tree
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alveolar ventilation
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prevents build up of CO2 and ensures continuous supply of O2
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respiratory muscles
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diaphragm, external intercostals, internal intercostals, accessory muscles
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diaphragm
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contraction increases the volume of the thoracic cavity by flattening its floor, this draws air into the lungs (inhalation)
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external intercostals
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muscles that assist by elevating ribs during inhalation
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internal intercostals
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muscles that depress the ribs and reduce the width of the thoracic cavity (exhalation)
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accessory respiratory muscles
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active when the depth and frequency of respiration must be increased
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eupnea
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quiet, normal breathing that involves muscular contractions, but expiration is passive
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diaphragmatic breathing
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deep breathing, contraction of the diaphragm provides necessary change in thoracic volume drawing in air, exhalation occurs when diaphragm relaxes
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costal breathing
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shallow breathing-thoracic volume changes because rib cage changes shape, contraction of external intercostal muscles elevate ribs and enlarges thoracic cavity-inhalation, muscles relax-exhalation
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hypernea
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forced breathing that involves active inhalation and exhalation, accessory muscles assist (heavy exercise)
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breathing control in the brain
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respiratory control centers are located in the pons and medulla oblongata
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functions of the digestive system
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ingestion, mechanical processing , digestion, secretion, absorption, compaction, excretion
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4 major layers of the digestive tract
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mucosa, submucosa, muscularis externa, serosa
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mucosa
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inner lining of digestive tract made up of epithelium containing plicae, areolar CT called lamina propria that is covered by the muscularis mucosae-layer of smooth muscle and elastic fibers
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plicae
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tranverse or longitudinal folds that increase surface area for absorption in digestive tract
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muscularis mucosae
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outermost layer of the mucosa, two concentric layers-circular inner layer that encircles lumen and longitudinal outer layer with parallel fibers
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submucosa
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layer of areolar tissue that surrounds the muscularis mucosae-contains blood vessels, lymphatics, exocrine glands that secrete buffers and enzymes
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submucosal plexus
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network of fibers and scattered neuron cell bodies that innervate the mucosa
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muscularis externa
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layer of smooth muscle that surrounds the submucosa and contains circular (inner) and longitudinal (outer) muscle layers
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myenteric plexus
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network of autonomic ganglia and fibers between the circular and longitudinal layers
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parasympathetic stimulation of myenteric plexus
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increases muscular tone and stimulates contraction
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sympathetic stimulation of myenteric plexus
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promotes inhibition of muscular activity and relaxation
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sphincters
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thickened areas of circular muscle that prevent material from moving along the tract at an inappropriate time or in the wrong direction
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serosa
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serous membrane that covers the muscularis externa, located in most regions of digestive tract
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adventitia
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dense network of collagen fibers that covers the muscularis externa of the oral cavity, pharynx, esophagus, and rectum, instead of a serosa layer
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accessory structures of the digestive system
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teeth, tongue, liver, gallbladder, pancreas, salivary gland
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organs and structures of the digestive tract
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pharynx, esophagus, stomach, small intestine, large intestine, oral cavity
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contractile proteins of smooth muscle
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do not form sarcomeres but are capable of strong contraction
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plasticity
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ability of smooth muscle cells to stretch and adapt to a new length, then contract again
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2 types of movement in digestive tract
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peristalsis and segmentation
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peristalsis
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contractions of the muscularis externa that propel material through the digestive tract
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bolus
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small oval mass of food
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peristaltic wave
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event where the circular muscles contract behind digestive contents, then longitudinal muscles contract shortening adjacent segements, finally a 2nd wave of contraction in circular muscles forces the material in the desired direction
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segmentation
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movements in areas of the small intestine that churn digestive materials, mix the contents with intestinal secretions, but produce no net movement
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mesenteries
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fused, double sheets of peritoneal membrane that stabilize attached organs
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greater omentum
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"fatty apron" double layer of mesentery that hangs anteriorly from the stomach
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lesser omentum
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mesentery that runs between the stomach and liver
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mesentery proper
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suspends and wraps the small intestine, provides stability but permits a degree of independent movement
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mesocolon
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suspends and wraps the colon and includes the transverse and sigmoid mesocolon
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functions of oral cavity
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analysis of material before swallowing, mechanical processing with teeth etc, lubrication by mixing mucous and salivary secretions, limited digestion of carbs by salivary enzymes
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buccal cavity
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lined with oral mucosa of stratified squamous epithelium that does not keratinize and protects the mouth from abrasion
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what supports the oral cavity mucosa
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buccal fat pads and buccinator muscle
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vestibule of oral cavity
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space between cheeks, lips and teeth
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what forms the roof of the oral cavity?
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hard and soft palates
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uvula
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structure that dangles from the center of the soft palate
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what organ forms the floor of the oral cavity?
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tongue
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parts of the tongue
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body-anterior oral portion
root-point of attachment dorsum-contains numerous fine projections called papillae frenulum-thin fold of mucus membrane that connects the tongue to the mucosa of the oral floor |
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muscles of the tongue
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intrinsic muscles within tongue and extrinsic muscles outside of tongue
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3 pairs of salivary glands
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parotid, sublingual, submandibular
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parotid glands
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largest salivary glands, on lateral side of face anterior to ear, ducts drain into vestibule near 2nd upper molar
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sublingual glands
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salivary glands that are covered by the mucous membrane of the floor of the mouth, ducts drain near lingual frenulum
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submandibular glands
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located near the medial surface of mandible, ducts drain on either side of the lingual frenulum
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saliva
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70% submandibular, 25% parotid, 5% sublingual, contains salivary amylase to begin carb digestion, mucins that are glycoproteins for lubrication
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structure of teeth
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inner matrix dentin surrounded by crystals called enamel, pulp cavity, root canal, apical foramen, periodontal ligament, crown, neck, gingival sulcus
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dentin
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mineral matrix in tooth, covered by densely packed calcium crystals
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pulp cavity
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spongy, highly vascular hollow inside of a tooth that contains blood vessels and nerves
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root canal
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narrow tunnel located at the base, or root of the tooth
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apical foramen
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opening into root through which blood vessels and nerves enter
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periodontal ligament
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collagen fibers anchor the tooth to its bony socket
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crown
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exposed surface of the tooth
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neck of tooth
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marks the boundary between the root and the crown
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gingival sulcus
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where gum and tooth meet
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types of teeth
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8 incisor, 4 cuspids, 8 bicuspids, 12 molars
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dental succession
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deciduous-(primary, baby, milk) 20 teeth replaced by
permanent-(secondary) 32 teeth |
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3 phases of swallowing
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buccal, pharyngeal, esophageal
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buccal phase of swallowing
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compression of bolus against hard palate, followed by retraction of tongue forcing bolus into pharynx and elevating soft palate. voluntary until enters oropharynx
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pharyngeal phase of swallowing
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when bolus touches posterior pharyngeal wall the larynx elevates and the epiglottis folds pushing the bolus towards the esophagus
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esophageal phase of swallowing
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upper esophageal sphincter opens, peristalsis begins and lower esophageal sphincter opens
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esophagus
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transports food and liquids to the stomach, folds run length to allow expansion, no serosa, adventitia anchors esophagus in position against dorsal body wall
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stomach
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j-shaped organ that occupies the left hypochondriac, epigastric, and portions of the umbilical region of the abdominal cavity
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chyme
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semi-fluid mixture of ingested food and digestive secretions that is found in stomach
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anatomy of stomach
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lesser curvature-medial surface,greater curvature-lateral surface,rugae, regions:cardia,fundus,body,pylorus
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cardia region of stomach
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located under the heart
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cardiac orifice
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opening connected with the esophageal lumen
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fundus of stomach
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bulge above the esophageal opening that contacts the diaphragm
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body of stomach
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largest region, functions as a mixing tank for ingested food and gastric secretions
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pylorus
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inferior end that terminates at the muscular pyloric sphincter, which regulates the release of chyme into the first portion of the small intestine
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rugae of the stomach
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longitudinal folds of the stomach mucosa that permit expansion of the gastric lumen
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mesenteries associated with stomach
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greater and lesser omentum
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musculature of the stomach
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muscularis mucosae and muscularis externa contain an extra layer-outer longitudinal, middle circular, and inner oblique for added strength
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lining of stomach
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simple columnar epithelium forms a secretory sheet
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gastric pits
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depressions that open into the gastric surface, mucous cells at the base of each pit divide to replace superficial cells shed into chyme
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gastric glands
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simple branched tubular glands found in the underlying lamina propria
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3 types of cells found in gastric glands
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parietal, chief, and enteroendocrine
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parietal cells
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secrete HCl to kill micoorganisms, break down cell walls of food, and activate chief cells, and secrete intrinsic factor that facilitates absorption of vitamin b12
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chief cells
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secrete pepsinogen the inactive form that is converted by acids to pepsin, and secretes rennin and gastric lipase that are important for newborn milk digestion
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enterendocrine cells
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G cells=most abundant, secrete gastrin-hormone that stimulates the activity of parietal and chief cells and promotes smooth muscle activity in stomach, released when food enters stomach
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regulation of stomach
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CNS,ANS,vagus nerve, celiac plexus, hormones released by small intestine via stimulation by liver and pancreas, parasympathetic stimulates gastric juice production, sympathetic inhibits gastric secretions
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hormones that regulate the stomach
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cholecystokinin and secretin
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small intestine
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plays the primary (90%) role in digestion and absorption of nutrients, in all abdominal regions but left hypochondriac and epigastric
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plicae circularis
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transverse folds of the intestinal lining that function to increase surface area
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regions of the small intestine
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duodenum, jejunum, ileum
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duodenum
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retroperitoneal, c-shaped, shortest and widest portion connected to the pylorus of the stomach that functions as a mixing bowl that receives chyme from the stomach and digestive enzymes from the pancreas and liver
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pyloric sphincter
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guards the connection of the pylorus and duodenum which functions to prevent backflow
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jejunum
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second portion of the small intestine where the bulk of chemical digestion and nutrient absorption occurs
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duodenojejunal flexure
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curve that marks the point where the duodenum becomes the jejunum
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ileum
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3rd and final portion of the small intestine that functions primarily for absorption
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ileocecal valve
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junction between large and small intestines, controls the flow of material
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duodenum
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no supporting mesentery because it is retroperitoneal it is fixed in position between L1 and L4
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what supports the jejunum and ileum?
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supported by the mesentery proper
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intestinal villi
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fingerlike projections formed by the mucosa, covered by simple columnar epithelium
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microvilli
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sub-microscopic size projections on single cells of villi. brush boarder appearance
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intestinal crypts
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pockets at the base of each villus that extend deep into the underlying lamina propria
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duodenal submucosal glands
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aka brunner's glands-produce mucus that protects the epithelium from the acid chyme arriving from the stomach and contains buffers that help elevate the pH of chyme
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duodenal papilla
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point where the common bile duct of the liver and gallbladder and the pancreatic duct from the pancreas come together
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duodenal ampulla
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entry point for the duodenal papilla duct
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function of the duodenum
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mixing and churning
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function of the jejunum and ileum
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absorption
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aggregate lymphoid nodules
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peyer's patches-lymphoid centers near the entrance to the large intestine, contains numbers of potentially harmful bacteria
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regulation of the small intestine
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nervous system-local reflexes, parasympathetic stimulates secretions, sympathetic inhibits secretions, hormones-cholecystokinin and secretin regulate and coordinate secretory activities of stomach, duodenum, liver, pancreas
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large intestine
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colon-inferior to stomach and liver, reabsorbs water and electrolytes, compacts contents to feces, absorbs vitamins produced by bacteria, stores fecal material
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cecum
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expanded pouch at proximal end of colon
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ileal papilla
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opening of ileum into the cecum
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ileocecal valve
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covers ileal papilla and regulates the passage of material
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vermiform appendix
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lymphoid tissue attached to surface of cecum and suspended by a band of mesentery called mesoappendix
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haustra
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pouches along the walls of the colon that permit considerable distension and elongation created by muscle tone
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taeniae coli
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3 separate longitudinal ribbons of smooth muscle
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epiploic appendages
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fatty appendages-fat sacs of the serosa of the colon
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ascending colon
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retroperitoneal structure with no mesentery associated
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right colic flexure
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hepatic flexure-point where the ascending colon meets the liver and turns right
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transverse colon
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supported by the transverse mesocolon and separated from the anterior abdominal wall by the greater omentum
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gastrocolic ligament
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attaches the transverse colon to the greater curvature of the stomach
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left colic flexure
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aka splenic flexure-point where the transverse colon makes a right angle and bends towards the spleen
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descending colon
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begins at the left colic flexure and runs down the left side of the abdomen until it begins to curve into the sigmoid flexure
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sigmoid colon
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s-shaped distal region of the colon that lies posterior to the bladder and empties into the rectum, suspended by the sigmoid mesocolon
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rectum
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expandable organ for temporary storage of fecal matter
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anal canal
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contains small logitudinal folds called anal columns
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anus
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terminal end of the anal canal
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internal sphincter
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involuntary, formed from the circular muscle layer of the muscularis externa in this region
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external sphincter
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voluntary skeletal muscle sphincter that encircles the distal portion of the anal canal
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histology of the large intestine
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large diameter, thinner walls that small intestine
lacks villi more abundant goblet cells |
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regulation of large intestine
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haustral churning-segmentation movements of the LI
mass movements-periodic peristalsis stimulated by distension of the stomach and duodenum |
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accessory digestive organs
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produce and store enzymes and buffers that are essential to normal digestive function
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liver
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largest visceral organ that provides metabolic regulation, hematological regulation, synthesis and secretion of bile
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metabolic regulation by the liver
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all blood leaving the absorptive surfaces of digestive tract enter the hepatic portal system and nutrients and toxins can be extracted from blood before it enters systemic circulation
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synthesis and secretion of bile
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bile is stored in the gallbladder and excreted into the lumen of the duodenum where bile salts associate with lipids in chyme so enzymes can break them down into fatty acids
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lobes of the liver
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right, left, quadrate, caudate
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falciform ligament
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marks the division between the right and left lobes
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round ligament
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aka ligamentum teres-in the liver-fibrous band that marks the degenerated umbilical vein
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coronary ligament
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between liver and diaphragm
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hilus of the liver
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porta hepatis-underside entry point for blood vessels and ducts
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basic functional units of the liver
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liver lobules
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hepatocytes
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liver cells-arranged around a central vein which creates a series of irregular plates inside each lobule
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kupffer cells
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phagocytic cells found in the lobule lining
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composition of bile
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water, minor amts of irons, bilirubin and bile salts
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canaliculi
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passageways between liver cells that extend outward through each liver lobule and eventually connect with bile ducts by ductules
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right and left hepatic ducts
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collect bile from ducts of the liver lobes
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common hepatic duct
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formed from the unity of the right and left hepatic ducts, from it bile enters the gallbladder via the cystic duct or enters the duodenum
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common bile duct
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common hepatic duct and cystic duct-empties into duodenum at papilla
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gallbladder
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hollow, pear shaped muscular organ that stores and concentrates bile before its secretion into duodenum
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pancreas
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retroperitoneal organ that extends laterally from the duodenum towards the spleen
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structure of the pancreas
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head-near duodenum
body tail-near spleen |
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function of the pancreas
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exocrine organ producing digestive enzymes and buffers, also has endocrine functions
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pancreatic duct
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delivers pancreatic secretions to the duodenal ampulla
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histology of the pancreas
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lumpy nodular texture, lobules are partitioned by CT, acini produce pancreatic juice (mix of water, ion and pancreatic digestive enzymes)
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pancreatic enzymes
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lipases, carbohydrases, nucleases, proteolytic enzymes including proteinases and peptidases
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regulation of pancreas
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secretion of juices in response to hormonal instruction from the duodenum. secretin and cholecystokinin
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nephron
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basic structural and functional unit of the kidney
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proximal convoluted tubule
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reabsorbs water, ions, all organic nutrients
part of nephron |
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renal corpuscle
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produces filtrate, filters out stuff the body still wants so this filtrate still contains things the body wants. filtrate=tubular fluid
part of nephron |
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distal convoluted tubule
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part of nephron-secretes ions, acids, drugs, toxins, variable reabsorption under hormonal control
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connecting tubules and collecting duct
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part of nephron-variable reabsorption of H2O and reabsorption/secretion of sodium, potassium, hydrogen, bicarbonate ion
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papillary duct
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part of nephron-delivers urine to minor calyx
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loop of henle
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part of nephron-further reabsorption of water in the descending limb, and Na+ and Cl- in ascending limb
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micturition
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urination
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urinary system
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kidneys and urinary tract (ureters, urinary bladder, urethra)
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right kidney surface features
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anterior surface is covered by the liver, hepatic flexure of the colon and the duodenum. superior surface is capped by adrenal gland
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left kidney surface features
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anterior surface is covered by the spleen, stomach, pancreas, jejunum, and splenic flexure of the colon. superior surface is capped by adrenal gland
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3 concentric layers of CT that protect the kidney
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renal capsule-fibrous tunic-layer of collagen fibers
adipose capsule-perirenal fat-layer of adipose that surrounds the renal capsule renal fascia-superficial layer of collagen that anchors kidney to surroundings |
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hilus of kidney
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opening on medial side that marks the entry for renal artery and exit for renal vein and ureter
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renal sinus
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region inside the kidney where renal blood vessels and nerves branch
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cortex of kidney
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reddish-brown, granular outer layer
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medulla of kidney
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internal to the cortex and consists of 6-18 distinct conical structures, called renal pyramids
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renal papilla
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tip of each renal pyramid
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renal columns
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bands of cortical tissue that separate each renal pyramid
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renal lobe
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consists of renal pyramid, overlying area of renal cortex, adjacent tissues of the renal columns-urine produced here
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minor calyx
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cup shaped region inferior to each renal papilla-collects discharged urine
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major calyx
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formed from the merging of 4-5 minor calyces
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renal pelvis
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large, funnel-shaped chamber formed from the merging of the major calyces
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blood supply of kidney
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receives 20-25% of total cardiac output, renal artery and renal vein
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glomerulus
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part of nephron-capillary network where filtration occurs
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afferent arteriole of kidney
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brings blood to the glomerulus
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efferent arteriole of kidney
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carries blood away from glomerulus
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glomerular filtrate
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protein-free solution produced from filtration across the glomerulus
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cortical nephrons
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located almost entirely within cortex-85%
|
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juxtamedullary nephrons
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located closer to the medulla-15%
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visceral (glomerular) epithelium
|
large cells called podocytes that wrap around glomerular capillaries
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capsular space
|
separates the parietal and visceral epithelium
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vascular pole
|
marks the connection of the parietal and visceral epithelium and the connection of the glomerular capillaries to the bloodstream
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filtration
|
occurs as blood pressure forces fluid and dissolved solutes out of the glomerulus into the capsular space
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capillary endothelium
|
contains openings that are small enough to prevent passage of blood cells but are to large to restrict diffusion of solutes
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basement membrane of the nephrons
|
surrounds the capillary endothelium and has several times the density and thickness that is typical. called the "lamina densa" restricts passage of smaller plasma proteins, nutrients, ions
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filtration slits
|
narrow gaps that separate pedicles (processes of glomerular epithelium that wrap around basement membrane) and allow for only water with dissolved ions, small organic molecules, and few plasma proteins to pass
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lining of the PCT
|
(proximal convoluted tubule)-simple cuboidal epithelium with microvilli
|
|
descending limb of the loop of henle
|
travels in the medulla toward the renal pelvis
|
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ascending limb of the loop of henle
|
returns toward the cortex
|
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vasa recta
|
slender capillaries that absorb water from that flows out of the nephron from the loop of henle, returns it to general circulation
|
|
DCT versus PCT
|
DCT has smaller diameter, lacks microvilli, epithelial cells have distinct boundaries, function is secretion as opposed to absorption
|
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juxtaglomerular apparatus
|
endocrine structure formed from structures of the DCT that secretes 2 hormones, renin and erythropoietin-elevate blood volume, hemoglobin levels, blood pressure, restore normal rate of filtration production
|
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collecting system of the kidney
|
connecting tubule carries filtrate from DCT to collecting duct which leaves the cortex and descends into the medulla toward a papillary duct that drains into the renal pelves
|
|
transitional epithelium
|
tolerates cycles of distension and contraction, found in minor and major calyces, renal pelvis, ureters,urinary bladder, proximal portion of urethra
|
|
ureters
|
paired muscular tubes that begin as continuation of renal pelvis, exit kidney via hilus, extend approx. 12 inches to urinary bladder
|
|
walls of the ureters
|
inner mucosa-lined by transitional epithelium
middle muscular layer of longitudinal (inner) and circular (outer) smooth muscle outer CT layer is continuous with fibrous renal capsule |
|
male urinary bladder
|
base lies between rectum and symphysis pubis
|
|
female urinary bladder
|
base sits inferior to the uterus and anterior to vagina
|
|
median umbilical ligament
|
aka urachus-peritoneal fold that extends from the anterior and superior border to the umbilicus
|
|
lateral umbilical ligaments
|
peritoneal folds that pass along the sides of the bladder to reach the umbilicus
|
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trigone
|
triangular area bounded by ureteral openings and entrance to the urethra-lacks rugae, smooth and thick, funnel that channels urine into the urethra when bladder contracts
|
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neck of bladder
|
region surrounding the urethral opening
|
|
internal urethral sphincter
|
smooth muscle that provides involuntary control over the discharge of urine from the bladder-autonomic control
|
|
detrusor muscle
|
formed from the longitudinal and smooth muscle layers of the urinary bladder-contraction compresses the bladder and expels its contents
|
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walls of urinary bladder
|
mucosa,submucosa,muscularis, serosa
|
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female urethra
|
1-1.5 inches, extends from bladder to vestibule
|
|
external urethral meatus
|
external opening situated near the anterior wall of the vagina
|
|
male urethra
|
7-8 inches, 3 portions-prostatic urethra passes through prostate-membranous urethra short and penetrates muscular floor of pelvic cavity-penile urethra distal segment extends from urogenital diaphragm to tip of penis
|
|
external urethral sphincter
|
circular band of skeletal muscle under voluntary control
|
|
histology of urethra
|
females-transitional epithelium near bladder, rest is stratified squamous
males-neck of bladder to external urethral meatus changes from transitional to pseudostratified columnar or columnar, then stratified squamous |
|
calcitrol
|
synthesized by the urinary system, hormone derivative of vitamin D3 that stimulates calcium ion absorption in the intestine
|