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29 Cards in this Set
- Front
- Back
Generally, how are Malarias treated?
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You try and prevent first, then you use the CDC data for the regional strains.
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What are the primary anti-malarials?
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Chloroquine
Primaquine Mefloquine Quinine (Severe Disease) |
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What is used to treat P. falciprum?
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Mefloquine, there is a lot of Chloroquine resistance
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What are the side effects of Chloroquine?
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Puritis, nausea, vomiting, malaise
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What is used popularly for Malaria prophylaxis?
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Mefloquine
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What are the side effects of Mefloquine?
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Siezures, sleep problems, arrhythmias
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What is used to treat the exoerythrocytic phase of malaria?
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Primaquine
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What are the side effects of Primaquine?
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Nausea, cramps, Rarely - hemolysys (G6PD deficiency) and arrythmeas
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What is used to treat tissue Amebiasis?
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Metronidazole
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What is used to treat luminal Amebiasis?
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Iodoquinol (DOC)
Paromomycin Diloxanide Furoate |
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What is used to treat African Trypanosomiasis?
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Hemolymphatic:
Pentamadine Suramin CNS: Melarsoprol Eflornithine |
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What are the drawbacks to the drugs used to treat Trypaosomiasis?
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They are extremely dangerous! Extreme fatigue nausea, vomiting, parastesia, nephrotoxic,
Pentamadine is Pancreaotoxic as well The CNS drugs can cause seizures, arthralgias, even death (Melarsoprol is the worst) |
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What is used to treat American Trypanosomiasis?
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Nifurtimox
Benznidazole |
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What is the draw back to these American Trypanosomiasis treatments?
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They are not effective against chronic stages
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What are the major side effects of Nifurtimox and Benznidazole
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Neuropathies, insomnia, seizures
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What is used to treat Leishmania?
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Sodium Stibogluconate
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What are the side effects of Sodium Stibogluconate?
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Fever, myalgia, arthralgia (flu-like) prolonged QT
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What are the drugs used to to treat Cryptosporidiosis?
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Nitazoxanide (only in good CD4 counts)
Paromycin Lactose-free diet, anti-motility agents |
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What are the drugs used to treat Giardiasis?
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Metronidazole (DOC)
Nitazoxanide |
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What is used to treat Toxoplasmosis?
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Pyrimethamine (combo with folinic acid, and clindamycin OR sulfadiazine)
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What drugs are used to treat helminthic infections generally?
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Albendazole
Mebendazole Ivermectin Praziquantel |
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What is particularly used to treat Neurocysticercosis?
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Steroids, Anticonvulsants, Albendazole (or Praziquantel)
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What is used to treat Trichanosis and Taeneasis?
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Mebendazole
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What are the side effects of Albenzazole?
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Minimal, late in treatment may see elevated LFT's and GI effects
Meaning it is safe in pregnancy |
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What are the side effects and contraindications of Praziquantel
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GI mostly
Contraindicated in ocular infections and pregnancy |
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What are the side effects and contraindications of Mebendazole?
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GI generally, hypersensitivity
Contraindicated in 1st trimester and under 2 years of age Interacts with Neuroleptics |
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What are the indications of Ivermectin?
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Strongylodiasis, Onchocerciasis
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What are the side effects and contraindications for Ivermectin?
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Not too many, hypersensitivity due to worm death
Contraindicated in pregnancy |
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What are the indications of DEC (diethylcarbamazepine citrate)
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Filarosis
Loiasis Tropical Eocinophillia W. bancrofti (with Iver) |