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152 Cards in this Set

  • Front
  • Back

Poultry

What is the definitive host of Eimeria tenella?

Gut epithelial cells

What cells do Eimeria tenella invade?

Oocyst or sporozoites

What stage of Eimeria tenella's life cycle is infective to the chicken?

Dysentery

What disease does Eimeria tenella cause?

Cat

What is the definitive host of Toxoplasma gondii?

Other mammals (humans)

What is the intermediate host for Toxoplasma gondii?

Oocyst or zoitocyst

What stage of Toxoplasma gondii is infective to the definitive host (cat)?

Toxoplasmosis

What disease does Toxoplasma gondii cause?

Enteroepithelial cycle

What stage of Toxoplasma gondii's life cycle occurs only in the cat?

Muscle


Brain


Lymph nodes


Macrophages

What other tissues can Toxoplasma gondii invade after the epithelial cells?

13% of the world and some reach 50%

What percent of the world is infected with toxoplasma gondii?

Flu like symptoms in humans

What are the symptoms of toxoplasmosis in humans?

Tachyzoite production

What phase of Toxoplasma gondii's life cycle occurs during the acute phase?

Yes

Is Toxoplasmosis transplacental?

Bradyzoite


Zoitocyst formation

What phase of Toxoplasma gondii's life cycle occurs during the chronic phase?

Cell mediated is most important


Humoral is slightly involved

What immune response is associated with toxoplasma gondii?

Yes

Can you get premunition from toxoplasma gondii?

No

Does toxoplasma gondii cause inflammation?

Bradyzoites can reactivate causing damage to brain, blindness, heart

What effect does Toxoplasma gondii have on immunocompromised people?

Cook meat


Freeze at -14 C for several hours kills zoitocysts


Clean litter box


Pregnant women should avoid cats

How do you treat and control Toxoplasma gondii?

Carnivores

What is the definitive host of Sarcocystis?

Herbivores

What is the intermediate host for Sarcocystis?

Cryptosporidiosis

What disease does cryptosporidium parvum cause?

Reptiles


Mammals


Birds

What are the hosts for Cryptosporidium parvum?

Gut epithellium and lungs

What cells do cryptosporidium parvum invade in the host?

Fecal contamination

How do humans contract cryptosporidiosis?

Diarrhea

In AIDs patients, what does cryptosporidiosis cause?

Lungs (extracellular)

What part of the body does Pneumocystis carinii invade?

Pneumocystis pneuomnia

What disease does Pneumocystis carinii cause?

Anopheles

What is the vector for all plasmodium?

Primates

What are the reservoir hosts for plasmodium?

Sporozoite

What stage of plasmodium life cycle is infective to the host?

Liver cells

What cells of the body do sporozoites of plasmodium invade?

Macro/microgametocytes

What stage of plasmodium life cycle is infective to the vector (Anopheles)?

Yes

Does plasmodium form a cyst?

Young red blood cells (reticulocytes)

What RBC's of the host does Plasmodium vivax invade?

Benign Tertian Malaria

What disease does plasmodium vivax cause?

48 hour cycle

How long does the infective cycle of plasmodium vivax take?

Relapses

What role do hypnozoites play in benign Tertian malaria?

43%

What percent of malaria causes is plasmodium vivax responsible for?

50%

What percent of malaria cases is plasmodium falciparum responsible for?

Malignant Tertian Malaria

What disease does plasmodium falciparum cause?

RBC's of all ages

What kind of RBC's do plasmodium falciparum invade?

2 nuclei

What makes the ring stage of plasmodium falciparum unique?

Plasmodium falciparum

What plasmodium forms "knobs" in RBC's?

Quartan malaria

What disease does plasmodium malariae cause?

6-7%

What percent of malaria cases is plasmodium malariae responsible for?

72 hour life cycle

How long is the life cycle for plasmodium malariae?

48 hours

How long is the life cycle for plasmodium falciparum?

Old RBC

What cells of the host does plasmodium malariae infect?

Mild Tertian Malaria

What disease does plasmodium ovale cause?

Plasmodium ovale

What parasite causes the mildest form of malaria?

Shed parasite antigens bind with RBC


TNF: spleen removes uninfected RBC


Defective bone marrow response


Loss of iron bound in hemozoin

How do the plasmodiums cause anemia?

Knobs of infected RBC bind with uninfected RBC and they all lyse

How does plasmodium falciparum ALSO cause anemia?

Feeling of intense cold


Nausea


Vomiting


Followed within 1 hour by high fever and intense back ache


Lasts 8-12 hours


Inflammatory response

What are the symptoms of diseases causes by plasmodium?

Plasmodium falciparum

What is the only plasmodium to have the symptomatic phase last longer than 8-12 hours?

Plasmodium falciparum

What plasmodium causes cerebral malaria?

Progressive headache followed by coma (80% death rate)


Temperature rises above 108


Hypoxia


Release of nitric oxide (may disrupt signals)

What are the symptoms of cerebral malaria?

Plasmodium falciparum

What is the only plasmodium that causes pulmonary edema?

Fluid in lungs (fatal)

What are the symptoms of pulmonary edema?

Plasmodium falciparum

What plasmodium that causes algid malaria?

Shock


Circulatory collapse


Low BP


Gastrointestinal hemorrhage


Septicemia

What are the symptoms of algid malaria?

Plasmodium falciparum

What plasmodium causes blackwater fever?

Lysis of RBC


Black urine


Renal failure


Vomitting


20-50% fatal

What are the symptoms of blackwater fever?

Yes

Can you get premunition from plasmodium diseases?

No

Is premunition of plasmodium diseases passed onto offspring?

2-3 months olds

At what age are infants completely immune to plasmodium diseases?

At weaning (when not supplied mother's milk)

When is immunity to plasmodium diseases lost in infants?

Humoral immune response


ADCC

What is the immune response to plasmodium sporozoites?

Cell mediated


Cytotoxic T Lymphocytes kill infected liver cells

What is the immune response for liver stages of plasmodium?

Humoral response

What is the immune response to the blood stages (merozoites) of plasmodium?

Antigenic variation


Shed surface antigens


Hemozoin uptake by macrophages


Polyclonal B cell activation


Decrease IL-2 production

How do the plasmodiums evade host immunity?

Sickle cell anemia has been selected for


Duffy blood groups

What is an evolutionary consequence of malaria?

Over production of proinflammatory cytokines


Higher IgE levels in hosts with severe malaria

What is the some ways the host immune system hurts the host when responding to plasmodium?

Fya or Fyb: susceptible to plasmodium vivax


FyFy: resistant to plasmodium vivax and partial immunity to plasmodium falciparum

What are examples of duffy blood groups?

Quinine

How do you treat plasmodium diseases?

Texas cattle tick fever

What disease does Babesia bigemina cause?

Boophilus annulatus

What is the vector of Babesia bigemina?

Vermicules (sporozoites)

What stage of Babesia bigemina's life cycle is infective to the definitive host (cattle)?

Macro/microgametocytes

What stage of Babesia bigemina's life cycle is infective to the vector?

Anchoring and penetration

What are the roles of polar filaments?

Whirling Disease causes fish to swim in circles

What is the name of the disease that Myxobolus cerebralis causes and what does it do?

Tubifex

What is the intermediate host of Myxobolus cerebralis?

Gut epithellium (anchor via polar filaments)

Where in the host does Myxobolus cerebralis reside?

Myxospores

What stage of Myxobolus cerebralis is infective to the definitive host (tubifex)?

Triactionmyxon

What stage of the life cycle of Myxobolus cerebralis is infective to the intermediate host (fish)?

Anchor to gut epithellium

What is the role of polar filaments when inside the tubifex?

Anchor and create opening

What is the role of polar filaments in the fish?

Erode cartilage and undergo repeated nuclear divisions

What is the role of the trophozoites of Myxobolus cerebralis once they migrate cartilage of the skull and spine?

Black tail and tail chasing in young salmonids

What disease does Myxobolus cerebralis cause?

Spinal and cranial deformities

What does black tail cause in fish?

Dwindling Disease (ass. With Colony Collapse Disorder)

What disease does Nosema apis and Nosema ceranae cause?

Spore

What stage of Nosema apis/cerenae is infective to the host (honey bee)?

Silk moth

What is the definitive host of Nosema bombycis?

Cyst

What stage of Balantidium coli life cycle is infective to the host(humans and pigs)?

Fecal contamination

How are the cysts of Balantidium coli transmitted?

Humans and pigs

What are the definitive hosts of balantidium coli?

Ick

What disease does Ichthyophthirius multifilis cause?

Swarmers

What stage of Ichthyophthirius multifilis life cycle is infective to the definite host (fish)?

Fish produce mucous in response to trophozoites attached to gills, causing the fish to suffocate itself

How does the immune system of the fish harm the host when responding to Ichthyophthirius multifilis?

Ick guard

What is the treatment for ick?

Oncomiracidium

What stage of Monogenoidea life cycles are infective to the hosts?

Monogenoidea Dactylogyrus

Irritates the gills


Fish produces mucous and suffocates itself


Attaches to gills

Monogenea Gyrodactylus viviparous

Occurs in the gills of fish


Irritate the gills


Eggs develop inside the body of the mother

Many embryos


(Offspring can be born pregnant)

Polyembryon

Creates Cytoplasm that goes to the surface and is constantly changed

Cytons

The cells of the epidermis are sunken below the surface

Sunken epidermis

Trematoda Digenea

What species of platyhelminthes have cytons?

Miracidium

What stage of Trematoda Digenea are infective to the 1st intermediate host?

Yes (sporocyst)(metacercaria)

Do Trematoda Digenea have cysts?

Metacercaria

What stage of Trematoda Digenea is infective to the definitive host?

Mesocercaria

An unencysted cercaria

Trematoda Digenea Alaria americana

What is the only horned fluke?

Canids

What is the definitive host of Trematoda Digenea Alaria americana?

Helisoma

What is the 1st intermediate host of Trematoda Digenea Alaria Americana?

Miracidium

What stage of Trematoda Digenea Alaria americana is infective to its 1st intermediate host (Helisoma)?

Fercocercous cercaria

What stage of Trematoda Digenea Alaria americana is infective to its second intermediate host (tadpole)?

Tadpole

What is the 2nd intermediate host in Trematoda Digenea Alaria americana life cycle?

Snake

What is the paratenic host of Trematoda Digenea Alaria americana?

Black spot in fish

What disease does Trematoda Digenea Uvulifer ambloplites cause?

Kingfisher

What is the definitive host of Trematoda Digenea Uvulifer ambloplites?

Helisoma

What is the 1st intermediate host of Trematoda Digenea Uvulifer ambloplites?

Some smaller Fish

What is the 2nd intermediate host of Trematoda Digenea Uvulifer ambloplites?

Primates

What is the reservoir host for Trematoda Digenea Schistosoma?

Human

What is the definitive host for Trematoda Digenea Schistosoma?

Helisoma

What is the 1st intermediate host of Trematoda Digenea Schistosoma?

Schistosomulum

What stage of Trematoda Digenea Schistosoma is infective to the definitive host?

Africa


Middle East


South America

Where is Trematoda Digenea Schistosoma mansoni prevalent?

Venules of the large intestine

What part of the body does Trematoda Digenea Schistosoma mansoni infect?

Trematoda Digenea Schistosoma mansoni

What Trematoda has an egg with a large lateral spine?

Biomphalaria

What is the intermediate host of Trematoda Digenea Schistosoma mansoni in Africa?

Tropicorbis

What is the intermediate host of Trematoda Digenea Schistosoma mansoni in South America?

Africa


Middle East

Where is Trematoda Digenea Schistosoma haematobium prevalent?

Venules of the urinary bladder

What cells of the body do Trematoda Digenea Schistosoma haematobium infect?

Trematoda Digenea Schistosoma haematobium

What Trematoda has an egg with a terminal spine?

Bulinus

What is the intermediate host of Trematoda Digenea Schistosoma haematobium?

Asian countries

Where is Trematoda Digenea Schistosoma japonicum prevalent?

Venules of the small intestines

What cell of the body do Trematoda Digenea Schistosoma japonicum infect?

Trematoda Digenea Schistosoma japonicum

What Trematoda has an egg with a small lateral spine?

Oncomelania

What is the intermediate host of Trematoda Digenea Schistosoma japonicum?

Swimmers itch

What does the penetration of non-human schistosome cercaria cause?

Initial phase of egg production


Eosinophilia


Fever


Gut complications

What are the symptoms of the acute phase of the diseases caused by Schistosoma?

Formation of pseudotubercles


DTH


Cirrhosis


Ascites


Splenomegaly

What are the symptoms of the chronic phase of diseases causes by Schistosoma?

Walls of the large intestine/liver


Cirrhosis


Ascites


Esophageal varicies


Haematomesis


Abdominal varicies

What do the Pseudotubercles of Trematoda Digenea Schistosoma mansoni cause?

Schistosomiasis

What is the disease caused by Schistosoma?

Walls of the small intestine/liver


Ascites


In brain


Most severe form is schistosomiasis


Paralysis


Coma


Dwarfism

What do the pseudotubercles of Trematoda Digenea Schistosoma japonicum cause?

Walls of bladder


Least severe form of schistosomiasis


Block ureter


Renal failure

What do the pseudotubercles of Trematoda Digenea Schistosoma haematobium cause?

Praziquantel


Control snails

What is the treatment and control for Schistosomiasis?

Antibodies against schistosomulum


ADCC


Eosinophils

What are the host responses to schistosomiasis?

Absorbs host ABO antigens


Sheds antigens


Cleave fc region of bound antibodies


Antioxidants


Polyclonal lymphocyte activation

How do Schistosoma evade host immune system?

Development requires CD4+ T cells


TNF stimulates egg production


Interleukins stimulate parasite growth


Granuloma formation movement of eggs across gut/bladder wall

How do Schistosoma exploit the host immune system?

DTH (inflammatory response)

How does the host immune system harm itself when responding to Schistosoma?