Obgyn Chapter 35 Puberty

Front 1

The event that triggers puberty is

Back 1

adequate sun exposure

Front 2

The hypothalamic-pituitary axis is first known to function

Back 2

in utero

Front 3

What is the first endocrine event associated with secondary sexual maturation?

Back 3

Secretion of dehydroepiandrosterone DHEA by the adrenal glands

Front 4

What is the usual length of time from the first physical signs of secondary sexual maturation until sexual maturation is complete?

Back 4

4 years

Front 5

What is the expected sequence of secondary sexual development in girls?

Back 5

Thelarche, adrenarche, growth spurt, menarche, ovulation

Front 6

Which of the following is required for timely secondary sexual maturation?

Back 6

Sufficient body fat AND sleep AND light

Front 7

What is the baseline percentage of body fat needed to sustain female reproductive function?

Back 7

24%

Front 8

What is the earliest sign of delayed puberty in girls?

Back 8

Failure of breast budding by age 13

Front 9

When adrenarche occurs first, what is the expected interval to the onset of thelarche?

Back 9

6 to 9 months

Front 10

Which of the following may cause premature sexual development in adolescent girls?

Back 10

Ovarian neoplasm

Front 11

What is the most common genital tract cause of primary amenorrhea?

Back 11

Imperforate hymen

Front 12

Which of the following is a method for treating vaginal agenesis?

Back 12

Pressure dilation of the vaginal space

Front 13

What is the simple, definitive treatment for imperforate hymen?

Back 13

Hymenotomy

Front 14

What is the definitive chemical evidence of ovarian failure?

Back 14

Elevated follicle-stimulating hormone FSH

Front 15

Genetic information that regulates the rate of ovarian follicular atresia is located on

Back 15

the long arm of the X chromosome

Front 16

Genetic information that determines height and somatic characteristics is located on

Back 16

the short arm of the X chromosome

Front 17

Which of the following hormones must be replaced in girls with premature ovarian failure?

Back 17

Estradiol-17beta

Front 18

What is the risk of administering excessive estradiol-17beta (or other estrogens) in girls with pubertal failure?

Back 18

Short stature

Front 19

What is the risk of delaying administration of estradiol-17beta in girls with pubertal failure?

Back 19

Osteoporosis

Front 20

Alteration of the gonadotropin-releasing hormone pulse frequency in adolescent girls will result in

Back 20

no pituitary stimulation of the ovary

Front 21

What condition is associated with olfactory tract hypoplasia and failure of gonadotropin-releasing hormone secretion?

Back 21

Kallmann syndrome

Front 22

What condition is associated with failure to establish secondary sexual development, a webbed neck, and short stature?

Back 22

Turner syndrome

Front 23

During clinical evaluation, Kallmann syndrome can be recognized by

Back 23

olfactory challenge

Front 24

How could a patient with Kallmann syndrome be treated to help her conceive?

Back 24

Pulsatile administration of gonadotropin-releasing hormone

Front 25

In adolescents, what would be evidence of incomplete puberty that is caused by marijuana use?

Back 25

Suppressed gonadotropins (FSH & LH)

Front 26

What is the prognosis for adolescent girls who have delayed puberty or secondary amenorrhea resulting from participation in competitive athletics?

Back 26

Normal secondary sexual development can be anticipated

Front 27

Isosexual precocious puberty is defined as

Back 27

premature sexual maturation following the normal sequence

Front 28

What is the most common cause of inappropriate hormone secretion leading to precocious puberty in girls?

Back 28

Adrenal hyperplasia, 21-hydroxylase type

Front 29

What is the treatment of choice for children with isosexual precocious puberty?

Back 29

Gonadotropin-releasing hormone

Front 30

Isosexual precocious puberty generally results in

Back 30

short stature

Front 31

A woman with uterine and vaginal agenesis can have her own genetic child through

Back 31

ovum donation

Front 32

Premature ovarian failure is characterized by

Back 32

lower estrogen level, elevated gonadotropin levels

Front 33

In patietns with premature ovarian failure, the daily dose of conjugated estrogen to initiate secondary sexual maturation is

Back 33

0.3 mg

Front 34

In patients with premature ovarian failure, the daily dose of conjugated estrogen to induce menarch is

Back 34

1.25 mg

Front 35

In patients with premature ovarian failure, induction of cyclic bleeding is accomplished with the cyclic administration of

Back 35

progestin