Literature Review
The Incredible Hulk The incredible hulk is a fictional comic book character who was created in the 1962 by comic book authors Stan Lee and Jack Kirby (Capitanio, 2010). The comic is centered on a scientist named Bruce Banner who was exposed to sever amounts of gamma radiation. The radiation altered his genetic make-up creating an alter ego known as the Hulk. The comic book character The Hulk is loosely based on the combination of Dr. Jekyll and Mr. Hyde and Shelley’s Frankenstein (Capitanio, 2010). When Dr. Banner experiences an increase in blood pressure—normally due to becoming angry—his alternate personality emerges. The character The Hulk is a nearly indestructible human like creature with green skin and a simpler mind …show more content…
Epigenetics refers to the chemical changes that occur in the genome (Banovich et al., 2014). The process of epigenetic modification occurs in the gene themselves and must be a heritable trait. The changes typically are considered to only affect the genome as a whole and not the DNA structure itself. The modification process
typically occurs in the generation and development stage or as a response to environmental factors. According to the article, the study of epigenetics applies to a small change, or several small changes, in a gene however it can be applied to the overall genome. The key player in the study of epigenetic modification is methylation (Banovich et al., 2014). Methylation is the process by which genes are regulated. When methylation occurs a methyl group is added to a specified nucleotide section. This process occurs at the varying stages of genetic modification, however a large part is because of environmental stimuli. According to Roy and Kundu (2014), the fate of a cell has more than one possibility. Gene regulation has the potential to create multistage existence based on the current genome status, and has the potential to be rewritten as another form or expression. How the cells determine change and at what point the transition is halted one of the biggest studies taking place in biological …show more content…
Degner, John D. Blischak, Julien Roux, Jonathan K. Pritchard, and Yoav Gilad. “Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels.” PLoS Genetics 10, no. 9 (September 2014): 1–12. doi:10.1371/journal.pgen.1004663.
Capitanio, Adam. “‘The Jekyll and Hyde of the Atomic Age’: The Incredible Hulk as the Ambiguous Embodiment of Nuclear Power.” Journal of Popular Culture 43, no. 2 (April 2010): 249–70. doi:10.1111/j.1540-5931.2010.00740.x.
Henner, W. D., S. M. Grunberg, and W. A. Haseltine. “Sites and Structure of Gamma Radiation-Induced DNA Strand Breaks.” Journal of Biological Chemistry 257, no. 19 (October 10, 1982): 11750–54.
Roy, Siddhartha, and Tapas K. Kundu. “Gene Regulatory Networks and Epigenetic Modifications in Cell Differentiation.” IUBMB Life 66, no. 2 (February 2014): 100–109. doi:10.1002/iub.1249.
Nakagami, Tatsuyoshi, Koji Toyomura, Taroh Kinoshita, and Seiji Morisawa. “A Beneficial Role of Bile Pigments as an Endogenous Tissue Protector: Anti-Complement Effects of Biliverdin and Conjugated Bilirubin.” Biochimica et Biophysica Acta (BBA) - General Subjects 1158, no. 2 (October 3, 1993): 189–93.
The Incredible Hulk The incredible hulk is a fictional comic book character who was created in the 1962 by comic book authors Stan Lee and Jack Kirby (Capitanio, 2010). The comic is centered on a scientist named Bruce Banner who was exposed to sever amounts of gamma radiation. The radiation altered his genetic make-up creating an alter ego known as the Hulk. The comic book character The Hulk is loosely based on the combination of Dr. Jekyll and Mr. Hyde and Shelley’s Frankenstein (Capitanio, 2010). When Dr. Banner experiences an increase in blood pressure—normally due to becoming angry—his alternate personality emerges. The character The Hulk is a nearly indestructible human like creature with green skin and a simpler mind …show more content…
Epigenetics refers to the chemical changes that occur in the genome (Banovich et al., 2014). The process of epigenetic modification occurs in the gene themselves and must be a heritable trait. The changes typically are considered to only affect the genome as a whole and not the DNA structure itself. The modification process
typically occurs in the generation and development stage or as a response to environmental factors. According to the article, the study of epigenetics applies to a small change, or several small changes, in a gene however it can be applied to the overall genome. The key player in the study of epigenetic modification is methylation (Banovich et al., 2014). Methylation is the process by which genes are regulated. When methylation occurs a methyl group is added to a specified nucleotide section. This process occurs at the varying stages of genetic modification, however a large part is because of environmental stimuli. According to Roy and Kundu (2014), the fate of a cell has more than one possibility. Gene regulation has the potential to create multistage existence based on the current genome status, and has the potential to be rewritten as another form or expression. How the cells determine change and at what point the transition is halted one of the biggest studies taking place in biological …show more content…
Degner, John D. Blischak, Julien Roux, Jonathan K. Pritchard, and Yoav Gilad. “Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels.” PLoS Genetics 10, no. 9 (September 2014): 1–12. doi:10.1371/journal.pgen.1004663.
Capitanio, Adam. “‘The Jekyll and Hyde of the Atomic Age’: The Incredible Hulk as the Ambiguous Embodiment of Nuclear Power.” Journal of Popular Culture 43, no. 2 (April 2010): 249–70. doi:10.1111/j.1540-5931.2010.00740.x.
Henner, W. D., S. M. Grunberg, and W. A. Haseltine. “Sites and Structure of Gamma Radiation-Induced DNA Strand Breaks.” Journal of Biological Chemistry 257, no. 19 (October 10, 1982): 11750–54.
Roy, Siddhartha, and Tapas K. Kundu. “Gene Regulatory Networks and Epigenetic Modifications in Cell Differentiation.” IUBMB Life 66, no. 2 (February 2014): 100–109. doi:10.1002/iub.1249.
Nakagami, Tatsuyoshi, Koji Toyomura, Taroh Kinoshita, and Seiji Morisawa. “A Beneficial Role of Bile Pigments as an Endogenous Tissue Protector: Anti-Complement Effects of Biliverdin and Conjugated Bilirubin.” Biochimica et Biophysica Acta (BBA) - General Subjects 1158, no. 2 (October 3, 1993): 189–93.