Dopamine Influence

Improved Essays
Drug abuse is one of the environmental factors that contribute to schizophrenia. According to the National Institute on Drug Abuse, “Most drugs of abuse directly or indirectly target the brain’s reward system by flooding the circuit with dopamine.” Drugs such as cannabis and heroine can activate neurons because of their chemical structures resembling that of the natural neurotransmitter, dopamine, as was discussed earlier. These drugs can release two to ten times the amount of dopamine than that of the natural rewards of dopamine. The affects is euphoria of the reward center clearly being more potent and lasting longer. From this excess presence of dopamine, the brain adjusts by producing less of the neurotransmitter as well as the receptors (receptors are specialized sites on the receiving neuron where the neurotransmitter attaches to relay appropriate messages). …show more content…
Therefore in order to feel pleasure again, the drug user must take more drugs repeatedly in order to bring the dopamine function back up to normal. Due to the imbalance drugs can create on dopamine levels in the brain, along with other neurotransmitters, it is clear to see how drugs can influence the progression of schizophrenia in most cases. According to Atkinson, author of the article, “Cannabis use ‘trigger for schizophrenia’”, a study was performed in Germany where a group of 2,500 subjects, aged 14-24, who smoked cannabis were studied for four years. They found adolescents who smoked cannabis slightly increased the risk of developing signs of psychosis later on in life, increasing from 16-25%. They also discovered that those predisposed to psychosis, who showed signs of disturbed thought processes, increased their chance of developing psychosis by 50% (Atkinson). You can include this stuff below, but I would try to summarize it better and make it smaller. It is good information, and it still relates to the topic of anatomy and some radiography. But, from the previous paragraph on, I would start into your main topic: 1.) Defining Schizophrenia. 2.) how does advanced imagery relate to the study of mental illness. 3.) How does advanced imagery relate to the study of Schizophrenia. Then conclude the paper with a summation of all three, and where you think (or researchers think) the next level of this study goes. The brain is one of the most complex organs in the body. According to Simon, schizophrenia is a “biological disease of the brain”. The areas of the brain that are affected by this disease include: the ventricles, the prefrontal cortex, auditory cortex, visual cortex, the thalamus, hypothalamus, and the limbic system, which includes the amygdala and the anterior cingulate, …show more content…
The limbic system, which involves the frontal lobe, deals with memory and emotion. Parts of the limbic system include the amygdala and the cingulate. The amygdala contains key brain nuclei for processing fear and stimulating the appropriate response to fear. The cingulate allows people to shift between thoughts and express emotions. And another affected part of the brain is the basal ganglia. The basal ganglia is involved in motor control which can help explain why damage to this area may affect a catatonic schizophrenic when they become hypnotized in an action. One study done revealed if two areas of the brain, the prefrontal cortex and the basal ganglia, have a great disconnection, the higher level of psychosis will be seen (Yoon). While for the auditory and visual cortexes of the brain may affect the paranoid schizophrenic when they have

Related Documents

  • Improved Essays

    The interesting thing is; cannabis alone will not trigger schizophrenia. Many factors that will include ones family history, other drugs, childhood trauma or even where someone lives are all factors that can be tied to the development of schizophrenia. The film suggests that the reason so many individuals who have schizophrenia have also consumed large amounts of cannabis because they wanted to block early symptoms of mental illness. Meaning that smoking offered them a good short-term effect which was that they would be more calm, however, that within the next one to two hours the effects would turn to the worst and they would become more paranoid then before. Hence why many of these people would smoke so much, they never wanted to stay calm without knowing that doing this would be worse in the long run.…

    • 539 Words
    • 3 Pages
    Improved Essays
  • Great Essays

    5). Amongst other factors, an individual’s dopamine levels are a big contributor to the reason a person continues to use and abuse drugs (Nutt, 2012, p. 139). Since dopamine levels stimulate the reward and pleasure areas of a person’s brain, when a drug is taken and their dopamine levels spike up, they will feel immense happiness and pleasure. However, what comes up must come down, and like all other things, their dopamine levels will go back down (Nutt, p. 139). During the “come down”, the individual will experience depression –like symptoms and the brain will start to recognize and associate happiness with the drug that they are taking.…

    • 1772 Words
    • 8 Pages
    Great Essays
  • Improved Essays

    Numerous studies conducted on the brains of deceased schizophrenia patients point out a high number of dopamine receptors (Seeman 2007). For that reason, researchers conclude that the previously mentioned result in hallucinations and paranoia found in patients with Schizophrenia. Moreover, the use of illegal substances, such as cocaine and amphetamines, amplify dopamine levels, enhancing the symptoms related to the disorder (Seeman 2007). This disease affects regions of the brain, specifically the thalamus and amygdala. The thalamus transmits the filtered sensory signals to the brain 's cortex, which handles alertness, consciousness, and sleep.…

    • 792 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    There are a wide range of explanations for schizophrenia (SZ), ranging from genetics to psychodynamic approaches. These theories can be grouped into two categories; biological and psychological. These two explanations have many differences such as their fundamental basis, treatments and methodology, but also have several similarities. This essay will outline, then compare and contrast various theories within the biological and psychological explanations. One aspect of the psychological explanations of SZ is the behaviourist approach.…

    • 1611 Words
    • 7 Pages
    Great Essays
  • Improved Essays

    Dopamine is the main reward pathway as well as being a hormone it’s the main factor that impacts an individuals feeling of pleasure. However, when taking a drug this can work in place of the chemical neurotransmitter, therefore interfering with the balance of this chemical to make it imbalanced and therefore disrupting behavior of the typical neural communication. An example of this is the use of conventional antipsychotic drugs in the treatment of schizophrenia, these bind to dopamine receptors but don’t actually stimulate them and consequently because of this these are known as antagonists, this therefore has the effect that it reduces stimulation of dopamine particularly in D2 receptors; doing this reduces the amount of dopamine transmitted to the postsynaptic neuron decreasing and by doing this it therefore stops the brain receiving this excess of dopamine delaying the effects which is thought to cause schizophrenia when there is an excess eliminating the symptoms (Wiley & Sons,…

    • 1449 Words
    • 6 Pages
    Improved Essays
  • Decent Essays

    The more dopamine, equals less prolactin and less dopamine, equals more prolactin. The two together contradict one another. This relationship between dopamine and prolactin is the negative feedback loop. There are two conditions someone could have if…

    • 216 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    Methamphetamine is highly addictive, which causes the brain to speedily build a tolerance to the drug, leading to the cycle of dependence and abuse, a chronic relapsing brain disease that drives compulsive drug consumption. This occurs in the “crash” stage, where the user experiences severe depression, irritability and fatigue and requires more of the drug to experience the high stage, which places further high demands on the dopamine…

    • 1046 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    This may lead to exaggerated messages and cause problems with communication within the brain. Drugs of abuse such as nicotine, cocaine, marijuana, and others affect the brain’s “reward” circuit. This particular circuit is located in the limbic system of the brain. Normally, when dopamine is released, the “reward” circuit creates feelings of pleasure. When drugs take control of this system, large amounts of dopamine are released; this causes the “high” or euphoria linked with drug use.…

    • 458 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    My best friends invite me over for pizza and a friendly game of cards. As I am enjoying my evening eating pizza, socializing, and playing cards, certain parts of my brain are involved which allow me to perform properly. The limbic system comprises of the thalamus, hypothalamus, hippocampus, amygdala, and the cingulate cortex. In general, the limbic system is involved in emotions, motivation, memory, and learning.…

    • 536 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Synaptic Pruning Effect

    • 742 Words
    • 3 Pages

    Prefrontal Cortex damage can cause disinhibition, such that the behavior of a subject is guided by previously acquired responses. These responses are usually inappropriate to the current situation. (Price). Pathological disturbances of mood may follow a bipolar course, in with normal moods alternate with both depression and mania. (Price).…

    • 742 Words
    • 3 Pages
    Improved Essays
  • Superior Essays

    Once a person consumes meth it produces an imposter dopamine between each one of those cells; therefore, causing an extremely good feeling of sensation throughout their body leaving them searching for that first high. In addition, after a period of time the brains receptors become blocked from the large amounts of dopamine produced by the meth. Throughout that time the brains reward system which is called the mesolimbic pathway is affected. Lee states, “this is one of the areas of the brain that is most powerfully associated with pleasure… also highly associated with addiction”…

    • 1524 Words
    • 7 Pages
    Superior Essays
  • Decent Essays

    Cocain Abuse Case Study

    • 505 Words
    • 3 Pages

    The other population of medium spiny nuerons interatcs with dopamine through a different receptor by the name of D2R. Whnever this recepotr was activated after the mice was injected with cocaine it caused an attentuation or reduction in euphoria. WHat's so interesting about thiis activty is that duing the expereince they found that D1R activation iinctease and D2r activation decreased immeediately after the mice were injected with cocaine, both in the mice that was exposed to the drug for the first tme and in the mice that was epxosed tot he drug on a daiily basis for two weeks. However, in both grops, the raiton of D1R activation and D2R activation, shiftend in favor of the reard and motviation promtoing effects of D1R. MEaning that, even though both groups of mice expereinced the counter effects of D1R when it was activated, whiich causes a reduction of euhporia and drug seeking tendancies, there was a higher level of activation within the D2R receptors. The researchers argue that this demonstrates why people continue to seek drugs, despite the fact that the effects they expereince tend gradually diminsehes after prolonged…

    • 505 Words
    • 3 Pages
    Decent Essays
  • Improved Essays

    In the 1800s the French offered illicit drugs which included hashish, which is a concentrated form of marijuana for individuals who experienced emotional and stressful situation. To alter their mood, to stimulate a happier state of being although being aware of the possible consequences. The psychoactive drugs were merely used as a relaxer for social and recreational purposes. Since the neural basis is a modern concept of the neuroscience to define and understand the biological processes of a human being’s normal pathological behavior, and how it worked in the body. The concern needs to be the long term detrimental factor of using hashish instead of focusing on the benefit it has to offer individual with mental disorders.…

    • 305 Words
    • 2 Pages
    Improved Essays
  • Great Essays

    Essay On The Limbic System

    • 1079 Words
    • 5 Pages

    In this paper, I decided to do research on the limbic system. The Limbic system is the area of the brain where emotional processing occurs. It was a large interest to me since I always found emotions to be absurd in some way. This research is important because it breaks down the complexity of how emotions work in the brain and why we have emotions. Also, I attempted to use examples to facilitate the information for somebody who was not to scientific to understand the paper.…

    • 1079 Words
    • 5 Pages
    Great Essays
  • Improved Essays

    Cocaine Addiction

    • 1419 Words
    • 6 Pages

    that although cocaine dependant individuals have decreased ability for stimulus-response learning, their ability to make basic associations remains intact (Vadhan, 2014). As previously mentioned, cocaine gives the user a feeling of euphoria through the increased release and decreased reuptake of the dopamine neurotransmitter within the synaptic gap, especially in the nucleus accumbens (Volkow, 1997). Over time, the repetitive influx of dopamine molecules can have detrimental effects on dependant individual, including depression (Hart, 2012). A study performed by Valklow and colleagues uses Positron Emission Tomography (PET) imaging to view the brain’s response to a dopamine influx in both participants that have been previously cocaine dependant…

    • 1419 Words
    • 6 Pages
    Improved Essays