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1599 Cards in this Set

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The Maximum Allowable Cost is usually (greater than or less than) the Usual and Customary (U&C) price.
less than
What are the 2 general types of products parenterals are packaged as?
LVP-large volume parenteral solutions and SVP-small volume parenteral solutions
What is meant by Maximum Allowable Cost or MAC?
the maximum price per tablet (or other dispensing unit) an insurer or PBM will pay for a given product
What are the 2 general types of products parenterals are packaged as?
LVP-large volume parenteral solutions and SVP-small volume parenteral solutions
What is meant by U&C or UCR?
the maximum amount of payment for a given prescription, determined by the insurer to be a usual and customary (and reasonable) price
What would be a visual sign of lack of stability in a parenteral solution?
precipitation or crystallization in the solution
What does the DAW code 0 indicate?
No DAW
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What does the DAW code 1 indicate?
DAW handwritten on the prescription by the prescriber
What are aseptic techniques?
techniques that maintain sterile conditions and prevent contamination
What does the DAW code 2 indicate?
Patient requested brand
What would be a visual sign of lack of stability in a parenteral solution?
precipitation or crystallization in the solution
What does the DAW code 3 indicate?
Pharmacist selected brand
What are pyrogens?
chemicals that are produced by microorganisms
What does the DAW code 4 indicate?
Generic not in stock
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What does the DAW code 5 indicate?
Brand name dispensed but priced as generic
Can pyrogens be removed by sterilizing or filtering the solution?
no
What does the DAW code 6 indicate?
N/A
What are aseptic techniques?
techniques that maintain sterile conditions and prevent contamination
What does the DAW code 7 indicate?
Substitution not allowed; brand mandated by law
What is meant by a pyretic reaction?
fever
What does the DAW code 8 indicate?
Generic not available
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What does it mean when "Refills Not Covered" is the reason for a rejected claim?
The patient has a mail order pharmacy for maintenance medications.
What is the osmolarity of blood?
about 300 mOsmol/L
What are pyrogens?
chemicals that are produced by microorganisms
What is meant by isotonic?
when a solution has an osmolarity equivalent to that of blood
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What is osmotic pressure?
the characteristic of a solution determined by the number of dissolved particles in it
Can pyrogens be removed by sterilizing or filtering the solution?
no
What is meant by hypertonic?
intravenous solutions that have greater osmolarity than blood
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
What is meant by hypotonic?
intravenous solutions that have lower osmolarity than blood
What is meant by a pyretic reaction?
fever
What can hypertonic and hypotonic solutions do?
may cause damage to red blood cells, pain, and tissue irritation
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
What constitutes as an LVP solution?
intravenous solutions packaged in containers holding 100 mL or more
What is the osmolarity of blood?
about 300 mOsmol/L
What are the 2 ports on LVP solutions called?
the administration port and the medication port
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
What identifies the administration port from the medication port?
the administration port has a plastic cover; the medication port is covered by a protective rubber tip
What is meant by isotonic?
when a solution has an osmolarity equivalent to that of blood
How are medications that cannot be placed in plastic administered and packaged?
glass IV bottles are used; they are packaged with a vacuum, sealed by a solid rubber closure, and the closure is held in place by an aluminum band
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What are the 4 most commonly used LVP solutions?
sodium chloride solution, dextrose solution, Ringer's solution, and Lactated Ringer's solution
What is osmotic pressure?
the characteristic of a solution determined by the number of dissolved particles in it
What is an ampule?
an elongated sealed glass container with a neck that must be snapped off
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What are 4 names of Ready-To-Mix systems?
Add-Vantage, Add-a-Vial, Mini-Bag Plus, CRIS Controlled Release Infusion System
What is meant by hypertonic?
intravenous solutions that have greater osmolarity than blood
What is meant by lyophilized?
freeze dried
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
What is the lumen of the needle?
the hollow bore of the needle
What is meant by hypotonic?
intravenous solutions that have lower osmolarity than blood
What are Slip-Tip, Luer-Lok, eccentric, and oral referring to?
different types of syringe tips
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
How does a depth filter work?
works by trapping particles as the solution moves through twisting channels
What can hypertonic and hypotonic solutions do?
may cause damage to red blood cells, pain, and tissue irritation
How does a membrane filter work?
consists of many small pores of a uniform size that retain particles larger than the pores
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
What are 3 types of filters?
membrane, depth, and final filters
What constitutes as an LVP solution?
intravenous solutions packaged in containers holding 100 mL or more
What is commonly used in a depth filter?
diatomaceous earth, procelain, and asbestos
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What is meant by laminar flow?
continuous movement at a uniform rate in one direction
What are the 2 ports on LVP solutions called?
the administration port and the medication port
What is a HEPA filter?
a high efficiency particulate air filter
What is the lowest grade of purity to be used in compounding?
USP, or NF
Are TPNs hypertonic or hypotonic?
hypertonic
What identifies the administration port from the medication port?
the administration port has a plastic cover; the medication port is covered by a protective rubber tip
What is the source of protein in a TPN solution?
an amino acid solution
What is the lowest grade of purity to be used in compounding?
USP, or NF
What is the source of carbohydrate calories in a TPN solution?
a dextrose solution
How are medications that cannot be placed in plastic administered and packaged?
glass IV bottles are used; they are packaged with a vacuum, sealed by a solid rubber closure, and the closure is held in place by an aluminum band
What is a TNA?
Total Nutrient Admixture solution; a TPN solution that contains intravenous fat emulsion
What is the lowest grade of purity to be used in compounding?
USP, or NF
What are the 2 typical solutions for surgical irrigation and what is their purpose?
Sodium Chloride or Sterile Water; used to bathe and moisten body tissues, moisten dressings, and wash instruments
What are the 4 most commonly used LVP solutions?
sodium chloride solution, dextrose solution, Ringer's solution, and Lactated Ringer's solution
What are the 2 most commonly used Urologic Irrigation Solutions and what is their purpose?
Glycerine Irrigation and 3% Sorbital Irrigation solutions; they maintain tissue integrity and remove blood to maintain a clear field of vision
Why does drug distribution, metabolism, and excretion differ in neonates and infants?
their organ systems are not fully developed, such as liver function and the blood-brain barrier
What type of solution is used during operations to maintain tissue integrity and remove blood?
urologic irrigation solutions
What is an ampule?
an elongated sealed glass container with a neck that must be snapped off
A mole is the number of grams numberically equal to the ____ weight of the drug.
molecular weight
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
What is molecular weight?
the sum of the atomic weights of all the atoms that make up the drug molecule.
What are 4 names of Ready-To-Mix systems?
Add-Vantage, Add-a-Vial, Mini-Bag Plus, CRIS Controlled Release Infusion System
What is the formula to find a drug's osmolarity?
osmole = (molecular weight)/(# of ions)
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
What type of filter is used to filter solutions as the solution is expelled from the syringe?
membrane filters
What is meant by lyophilized?
freeze dried
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
What is the lumen of the needle?
the hollow bore of the needle
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
What are Slip-Tip, Luer-Lok, eccentric, and oral referring to?
different types of syringe tips
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
How does a depth filter work?
works by trapping particles as the solution moves through twisting channels
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
How does a membrane filter work?
consists of many small pores of a uniform size that retain particles larger than the pores
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
What are 3 types of filters?
membrane, depth, and final filters
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
What is commonly used in a depth filter?
diatomaceous earth, procelain, and asbestos
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
What is meant by laminar flow?
continuous movement at a uniform rate in one direction
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
What is a HEPA filter?
a high efficiency particulate air filter
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
Are TPNs hypertonic or hypotonic?
hypertonic
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
What is the source of protein in a TPN solution?
an amino acid solution
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
What is the source of carbohydrate calories in a TPN solution?
a dextrose solution
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
What is a TNA?
Total Nutrient Admixture solution; a TPN solution that contains intravenous fat emulsion
What kind of reference material does the DFC contain?
Contains information about prescription and OTC products. It divides the drugs into therapeutic groups. New or revised information is sent monthly.
What are the 2 typical solutions for surgical irrigation and what is their purpose?
Sodium Chloride or Sterile Water; used to bathe and moisten body tissues, moisten dressings, and wash instruments
What is the lowest grade of purity to be used in compounding?
USP, or NF
What are the 2 most commonly used Urologic Irrigation Solutions and what is their purpose?
Glycerine Irrigation and 3% Sorbital Irrigation solutions; they maintain tissue integrity and remove blood to maintain a clear field of vision
What is the NABP's definition of compounding?
the preparation, mixing, assembling, packaging, or labeling of a drug or device as the result of a practitioner's prescription drug order
What type of solution is used during operations to maintain tissue integrity and remove blood?
urologic irrigation solutions
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
A mole is the number of grams numberically equal to the ____ weight of the drug.
molecular weight
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
What is molecular weight?
the sum of the atomic weights of all the atoms that make up the drug molecule.
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
What is the formula to find a drug's osmolarity?
osmole = (molecular weight)/(# of ions)
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
What type of filter is used to filter solutions as the solution is expelled from the syringe?
membrane filters
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
What kind of reference material does the DFC contain?
Contains information about prescription and OTC products. It divides the drugs into therapeutic groups. New or revised information is sent monthly.
What is the lowest grade of purity to be used in compounding?
USP, or NF
What is the lowest grade of purity to be used in compounding?
USP, or NF
What is the lowest grade of purity to be used in compounding?
USP, or NF
What is Martindale, The Complete Drug Reference the best best source of information for?
Drugs in clinical use internationally. It contains drug monographs that provide information on the properties, actions and uses of drugs.
What is the NABP's definition of manufacturing?
the production, preparation, propagation, conversion or processing of a drug or device, either directly or indirectly, by extraction from substances of natural origin or independently by means of chemical or biological synthesis
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
What is the receptor and where is it located?
the cellular material directly involve in the action of the drug and is located on the surfaces of cell membranes and inside cells
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
How does the USP define the stability of compounded dosage forms?
the chemical and physical integrity of the dosage unit and the ability of the unit to maintain protection against microbiological contamination
What is the AHFS the accepted authority on?
For drug information questions. It is the leading source of drug information for determining reimbursement of prescriptions and as a resource for DURs.
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
What is Martindale, The Complete Drug Reference the best best source of information for?
Drugs in clinical use internationally. It contains drug monographs that provide information on the properties, actions and uses of drugs.
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
What is the Handbook on Injectable Drugs?
A collections of monographs on commercially available parenteral drugs that include concentration, stabality, dosage and compatibility information.
What is the lowest grade of purity to be used in compounding?
USP, or NF
What are some drugs that are eliminated faster in children than in adults?
clindamycin, valproic acid, ethosuximide, and theophylline
Out of 9 chemical grades, where does Technical, or commercial, grade rank?
lowest
What is a PDR?
Physicians' Desk Reference is an annual publication that provides prescription information on major pharmaceutical products.
What is the highest chemical grade and what is it used for?
Primary standard, used in standard solutions for analytical purposes
What is the AHFS the accepted authority on?
For drug information questions. It is the leading source of drug information for determining reimbursement of prescriptions and as a resource for DURs.
What are the 2 grades below USP/NF chemical grade?
Technical/commercial and CP (chemically pure)
What is the Merck Index?
An encyclopedic source of chemical substance data.
Where is the volume of aqueous liquid read on a graduated cylinder?
Bottom of the meniscus.
What does the American Drug Index provide?
The most exhaustive list of drugs and drug products.
What is the Handbook on Injectable Drugs?
A collections of monographs on commercially available parenteral drugs that include concentration, stabality, dosage and compatibility information.
What kind of information can be found in the Red Book?
Pharmacist's guide to accurate product information and prices on prescsricption drugs, OTC items and reimbursable medical supplies.
What is the meaning of additive effects?
when 2 drugs with similar pharmacological actions result in an effect equal to the sum of the individual effects
What is "Today's Technician" is an example of what kind of journal?
A professional practice journal.
What is a PDR?
Physicians' Desk Reference is an annual publication that provides prescription information on major pharmaceutical products.
When drug molecules bind with a receptor, they can cause a reaction that ____ or ____ cellular functions.
stimulates or inhibits
What is the Merck Index?
An encyclopedic source of chemical substance data.
What is synergism?
when 2 drugs with similar pharmacological actions produce greater effects than the sum of individual effects
What does the American Drug Index provide?
The most exhaustive list of drugs and drug products.
What is a
Prescription?
an order for a medication issued by a licensed medical practitioner, required if the medicine requires medical supervision because the drug is unsafe
What kind of information can be found in the Red Book?
Pharmacist's guide to accurate product information and prices on prescsricption drugs, OTC items and reimbursable medical supplies.
What is potentiation?
when one drug with no inherent activity of its own increases the activity of another drug that produces an effect
What is "Today's Technician" is an example of what kind of journal?
A professional practice journal.
What is a drug that activates receptors and produces a response that may either accelerate or slow normal cellular processes, depending on the type of receptor involved referred to as?
an agonist
What is displacement?
a drug bound to a plasma protein is removed when another drug of greater binding potential binds to the same protein
How often is a laminar air flow hood inspected?
Every 6 months ,, or twice a year.
What is inhibition?
when a drug blocks the activity of metabolic enzymes in the liver
What is a drug that binds to receptors but does not activate them, instead blocking the receptors' action by preventing other drugs or substances from interacting with them referred to as?
an antagonist
What is induction?
when a drug causes more metabolic enzymes to be produced, thus increasing the metabolic activity
The Pharmacist has asked you to obtain a MedWatch for so s/he can report what?
An Adverse event regarding a drug
What is the MEC?
minimum effective concentration, enough drug to produce an effect
After reconsitituting a powder, how long is it good for?
14 days.
What is the onset of action?
When the MEC is reached
Forms of a prescription
1. Written from an office
2. Phoned in by the office (only Rphs or interns can recieve) Exceptions of CII's.
3. The office can fax or transmit the prescription through the computer. (NO CII's)
ALSO: CII NO REFILLS. Controls 3-5 can only have a total of 6 fills, so a prescription must be written with 5 refills if it is a control, good for 6 months only. All other non-controls written PRN or with 12 refills are good only a year from the date the prescription is written.
What is the MTC?
minimum toxic concentration, blood concentration limit beyond which there are undesired or toxic effects
The middle four characters of an NDC number represent ?
Product, Strength, and dosage form.
What is the therapeutic window?
the range between the MEC and the MTC
When unit dosing a tablet, what is the necessary labeling for each unit dose label?
Generic and trade name of drug, dosage form, strength, pharmacy lot number, and expiration date.
What is the duration of action?
the time between the onset of action and when the MEC is reached again by the declining blood concentration level
The last two digits of the National Drug Code (NDC) indicate the ?
unit package size.
What are the ADME processes?
absorption, distribution, metabolism and excretion
Difference between a prescription order and a medication order.
Prescritpion order is GIVEN to the patient to have filled.
A medication order is written by a physician in an institution and kept in ONE sheet of paper in a file for all staff to use.
What is another term for the ADME processes?
disposition
The most inportant pieces of information to have on record in the event of a drug recall of medications are the ?
Lot number and expiration date.
What are metabolism and excretion combined called?
elimination
Medications for ophthalmic administration are usually available in what two ways?
Sterile isotonic drops or sterile ointment.
What is absorption?
the transfer of drug into the blood from an dministered drug product
The ICD-9 code required on insurance claim forms refers to the ?
diagnosis.
What can effect distribution?
if the drug cannot penetrate the tissue's membranes, if there is not enough blood flow to the tissue, and drug binding to proteins in the blood or in tissues
Refill requests procedure
Technicians can do refill requests, they must provide:
-pharmacy NAME and PHONE number
-patients NAME and DOB
-drug NAME,STRENGTH, DOSAGE(QUANTITY)
-directions to confirm NO CHANGE
-date of LAST REFILL

When refills are authorized document the number of refills, the date, and the name of the person authorizing.
When acids dissociate are they ionized or unionized?
ionized
What is ICD-9 code?
Intranational classfacation of diesases 9th division.
When bases are dissociated are they ionized or unionized?
unionized
When dispinsing Ventolin inhaler, how often must the patient Package insert (PP) be included with the drug product?
every time the prescription is dispensed
Why do unionized drugs penetrate biological membranes more easily than ionized drugs?
they are more lipid soluble, charges on biological membranes bind or repel ionized drugs, ionized drugs associate w/ water molecules, creating larger particles w/ reduced penetrating capability
Universal claim forms are used for:
Insurance billing.
What are biological membranes composed of?
lipids and proteins
Prescription LABEL requirements.
FDCA (REGULATES)
food, drug, and cosmetics act.

-name and adress of Pharmacy
-rx number
-dates
-name of prescriber
-name of patient
-directions (dosage)
- quantity, manufacturer, expiration, initials of dispensing pharmacists, pharmacy phone number, refills.
What is passive diffusion?
when drugs in the body's fluids move from an area of higher concentration to an area of lower concentration until equilibrium is reached
Online processing of a third-party claim to determine payment is called:
Adjudication
How do most orally administered drugs move in the body?
from the intestine to the blood and from the blood to the site of action
What Class drug recall is the most serious?
Class I
What are hydrophobic drugs?
drugs that are lipid soluble, therefore penetrate cell membranes easier
Referring patients to PharmD
If the question being asked does NOT have a FACTUAL answer ex. What is the generic name for xanax?.
Than the tech MUST refer the patient to the pharmD. Because:
1. Drug-Drug interactions
2. Drug-Disease state interactions
3. Drug-Food interactions

-aspirin and coumadin interact could cause internal bleeding.
-sudafed worsens high blood pressure and diabetes
-absorption of cipro, tertacycline decrease when taken with food. absorption of ketoconazole increase when taken with fatty foods. grapefruit interacts with calcium channel blockers and estrogens. warfarin interacts with food high in vitamin k
-
How do hydrophilic drugs penetrate membranes?
they move through water-filled passages called aqueous pores
Gentamicin can be given in which forms?
Intravenous and opthalmic
How do drugs that cannot pass through a membrane by passive diffusion enter a cell?
active transport
Dosage Forms- Tablets
-most popular
-mechanically compressed
-dissolution in stomach (slow)
What is the gastric emptying time?
the time the drug will stay in the stomach before it is emptied into the small intestine
IV's preprepared containing cytotoxic drugs are prepared in a(n) what?
Biological safety cabinent
What can affect gastric emptying time?
the amount and type of food in the stomach, the presence of other drugs, the person's body position, and their emotional condition
Chewable tablets
chewed and dissoved in the mouth prior to swallowing, can be swallowed whole.
What can bile salts from the intestinal tract do to the absorption of drugs?
they improve absorption of certain hydrophobic drugs
When an investigational drug expires, you should?
Record the quantity and lot number and return it to the manufacturer
What can enzymes do to the absorption of drugs?
they destroy certain drugs and decrease their absorption
Enteric-coated tablets
-special coating to prevent dissolution within the stomach
-meant to dissolve in the intestined only.
-NEVER TO CHEW OR BRAKE OR CRUSHED prior to ingesting
-not to be taken with anti-acids which cause diissolution in the stomach
Where do enzymes in the intestine come from?
some are added to the intestinal tract's contents from pancreatic secretions and some are present in the intestinal wall
Novaldex or ________ is an anti-estrogen type medication that is often used in the treatment of breast cancer.
Tamoxifin
What does protein binding cause?
the drug binds w/ proteins and the molecule is too big to pass through the membrane, so it is stored in the fat and muscle and gradually released as the blood concentration of the drug falls
Sub-lingual tablets
-placed under the toungue where active ingridient is rapidly absorbed into the BLOODSTREAM. fast absorption
-Avoids the first pass effect (where drug circulates through out the body before it is broken down by the liver
What are the 2 uses for terbutaline?
bronchodilation and to delay labor in pregnant women
Which drug agency is responsible for regulating medical devices?
FDA
What is an example of a highly selective tissue membrane?
the blood-brain barrier and finger and toe nails
Buccal tablets
-between cheek and gum
-drug is dissolved slowly over a period of time
What happens to a drug when it binds with a protein to form a complex?
the drug cannot pass through membranes and is inactive
Tylenol No. 3 is actaminophen 325 mg. and codeine _____mg.
30 mg.
What is a metabolite?
a drug after the body has transformed it
Film-coated tablets (biaxin and depakote)
-special coating that masks the objectionable odor or taste
-prevents detereoration due to light and air.
What is the primary site of drug metabolism in the body?
the liver
Penicillin VK 250 mg tabs po quid for 10 days; If the patient cannot swallow tablets and requests a liquid dosage form, what volume of 250mg/5ml supension should be dispenssed?
200ml
What transforms a drug into a metabolite?
enzymes
Sustained, time-released tablets
active ingridient is released at a CONSTANT RATE for a prolonged period of time
-long acting, delayed release, prolonged action
What does enzyme induction do to the metabolism of a drug?
it results in greater metabolism of a drug
When using a class A prescription balance, the least weighable quantity is what?
120 mg.
What is it called when drugs that have made their way to the gall bladder are emptied into the intestine after consumption of food and are reabsorbed back into the body?
enterohepatic cycling
Lozenges
-troches, or pastilles
-meant to dissolve slowly in the mouth to keep the drug in contact longer
What is first-pass metabolism?
the drug must go thru the liver before reaching systemic circulation, where enzymes can degrade or destroy a drug
You receive an order for 10mEq of magnesium sulfate to be added to a TPN. You have a 50-ml vial of 4 mEq/ml of magnesium sulfate in stock. How much do you need to inject into the TPN?
2.5 ml
If the kidney's process of filtration becomes impaired, how would this affect drug dosaging?
excretion would be reduced and drugs will accumulate in the blood; the dosage of drugs must be decreased or the dosing interval lengthened
Caqpsules
-drug enclosed within a gellatin shell
- after 10-30 mins with the stomach the gelatin dissolves and the drug is released
-eliminates bad taste and odor of drug
Which penetrates biological membranes more easily, ionized or unionized drugs?
unionized drugs
The form number for ordering Schedule II drugs is what?
DEA Form 222
Pellets
cylinder shaped tablets for implantation just under the skin for continous drug absorption.
The movement of the drug from the dosage formulation to the blood.
absorption
Effervescent tablets
active ingridient + sodium bicarbonate + citric acid, releasing carbon dioxide gas
-masks the taste of medication
Which drug can be used as a patch?
-Nuprcanial ointment
-clonidine
-amoxicillin
-vitamin C
Clondine
Absorption
drug gets absorbed into the BLOOD stream
A prescription order for neomycin 0.75 g PO bid x 30 days is submitted. In stock you have 500-mg tablets. How many tablets will the patient use per day?
3 tablets daily
Distribution
drug goes where it is NEEDED
How much cough syrup will a patient take in 24 hours if the dose is two teaspoonfuls every six hours?
40 mL
Metabolism
drug is broken down by the liver
Name a drug that requires a follow-up "cover" prescription when dispensed as a verbal order?
phenobarbital
Elimination
excretion from the body
The smallest gelatin capsule used for extemporaneous compounding is what size?
5.
Syrups (sugar)
high concentration of sugar hinders bacterial growth
Which of the following forms is needed for pharmacy to dispense controlled substances
Form 224
Solutions (Soln)
drug is UNIFORMLY DISPERSED through out the liquid, no shake well.
Coring can occur when what happens?
The needle is not correctly inserted into the vile.
Suspensions (Susp)
medication is insoluble in the liquid, SHAKE WELL
THe expiration date on a bottle of Cipro 500mg tablets states 4/04. WHen does this drug expire?
midnight 4/30/04
Elixer
sweetened water with alcohol, NOT FOR BABIES, ALCOHOL!
Furosemide or Lasix© is used as what?
A Diuretic
Tincture
HIGHEST CONCETRATION OF ALCOHOL
What is an antiandrogen? What is it used to treat?
Antiadrogen drugs inhibit the biological effects of androgenic hormones. Androgenic hormones are steroid hormone, such as testosterone or androsterone, that controls the development and maintenance of masculine characteristics. Thus, antiadrogen drug are used to treat illnesses stemming from the production of excess male hormones, such as prostate cancer.
NDC (national drug code): All drugs have an NDC number
3 sets of number
5#'s- manufacturer
4#'s- drug name and strength
2#'s- package size
ex. 00456-0122-30
The infusion rate of an IV is over 12 hours. The total exact volume is 800 ml. What would be the infusion rate in mls per minute?
1.11 ml/minute
Expiration Dates
A drug expires 1/09 means it expires january 31st of 2009 at midnight.

50% rule: in a repackaged vial half the way date from the exp date and todays date. If the exp date is years and years than one year from todays date.
What volume of a 2% erythromycin solution can be made from 15gm of erythromycin powder?
750ml
Pellets
cylinder shaped tablets for implantation just under the skin for continous drug absorption.
You have a 70% solution of dextrose. How many grams of dextrose is in 400 ml of this solution?
280 grams
Effervescent tablets
active ingridient + sodium bicarbonate + citric acid, releasing carbon dioxide gas
-masks the taste of medication
When unit dosing a tablet, what is the necessary labeling for each unit dose label?
Generic and trade name of drug, dosage form, strength, pharmacy lot number, and expiration date.
Absorption
drug gets absorbed into the BLOOD stream
The standard pediatric dose for cefazolin is 20 mg/kg/day. The order is wriiten for 150 mg TID. The infant weighs 8 lbs. This dose is...?
Too high.
Distribution
drug goes where it is NEEDED
The middle set of digits in a National Drug Code(NDC) number represents:
the product strength and dosage form
Metabolism
drug is broken down by the liver
Federal law requires pharmacies to have available for inspection Copy 3 of the DEA form 222 for a period of how many years?
2 Years
Elimination
excretion from the body
Services that summarize information from various primary sources for quick reference
abstracting services
Syrups (sugar)
high concentration of sugar hinders bacterial growth
An IV order calls for the addition of 45 mEq of CaCo3(calcium carbonate). You have a 25 ml vial of CaCo3 4.4mEq/ml. How many mls of this concentrate do you need to add to this IV?
10.2 ml.
Solutions (Soln)
drug is UNIFORMLY DISPERSED through out the liquid, no shake well.
Estraderm is available in which dosage form?
patch
Suspensions (Susp)
medication is insoluble in the liquid, SHAKE WELL
In this formula how much talc is needed to fill 120 grams?
nupercainal ointment - 4%
zinc oxide - 20%
talc - 2%
2400 mg
Elixer
sweetened water with alcohol, NOT FOR BABIES, ALCOHOL!
A glass compounding slab is used for?
A smooth surface to mix ointments and creams
Tincture
HIGHEST CONCETRATION OF ALCOHOL
A bottle of nitoglycerin has the label strength of 1/200 grams. What would this strength be in milligrams?
0.3 mg
NDC (national drug code): All drugs have an NDC number
3 sets of number
5#'s- manufacturer
4#'s- drug name and strength
2#'s- package size
ex. 00456-0122-30
Pseudoephedrine, a common ingredient in cold preparations, is contraindicated in which specific disease state?
hypertension
Expiration Dates
A drug expires 1/09 means it expires january 31st of 2009 at midnight.

50% rule: in a repackaged vial half the way date from the exp date and todays date. If the exp date is years and years than one year from todays date.
A pharmacy wants to mark-up a product by thirty percent. How much would an item cost with this mark-up, if it's original cost was $4.50?
$5.85
NSAIDs
Non steriod Anti-inflammatory drugs
Federal law requires an exact inventory must be kept for what?
morphine sulfate
Which drug agency is responsible to regulate medical devices?
FDA
The Material Safety Data Sheets (MSDS)
Provide information concerning hazardous substances.
An empty capsule number 5 will hold how many milligrams of powder?
100 mg
How much diluent do you need to add to 4 gm of powder to get a concentration of 500mg/ml?
8 ml
If Domeboro tablets are received from the wholesaler, where should they be stocked?
where the Bacitracin ointment is stored
What does DAW mean on a written prescription?
The brand name is to be dispensed as written.
The movement of drug molecules across membranes by active means, rather than passive diffusion.
active transport
Your pharmacy has recieved a prescription for Ointment XYZ and is not available commercially. The prescription is written for 30 g with 2 refills. According to the FDA guidelines, what is the largest amount your pharmacy can compound when originally filling the prescription in anticipation of refills?
90 g
Name a medication which must be crushed?
Ecotrin 325mg
The last set of digits of the NDC aare indicative of what?
package size
When adding weights to a Class A balance, you should use tweezers because?
The oils from your skin will dirty and alter the actual weights
The approximate size container for the dispensing of 180 ml of liquid medication would be?
6 ounces
The directions for use of a medication is "i si prn". The meaning of "si" is?
under the tongue
A patient asks whether he/she can take a certian medication with another one? As a pharmacy technician, what should you do?
Request the patient see the pharmacist for a consult.
What is an OTC drug that can be used to treat asthma?
Generic Name - Epinephrine

Trade Names - Adrenalin (inhaler), Bronkaid (IM), Medihaler (SC), Primatene (IV)
The doctor writes: ii gtts OU bid. What does this mean?
two drops in each eye twice a day.
What type of prescription balance must be used for compouding 120gms of a 1% topical antifungal cream?
class A prescription balance
Investigational drugs are regulated by who?
FDA
A compounding prescription says to prepare a medication and qs solution to 100ml. This means---
Add the appropriate solution to the medication to equal 100 ml
Which of the following books is used for FDA's list of approved drug products?
Orange Book
What type of measuring device should be used to measure 3ml of a liquid for compounding?
10ml cylindrical gradute
Propranolol is the same as what?
Inderal.
A sudden condition requiring immediate treatment.
acute condition
Thiazide diuretics are used to do what?
Manage the retention of water.
grinding of tablets into a fine powder in a porcelain lortar is an example of?
trituration
Which Act deals with the issue of safety caps on prescripton bottles?
The Poison Prevention Act
Which of the following drugs should not be stocked on an adult crash cart?
Nitroglycerin patches
An example of a major drug-drug interaction would be..?
warfarin-aspirin
Amoxicillin oral suspension is stable in a refrigerator for how many days after reconstitution?
14 days
The appearance of crystals in mannitol injection would indicate that the product was...?
Was exposed to cold.
Drug
is a substance intended for the use in the diagnosis, cure, treatment or prevention or disease in human beings or animals
How many 30 mg KMNO4 (Potassium Permanganate) tablets are needed to make the following soluton?
KMNO4 1:5000 600ml?
4 tablets
Normal Slaine (N.S.) contains:?
0.9 % NaCl
Dextrose 25% 1000ml is ordered. You have only dextrose 70% solution available. How much of the dextrose 70% solution and sterile water will you use to fill this order?
357 ml dextrose 70% and 643 ml sterile water.
A PCA is used to?
Administer controlled analgesics
The Occupational, Safety, Health Administration (OSHA) requires pharmacies to have Material Safety Data Sheets for what?
Each hazardous chemical used in the pharmacy.
Digoxin belongs to which drug classification?
cardiac glycoside
Of the following group names, which one would be used for a cough?
-antihelmintics
-antitussives
-antihistamines
-anticholinerginics
-antitussives
Subcutaneous Injections
Injected under the skin (insulin)
Tobrex© ophthalmic ung refers to what?
An Ointment used for the eye
A virus-caused systemic infection that causes inflammation of the liver
acute viral hepatitis
Suspending or thickening agents are added to suspensions to thicken the suspending medium and the sedimentation rate. Which of the following is not a suspending agent?
-carboxymethylcellulose
-tragacanth
-acacia
-bentonite
Acacia
Intramuscular injections
Drug is injected into muscle for slow absorption
Oral Polio Virus Vaccine (Poliovax©) should be stored in a temperature not to exceed 46 degrees Fahrenheit. What is this temperature in Centigrade?
**Use this formula: Centigrade = 5/9(Fahrenheit degrees - 32 degrees)*
8 degrees C
What is the brand name for benzodiazepine?
Klonopin
You recieve a prescription for amoxicillin 75 mg QID for ten days. How many mls of amoxicillin 250 mg/5ml do you need to fill this prescription to last the full ten days?
60 ml
Intraarterial injections
Drugs injected into artery
The doctor writes for aminophylline 125 mg po QID x 10 days. You only have the solution 250/5 ml. How much would be needed for one dose?
1/2 teaspoonful
Lipids should be stored where?
At room temperature
Of the following schedules, which one deals with drugs that have no medicinal use in the U.S and have a high abuse potential?
-Schedule I
-Schedule II
-Schedule III
-Schedule IV
Schedule I
Intratheccal Injections
Drug is injected into space surrounding spinal cord
You recieve a prescription for sertraline (Zoloft©) qd x 30 days. What is sertraline?
Antidepressent
Name a drug that is likely to cause a photosensitivity reaction?
tetracycline
All aseptic manipulations in the laminar flow hood should be performed at least how many inches from within the hood?
6 inches within the hood
Intracardiac injections
Drug injected into heart
Which auxillary label would be used for a prescription for tetracycline 250 mg capsules?
Avoid Dairy Products and Antacids.
What are shingles? Name the anti-viral drug that is used to treat shingles?
Shingles is a disease caused by the varicella-zoster virus, the same virus that causes chickenpox. After an attack of chickenpox, the virus lies dormant in the nerve tissue. As we get older, it is possible for the virus to reappear in the form of shingles.

There is no cure for shingles, but the severity and duration of an attack of shingles can be significantly reduced if patient is treated immediately with antiviral drugs, such as ACYCLOVIR.
You recieve an order for kaopecttate 30 ml bid prn. How many tablespoonsful is one dose equal to?
2 tablespoons
Intravenous Injections
Bolus- drug given all at once
Drip- given over long period of time
Which of the following is a Schedule II Controlled Substance?
-diazepam
-meperidine
-pentazocine
-propoxyphene
Meperidine
What drug in a dose of 20mg qd, is used to treat dyspepsia?
Pepcid
If the manufacturer' expiration date for a drug is 12/08, the drug is considered acceptable to dispense until which date?
-12/01/08
-12/31/08
-11/30/08
-1/01/08
12/31/08
enteral
medications enters digestive tract, then absorbed into blood
The Roman Numerals XLII is equivalant to what?
42
When stocking shelves with new stock, you should?
Remove all outdated stock first and rotate stock, placing the longer expiration dates to the back.
A small volume intravenous bag specifically used to deliver medication is called an what?
IVPB
Parenteral
bypasses digestion and enters the blood directly
How many days will the following prescription last?
Prozac© 10mg #120 Sig: 2 po BID
30 days
The directions for use for Timoptic is ii gtts os bid. What is the meaning of os?
left eye
The laminar flow hood should be left operating continuously. If it is turned off, it should not be used until it has been running for at least how long?
Thirty Minutes
NS
Normal Saline, 0.9% NaCl
Which auxillary label would you use for this particular sig: ii gtts AU bid?
For the ear
A drug that is added to a parenteral solution
additive
A dose is written for 5mg/kg every either hours for one day. The adult to take this medication weighs 145 lbs. How much drug will be needed to fill this order?
989 mg
D5W
5% Dextrose in H20
How much medication would be needed for the following order?

Prednisone 10mg, on qid x 4days, on tid x 2 days, one bid x 1 day then stop
24
What is the Latin abbreviaiton for "after meals"?
pc
Benzethidine is in DEA Schedule 1, meaning that benzethidine has/can what?
Has no currently accepted medical use in the United States.
Which of the following explanations best defines formulary?
A list of drugs that are approved by the P and T committee.
In which controlled substance schedule is Tylenol© No. 2 classified?
Schedule III
An order reads "Tylenol 325mg PR q4h prn." What dosage form should tbe dispensed?
suppositories
Assuming that one pint is equal to 473 ml, how many pints can be found in one liter?
2.1 pints
antibiotic
drug that destroys microorganisms
Licensing and general professional oversight of pharmacists and pharmacies are carried out by who?
State board of pharmacy
A pharmacy technician repacks bulk solid dosage forms into unit dosed packages. What expiration date will appear on the package?
50% of labeled expiration date to a maximum of 1 year
Most unit-dose systems provide each patient with a storage bin in which can be found a supply of drugs for how long?
twenty-four hours
Which drug is not available in the dosage form described?
Prednisone 1mg/ml suspension
The first line of defence against infection/contamination of an IV product is what?
handwashing
The abbreviation "PCN" means what?
penicillin
HIPAA requires that..?
privacy rules are observed for PHI
The increase in effect when two drugs with similar pharmacological actions are taken
additive effects
Which of the following medications must be administered in a glass IV container?
nitroglycerin
What drug is used as a "RESCUE" from toxicity of methotrexate?
leucovorin
Preservative-free drugs must be used when drugs will be injected by which route of administration?
intrathecal
A prescription calls for amoxicillin suspension to be compounded. What auxillary label(s) will you place on the container?
Keep refrigerated; shake well before using; expiration date.
The two parts of the syringe that should not be touched are what parts?
the tip and needle
A patient hands you an empty vial of Ritalin and asked for the Rx to be refilled. What should you do?
tell the patient that the medication is not refillable
The sale of what medication is restricted by the Combat Methamphetamine Epidimic Act (CMEA)?
Claritin-D 24©
In a hospital setting, how do physicians place their prescription orders?
Via medication orders.

In the hospital pharmacy the medication order is the equivalent to the prescription in the retail pharmacy. ALL prescriptions (OTC and Rx) require a medication order.
The first five digits of the National Drug Code (NDC) number identifies the...what?
Manufacturer
ROM
read-only memory
The Orange Book provides information about what?
Generic equivalents
What is the proper procedure for cleaning a laminar flow hood?
clean the hood from side to side starting from the back of the hood towards the front of the hood
From the following directions how many tablets should be despenced?

2 tabs po qig x 2 days, then 1 tab po tiq x 2 days, then ss po bid x 2 days then dc.
24
RAM
random-access memory. information is defined by user.
What should the last digit be of this DEA number?
AB431762_
Five
Of the medications listed below, which one is a CII drug?
Meperidine
Aminosyn is an amino acid often used in TPN orders to provide protein for cellular repair and growth. A physician writes an order for aminosyn 2.5% 500ml. You only have aminosym 8.5% 500ml. How are you going to prepare this order using a sterile evacuated container?
add 147 ml of aminosyn 8.5% and qs with sterile water to 500 ml
Accupril
Generic: quinapril
antihypertensive
you are to use 2.4 ml of diluent to reconstitute a vial of medication. What size of syringe should be used?
3 ml
Which procedure would you not do when opening an ampule?
after wiping with an alcohol pad, dry the neck with a paper towel
The use of isopropyl alcohol is important as a mean to preven contamination of an IV prodcut. What sould the minimum percent of isopropyl alcohol used be?
70%
Aciphex
Generic: rabeprazole
for acid reflux
Nitroglycerin is provided in a sublingual tablet. this means what?
Tablet should be dissolved under the toungue.
A drug added to a prescription to enhance the action of the primary drug ingredient
adjuvant
(aj-uh-vuhnt)
The percentage or fraction of the administered dose of a drug that actually reaches systemic circulation and the rate at which this occurs is the drugs...
bioavailability.
Actonel
Risedronate
for osteoporosis
The type of formulary that allows the pharmacy to obtain all medications that are prescribed is a(an) what?
Therapeutic equivalence
How far within a hood should the pharmacy technician work?
at least 6 inches within the hood
Zantac, Tagamet and Pepcid are H2 blockers which are now available over-the-counter (OTC). What are these drugs used for?
used to inhibit stomach acid secretion
Actos
pioglitazone
for Type II Diabetes
A "hospital borne" infection is also known as a _____________ infection.
nosocomial
A CII drug can be refilled ?
A new prescription is needed for each prescription refill
Of the following drug recalls, which one is the most important in that all parties involved in the dispensing of a prescription (doctor, pharmacy and patient) must be notified due to the drugs potential or serious harm?
-Drug Recall I
-Drug Recall II
-Drug Recall III
-Drug Recall IV
Drug Recall I
Adderall XR
amphetamine
weight loss, stimulant
The pharmacist should be alerted if a petient is allergia to codeine and prescribed what instead?
Robitussin AC.
What size filter is considered a sterilizing filter?
0.22 micron
A prescription for amoxicillin 250 mg #30 has a usual and customary price of $8.49. The acquisition cost of amoxicillin 250mg #30 is $2.02. What is the gross profit?
$6.47
Advair
salmeterol with fluticasone
asthma
A senior citizen is pay for a prescription for penicillin VK 250 mg #30. The usual and customary price is #8.49. However this patient qualifies for a 10% discount. How much does the patient pay?
$7.64
ASHP
America Society of Health-System Pharmacists
A medication use to reduce a fever is called an what?
Antipyretic
Aldactone
spironolactone
hypertension
A prescription is written for Septra Suspension 240 ml 1 teaspoonful h.s. + 1 refill. The insurance plan has a 34-day supply limitation. How many ml can be dispensed using the insurance plan guidelines?
170 ml
How often must a laminar flow hood be checked?
every 6 months
A prescription is written for Albuterol Inhaler: Dispense 2 inhalers of 17gm, 2 puffs q.i.d. What is the days supply if there are 200 metered doeses in each inhaler?
50
Allegra
fexofenadine
allergies
A prescription is written for humulin N U-100 insulin 10 ml, 40 units daily. What is the days supply?
25
When a drug is recalled and is considered a Class I, this means what?
This is the highest level of recall for products that could cause serious illness or may even be fatal.
A prescription is written for Tetracycline HCI suspension 125 mg/5 ml compounded from capsules and a mixture of Ora-Plus 50% and Ora-Sweet 50%. How many capsules of Tetracycline 250 mg are needed to prepare 50 ml of this suspension?
5
Allegra D
fexophenadine + pseudoepedrine
colds/allergies
Convert the Celsius temperature of 100 degrees into degrees Fahrenheit.
212
How long may a schedule II drug be refilled?
no refills
How many doeses are in a 100 ml bottle of penicillin VK 250 mg/5 ml if each dose is 1/2 teaspoonful?
40
Altace
ramipril
antihypertensive
More than 3/4 of sales from pharmaceutical manufacturers are directly to who?
Wholesalers
The resulting solution when a drug is added to a parenteral solution
admixture
Which of the following medications is associated with gradual discontinuation of therapy?
Medrol
Amaryl
glimepiride
Type II Diabetes
Alprozolam is a/an:
-narcotic
-barbiturate
-benzodiazepine
-stimulant
benzodiazepine
If a prescription states "refill prn," for how long may this Rx be refilled?
1 year
A prescription for duragesic pathes should be filed under which DEA schedule?
Schedule II
Ambien
zolpidem
sleep aid
Which of the following medications is an antidiarrheal?
-propranolol
-famotidine
-methylphenidate
-loperamide
lopermide
When repackaging medications into unit dose containers, which of the listed required information does not need to be recorded in a logboook?
The patient's name and medical record number.
If a medication is to be taken a.c., it should be taken when?
before meals.
Amoxil
amoxicillin
anti-infective
Name a coronary vasodilator..
nitroglycerin
Antivent
meclizine
anti-emetic
What are the two most common side effects for opioid cough syrup?
dizziness and constipation

opioid - def. a drug, hormone, or other chemical substance having sedative or narcotic effects similar to those containing opium or its derivatives
Ativan
lorazepam
sleep aid, anxiety
What ratio of 25% dextrose and 10% DEXTROSE SHOULD BE MIXED TO MAKE A 20% DEXTROSE SOLUTION?
2:1
Augmentin w/calvulanate
amoxicillin w/clavulanate
antiinfective
Within the policies and procedures manual, the requirement for pharmacists to counsel patients on medications they have not taken before is listed under which law?
OBRA 90
Apri
desogestrel w/ ethinyl estradiol
contraceptive
How many 100mg tablets will be needed to make 1/2 liter of a 1:250 solution?
20 tablets
Avandia
rosiglitazone maleate
type II diabetes
An unintended side effect of a medication that is negative or in some way injurious to a patient's health
adverse effect
Avapro
irbesartan
antihypertensive
Codeine, meperidine and oxycodone all belong to which controlled schedule?
Schedule II
Aviane
levonorgestrel w/ethinyl estradiol
contraceptive
The program under the FDA that allows health care professionals to report any adverse reactions is
MedWatch
Bactrim
trimeth w/ sulfameth
antibiotic
A physician prescribes Ceclor 375mg po bid. What is wrong with this prescription?
the Rx lacks a duration of therapy
Bactroban
mupirocin
antibiotic
Antiviral
drug that attacks a virus
Bisoprolol
bisoprolol/hctz
antihypertensive
How often must controlled sunstances be physically inventoried?
once every 2 years
Capoten
Captopril
antihypertensive
As new stock arrives at the pharmacy, the technician should check the following information on the stock against the invoice:
Name, strength, dosage form, quantity, and expiration date
Cardizem
diltiazem
angina, hypertension
Name two drug classes that have cross sensitivity...
penicillin and cephalosporin
Cardura
doxazosin
hypertension
Drugs that activate receptors to accelerate or slow normal cell function
agonist
(ag-uh-nist)
Cefzil
cefprozil
antibiotic
Which government agency is responsible for safety in the workplace?
OSHA
Celebrex
celecoxib
arthrites
Which of the following automated systems is used specifically in hospitals to stock PAR levels of medications on nursing floors?
Pyxis
Celexa
Citalopram
antidepressant
Which dosage form is formulated to dissolve in the intestine rather than the stomach?
enteric-coated
Cipro
Ciprofloxacin
antibiotic
Which government agency regulates pharmacy tech and pharmacist licensure?
The State Board of Pharmacy
Clarinex
desloratidine
antihistimine
Determine the flow rate of an IVPB containing 120ml of gentamicin, if the solution is to be infused over a 1 hour period and the administration set is calibrated to deliver 10 drops per ml.
20 gtts/min
Claritin
loratidine
antihistamine
A drug manufacturer is required by law to recall any product that has been found to violate any of the following guidelines except
The drugs sent to the pharmacy were damaged in transit
Cleocin
clindamycin
antibiotic
A piggyback had 50ml of antibiotic infusing at a rate of 30 gtts/min. How long will it take for this solution to be administered if the set is calibrated to deliver 15 gtts/ml?
25 minutes
Catapres
clonidine
antihypertensive
A drug with agonist activity at some receptors but antagonist activity at others
agonist-antagonist
Combivent
ipratropium w/albuterol
asthma
How many 10 mg minoxidil tablets would be needed to make 60 ml of a 2 % solution?
120 tablets
Concerta
methylphenidate
OCD/ADD
Where would be the "best" place to store phenol?
On the bottom shelf behind cabinet doors
Coreg
carvedilol
congestive heart failure
Which nongovernmental agency is responsible for the accreditation of institutional settings?
JCAHO
Coumedin
warfarin
anticoagulant
Legend Drugs
require a prescription and are not considered safe without medical supervision
Cozaar
losartan
antihypertensive
The process whereby a drug crosses a membrane into the blood stream is called:
absorption
Darvocet N
propoxyphene N w/APAP
analgesic
Grinding tablets into a fine powder in a porcelain mortar is an example of
Trituration
Deltasone
prednisone
antiinflammatory
What solution is recommended for cleaning a laminar flow hood?
isopropyl alcohol
Depakote
divalproex
seizures
The organs from the mouth to the anus. The GI tract is a portion of this system.
alimentary tract
Detrol LA
tolterodine
incontinence
IF a manufacturer's labeling results in a temporary adverse health consequence, what type of FDA recall would be instituted?
Class II
Diabeta
glyburide
type II diabetes
Which drug agency is responsible for regulating medical devices?
FDA
Diflucan
fluconazole
antifungal
IS the following an acceptable or unacceptable DEA #: AH3126426?
unacceptable
Digitek
digoxin
congestive heart failure
What color do Gram-negative bacteria stain? Gram-positive bacteria?
Pink, Purple
Dilantin
phenytoin
seizures
A compounded prescription requires using 12 capsules costing $30.00 per 50 capsules and 120gm of an ointment base costing $7.50 per pound. If a $5.00 dispensing fee is included, how much should the patient be charged?
$14.18
Diovan
valsartan
hypertension
Which of the following medications is available as an inhaler for asthma?
Albuterol
Effexor XR
venlafaxine
antidepressant
At which temperature should procaine penicillin G be stored?
2-8 degrees Centigrade
Elavil
amitriptyline
antidepressant
A portion of a mixture
aliquot
Endocet
oxycodone w/apap
narcotic analgesic
What is the definition of "controlled room temperature?
15-30 degrees Centigrade
Estrace
estradiol
hormone replacement
Transdermal nitroglycerin would be kept in which section of the pharmacy?
The topicals
Evista
raloxifine
osteoporosis
What characterisitic is not important when preparing an IV admixture?
palpability-taste
Flagyl
metronidazole
antibiotic
antimycobacterial
drugs that attacks the organisms that cause TB and leprosy
Flexeril
cyclobenzaprine
muscle relaxer
Which drug information source would the pharmacy tech. check for a possible drug interaction?
Facts and comparisions
Flomax
tamsulosin
upper respiratory
A pregnant patient arrives with a prescription for temazepam 15mg q hs. What do you do?
Alert the pharmacist because this is a pregnancy category X
Flonase
fluticasone
allergies
Insulin is to added to an IV admixture. What type of insulin may be used?
regular
Flovent
fluticasone proprionate
asthma
The small sacs of specialized tissue that transfer oxygen out of the inspired air into the blood and carbon dioxide out of the blood into the air for expiration
alveilar sacs (alveoli)
folic acid
vitamin therapy
The process whereby a drug is transformed by the liver is called:
metabolism
Fosamax
Alendronate
osteoporosis
A stat order is called in by the pharmacy by a nurse in the hospital unit. What do you do?
You should give the phone to the pharmacist
Glucotrol
glipizide
type II diabetes
What is "Syrup of Ipecac" indicated for?
to induce vomiting
Glucophage
metformin
type II diabetes
What is the unit dose system?
The features of unit-dose system are the following:

1) a copy of the original physician's order is received by the pharmacy and is used as the dispensing document.

2) medications, including liquid and injectible medications, are prepared in ready-to-use forms and are dispensied per individual patient.

3) Individual doses of medications are labeled.

4) the pharmacy receives more pateint information, including drug allergies, weight, and possibly a medication history.

5) no more than a 24 hour supply of medication is dispensed.

--The advantages of using this system:
1) reduction in medication errors
2) improved medication control
3) decreased overall cost of medication distribution
4) more precise medication billing
Glucovance
glyburide with metformin
type II diabetes
A patient enters the pharmacy complaining of persistent heartburn. The pharmacy technician should;
tell the patient to speak to the pharmacist
Humalog
insulin lispro
type I diabetes
What is the proper procedure for cleaning a laminar flow hood?
Clean the hood starting from the back side to side, top to bottom toward the front.
Hydrodiuril
hydrochlorothizide
hypertension
Which of the following duties may a pharmacy technician not do?
accept a verbal order from a physician
Hytrin
terozosin
antihypertensive
A part of the lungs where gases are exchanged between blood and the air.
alveoli
Hyzaar
losartan/hctz
antihypertensive
Who implements formulary review?
P+T Committee
Imitrex
sumatriptan
migraine
Which of the agencies listed below is responsible for accreditation of an institutional facility?
JCAHO
Imdur
isosorbide mononitrate
angina
Suprax suspension requires which auxiliary label?
Shake Well
Inderal
propanolol
hypertension, angina
What term is used for the science that deals with the origin, nature, chemistry, effects, and uses of drugs and their interaction with the systems of living animals
Pharmacology
Keflex
cephalexin
antibiotic
Cleocin suspension is available in a concentration of 75mg/5ml.How many ml are required for a 300mg dose?
20ml
Kenalog
triamcinolone
topical anti-inflammatory
The main purpose of OSHA is to?
Ensure the safety of the workplace
klonopin
clonazepam
seizures
Tagamet IV has been ordered to run at 2.5 drops/min. It contains 875mg of Tagamet in a total of 250ml. How many milligrams of Tagamet will the patient receive per hour of the set is calibrated to deliver 15 gtts/ml?
35mg/hr
Lanoxin
digoxin
congestive heart failure
Sealed glass containers with an elongated neck that must be snapped off.
ampules
(am-pyool)
Lasix
furosemide
diuretic
Another pharmacy calls for a copy of an Rx and the pharmacist is busy counselling a patient. The pahr. tech should:
tell them that the pharmacist is busy and to call back later
Levaquin
levofloxacin
antibiotic
The MSDS contains what type of information?
The ingredients and specifics of all types of products
Levothroid
levothyroxine
hyperthyroid
Digoxin is available in alconcentration of 0.1mg/ml. How many ml are required to administer a 75mcg dose?
0.75ml
Levoxyl
levothyroxine
hyperthyroid
What is a long term effect of alcoholism?
Alcohol, in the long term, induces brain atrophy and decreases intellectual function.
Lipitor
atorvastatin
lipid-lowering drug
Heparin is available in a vial labeled 20,000U/ml. How many ml are required for a 12,500U dose?
0.625ml
Lopid
gemfibrozil
lipid-lowering drug
A computer program used for dispensing medication in the pharmacy setting is referred to as?
Software
Lopressor
metoprolol
angina, hypertension
Mylanta and Donnatal are to be combined in a 2:1 ratio. How much of each is required to make a 90ml of the suspension?
60ml/30ml
Lotensin
benazepril
angina, hypertension
A potentially fatal hypersensitivity reaction producing severe respiratory distress and cardiovascular collapse (arrest).
anaphylactic shock
Lotrel
amolodipine w/benazepril
antihypertensive
The directions for use of a medication are "ii gtts au q4hx5d." The proper interpretation of "au" is:
in both ears
Macrobid
Nitrofurantoin
urinary antiseptic
Materials management refers to ?
Inventory control,
Drug storage &
The drug procurement process
Microgestin FE
norethindrone w/ethynl estradiol
contraceptive
What is the proper method of measuring a liquid in a graduated cylinder?
hold at eye level and read the bottom of the meniscus
Minocin
minocycline
antibiotic
antiprotozoal
drugs that destroy protozoa
Mircette
desogesterol w/ ethinyl estradiol
contraceptive
The purpose of OSHA is to:
assure a safe workplace
Motrin
ibuprofen
NSAID
If a pharmacy pricing formulary is the AWP plus 4.5 and the AWP is $90 for 100 tablets, what is the charge to the customer for a prescription of 30 tablets?
$31.50
Monopril
fosinopril
antihypertensive
According to federal law, controlled substances must be safeguarded by:
dispensing records, storage records and inventory records, NOT transport records
Mycostapin
nystatin
topical antifungal
Without water molecules
anhydrous
Naprosyn
naproxen
anti inflammatory
The process of producing a smooth dispersion of a drug with a spatula is called:
levigation
Nasacort AQ
triamcinolone acetonide
allergies
The cost of 100 tablets of a bottle of aspirin is $1.50. What would the dispensing charge be to yield a 50% gross profit?
$2.25
Nasonex
mometosone
allergies
Which of the following groups is usually not a member of the P+T Committee?
dental representative
Necon
ethinyl estradiol w/norethindrone
contraceptive
What are some Schedule 5 drugs?
Cough syrup with codeine,
Lomotil (diphenoxylate hydrochloride with atropine sulfate)
Neurontin
gabapentin
anti-seizure
The purpose of the P+T Committee is to:
establish and maintain drug formularysystem,recommend policies regarding investigational drugs, collect data from drug utilization review
Nexium
esomeprazole
acid reflux
What program is administered by individual states?
Medicaid
Nolvadex
tamoxifen
breast cancer
Name a three beta blocking agents.
Normodyne, Tenormin, Lopressor
Norvasc
amlodipine
antidepressant
Male sex hormones
androgens
Ortho Tri-Cyclen and Ortho Cyclen
norgestimate w/ethnyl estradiol
contraceptive
The AWP for a gallon (3785ml) of antihistamine/antitussive cough syrup is $18.75, with an additional 20% discount from the wholesaler. What is the cost of 1 pint of th emedication?
$1.87
Oxycontin
oxycodone\
analgesic
AWP can be found in which book?
Drug Topics Red Book
Paxil
paroxetine
antidepressant
The "C" designation for the controlled substances must appear on a controlled prescription:
in red in the lower right hand corner of the Rx
Pamelor
nortriptyline
antidepressant
OTC (Over The Counter)
does not require a prescription and are considered safe without medical supervision
Pen Vee K
penicillin VK
antibiotic
The device that links computers via communication lines is called the:
modem
Pepcid
famotidine
acid reducer
If a manufacturer's invoice totals $520.00 with the terms 2% net, what amount should be remitted if it is paid within 30 days?
$509.60
Percocet
oxycodone w/APAP
analgesic
A MSDS provided what type of product information?
information regarding product ingredients
Procardia
nifedipine
angina, hypertension
A deficiency of red blood cells in blood
anemia
Plavix
clopidogrel
antithrombotic
The directions a prescription for prednisone 5mg tablets reads: Sig:2tabs po bid for 3 days, 3 tabs po qd for 2 days, 2 tabs po qd for 2 days, 1 tab po qd for 1 day then 1/2 tab po qd for 1 day. How Many tablets should be dispensed?
24 tablets
Provera
medoxyprogesterone
progesterone
When choosing between state and federal requirements, which take precedence?
The most stringent
Prozac
fluoxetine
antidepressant
A vial of reconstituted Adriamycin breaks inside a vertical flow hood. What should the tech.do?
clean up the spill with a "spill kit"
Pravachol
pravastatin
lipid-lowering drug
What are some effects of antipsychotic medications?
Extrapyramidal symptoms, often abbreviated EPS, is a neurological side effect of antipsychotic medication.
Premarin and Preempro
conjugated estrogens
The Roamn numerals XLII is equivalent to :
42
Prevacid
lansoprazole
acid reflux
A person who is over 65 years of age, who is disabled, or who has kidney failure would be covered by what insurance?
Medicaid
Prilosec
omeprozole
acid reflux
The phar.tech. is asked to assist in the compounding of a lotion. In what drug information source would this information be looked up?
Remington's Pharmaceutical Sciences
Prinivil
lisinopril
antihypertensive
Drugs that bind with receptors but do not activate them. They block receptor action by preventing other drugs or substances from activating them.
antagonist
Phenergan
promethazine
antihistimine, anti emetic
If a pahr. tech. discovers a medication has expired, he/she should:
follow the manufacturers return policy
Proventil, Ventolin
albuterol, asthma
Online processing of a third-party claim to determine payment is called?
Adjudication
Protonix
pantoprazole
acid reflux
What protective apparel must be worn when reconstituting a chemotherapeutic agent?
2 pair of gloves, a gown and mask
Reglan
metoclomapride
antihelminthic
drug that destroys worms
Remeron
mirtazapine
1+1/2 tablespoonsful is equivalent to how many ml?
22.5ml
Restoril
tamazepam
sleep aid
A substance which harms or kills microorganisns like bacteria and fungi.
antibiotic
Rhinocort
budesonide
antiinflammatory
How many ounces are contained in one pint?
16
Risperdal
risperodone
antipsychotic
The recommended storage temperature for unopened Xalantin is
2 degrees to 8 degrees Celsius (36 to 46 degrees Farhenheit
Serevent
salmeterol
asthma
Heparin belongs to which pharmacological category?
anticoagulant
Seroquel
quetiapine
antipsychotic
What is MAOI? What should patients taking MAOI avoid?
MAOI is an acronym for Monoamine Oxidase Inhibitor.

Monoamine oxidase inhibitors are a class of antidepressants used for the treatment of depression. Those on MAOI should avoid any fermented foods (wine, cheese, yogurt, etc). Also, do not mix with SSRI class of drugs (ex - prozac).
Sinemet
carbidopa w/levidopa
Parkinson's disease
When a drug is filtered by the kidney int othe bladder, this process is called:
elimination
Singulair
montelukast
asthma
What are the intravenous medications, which can be mixed with NS?
Cefazolin, Ampicillin, and Primaxin
Skelaxin
metaxolone
muscle relaxant
The computer program used for dispensing medication in the pharmacy setting is referred to as:
software
Somal
carisoprodol
muscle relaxant
A common home infusion service used for treating AIDS-related and other infections
antibiotic therapy
Synthroid
levothyroxine
hyperthyroidism
Goals, Policies, Procedures, and Mission Statements are all examples of:
strategic planning
Tenormin
atenolol
antiinflammatory
Of the needles listed which is in order from the smallest to the largest that are used in pharmacy?
27 gauge; 19 gauge; 18 gauge; 16 gauge
Tesyrel
trazodone
antidepressant
THe drug Pronestyl is ...
an antiarrhythmic
145. ἵστημι
145. ἵστημι
I place, set, stand, stop
PTEC
Pharmacy Technician Educator's Council
Tiazac
diltiazem
angina, hypertension
The dispensing label on an outpatient pharmacy prescription requires:
legal name of pharmacy and address
Timoptic
timolol maleate
glaucoma
Cyanocobalamin is what type of vitamin?
Vitamin B12
Topamax
topiramate
anti-seizure
A TPN order is to contain 2mg/l of folic acid. If the stock vial of Folic acid contains 5mg/ml, what volume would be required to prepare 3000ml of TNP
1.2 ml
Toprol XL
metoprolol
angina, hypertension
Compunding in advance of expected need
anticipatory compunding
Tricor
fenofibrate
lipid-lowering drug
Efudex cream
should be applied with gloves or a nonmetalic object
Trivora 28
levonorgestrel w/ethnyl estradiol
contraceptive
A person weighing 67 kg is how many pounds?
147.4 lbs.
Ultracet
tramadol w/acetaminophen
analgesic
Therapeutic equivalency indicates that the two drugs...
have the same quantity of active ingredient
Ultram
tramadol
narcotic analgesic
To what antimicrobial drug is there a high rate of resistance to by the bacteria "Staphylococcus"
Penicilin
Valium
diazepam
seizures, anxiety
Material management refers to
the drug procurement process, inventory control, and drug storage
Valtrex
valacyclovir
antiviral
A prescription for a buccal tablet would be labeled ____
Place against the inside of the cheek
Vasotec
enalapril
antihypertensive
The red "C" in the lower right corner of a prescription designates that the drug is:
Schedule II,III,IV, or V controlled substances
Viagra
sildenafil citrate
erectile dysfunction
A drug that antagonizes the toxic effect of another drug.
antidote
Vibramycin
doxycycline
antibiotic
Carbamazepine is an ...
anticonvulsant
Vicodin, Lortab
hydrocodone w/apap analgesic
An order of insulin is added to a TPN bag. The directions are to add a 100 units of insulin NPH. You draw up 10 ml of insulin, to push it into the bag. Is there anything wrong with this scenario?
You have added 10 times too much insulin.
Vioxx
rofecoxib
arthritis
The appearance of crystals in mannitol injection indicates:
that the solution is cold and the crystals may be redissolved
Voltaren
diclofenac
pain
bactericidal
Bacterial killing
Wellbutrin SR
buproprion HCL
antidepressant
The phar. tech is asked to divide 5 liters of Nilstat suspension into an equal number of 10ml and 15 ml unit dose dispensing cups. How many 10 ml dispensing cups can be made from this quantity of suspension?
200
Xalatan
latanprost
glaucoma
What solution should not be stored at 10 degrees celsius?
Mannitol solution
Xanax
alprazolam
anxiety
The initial dose of aminophylline for a non-smoking adult is 0.7mg/kg/hr for 12 hours. How many ml of an IV solution containing 400mg per 100ml would be required for a 154lbs male over this 12 hour period?
147ml
Zantac
ranitidine
acid reducer
Drugs that lower cholesterol and triglyceride levels
antihyperlipidemics
Zestoretic
lisinopril/hctz
hypertension
How many milliliters are contained in 1 1/2 tbsp. of liquid?
22.5 ml
Zestril
lisinopril
hypertension
What is the form DEA-41 used for?
Once controlled drugs are destroyed, the DEA requires the submission of this form.
Zithromax
azithromycin
antibiotic
Nocosomial infections are found to originate in _____.
In hospitals
Zocor
simvastatin
lipid lowering drug
A substance that acts against a toxin in the body; also, a vaccine containing antitoxins, used to fight disease.
antitoxin
Zoloft
sertraline
depression
Which of the drugs listed is a schedule IV drug?
Ativan
Zovirax
acyclovir
herpes/viral infection
Prescription
is an order for a medication or medical device, issued by a licensed prescriber
Zyloprim
allopurinol
gout
If a dose of medication is to be given at 0600, 1400, and 2200, the doses are given at what times?
6 AM, 2 PM, and 10 PM
Zyprexa
olanzapine
antipsychotic
The term half life refers to ______.
The amount of time it takes a chemical to be decreased by half of its strength.
Zyrtec
cetirizine
antihistamine
A drug that acts against a cough.
antitussive
a.s
left ear
The term prophylaxis means____.
Preventative treatment
a.u
each ear
Why is it important to track the dispensing of drugs and medications?
So that we can ensure proper use of medication.
o.d
right eye
Of the diagnostic devices listed below, which one is used for urinalysis?
Diastix
o.s
left eye
Water based.
aqueous
o.u
both eyes
Of the following drug combinations, which would be a drug-drug interaction?
Coumadin and aspirin
Finding milliequivalence
Add molecular weights. Divide by charge for g needed to make 1 Eq
bacteriostatic
Bacteria inhibiting
If nitroglycerin sl 1/200 grains was ordered, what strength would you take from the shelf to fill this order?
0.3 mg (Chapter 8)
Which of the following drugs causes photosensitivity?

ibuprofen
carbamazepine
tetracycline
both carbamazepine and tetracycline
The knob on a balance that prevents any movement of the balance pans.
arrest knob
Which of the following must be on an order for lasix tablets when it is presented to the pharmacy?

DOB
Patient Address
Drug Strength
Allergies
Drug strength
Extemporaneous compounding is when _____.
When a mortar and pestle is used to mix medication.
What are some duties of a long-term care pharmacist?
Distribution and consultation
Which of the following drugs does not require special handling and/or protective clothing?

Medrol injection
Adriamycin injection
mannitol injection
vincristine injection
mannitol injection
Which drug listed below is not an SSRI?
Elavil
Methods that maintain the sterile condition of products
aseptic techniques
Which drug listed is an antiviral?
Zovirax
Treatment for Malaria
quinine, made from the bark of the Cinchona tree
(also called "Jesuit's powder")
Which of the following is not available by injection?

Zantac
Micronase
Medrol
Lasix
Micronase
Which of the drugs listed is an SSRI?
Celexa
Which of the following might be contraindicated in a person with diabetes?

Procardia
Indocin
Isuprel
Micronase
Isuprel
A system in which medications are dispensed from an automated unit at the point of use upon confirmation of an order communicated by computer from a central system.
automated dispensing system
The main indication for the drug triamterene/HCTZ is ______.
Diuretic
An example of a drug-drug interaction might be

Procardia and verapamil
Coumadin and Tegretol
Naprosyn and Ceclor
acetaminophen and Tylenol # 3
Coumadin and Tegretol
What do the following abbreviations translate into?
1) buccal
2) SL
3) IV
4) PV
5) PR
6) SC/SQ
7) ID
1) Buccal - Between the cheeck and gum
2) SL - sublingual
3) IV - intravenous
4) PV - per vagina
5) PR - per rectum
6) SC/SQ - subcutaneous
7) ID - intradermal
2 drugs that synergize to produce an abnormally high level of toxicity are
streptomycin and furosemide
The main indication for the drug phenytoin is ______.
Anticonvulscant
Automated machines that fill and label pull bottles with correct quantities of ordered drugs
automated filling machines
The abbreviation ac means
Before meals
Which of the following is available as an inhaler for use by asthmatics

Calan
Lopid
Dyazide
Vanceril
Vanceril
virustatic
drug that inhibits the growth of viruses
A patient is taking aspirin. He is prescribed the following drugs. Which drugs would require that he change his pain reliever to acetaminophen?

Coumadin
Nicar
Ticlid
Both Coumadin and Ticlid
The abbreviation Rx means
Prescription
Which are delayed release?

Cytotec
Prilosec
Prevacid
Prilosec and Prevacid
Labels regarding specific warnings, foods, or medications to avoid, potential side effects, and so on.
auxiliary labels
Which of the following may cause smooth muscle contraction and possibly premature labor?
Carafate
Misoprostol
Nexium
Citrucel
Misoprostol
Which of the following drugs is an H2 antagonist?
Tagamet
A patient taking cyanocobalamin is taking
Vitamin B12
Who is responsible for restocking drugs?
The pharmacist and the pharmacy technician.
The drug Betagan would be used _____.
In the eye
Kills bacteria
bactericidal
The drug metronidazole comes in which dosage forms?
Tablets, capsules, Injectable, lotion, cream, and gel.
Dispensing directions
name, strength, dosage form, quantity and directions for use
The trade name for fluvastatin is _____.
Lescol
Retards bacteria growth
bacteriostatic
The trade name for glyburide is ______.
Micronase
What does the term "mic" stand for?
mic = minimum inhibition concentration;

When administering antimicrobial drugs, follow the "mic" standard so that the dosage is not too high or too low. If it is too low, the bacteria can grow resistant to the treatment. If it is too high, it can lead to an excess amount of unnecessary drugs in the system.
Which of the books listed is related most closely to the information contained in patient package inserts?
PDR
An angled surface at the tip of a needle
bevel
If a patient is allergic to penicillin and comes in with a prescription for Keflex, what should you know?
The patient might have sensitivity to this medication as well. Notify the registered pharmacist.
antineoplastic
Drug that inhibits new growth of cancer cells
KCI is an abbreviation for:_____.
Potassium chloride
a date assigned to a compounded prescription telling the patient when the formulation should no longer be taken
beyond-use date
You receive a prescription for a 5-year old patient for Cipro 500-mg tablets with instructions take 1 tab bid x 10 days. You would bring this to the attention of the pharmacist because ______.
The strength of the drug written is very high for a child. Notify the registered pharmacist.
What are the combination of drugs used to treat TB?
Isonazid, rifampin, and pyrazinamide.
The amount of hydrocortisone powder needed to prepare 8 oz of 2% hydrocortisone cream is _______.
4.8 g
The relative amount of an administered dose that reaches the general circulation and the rate at which this occurs
bioavailability
The medication that needs to be protected from light in a special container is _____.
Nitroglycerin
PTCE, PTCB, CPhT
Pharmacy Technician Certification
If the infusion rate of an IV is 1000 ml over 10 hours and the drop factor is 15 gtt/ml, what is the drops per minute?
25 gtt/min
Not irritating-, infection-, or abscess-causing to body tissue.
bicompatibility
How many drams are in 16 oz of solution?
120 drams
What are diuretic drugs? Why are they administered?
Diuretic drugs are substances or drugs that tend to increase the discharge of urine. In essence, they are "water pills" and they are used to treat hypertension by reducing the amount of water in the body and, thus, relieving the heart from pumping so much liquid.
How many grams of drug are in 500ml of solution if it is a 40% solution?
200g (Chapter 4)
The comparison of bioavailability between two dosage forms.
bioequivalence
How many milliliters of 35% acetic acid must be mixed with 15% acetic acid to give 1000ml of 10% acetic acid?
166.7 ml 35%; 833.3 ml of 15% (Chapter 4)
Inventory
Pharmacy products or merchandise that is available to meet future demands of customers
To prepare 500 ml of a 5% dextrose solution, you must use your available stock of 2% and 10% dextrose. How much of each will you need to prepare the order?
312.5 ml of 2%; 187.5 ml of 10% (Chapter 4)
The study of the factors associated with drug products and physiological proceses, and the resulting systemic concentrations of the drugs
biopharmaceutics
You receive an order for 1500 ml of 5% dextrose over 12 hours. The drop factor is 15 gtt/ml. What will the drops be per minute on this order?
31.2 gtt/min
What are antimetabolite drugs?
A group of anti-cancer drugs which prevent cells growing and dividing by blocking the chemical reactions required in the dividing by blocking the chemical reactions required in the cell to produce DNA.

Drugs of this type include 6 mercaptopurine, azathioprine, thioguanine, methotrexate.
An oral suspension comes in 100mg/5 ml. The doctor orders 0.25g PO tid. How many milliliters will this patient receive daily?
12.5 ml
Another term for an antagonist drug, because antagonists block the action of neurotransmitters
blocker
A doctor orders gentamicin 3mg/kg/day for a 75-lb child. How many milligrams will the child receive per day? You have in stock gentamicin 80mg/ml
102.3 mg/day (Chapter 4)
Generic Name
a contraction of the chemical name, sometimes indicating the chemical class to which the drug belongs to and is properly referred to as its nonproprietary name
Using your penicillin injectable stock of 125,000 units/ml, how many milliliters will it take to prepare 1 million units?
8 ml
A measure used for dosage that is calculated from the height and weight of a person and measured in square meters
body surface area
You receive an order for Demerol 20 mg IM. Your supply is Demerol 50mg/ml. How much will you draw into a syringe?
0.4 ml
What are some seizure medications?
Trade Name - Dilantin
Generic Name - Phenytoin
Drug Class - Hydentoin
A doctor prescribes his patient Vasotec7.5 mg PO bid x 30 days. You have 5-mg tablets in stock. How many will it take to fill this script?
90 tablets
A medication that decongests the bronchial tubes
bronchodilators
There is an order for epinephrine 10 mg stat. How much will you draw into a syringe from a 10-ml vial of epinephrine 1:1000?
10 ml (Chapter 4)
Inventory Control
A procedure whereby products are purchased in sufficient quantity to meet the anticipated demands of purchasers while controlling inventory size to generate optimal profits
You need to prepare a dose of lidocaine 500 mg with your supply, which is a 10-ml vial of 2% lidocaine. How much should you draw up into a syringe?
2.5 ml (Chapter 4)
A narrowing of the bronchi, accompanied by wheezing and coughing, i.e., an "asthma attack"
bronchospasm
A prescription order for neomycin 0.75 g PO bid x 30 days is submitted. In stock you have 500-mg tablets. How many tablets will the patient use per day?
3 tablets daily
What are H1 and H2?
H1 = hystemins and they are normally associated with allergies.

H2 = associated with GI.
How many grams of 0.45% normal saline and 5% dextrose are in a 1-L bag of IV solution?
4.5g of the 0.45% NS; 50 g of 5% dextrose.
Inside the cheek
buccal
Which of the following drugs requires an auxillary label stating that "This drug may cause discoloration of the urine?
Pyridium
What is the study of the uses of drugs in teh treatment of disease?
Pharmacotherapeutics
Which of the following drugs is not a laxative?
Imodium
Ingredients in a formulation designed to control the pH
buffer system
The Roman numeral CL is equivalent to____.
150
What drugs are commonly ordered in mEq?
mEq = one-thousandth of an equivalent.

Drugs with Mg, Potassium and Sodium Bicarbonate are commonly ordered in mEq.
You have a vial of heparin 20,000 units/ml. How many millimeters are needed for a 12,500 unit dose?
0.625 ml (Chapter 4)
Drugs that lower blood pressure by relaxing blood vessels
calcium channel blockers
A prescription is ordered for clindamycin suspension. You have 75mg/5ml in stock. How many millimeters are needed for a 300-mg dose for 7 days?
140 ml
Turnover rate
the number of times a product is purchased sold and replaced during a specific accounting period
Syrup of ipecac is indicated for what type of result?
Emesis
To set, mark, or check the graduations of a measuring device
calibrate
When insulin is added to a TPN, which type is used?
Regular
What is guanethidine commonly used for?
Guanethidine is used to treat high blood pressure. It works by decreasing your heart rate and relaxing the blood vessels so that blood can flow more easily through the body. WARNING: Due to severe side effects, guanethidine is no longer available in the U.S.
The type of measuring device used to measure out 2.5 ml of solution would be _____.
A 10-ml oral dose syringe
The ability of a substance to cause cancer
carcinogencity
(car·ci·no·ge·nic·i·ty)
A prescription is given to you for a medication which has the following sig: Take 1 tab sl prn. This translates to _____.
Take one tablet sublingual as needed.
Chemical Name
describes the structure of the drug by standard chemical nomenclature
The four middle numbers of the NDC represent ______.
The product, strength, and dosage form.
A type of ion
cation
The drug Prilosec is classified as a _______.
Proton pump inhibitor
What is emulsion?
1. A mixture of two immiscible (unblendable) substances. One substance (the dispersed phase) is dispersed in the other (the continuous phase).

2. A suspension of small globules of one liquid in a second liquid with which the first will not mix.
Which auxillary label(s) would need to be attached to the drug Orap?
Do not take if you are breastfeeding.(and) Do not take with grapefruit juice.
A system in which all pharmacy activities in the hospital are conducted at one location, the inpatient pharmacy
centralized pharmacy system
Of the drugs below, which one is not indicated to lower cholesterol?
Zaroxolyn
drug theft
illegally obtaining any medication
Which of the following drugs needs to be prepared in a laminar horizontal flow hood?
Nebcin and Septra
A continuing condition that requires ongoing treatment for a prolonged period.
chronic condition
If you have a 70% dextrose solution, how many grams are in 50ml of solution?
35g (Chapter 4)
Identify the following abbreviations:
1) NPO
2) Stat
3) PRN
1) Nothing by mouth
2) Immediately
3) As needed
You receive an order for 10mEq of magnesium sulfate to be added to a TPN. You have a 50-ml vial of 4 mEq/ml of magnesium sulfate in stock. How much do you need to inject into the TPN?
2.5 ml (Chapter 4)
A chronic and potentially fatal liver disease causing loss of function and increased resistance to blood flow through the liver
cirrosis
(si-roh-sis)
What volume of a 2% erythromycin solution can be made from 15g of erythromycin powder?
750 ml (Chapter 4)
Food and Drug Act of 1906
adulterated or misbranded
A prescription is written for Penicillin Vee K susp 500-mg PO qid for 10 days. What volume of a 250mg/5ml suspension will need to be dispensed to fill the order for 10 days?
400 ml (Chapter 4)
Areas designed for the preparation of sterile products
clean rooms
Estraderm is available in which type of dosage form?
Topical patch
What are antiestrogen drugs and what are they used for?
Antiestrogen: A substance that can prevent the full expression of estrogen.

Antiestrogens act by exerting antagonistic effects on target tissues (androgens and progestogens act in this way) or by competing with estrogens for access to receptor sites located on the cell surface.

For example, the drug tamoxifen (brand name: Nolvadex) is an antiestrogen that is used in the treatment of breast cancer and to reduce the breast cancer incidence in high-risk women.
How many doses of Zinacef 500-mg can be prepared from 10 gm bulk vial?
200 doses
A limited list of approved medications
closed formulary
Gentamicin can be given in which forms?
Intravenous and opthalmic
drug diversion
health professionals stealing narcotics for personal/recreational use
Which of the drugs listed below is not a cephalosporin?
Clarithromycin
An agreement for cost-sharing between the insurer and the insured
co-insurance
A prescription for APAP #4 contains how much codeine?
60 mg
When did the Industrial Era occur? How did the Industrial Era affect the practice of pharmacy today?
Era of relevance is late 19th century, specifically 1867-1940. The impetus for industrialization becoming a factor in the practice of pharmacy in America was the occurrence of major wars: the Civil War, World War I, and World War II. These major conflicts led to the development of weapons capable of causing increasingly serious and more frequent injuries. This, in turn, led to a greater demand for medicines, which in turn demanded a major shift in the process of medicine production. The most important manufacturing advance in the industrialization of the practice of pharmacy was the development of new machines for rapid mass production of medicines.
A prescription with directions to instill iii gtts OS qod would require the label to read ______.
Instill three drops into the left eye every other day.
The portion of the price of medication that the patient is required to pay
co-pay
Which of the following agents are sympathomimetic decongestants?
Pseudophedrine
Label Requirements
referred to as “dispensing labels”
Trace elements are used in the following solutions _______.
TPNs
A locked cart of medications designed for emergency use only
code carts
A patient requests valid refills of a rabeprazole and albuterol inhaler. Which two medications should be filled?
Aciphex and Ventolin
What is form DEA-106 used for?
When a robbery and/or theft occurs at a pharmacy, the DEA requires pharmacies to submit a DEA-106 with a detail account of what was lost/stolen.
Which of the following DEA numbers is correct for Dr. Paul J. Hanson?
AH 1234575
Particles up to a hundred times smaller than those in suspensions that are, however, likewise suspended in a solution
colloids
When a prescription inhaler is dispensed, how often should a patient package insert be given to the patient?
The first time the prescription is filled.
chemotherapy
any type of drug therapy but has usually describes drugs that kill a causative organ usually without harming the patient.
Usually treats CANCER
Congestion is not a side effect of...
Captopril (ACE inhibitor)
Federal law that sets daily and monthly limits on OTC sale of pseudoephedrine and ephedrine
CMEA - Combat Methamphetamine Epidemic Act
Sexual Dysfunction is not a side effect of....
Nifedipine (vasodilator)
What are "orphan drugs"?
The granting of the orphan drug status is designed to encourage the development of drugs which are necessary but would be prohibitively expensive/un-profitable to develop under normal circumstances.

In the United States, an orphan drug is any drug developed under the Orphan Drug Act of 1983, a federal law concerning rare diseases ("orphan diseases"), defined as diseases affecting fewer than 200,000 people in the United States or low prevalence is taken as prevalence of less than 5 per 10,000 in the community . This has been adopted as a subclause of the Food and Drug Administration (FDA) regulations. Because medical research and development of drugs to treat such diseases is financially disadvantageous, companies that do so are rewarded with tax reductions and a monopoly on that drug for an extended time (twenty years). Under the act many drugs have been developed, including drugs to treat HIV/AIDS, cystic fibrosis, and snake venom.
Asthma is not a side effect of.....
Clonidine (sympathoplegic)
When molecules of different chemicals attach to each other, as in protein binding
complexation
Nausea is not a side effect of.....
Loop dieuretics
The first anesthetic
cocaine (1884) (active ingredient in coca leaves)
Increased appetite is not a side effect of the drug....
Clozapine
Doing what is required
compliance
Epinephrine does not treat....
Renal disease
What is the enzyme system in the liver that is associated with drug interaction?
Cytochrome P450.

Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in breaking down chemicals such as drugs and endogenous compounds.
Ephedrine does not treat .....
COPD
A record of what actually happened when the formulation was compounded
compounding record
Barbiturates does not treat...
Hypotension
Antineoplastic therapy
general term for anticancer therapy
Nifedipine does not treat....
Fluid retention
A method of making suppositories in which the ingredients are compressed in a mold
compression molding
Methotrexate does not treat...
Rheumatic fever
What is gonadotropin?
Gonadotropins are protein hormones secreted by gonadotrope cells of the pituitary gland of vertebrates. The two principle gonadotropins are luteinizing hormone (LH) and follicle stimulating hormone (FSH). The gonads -- testes and ovaries -- are the primary target organs for LH and FSH.

Gonadotropin cells are targeted for treatment of infertility.
Prednisone does not treat...
Testicular Cancer
The strength of a solution as measured by the weight-to-volume or volume-to-volume of the substance being measured
concentration
Dexamethasone does not treat....
Wilson's disease
Auxiliary Labels
small labels that provide additional information, warnings, or reminders, that are affixed to the prescription container
What is the primary site of activity for Warfarin
Liver
The requirement of health care providers to keep all patient information private among the patient, the patient's insurer, and the providers directly involved in the patient's care
confidentiality
Which drug is associated with the reaction of hepatitis?
Isoniazid
How many refills are allowed for controlled/uncontrolled drugs?
For control 2, none.

For control 3, 4 and 5 - 5 refills per 6 months
The eyelid lining
conjunctiva
Cytotoxic therapy
Used to kill or arrest the growth abnormal cancer cells
Develops and maintains an individual pharmautical plan for each long-term care patient
consultant pharmacist
What type of service is now more impacted for pharmacists?
Pharmaceutical care
What is associated w/extreme photosensitivity?
Tetracycline
Device or formulation designed to prevent pregnancy
contraceptive
Prednisone drug toxicity does not cause....
Hypotension
1914 Harrison Tax Act
due to cocaine - narcotic folks be licensed & taxed
What is considered a class IA Sodium Channel Blocker?
Aminodarone and Propafenone
The mark (CII_CV) which indicates the control category of a drug with a potential for abuse
controlled substance mark
Who is C.D. Helper?
He established the concept of pharmaceutical care in the late 1980s.
Potassium sparing diuretics have the primary effect on the .....
Distal Convoluted Tubule
The change of one unit of measure into another so that both amounts are equal
conversions
What is not directly related to a drug toxicity of Nitroglycerin?
Projectile vomiting
the mechanism of action for antiandrogens
Blocks the remaining male hormones after the removal of the prostate (orcheitomy) or treatment that have blocked testosterone
Block hormones that are produced by the adrenal gland
When a needle damages the rubber closure of a parenteral container causing fragments of the closure to fall into the container and contaminate its contents
coring
What is Enalopril?
Enalopril is the generic name for Vasetec. It is an ACE inhibitor used to treat HTN. It can be taken PO or administered IV.
A tray designed for counting pills
counting tray
Patient Medication Profile
a listing of all medications dispensed by the pharmacy to a particular patient
A collection of information structured so that specific information within it can easily be retrieved and used
database
Identify the following abbrevations:
1) OU
2) OS
3) AD
1) Both eyes
2) Left eye
3) right ear
Mechanism by which a prescriber may indicate that the brand product, not the equivalent generic, must be dispensed
DAW
Cytotoxic drugs can be what?
Can be either carcinogenic, teratogenic, or mutagenic
Required on all controlled drug prescriptions; identifies the prescriber
DEA number
What does "allergic rhinitis" mean?
Runny nose
A system in which pharmacy activities occur in multiple locations within a hospital
decentralized pharmacy system
Pharmacokinetics is teh branch of pharmacology that deals with the scientific study of the _________,_________,_________,and _________ of drugs over time.
Absorption, distribution, metabolism, and excretion
A set amount that must be paid by the patient for each benefit period before the insurer will cover additional expenses
deductible
Define antagonism (think pharmacy).
Antagonism is the case when two drugs act to decrease the effect of each other.
The change of a drug to a less effective or ineffective form
degradation
What is the mechanism of action for hormone therapy?
Adds, blocks, or removes hormones that stimulate the growth of cancer cell
The bottom of right number in a fraction which is divided into the numerator to give the fraction's value
denominator
True or False: When a pharmacist administers a drug without a prescription, it is considered a felony.
true
The area in the muscle where a formulation is injected during an intramuscular injection
depot
Physicians Order Sheets
sheet where physicians orders for hospital inpatients or nursing home residents are written on
A filter that can filter solutions being drawn into or expelled from a syringe, but not both ways at the same time
depth filter
What Schedule of drugs is considered to have no medicinial value?
Schedule 1
A dried animal thyroid
desiccated thyroid
investigational drugs
drugs that have been studied in clinical trials but have not been approved by the FDA for the general population
Movement of particles in a solution through permeable membranes
dialysis
What are benzodiazepines?
The benzodiazepines are a class of drugs that are often used for short-term relief of severe, disabling anxiety or insomnia.

They are not to be taken with alcohol and they should not be discontinued abruptly.
A solvent that dilutes a freeze-dried substance or dilutes a solution
diluent
1927 Food, Drug and Insecticide Addministration
became FDA in 1930
The breaking apart of a tablet into smaller pieces
disintegration
What is cephalosporin? How many generations do they come in? Which generation is most effective against gram-negative bacteria?
The cephalosporins are a class of β-lactam antibiotics.

Cephalosporins are grouped into "generations" by their antimicrobial properties.

Generation 4 are most effective against gram-negative bacteria.
A drug bound to a plasma protein is removed when another drug of greater binding potential binds to the same protein
displacement
principal investigator
a physician specializing in the disease being studied
A term sometimes used to refer to all of the ADME processes
disposition
Identify the following abbreviations:
1) MI
2) IM
3) aa
1) MI = Myocardial Infraction
2) IM = Intramuscular
3) aa = one of each
When smaller pieces of a disintegrated tablet dissolve in solution
dissolution
Repackaging Log
a record of all activities related to the repackaging process and must be maintained
Makes sure long-term care patients receive the correct medications order
distributive pharmacist
What are the 5 different sources of drugs?
1) plants
2) animals
3) minerals
4) synthetic
5) engineered
Drugs that increase the elimination of salts and water through urination
diuretics
protocol
a plan that describes how an experiment or study is going to be conducted
When elements of ingested nutrients interact with a drug and this affects the disposition of the drug
drug-diet interactions
What is the purpose of the Pharmacy and Therapeutic Committee?
In the hospital pharmacy, the P&T committee determines which medications will be purchased and maintained in stock.
A digital subscriber line that provides digital sata transmission over the wires of a local phone network
DSL - Digital Subscriber Line
Pain relieving ingredient in white willow tree bark
salicylic acid (nature's aspirin)
Co-pays that have two prices; one for generic and one of brand medications
dual co-pay
Which Schedule drug has the highest potential of abuse?
Schedule 1
Status of medications lke Plan B that are classified as both prescription and OTC drugs
dual marketing
what are the aspects to consider when developing a drug
stability, toxicity , scheduling, and records
A small elevator that carries objects (but not people) between floors of a building
dumbwaiter
What are nitrates used for? Give an example of a nitrate.
Nitrates are used to relax muscle tone. Nitroglycerin is a drug that relaxes the heart's muscle tone.
The time drug concentration is above the minimum effective concentration (MEC)
MEC - Minimum Effective of Concentration
Dosage Form
refers to the physical form in which the drug product is made available for administration to the patient
Swelling from abnormal retention of fluid
edema
Which type of tablet is most suitable for children?
chewable tablets
The process of metabolism and excretion
elimination
Restricted drug
Drugs that are rarely used, have limited therapeutic options, and small patient populations
To quickly obtain a medication not currently in stock in the pharmacy in situations where the drug is urgently needed
emergency drug procurement
What is Methotrexate? What is it used for?
Methotrexate is a folic acid antagonist that prevents cancer cell growth.

Methotrexate is classified as an antimetabolite drug, which means it is capable of blocking the metabolism of cells. As a result of this effect, it has been found helpful in treating certain diseases associated with abnormally rapid cell growth, such as cancer of the breast and psoriasis.
A stablizing agent in emulsions
emulsifier
1938 Food, Drug and Cosmetic (FDC) Act
untested sulfanilamide - drugs must be safe before marketing
Mixture of two liquids that do not dissolve into each other; one liquid is spread through the other by mixing and using an emulsifier for stablility
emulsions
Who is regarded as the father of medicine?
Hypocrates
Produced from within the body or within a cell
endogenous
Dose
the quantity of drug taken by a patient
A route of administration to any organ in the alimentary tract (ie., from the mouth to the anus)
enteral
What are Barbiturates? What are they used for?
Barbiturates are short acting drugs used as general anesthesia.

Officially, Barbiturates are a class of chemicals derived from barbituric acid or thiobarbituric acid. Many of these are medically important as sedatives and hypnotics (sedatives, barbiturate), as anaesthetics, or as anticonvulsants.
The transfer of drugs and their metabolites from the liver to the bile in the gall bladder and then into the intestine, and then back into circulation
enterohepatic cycling
Tablets
solid dosage forms prepared by mechanical compression in a tableting machine
A complex protein that catalyzes chemical reactions into other substances
enzyme
What is Isoniazid?
Isoniazid is a crystalline antibacterial compound, C6H7N3O, used in the treatment of tuberculosis.
The increase in enzyme activity that results in greater metabolism of drugs
enzyme induction
dosage regimen
the schedule of medication administration
The decrease in enzyme activity that results in reduced metabolism of drugs
enzyme inhibition
Identify the following root words:
1) cardi
2) nephro
3) hema
1) cardi = heart
2) nephro = kidney
3) hema = blood
A drug's molecular weight divided by its valence, a common measure of electrolyte concentration
equivalent weight
What is the transformation of the drug by physiological processes of the body into other forms, ussually less potent or toxic than the original form that can be eliminated?
Metabolism
Combining an organic acid with an alcohol to form an ester
esterification
What are gamma rays used for in pharmaceutics?
Gamma rays are the most tissue penetrating energy packets and they are often used for sterilization of medical equipment.
Medications with habit-forming ingredients that can be dispensed by a pharmacist without a prescription to persons at least 18 years of age
exempt narcotics
Cost
Total paid for an item or items recieved as noted on an invoice
The on-demand preparation of a drug product according to a physician's prescription, formula, or recipe
extemporaneous compounding
Who promotes the certification of pharmacy technicians?
The American Association of Pharmacy Technicians
A filter that filters solution immediately before it enters a patient's vein
final filter
Chewable Tablets
compressed tablets that are designed to be chewed or dissolved
Protective coverings for fingers
finger cots
What are the consequences of not treating HTN?
Possibly a stroke and/or E.O.D.

E.O.D. = End Organ Damage (such as the eyes, legs and kidneys)
The substantial degradation of a drug caused by enzyme metabolism in the liver before the drug reaches the sytematic circulation
first pass metabolism
Selling price
100% of the amount that you will receive for the sale of the item
An expansion or outward movement by muscles
flexor movement
What drug is used to treat fungus in the mouth?
Nystatin
Electrolytes used in the preparation of suspensions
flocculating agent
1950 Alberty Food Products v. U.S.
drug purpose on label
Stock (such as large volume parenteral) that does not require patient specific labeling
floor stock
Fill in:

Drugs with high _____ _____ have a greater room for error.
Therapeutic index
The rate (in ml/hr or ml/minute) at which solution is administered to the patient
flow rate
markup
the difference between the cost and the actual selling price
A list of drugs stocked at the hospital which have been selected based on therapeutic factors as well as costs
formulary
What is Vancomycin used to treat against?
bacteria
Formulas and procedures (ie., recipes) for waht should happen when a formulation is compoounded
formulation record
Enteric-Coated Tablets
compressed tablets coated with a special substance to prevent the dissolution within the stomach
A suppository preparation method in which the active ingredients are dispersed in a melted suppository base
fusion molding
What are antibiotics?
Antibiotics are drugs that inhibit DNA/RNA synthesis
The time a drug will stay in the stomach before it is emptied into the small intestine
gastric emptying time
Drugs covered by the control substance Act
Opium, opiates, hallucinogens, depressants, stimulants, & anabolic steriods
A measurement with needles: the higher the gauge, the smaller the lumen
gauge
What are some examples of antibiotics?
1) Bieomycin
2) Doxorubicin
3) Dactinomycin
4) Mitomycin
5) Plicamycin
6) Vinblasine
A technique for mixing two powders of unequal quantity
geometric dilution
acetylsalicylic acid
aspirin
The blood filtering process of the kidneys
glomerular filtration
What does TPN stand for?
Total Parental Nutrition
Sex gland stimulants
gonadotropins
intravenous admistures
solutions compounded with two or more ingredients
A method for identifying microorganisms based on staining characteristics
gram stain
What are some common side effects associated with "Warfarin"?
Warfarin thins the blood, possibly causing patients to bleed to death.
The standard form used by health care providers, such as physicians, to bill for services; it can also be used to bill for disease state management services
HCFA 1500 Form
Sublingual Tablets
tablets you keep placed under your tongue so it is promptly absorbed into the blood stream
A federal act created to protect the privacy of individuals, patient health records, and the sharing of protected health information
HIPAA - Health Insurance Portability and Accessibility Act of 1996
What type of Schedule drug is Morphine?
Morphine is a Schedule 2 drug.
Painful swollen veins in the anal/rectal area, generally caused by strained bowel movements from hard stools
hemmorrhoid
sterile
Free from microorganisms and not producing any microorganisms; containing no bacterial or viral contaminants
A high efficiency particulate air filter
HEPA filter
What does Hematuria mean?
Hematuria is the presence of blood in urine.
An injection device which uses heparin to keep blood from clotting in the device
heparin lock
1951 Durham-Humphrey Amendment
legend - Rx only
Liver disease
hepatic disease
What are some common side effects of Erythromycin?
Nausea and vomitting
A prefix meaning "of the liver"
hepato
Compounding
the act or process of combining two or more drugs products or chemicals into a single preparation
A network of providers for which costs are covered inside but not outside of the network
HMOs
What are the duties and responsibilities of a pharmacy technician working in a hospital setting (inpatient)?
1) Maintenance of medication records.
2) Preparing unit doses.
3) Compounding medications.
4) Packaging.
5) Administration of medication.
6) Preparing and delivering prescriptions to patients who are out of the hospital, such as those in nursing homes, hospice, and rehabilitation facilities.
7) Computer data input.
8) Inspecting nursing unit drug stocks.
9) Inventory maintenance.
10) Preparation of labels.
11) Maintaining privacy.
12) Communication skills.
13) Working safely.
Home nursing care business that provide a range of health care services, including infusion
home care agencies
Buccal Tablets
tablets you keep between your gum and cheek so dissolves slowly over a period of time
The state of equilibrium of the body
homeostasis
What is HiPAA and how does it affect the pharmacy practice?
The Health Insurance Portability and Accountability Act (HIPAA) was enacted by the U.S. Congress in 1996.

Title I of HIPAA protects health insurance coverage for workers and their families when they change or lose their jobs.

Title II of HIPAA, the Administrative Simplification provisions, requires the establishment of national standards for electronic health care transactions and national identifiers for providers, health insurance plans, and employers.

The AS provisions also address the security and privacy of health data. The standards are meant to improve the efficiency and effectiveness of the nation's health care system by encouraging the widespread use of electronic data interchange in the US health care system.
Chemicals produced by the body that regulate body functions and processes
hormones
cytotoxic agents/cytotoxins
an agent that has specific toxic action upon cells of susceptible organs. Used to treat cancer
The part of the needle that attaches to the syringe
hub
What does the site of action include?
Local use and Systemic use
Absorbs water
hydrates
patient profile
a record containing information pertaining to a specific patient including demographic information, medical history, medication use chronology, allergies and chronic illnesses
Capable of associating with or absorbing water
hydrophilic
Film-Coated Tablets
coated with a thin layer of water-soluble material that masks the objectionable odor or taste of certain medications
A stabilizing agent for water-based dispersion mediums
hydrophilic emulsifier
diagnosis
indentified disease or health condition determined by the prescriber through assessment of the patient's sign and symptoms
Water repelling; cannot associate with water
hydrophobic
1962 Kefauver-Harris Amendment
saftey & effectiveness
An abnormal sensitivity generally resulting in an allergic reaction
hypersensitivity
psychosocial factors
involving both psychological and social aspects; relating social conditions to mental health
A condition in which thyroid hormone secretions are above normal, often referred to as an overactive thyroid
hyperthyroidism
Sustained, Time-Released Tablets
this is a tablet that is released at a constant rate for a prolonged period of time (8-24 hours) and are referred to as “long acting”, “delayed-release”, “prolonged-action”
When a solution has a greater osmolarity than that of blood
hypertonic
Desired therapeutic outcome
Desired health result of drug therapy
An abnoral concentration of uric acid in the blood
hyperuricemia
pharmacology
the study of drugs-their properties, uses, applications, and effects
A condition in which thyroid hormone secretions are below normal, often referred to as an underactive thyroid
hypothyroidism
"a" (SIG abbreviation)
Before
When a solution has a lesser osmolarity than that of blood
hypotonic
Lozenges
dissolve slowly to keep the drug in contact with the mouth or throat for a prolonged period of time and are referred to as “troches or pastilles”
Low oxygen levels in the blood, which can be caused by asthma
hypoxemia
a.a or aa
Of each
An unexpected reaction the first time a drug is taken, generally due to genetic causes
idiosyncrasy
1966 Fair Packaging and Labeling Act
honestly & informative
Cannot be mixed
immiscible
ac
before meals
A drug causes more metabolic enzymes to be produced, thus increasing the metabolic activity
induction
Pellets
small cylindrically shaped tablets meant for implantation subcutaneously (just under the skip) for prolonged continuous drug absorption
The gradual intravenous injection of a volume of fluid into a patient
inhibition
ad
up to
The first physician known by name was
The Egyptian Imhotep, born in 3,000 B.C.
What does each term refer to?
Local- site specific application
Systemic-application of a drug by absorption
Hippocrates approach to medicine was based on
careful observation
a.d.
right ear
The ancient Greek goddess of Medicinal Herbs was
Panacea
Capsules
a drug that is enclosed within a soft or hard gelatin shell that dissolves and the drug is released
Derived from the bark of the Peruvian tree, quinine populary called "Jesuit's powder", used along with preventive measures, helps keep this disease under control.
Malaria
ad lib
at pleasure
Aspirin is made from salicylic acid from the back of the _______ tree
willow
1970 Poison Prevention Packaging Act
child-proof
________ was the first effective local anesthetic
Cocaine
a.m.
morning
Around 3,000 B.C. _________ established, by trial and error, about 365 herbs that could be used as health treatments
the Chinese Emperor Shen Nung
Effervescent Tablets
tablets containing sodium bicarbonate with either citric or tartaric acid
An authoritative listing of drugs and issues related to their use is a(an)
pharmacopeia
ante
before
_____ showed that heat can be used to kill microogranism associated with food spoilage
Louis Pasteur
pharmacognosy
the study of physical, chemical, biochemical and biological properties of drugs & search for new drugs from natural sources
_________ discovered penicillin could kill some bacteria
Alexander Fleming
aq.
aqueous (water)
______________are substances produced by the body to regulate body functions and processes
Hormones
Solutions
mixtures containing one more soluble ingredient (solute) dissolved usually in water (solvent), in which the molecules of solute are uniformly dispersed among those of the solvent
____________ identified the structure of DNA
James Watson and Francis Crick
a.s.
Left ear
The pharmaceutical manufacturing industry devotes about ________of its income to research and development
one-sixth, 1/6
1970 Controlled Substances Act (CSA)
schedules - DEA (division of Justice)
______ protect(s) against illegal copying of new discoveries
Patenting
a.u.
each ear
The FDA is required to
1. ensure that a drug is safe and effective for its intended use
2. to monitor a drug after it is marketed to ensure it works as intended
3. to monitor a drug for any adverse effects
Syrups
sweet, viscous, concentrated, aqueous solutions of sugar that is used as a vehicle for antibiotics, antihistamines, antitussives (cough preparations) and vitamins as well as for other drugs
The length of time from the beginning of development of a new drug to FDA approval is often more than ________ years
ten
a.u.
each ear
In most cases the individual who dispenses the prescribed medication to the patent is the
pharmacist
What are the locations on the surface or within the cell that contain specific protein molecules that bind to other specific molecules, producing some effect in teh cell called?
Receptor Sites
The Omnibus Budget Reconiliation Act (OBRA) requires that pharmacists provide
counseling services to Medicaid patients
b.i.d.
twice a day
To become a pharmacist in the United States
an individual must graduate from an accredited college of pharmacy, pass a state licensing exam, and perform an internship working under a licensed pharmacist
Elixirs
sweetened hydroalcoholis (water and alcohol) solutions and are probably the most widely used
Because of their pleasant taste, relative stability and ease of preparation
The area of greatest employment for pharmacists is
community pharmacies
c. or c
with
The pharmacy technician may find the greatest employment opportunities in
the community setting
1976 Medical Device Amendment
safety & effectiveness devices
In managed care, care is managed by a(an)
insurer
cap
Capsule
Lists of drugs approved for use by managed care organizations are called
formularies
Tinctures
alcoholic or hydro alcoholic solutions prepared from vegetable, animal or chemical materials
Information that is entered and stored into a computer, such as a patient's name, is called
data
cc.
Cubic centimeter (millimeter)
The study of drugs, their properties,uses, application, and effects
pharmacology
materia medica
generally pharmacolgy, but also refers to the drugs in use
Drugs derived from plants to treat illness and other physical conditions
herbal medicine
Cl
Chloride
The drug of the foxglove plant which has been widely used in treating heart disease
digitalis
Suspensions
preparations containing insoluble medical products dispersed in a liquid
The theory that microorganisms cause food spoilage
germ theory
comp.
compound
Extracted from the bark of a Peruvian tree, quinine is the first useful drug in the treatment of malaria
quinine
1983 Orphan Drug Act
promote - rare diseases
Made from killed polio virus, the _______ ______ can be injected or taken orally
polio vaccine
DAW
Dispense As Written
The hormone that lowers blood sugar in threatment of diabetes
insulin
Emulsions
preparations containing either water dispersed in oil (w/o) or oil dispersed in water (o/w) stabilized with the acid of an “emulsifying agent”
Drugs created by reformulatingsimplex chemicals nito more complex ones, creating a new chemical not found in nature
synthetic drugs
D.C., dc, or disc
discontinue
The gradual intravenous injection of a volume of fluid ino a patient
infusion
What is the desired action of a drug or the action for which the drug is prescribed called?
Therapeutic Effect
A court order prevennting a specific action, such as the distribution of a potentially dangerous drug
injunction
dil
Dilute
A drug that increases the force of cardiac contraction
inotrope
Microemulsion or Transparent Emulsion
the particle size of the inner phase is 0.05 microns or less
Pharmacy located in a hospital or inpatient facility which services only those patients in the hospital/facility and ancillary areas
inpatient pharmacy
div
Divide
Breathing in
inspiration
1984 Drug Price Competition and Patent Term Restoration Act (Hatch-Waxman)
extension of drug patent & generics
The body covering, i.e., skin, hair, and nails
integumentary system
Dtd
Give of such doses
Skills involving relationships between people
interpersonal skills
Ointments
semisolid preparations used for external application to skin or mucous membranes
An intrauterine contraceptive device that is placed in the uterus for a prolonged period of time
intrauterine device (IUD)
Dx
Diagnosis
To make accounting of items on hand; also. with people, to assess characteristics, skills, qualities, etc.
inventory
pharmacopeia
an authoritative listing of drugs and issues related to their use
Molecular particles that carry electric charges
ions
D5NS
5% dextrose in 0.9% sodium chloride
A variation of a drug that has the same molecular formula but a different arrangement of the atoms in the molecule
isomer
Pastes
ointment-like preparations for external application
When a solution has an osmolarity equivalent to that of blood
isotonic
D5RL
5% dextrose in Ringer's lactate
Important associated information that is not on the label of the drug product, but is provided with the product in the form of an insert, brochure, or other document
labeling
1987 Prescription Durg Marketing Act
state licenses
The tear ducts
lacrimal canalicula
D5W
5% dextrose in water elixir
The gland that produces tears for the eye
lacrimal gland
Creams
semisolid emulsions, containing suspensions or solutions of medicinal agents intended for external application
Continuous movement at a uniform rate in one direction
laminar flow
et
and
Any drug which requires a prescription and either of these "legends" on the label: "Caution: Federal law prohibits dispensing without a prescription," or "Rx only"
legend drug
What is a drug that binds to a particular receptor site and triggers teh cells response in a similar way to the bodys own chemical messenger?
Agonist
Triturating a powder drug with a solvent in which it is insoluble to reduce its particle size
levigation
ex aq
in water
Legal responsibility for costs or damages arising from misconduct or negligence
liability
Powders
finely divided, relatively dry, solid material intended for external application
A fat like substance
lipoidal
ft
make
A stabilizing agent for oil-based dispersion mediums
lipophilic emulsifier
1990 Omnibus Budget Reconciliation Act (OBRA)
pharmacist counseling
When drug activity is at the site of administration
local effect
g or gm or GM
Gram
drug names that have similar appearance, particularly when written
look-alikes
Gels and Jellies
two phase systems consisting of a solid internal phase diffused through out a viscous liquid phase
The hollow center of a needle
lumen
gal
gallon
A type of white blood cells that helps the body defend itself against bacteria and diseased cells
lymphocytes
pharmaceutical
of or about drugs; also, a drug product
Freeze-dried
lyophilized
GI
gastrointestinal
A medication that is required on a continuing basis for the treatment of a chronic condition
maintenance medication
Transdermal Patches
patches applied to the skin formulated to deliver a constant, controlled-dose of a medication through the skin and into the bloodstream
The difference between the retailer's sale price and their purchase price
mark-up
gr
Grain
General pharmacology, but also refers to the drugs in use
materia medica
1990 Anabolic Steroid Control Act
steroid abuse
OSHA required notices for hazardous substances that provide hazard, handling, clean-u, and first aid information
Material Safety Data Sheets
gtt
drop
The maximum price per tablet (or other dispensing unit) an insurer or PBM will pay for a given product
Maximum allowable cost (MAC)
Ophthalmic Drops
sterile solutions that are instilled into the eye in the form of an “eye drop”
A federal program, administered by the states, providing health care for the needy
Medicaid
H or hr
Hour
A federal program providing health care to perople with certain disabilities over age 65; it includes basic hospital insurance and voluntary medical insurance
Medicare
What is a drug that binds to a particular receptor site and blocks the action of teh endogenouschemical messenger without triggering the cells response called?
Antagonist
A form used to prescribe medication s for patients in institutional settings
medication order
hs
at bedtime
A form that tracks the medications administered to a patient
medication administration record (MAR)
Ophthalmic Ointments
sterile emulsions, properly formulated for application into the eye
A filter that attaches to a syringe and filters solution through a membrane as the solution is expelled from the syringe
membrane filter
hx
history
The curved surface of a column of liquid
meniscus
1996 Healh Insurance Portability and Accountability Act
right & privacy
The substance resulting from the body's transformation of an administered drug
metabolite
IM
Intramusclar
A unit of measure for electolytes in a solution
milliequivalent (mEq)
Medicated Contact Lenses
sterile contact lenses, pre-soaked with medication, inserted into the eye
Another term for an agonist, because agonists imitate or "mimic" the action of the neurotransmitter
mimetic
Inj
Injection
The blood concentration needed of a drug to produce a response
minimum effective concentration (MEC)
panacea
(panakeia-Greek)
a cure-all
The upper limit of the therapeutic window. Drug concentrations above the MTC increase the risk of undesired effects
minimum toxic concentration
IV
Intravenous
Capable of being mixed together
miscible
Ocular Inserts
drug pre-soaked inserts places in the lower eye sac between the sclera (white of the eye) and the eyelid
Computer hardware that enables a computer to communicate through telephone lines
modem
IVP
Intravenous push
The sum of the atomic weights of one moelcule
molecular weight
phase I
safety, 25% success
A wet, slimy liquid formed as an initial step in the wet gum method
mucilage
IVPB
Intravenous piggyback
Drugs that dilate the pupil
mydriatics
Suppositories
solid dosage forms for insertion into the rectum, vaginal cavity, or urethral tract
Heart attack
myocardial infarction
L or l
Liter
The muscular wall of the uterus
myometrium
What is dosage that causes interference with normal physiological functions, synonymous with poisonous effect called?
Toxic effects
The cavity behind the nose and above the roof of the mouth that filters air and moves mucous and inhaled contaminants outward and away from the lungs
nasal cavity
LR
Lactated Ringer's
A device which contains a drug that is vaporized by inhalation
nasal inhaler
Inhalers
solutions or suspensions of solid or liquid particles in gas or air intended for inhalation via nose or mouth
The cellular lining of the nose
nasal mucosa
N.F.
National Formulary
The number assigned by the manufacturer. The first five digits indicate the manufacturer. The next four indicate the medication, its strength, and dosage form. The last two indicate the package size.
National Drug Code (NDC)
phase II
effectiveness, safety
A unique, national, ten-digit, health care provider identification number, required for all HIPAA regulated claims submissions effective May 23, 2007
National Provider Identifier (NPI)
Noct
at night
The death of cells
necrosis
Otic Product
solutions suspensions instilled into the ear canal
Failing to do something that should or must be done
negligence
non rep.
Do Not repeat
The functional unit of the kidneys
nephron
antitoxin
a substance that acts against a toxin in the body; also a vaccine containing antitoxins, used to fight disease
The ability of a substance to harm to kidneys
nephrotoxicity
NPO
nothing by mouth
Chemicals released by nerves that interact with receptors to cause an effect
neurotransmitter
Enemas
liquid medications introduced into the rectum via a bulb syringe
A system of names specific to a particular field
nomenclature
NR
No refill
A chart showing relationships between measurements
nomogram
phase III
doseage, safety, effectiveness
Drugs not on the formulary which the physician can order; a physician can order; a physician may have to fill out a form stating why that particular drug is needed
non-formulary
NS
Normal saline (0.9% sodium chloride)
The top of left number in a fraction that indicates a portion of the denominator to be used
numerator
Douches
aqueous solutions which are directed into the cavity of the body
A federal act that is generally credited for states mandating pharmacist counseling on all new prescriptions
OBRA '90
NTG
Nitroglycerin
An obstruction of the bile excretion process
obstructive jaundice
Responses other than the primary therapeutic effect for a drug that can be beneficial or harmful are called what?
Side effects
An emulsion in which oil is dispersed through a water base
oil-in-water emulsion
N/V
nausea and/or vomiting
The resolution of prescription coverage through the communication of the pharmacy computer with the third party computer
online adjudication
Unit Dose Drug Distribution
allows for less preparation time for nursing to administer medications and increase the time for direct patient care
The time MEC is reached and the response occurs
onset of action
o.d.
right eye
A system that allows the pharmacy to purchase any medication that is prescribed
open formulary
OTC
over the counter
The time MEC is reached and the response occurs
onset of action
o.l.or o.s.
left eye
A system that allows the pharmacy to purchase any medication that is prescribed
open formulary
Medical Administration Records
are provided by pharmacy to each nursing unit which allows for a coordinated and verifiable means of drug distribution
The resolution of prescription coverage through the communication of the pharmacy computer with the third party computer
online adjudication
o.u.
Both eyes
The time MEC is reached and the response occurs
onset of action
antibiotic
a substance which harms or kills microorganisms like fungi and bacteria
A system that allows the pharmacy to purchase any medication that is prescribed
open formulary
"p"
after
Related to the eye
ophthalmic
Centralized unit dose system
where the majority of medications are prepared and dispensed from one central location
The common name for the FDA's Approved Drugs Products
Orange Book
p.c.
after meals
A drop in blood pressure upon standing up
orthostatic hypertension
Combat Methamphetamine Epidemic Act (CMEA)
3.6 g per day per purchaser
A unit of measure of osmotic pressure expressed in terms of osmoles (Osmol) or milliosmoles (mOsmol) per liter
osmolarity
p.o.
By mouth
The action in which a drug in a higher concentration solution passes through a permeable membrane to a lower concentration solution
osmosis
Decentralized Unit Dose System
where one or more “satellite” pharmacies are dispersed throughout the institution
A characteristic of a solution determined by the number of dissolved particles in it
osmotic pressure
pr
Per rectum
Medications that do not require a prescription
OTC drugs
A harmful, undesirable side effect
Adverse effects
A pharmacy attached to a hospital servicing patients who have left the hospital or who are visiting doctors in a hospital outpatient clinic
outpatient pharmacy
p.r.n.
as needed
A cure-all
panacea
Coding
refers to the notation on the medication order by a pharmacist or pharmacy technician of the name, strength and dosage form of the medication prepared for the patient
A route of adminstration to any organ outside of the alimentary tract(e.g. ophthalmic, dermal)
parenteral
pulv
Powder
The movement of drugs from an area of higher concentration to lower concentration
passive diffusion
NDC - National Drug Code
1 - manufacturer [4-5 digits]
2 - medication (strenght,dosage form) [3-4 digits]
3 - package size [2 digits]
Manufacturer sponsored prescription drug progams for the needy
patient assistance programs
q.
every
A fully functioning computer the size of a paperback book that could store thousands of contacts, appointments, and notes.
personal digitial assistant (PDA)
Automatic Stop Order
those medications that have a predesignated duration of therapy and must be discontinued if the physician has not ordered them and are determined by the Pharmacy and Therapeutics Committee
Having to do with the treatment of children
pediatric
hormone
chemicals produced by the body that regulate body function and processes
The absorption of drugs through the skin, often for a systemic effect
percutaneous absorption
q.d.
everyday
A system that maintains a continuous record of every item in inventory so that it always shos the stock on hand
perpetual inventory
Expiration date
the last date of the sale as determined by the manufacturer
To assess one;s personal characteristics, skills, qualities, etc
personal inventory
q.h.
every hour
The pH scale meausres the acidity or the opposite (alkalinity) of a substance, 7 is the neutral midpoint of the scale, values below which represent increasing acidity, and above which represent increasing alkalinity
pH
DEA Formula
2 letters - 7 digits
(1+3+5) + 2(2+4+6) = number with same last digit as DEA #
Of or about drugs; also, a drug product
pharmaceutical
q.h.s.
every bedtime
Drug products that contain the same active ingredients, but not necessarily in the same amount or dosage form
pharmaceutical alternative
What is the (OOA) Onset of Action?
The time period required after administration of a drug to achieve the desired response, or therapeutic concentration level.
Drug products that contain identical amounts of the same active ingredients in the same dosage form
pharmaceutical equivalent
q.i.d
Four times a day
A new field of study which defines the hereditary basis of individual differences in absorption, distribution, metabolism, and excertion (the ADME processes)
pharmacogentics
Schedule I
high potential for abuse - no accepted medical use
illegal drugs
Derived from the Greek words _pharmkon" or drug and "gnosis" or knowledge; the study of physical ,chemical, biochemical and biological properties of drugs as well as the search for new drugs from natural sources
pharmacognosy
q.o.d
every other day
The study of drugs - their properties, uses, applicatgion, and effects
pharmacology
human genome
the complete set of gentic material contained in a human cell
An authoritative listing of drugs and issues related to their use
pharmacopeia
q.s.
sufficient quantity
Companies that administer drug benefit programs
pharmacy benefit managers
Schedule II
high potential for abuse - currently accepted medical use - no refills - time & quantity limits
amphetamines, opium, cocaine, methadone, opiates
Small volume solutions added to an LVP
piggybacks
q.s. ad
a sufficient quantity to make
An inactive sustance given in place of medication
placebo
Unusual or unexpected responses to a drug, unrelated to the dose given
Idiosyncrasy
A system which shuttles objects through a tube using compressed air as the force; commonly used in hospitals for delivery of medication
pneumatic tube
R/O
Rule out
An inventory system in which the item is deducted from inventory as it is sold or dispensed
point of sale (POS)
Schedule III
potential for abuse - currently accepted medical use
anabolic steroids, limited amounts of codeine
Documentation of required policies, procedures, and disciplinary actions in a hospital
policy and procedure manual
rt., R
Right
The position of the number carries a mathematical significance or value
positional notation
A local or general immune response in which the immune system overreacts to an otherwise harmless substance, initial response evokes memory storage
Allergy
A network of providers were the patient's primary care physician must be a member and costs outside of the network may be partially reimbursed
POSs
s.
without
Medical and pharmaceutical nomenclature is a system made up of these four elements
1. root words
2. prefixes
3. suffixes
4. combining vowels (C.V.)
Schedule IV
lower potential for abuse - currently accepted medical use
phenobarbital, chloral hydrate, methohexital
Medical science terminology is based on different ____ ______ in the body
organ systems
sec
Second
A modifying component of a term located before the othe components of the term
prefix
The longest name of a drug, giving the chemical makeup
Chemical name
A written order from a practictioner for the preparation and administration of a medicine or device
prescription
SL, sl
sublingual (underneath the tongue)
Cards that contain third party billing information for prescription drug purchases
prescription drug benefit cards
Schedule V
lowest potential for abuse - currently accepted medical use
limited amounts of codeine
The initial emulsion to which ingredients are added to created the final product
primary emulsion
ss, s s (lines over each s)
One half
Original reports of clinical and other types of research projects and studies
primary literature
A shortened version of the chemical name
Generic name
An order for medication to be administered only on an as needed basis
PRN order
stat
immediately
An inactive drug that becomes active after it is transformed by the body
prodrug
Orange Book
Theraputic Equivalence
A = yes
B = no
Important associated information that is not on the label of a drug product itself
Product labeling
s.c. or s.q.
Subcutaneously (underneath the skin)
Offical publications of pharmacy organizations
professional practice journals
The name under which the manufacturer has patented the drug, copyrighted. This name begins with a capital letter
Trade or Brand name
Individuals who receive extensive and advanced levels of eduction before being allowed to practice, such as physicians and pharmacists
professionals
supp
suppository
The attachment of a drug molecule to ap;asma or tissue protein, effectively making the frug inactive, but also keeping it within the body
protein binding
Form 222
DEA from to order C-I & C-II
Specific guidelines for practice
protocols
Susp.
Suspension
A method for filling capsules by repeatedly pushing or "punching" the capsule into an amount of drug powder
punch method
The use of a drug for purposes other than those prescribed
Drug Abuse
The number assigned to each order for identification
purchase order number
Syr
Syrup
Chemicals produced by microorganisms that can cause pyretic (fever) reactions in patients
pyrogens
Class I recall
likely to cause serious injury or death
The quantity needed to make a prescribed amount
qsad
t.i.d
Three times a day
Medicare patients who may at times qualify for prescription drug coverage through a state administered program
Qualified Medicare Beneficaries
What are some symptoms of withdrawal syndrome?
restlessness and restless sleep, chill and hot flashes,piloerection on the skin, abdominal and lower extremity cramps, vomiting and diarrhea, muscular twitching, elevated blood pressure, pulse rate and temp, craving for the drug
The action taken to remove a drug from the market and have it returned to the manufacturer
recall
TPN
total parenteral nutrition
The cellular material at the site of action that interacts with the drug
receptor
Class II recall
temporary or reversable adverse effects
Minimum and maximum stock levels which determine when a reorder is placed and for how much
reorder points
U.d.
As directed
Absoprtion of bone elements into the blood
resorption
Means vinegar, acid or sharp
acet/o
A disease in which the body's immune system attachs joint tissue
rheumatiod arthritis
ung
ointment
The base component of a term which gives a word it meaning and which may be modified byother components
root word
Class III recall
not like to cause adverse effects
A child-resistant cap
safety cap
tr or tinct
tincture
Pharmacy locations in a decentalized system that operate outside the central pharmacy
satellites
Means glue
colloidal oatmeal
collo
A solution containing the maximum amount of drug it can contain at room temperature
saturated solution
USP
United State Pharmacopeia
What individuals may and may not do in their jobs
scope of practice
Means shape, dream
morph/o
Software that searches the Web for information related to criteria entered by the user
search engine
JCAHO
Joint Commission on Accreditation of Health Care Organizations
General reference works based upon primary literature sources
secondary literature
Means fever, fire
antipyretic
pyr, pyr/o
The characteristic of a drug that makes it action specific to certain receptors and the tissues they affect
selective (action)
ASCP
American Society for Consultant Pharmacists
The amount of weight that will move the balance pointer one decision mark on the marker plate
sensitivity
Means pain
-algia, -algesia
Needles, jagged flass or metal obhects, or any items that might puncture or cut the skin
sharps
Means to break apart
sympatholytic, urinalysis
-lysis
Stickers with bar codes that can be scanned for inventory identification
shle stickers
What is the chemical name of a drug dictated by?
The chemical components in the drug and the generic name is given when a compound is classified into a particular drug class.
Medication that will expire soon after preparation (i.e., within 1-6 hours after preparation)
short stability
How can drugs be identified by class?
When looking at the generic name
The direction for use on the prescription that must be printed on the prescription label
signa
Drug Class: benzodiazepine Ex:Diazepam
-azepam
A book in which patients sign for the prescription they, for legal and insurance purposes
signature log
Drug class: penicillin
Ex: amoxicillin
-cillin
The location where an administered drug produces an effect
site of action
nothing by mouth
npo
Drug class: narcotic analgesic
Ex:hydrocodone, codeine
-cod
When a drug is introduced into the circulatory system
systemic effect
A clear liquid made up of one or more substances dissolved in a solvent
solution
right eye
od
Drug class: beta blocker
Ex: atenelol propranolol
-olol
Individuals who are given a basic level of training designed to help them perform specific tasks
technicians
A liquid that disolves another substance in it
solvent
left eye
os
Drug class: steroid anti-inflammatory
triamcinolone
-olone
The ability of a substance to cause abnormal fetal development when given to a pregnant woman
teratogenecity
Exposure to high frequency sound waves
sonication
each eye or both eyes
ou
Drug class: ACE inhibitor
Ex: lisinopril monopril
-pril
Condensed works based on primary leterature such as textbooks, monographs, etc.
tertiary literature
Mixing powders with a spatyla
spatulation
Means by mouth
derived from per os
po
Drug class: H2 Blocker
Ex:ranitidine, cimetidine
-tidine
Serving to cure or heal
therapeutic
A device used to measure blood pressure
sphygmomanometer
Means rectally
pr
Drug class: tricyclic antidepressant
Ex:nortriptyline, amitriptyline
-triptyline
pharmaceutical equivalent that produce the same effects in patients
therapeutic equivalent
The chemical and physcial integrity of the dosage unit, and when appropriate, its ability to withstand microbiological contamination
stability
Means take or take thou
Rx
Drug class: antiviral
Ex: zivovudine
-vudine
A drug's blood concentration range between its minimum effective concentration and minimum toxic concentration
therapeutic window
A standard medication order for patients to receive medication at scheduled intervals
STAT order
What biological factors affect drug action?
Age, gender, disease state, psychological factors, genetic factors, and natural chemicals
Means drops
gtts
Applied for local effect, usually to the skin
Topical
A condition of excess fat in the feces
steatorrhea
Age related changes in organ funcion and body composition can causes altered drug responses in regards to what?
Absorption, distribution, elimination, metabolism
Means acetaminophen
APAP
A TPN solution that contains intravenous fat emulsion
total nutrient admixture (TNA) solution
A condition which is free of all microogranishs, noth harmful and harmless
steril
What are three natural chemicals yoru body produces that affect metabolism of drugs?
histamine, prostaglandin, and bradykinin
Means as needed
prn
Complex solutions with two base solutions (amino acids and dextrose) and additional micronutrients
total parenteral ntrition (TPN) solution
Means aspirin
ASA
What is release in your body as a result of the body's immune response to foreign substances?
Histamine
A thickening agent used in the preparation of suspensions
suspending agent
Journals published commerically for pharmacists but not produced by the profession; they tend to contain large amounts of advertising material
trade journals
The outermost cell layer of the epidermis
stratum corneum
Mediatores of several physiologic processes and produce diverse, complex pharmacologic actions in several body systems and metabolic pathways
(PG's) prostaglandins
Means four times a day
derived from quater in die
qid
Counter area designated for taking prescriptions and delivering them
transaction window
Derived from ante cibum means before meals
ac
What is a property of prostaglandins?
Fever and uterine contraction and relaxation
Formulations in which the drug does not completly disolve in the liquid
suspensions
Drug transfer into the eye
transcorneal transport
Under the tongue
sublingual
What causes intense uterine contraction?
PGF
Means three times a day derived from ter in die
tid
The process of grinding particles to reduce particle size
trituration
Means at pleasure, freely
ad lib
What causes uterine relaxation?
PGE,PGA, and PGB
When two drugs with similar pharmacological actions produce greater effects than the sum of the individual effects
synergism
The rate at which inventory is used, generally expressed in number of days
turnover
A modifying component of a term located after the other components of the term
suffix
A polypeptide that is formed from plasma alpha globulin?
Bradykinin
Right ear
ad
An infectious disease which promarily affects the respiratory system
tuberculosis
Means twice a day
BID
What are some effects of bradykinin?
Arterial dilation and lowered blood pressure, it stimulates autonomic ganglion cells in contact with sensory nerve ending, which causes pain
With chemicals, combining simpler chemicals into more complex compunds, creating a new chemical not found in nature as a result
synthetic
Usual and customary - the maximum amount of payment for a given prescription, determined by the insurer to be a usual and customary (and reasonable) price
U & C or UCR
A solution containing a larger amount of drug than it normally contains at room temperature
supersaturate solution
What happens if the gastro intestinal tract is free of food and irritating drugs?
Drugs are absorbed more rapidly
left ear
as
A package containing the amount of a drug required for one dose
unit-dose packaging
The ease with which a suspension can be drawn from a container in to a syringe
syringeability
What three phases is the mechanism of action divided into?
Pharmaceutical, pharmacokinetic, and pharmacodynamics
each ear or both ears
au
The price of a unit of medication (such as an ounce of liquid cold remedy)
unit price
850 grams of sucrose and 450 ml of water per liter
Syrup USP
In the pharmaceutical phase the process by which a drug goes into solution and becomes available for absorption is called what?
Dissolution
A standard claim form accepted by many insurers
universal claim form
In the pharmocokinetics phase what determines the rate of absorption?
The route of administration, dose of the drug, and dosage form.
A Web address
URL (uniform resource locator)
The transfer of a drug substance from a region of higher concentration to lower concentration until equilibrium is reached
Passive transport
The number of positive or negative charges on an ion
valence
No enery is required for theis process and the majority of drugs are transported by this system
Passive transport
A constriction of the blood vessels
vascoconstriction
Necessary for the transport of amino acids, glucose, and some drugs
Active or carrier transport
Drugs that relax and expand the blood vessels
vasodilators
Involves movement of drug molecules against the concentration gradient from lower concentration to higher concentration, or in the case of ions, against teh electrochemical potential gradient
Active or carrier transport
An unknown value in a mathematical equation
variable
Drugs that are lipid-soluble can also pass more easily through the ________,________, the placental barrier, and the alimentary tract
blood brain barrier
Irregular heart action seen in cardiac arrest patients
ventricular fibrillation
Which drugs are absorbed more quickly via the parenteral route?
Water-soluble
A small glass or plastic container with a rubber closure sealing the contents in the container
vial
Why may the drug be prepared in a vehicle that restists digestive action of the stomach contents?
to prevent nausea and vomition induced by the drugs effect in the stomach.
The thickness of a liquid
viscosity
(vi-skos-i-tee)
Storage reservoirs allow a drug to accumulate by binding to specific tissues in the body, which sustains teh pharmacologic effect of a drug at its point of action
Plasma protein binding
Meaures volume
volumetric
Where are lipid soluble drugs stored?
adipose tissue
The property of a substance being able to dissolve in water
water soluble
Where is the primary site of drug metabolism?
Liver
An emulsion in which water is dispersed through an oil base
water-in-oil emulsions
A process whereby drugs and pharmacologically active or inactive metabolites are eliminated from the body, primarily through the kidney
Excretion
Water molecules that attach to drug molecules
waters of hydration
Weak acids are excreted more ________in alkaline urine and more ________in acidic urine whereas as weak bases are excreted more________readily in acidic urine and more______in alkaline urine.
readily, slowly, readily, slowly
A raised blister-like area on the skin, as caused by an intrdermal injection
wheal
What is generally the safest route for drug administration?
Oral route
An employer compensation program for employees accidentally injured on the job
workers' compensation
The effects of two drugs given together is equal to the sum of each of teh individual drugs. 1+1=2
Additive effects (summation)
A collection of electronic documents at Internet addresses call Web sites.
World Wide Web
A drug interaction in which the combined effect of two drugs is greater thatn the sum of each individual dose. 1+1=3
Synergism
The administration o ftwo drugs is less than the sum of either drug given individually. 1+1=1.5 Both drugs compete for the same receptor site
Antagonism
An effect that occurs when one drug increases or prolongs the effect of another drug, but by itself has little or no effect
Potentiation
What is the only form alowed for prescribing controlled substances?
DD1289
What polyprescription can only be used for non controlled prescription or over the counter meds?
NAVMED 6710/6
What is the superscription?
The rX symbol
What is the inscription?
Lists name and quantities of the ingrediants to be used
What is the subscription?
Gives directions to the compounder
What is the Signatura?
Gives directions to the patient
How many times do you need to check the label when dispensing medications?
three
Where and when was the metric system developed?
France, 1790
When did the metric system become a legal standard measurment in the US?
1893