Pharmacology - Anemia Drugs

Front 1

In what kinds of anemia is Iron used to treat?

Back 1

Well Iron deficiency anemias! Really, though, blood loss anemias (menstruating), anemias caused by prematureity, anemias caused by absorption issues

Front 2

What are some of the side effects of oral Iron?

Back 2

Nausea, vomiting, black stool.

Front 3

What are some of the side effects of IV iron?

Back 3

Pain, tissue staining, fever, anaphylaxis (generally an option only if pt can't tolerate oral)

Front 4

What are some signs of B12 deficiency

Back 4

Atrophic glossitis, chronic gastritis, leucopenia with hypersegmented neutrophils. Common in gastric resection patients

Front 5

Why must you use B12 in B12 deficient patients and not Folate

Back 5

Because while it will reverse the anemia it will not help to treat sub acute combined degeneration

Front 6

Name three causes of folic acid deficiency.

Back 6

Pregnancy
Alcohol
Chemotheraputic Agents

These cause megaloblastic anemia

Front 7

What are the indications of erythropoietin (EPO)?

Back 7

Chronic renal failure
Aplastic anemia
leukemia
HIV/AIDS associated anemia
premature infants
post phlebotomy

Front 8

What are the side effects of EPO?

Back 8

Hypertension, DVT, progression of some tumors, anaphylaxis

Front 9

What are the indications of G-CSF or GM-CSF?

Back 9

Post chemotherapy
Congenital or cyclic neutropenia
Stem cell harvesting pre high dose chemo

Front 10

What are the side affects of G-CSF?

Back 10

bone pain, splenic rupture, anaphylaxis

Front 11

What are the side effects of GM-CSF?

Back 11

Fever, Arthralgia, Myalgia, Edema, Pleural Effusion, Anaphylaxis

Overall, G-CSF is preferred because of the severity of the side effects for GM-CSF above.

Front 12

What is the indication for IL-11 therapy?

Back 12

Thrombocytopenia post chemptherapy (usually if platelet transfusions are refractory)

Front 13

What are the side effects of IL-11 threapy?

Back 13

Fatigue, Headache, Dizziness, Atrial Arrythmia, Hypokalemia