Transfusion : Transfusion Related Acute Lung Injury Essay example

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Running head: TRANSFUSION 1 TRANSFUSION 2 Transfusion-related acute lung injury (TRALI) is an under-reported, life-threatening complication of blood component transfusion due to the misinterpretation of symptoms, unfamiliarity of causes, and delay of standardizing methods of prevention. According to Mazzei, Popovsky, & Kopko (2008, 734), TRALI is characterized by symptoms indistinguishable from acute respiratory distress syndrome (ARDS) and usually consists of some or all of the following symptoms: Cyanosis (bluish color of skin), dyspnea (difficulty breathing), hypotension (low blood pressure), hypoxemia (low oxygen in blood), and sometimes fever. Bux (2005, 2) agrees that x-rays and other radiological testing show patchy infiltrates in the lungs and eventually “white out” on both sides or bilaterally in both lungs. According to Davenport (2011, 771), TRALI has a wide range of severity different for each patient potentially leading to the misidentification or misdiagnosis of patients any hypotension and fever are present they are usually mild. TRALI is often characterized as non-cardiogenic lung edema occurring within 6 hours of transfusion of blood components. Symptoms typically occur within the first 1 to 2 hours completion of transfusion and are transient or short lasting and resolve after 72 hours unlike other lung injuries. (Silliman, Ambruso, & Boshkov, 2005, 2266). If the symptoms do not resolve within the…

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