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31 Cards in this Set

  • Front
  • Back

pathology

study of disease processes; structural & functional changes that cause or are caused by disease

etiology
cause of a disease; inherited or acquired
pathogenesis
mechanism of development; seq of events leading to disease
morphologic changes
structural changes in cells and organs
clinical significance
functional consequences of changes
inherited etiology
genetic defects
acquired etiology
infectious

chemical


nutritional


physical

gross changes
macroscopic, seen by naked eye
histologic changes
microscopic
pathognomonic
abnormality only found in one condition
sign
evidence of disease discovered by physician or abnormalities upon physical examination
symptom
patient's subjective observations
prognosis
expected outcome:

good = likely recovery


bad = permanent disability or death

general pathology
study of general reactions to insults and injuries that are basic to all disease processes
systemic pathology
study of specific disease processes as they effect certain organs and systems
applied pathology
anatomic

clinical


forensic

anatomic pathology
diagnosis by examination of tissues:

necropsy


surgical


cytopathology

necropsy pathology
study of cadavers to find causes(s) of death
surgical pathology
examination of excised tissues from living patients for diagnosis --> biopsy
cytopathology
study of individual cells (detect malignant cells)
clinical pathology
analysis of various patient specimens for diagnosis, therapy, and monitoring
forensic pathology
medicolegal investigation of death
biopsy
examination of tissue from living body for determination of existence or cause of disease: -closed

-open


-excisional

closed biopsy
needle or core biopsy:

-obtain material from mass via needle


-very small amount

open biopsy
incision made to obtain larger mass of tissue
excisional biopsy
mass or entire organ removed for diagnosis
FNAC
fine needle aspiration cytology:

thin bore needle used to obtain cells from superficial mass or deep mass lesions

surgical pathology methods
gross examination - fixation (formalin) - tissue processing, embedding & sectioning - staining - coverslipping - microscopic examination
gross examination
-determine the organ -determine what is wrong
hematoxylin staining
blue - nuclei, nucleoli, bacteria, calcium, etc
eosin staining
pink - cytoplasm, collagen, fibrin, colloid, etc