How Gene Doping Is Used By The Wada ( World Anti Doping Agency )

888 Words Nov 6th, 2014 4 Pages
Matthew Wood
Rough Draft Gene doping is defined as “The transfer of polymers of nucleic acids or nucleic acid analogues” by the WADA (World Anti-Doping Agency). Essentially gene doping is modification of a person’s genes in order to improve how they perform. This can be done several ways, however the most common method is the use of a vector. The gene that is to be inserted into the host is placed inside the capsule of a virus. The virus is able to spread throughout the tissue to be effected and injects its DNA into individual host cells. The host cells can then update certain DNA fragments and incorporate them into their own DNA sequence. This can lead to a downstream effect of protein or hormone production among other possibilities. These products produced by the affected cells have the possibility to influence how well a host can perform tasks such as improving endurance or stress management. This differs significantly from other types of doping such as blood doping due to its extended longevity. Blood doping, removal of blood and reinjection after blood loss has been compensated for in order to increase erythrocyte levels, is a temporary “fix” and over time the erythrocyte levels will decrease back to normal levels. Gene doping will affect its host much longer and may not revert back to “normal” for over a year (gene engineering article). Gene doping does not lose its effectiveness as the injected cells slowly die out. In fact the exact opposite is true. In…

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