2012 Msi 3

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Compound Melanocytic Nevus

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Infantile Hemangioma

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Interdermal Melanocytic Nevus

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Junctional Melanocytic Nevus

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Seborrheic Keratosis

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Skin Tag

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Solar Lentigo

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Rash-Erythema-Multiforme

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Rash-Fixed-Drug-Eruption

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Rash-Morbilliform

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Rash-SJS-TEN

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Rash-Urticaria

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4 layers of Epidermis from in to out ?

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1) Basal layer 2)Stratum spinosum 3)Granular layer 4) Stratum Corneum

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What are the two tineas that can't be treated topically?

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1) Capitis 2) Onychomycosis (Unguium)

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What are the cellular components in Epidermis(3) ?

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1) Keratinocytes 2)Melanocytes 3)Langerhan cells

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What are the three genera of fungal infections?

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1) Microsporum 2) Trichophyton 3) Epidermophyton

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What are 2 layers of dermis in to out?

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1) Reticular 2)Papillary

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What are 3 adnexal structures of skin ?

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1) Sweat glands 2)Hair 3)Nails

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What are the 4 compoments released during early phase of hypersensitivity reaction?

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1) Vasoactive amines 2)Proteases 3)Prostaglandins 4)Leukotriens (LTB4)

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What are the cellular components in Dermis (3) ?

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1)Fibroblasts 2)Macrophage 3)Dermal dendritic cells

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Systematic treatment for Psoriasis?

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Acitretin (oral)

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Mostly in teens, mass of all types of acne, usually treated with roids

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Acne conglobata

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Most severe acne, explosive onset, with systemic symptoms - fever etc..., usually more neck

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Acne fulminans

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Acne from repetitive physical trauma

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Acne mechanica

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What type of herpies has short growth cycle, cytolytic, infect neurons?

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Alpha

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What is growing phase of hair called?

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Anagen

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Painful, shallow ulcers, trauma may precipitate, no fever, nodes not enlarged

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Aphthous Stomatitis

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What is a blood infection?

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Bacteremia

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Carcinoma that is pearly papule, has telangiectasia

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Basal Cell Carcinoma

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What type of herpies has long growth cycle, cytomegalic, infect glands and lymph?

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Beta

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Fluid filled, >1 cm dia.

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Bulla

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Yeast infection caused by oportunistic flora, usually in mouth, milkly lesions/discharge

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Candidiasis

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Anaerobic spore forming bacilli ?

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Clostridiums

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Red papule, enlarging lesion, multply in macrophages

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Cutaneous Leishmaniasis

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What is released during late phase of hypersensitivity reaction?

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Cytokines

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Why are anaerobes sensitive to oxygen?

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Due to lack of SOD (superoxide dismutase)

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What kind of streptococci is: PYR positive, varied hemolysis, Esculin hydrolyzation, Bile tolerant

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E. faecalis

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Fever, joint pain, raised plaque like rash with dusky centers, erythematous (target lesion), by nonspecific viral infection

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Erythema Multiforme

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hard, dark, plaque covering ulcer, tissue necrosis

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Eschar

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truma related to scratching or rubbing

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Excoriation

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"Slap" red cheeks, lace like rash, supresses RBC production, profound anemia in fetus causes highoutput heart failure, Usually in spring time

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Fifth Disease (Exanthem Infectiosum)

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What type of herpies has variable growth cycle, infects lymphoid?

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Gamma

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Flu like symptoms, rash evolves to pruritic, confluent 2mm papules,

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Gloves and Sock syndrome

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Dark urine, bright red sputum, Complement/Fc receptor mediated inflammation, noncollagenous protein in kidney targeted, type II

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Goodpasture's syndrome

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More common in summer, Vesciles on hands and feet, red spot rash, painful ulcers in oral cavity

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Hand-Foot-Mouth Syndrome (Usually Coxsackie virus A16)

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Fever, Oral ulcers, painful adenopathy,

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HSV 1 (herpes simplex gingivostomatitis)

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Golden crusts, caused by staph.,

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Impetigo

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What is last resort drug for acne and side effect?

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Isotertinoin, Teratogenic

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high fever >5 days, oral mucosal changes, cervical node (1) enlargement, swollen extremities, rash that starts to peel around nails, conjunctival injection, main concern aneurysms

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Kawasaki Disease

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Change in color of skin, flat, not palpable

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Macule

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Characterized by: Cough, coryza, conjuctivities, Koplik spots, fever for 3-5 days

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Measles (Rubeola)

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Tiny purple spot (petechiae) (don't blanch with pressure), fever, normal WBC, hypotension, DIC

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Meningococcemia (Neisseria meningitidis)

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Usually raised, FIRM lesion, <1cm

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Nodule

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Superficial, palpable, raised lesion, distinct boarders, >1cm

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Papule

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What are the strains of lice called?

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Pediculosis / Pthirus

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Which type of lice effect eyebrows?

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Pediculosis pubis

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What fungus looks like spaghetti and meatballs in micropscopy?

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Pityriasis versicolor (P Versicolor)

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Solid, raised, flat topped lesion, >1cm, plateau like

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Plaque

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106F fever, child looks good, suboccipital lymph enlargement, Febrile seizure, salmon rash

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Roseola Infantum (Exanthem Subitum), HHV 6

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Blueberry muffins, Deafness, VSD, cataracts, Cognitive delay, Posterior auricular adenopathy

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Rubella

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What kind of streptococci is: B-hemolytic, Bacitracin sensitive, Hippurate hydrolyzation, Hippurate hydrolyzation, CAMP test positive

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S. agalactiae

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What is most important staphylococci?

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S. aureous

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What kind of streptococci is: a-hemolytic, Optochin resistant, Lysed by bile

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S. pneuomoniae

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What kind of streptococci is: B-hemolytic, Bacitracin sensitive, Pyrrolidonyl arylamidase positive (PYR)

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S. pyogenes (GAS)

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If see burrows and itching in skin what does it point to?

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Scabies

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Skin lesion that is "stuck-on" and "greasy", darker, common and hereditary

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Seborrheic Keratosis

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What is a systemic infection?

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Septicemia

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Trans by skin trauma or inhalation, frequent in garders, chronic cutaneous infections

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Sporotrichosis

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Carcinoma with scaling plaque

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Squamous cell carcinoma

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Skin painful to touch, signs of peeling, sunburn like

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Staphylococal scalded skin syndrome

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Bunch of grapes, Gram +, able to grow in high salt, on skin and mucous membranes

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Staphylococcus

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Acne: Lesions are all at same stage of development, mainly on trunk and shoulders

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Steroid acne

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Lack of rhinorrhea, Lack of conjunctivitis, lack of cough, Painful nodes, strawberry tongue, halitosis

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Streptococcal (Scarlet Fever)

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Grows in chains, Catalase NEGATIVE, Gram +,

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Streptococci

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What is the most common cause of Tinea in adults, except capitis?

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T Rubrum (Tricophyton Rubrum), Capitis = T. Tonsurans

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permanently dilatated superficial blood vessels

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Telangiectasia

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What type of reaction is urticaria?

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Type 1

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What type of reaction is fixed drug eruption?

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Type 2

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What type of reaction is Morbilliform?

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Type 4

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What type of reaction is Erythema multiforme?

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Type 4

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Rash spreads rapidly over trunck, Vesicles, drying lesion, pruritic rash, >500 lesions

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Varicella (Chicken pox)

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Fluid filled, <1 cm dia.

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Vesicle

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What kind of streptococci is: a-hemolytic, Optochin resistant, NOT lysed in bile

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Viridans S.

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Hyperpigmented skin, fever, hepatosplenomegaly, pancytopenia

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Visceral Leishmania

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Upper dermis adema, hive

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Wheal

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How does one diagnose Tineas and Pityriasis versicolor ?

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With Potassium Hydroxide (KOH)

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What does KOH show for Candidiasis ?

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Yeast and Pseudohyphae

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Type 2, antibody autoimmune that stimulates TSH receptor without hormone,

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Graves disease

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Type 2, antibody autoimmune that inhibits receptor without hormone,

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Myaethenia Gravis