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370 Cards in this Set

  • Front
  • Back
Breast screen:

-ACOG
-USPSTF
ACOG: q1-2 yrs 40 --> q1 yr 50

USPSTF: q2yrs 50
OCP:

pregnancy rate (typical use)
3%
Increased osteoporosis:

-hyper- or hyperthyroid?
-parathyroid?
Hyper (both)
Hypothyroid: increase osteoporosis?
No

(unless o/d Synthroid)
Folate: increase or decrease homocysteine?
Decrease (good)
If pregnant woman has hyperhomocysteinemia --> admin what vitamin?
Folate
Folate supplement:

-normal preg
-h/o NTD
Normal: 400 MICROgrams

NTD: 4 MILLIgrams
Hemodilution of preg: peaks which week?
w36
MCV: increase or decrease?:

-iron def
-folate def
Iron: decrease MVC

Folate: increase
Physiologic dyspnea of preg: worse which TM?
TM3
Preg: increase or decrease:

-diaphragm excursion
-subcostal angle of diaph
Increase diaphragm excursion (elevates 4cm)

Increase angl: 68-103
Which tocolytic:

S/E PULMONARY EDEMA
TERBUTALINE
Terbutaline: beware which specific S/E?
Pulmonary edema
Normal preg: increase or decrease:

-HR
-SV
Both INCREASE

(increase 33% CO)
What % pregs have syst murmur?
95%
Progesterone: relax or contract SM?
Relax

(e.g. see ureter dil)
Normal preg: increase or decrease:

-TBG
-total T4
Increase (both)

(no change free T4)
What dz:

SNOWSTORM UTERUS
gest trophoblastic dz
If see snowstorm uterus --> order what other image?
CXR

(GTD --> #1 mets to lungs)
Another name for:

human placental lactogen
chorionic somatomammotropin
HPL: increase or decrease glucose uptake?
Decrease (i.e. anti-insulin)
Can glycosuria in preg be normal?
YES - increase GFR AND impaired tubular reabs
Cross placenta?:

-insulin
-glucose
insulin: NO (peptide)

glucose: yes via carrier-mediated
What tests to screen for Hgb abns?
CBC & electrophoresis
What genetic disease:

-most common in Mediterraneans
Beta-thal
Safe in preg?:

Valproic acid
No - NTDs, hydroceph, craniofacial malforms
Poorly-controlled IDDM --> what fetal malforms (2)
Cardio
NTDs
When perform:

CVS
10-12w
CVS: able to detect?:

-chromo abns
-NTDs
Chromo yes

NTDs no
CVS: % fetal loss?
1%
#1 inherited MR
Fragile X
COMBINED TEST (NT + PAPP-A + HCG):

-detect what % Downs?
-% FP?
85% Downs, 5% FP
Abn GTT (#s)
95 --> 180 --> 155 --> 140
BMI >30: limit how much wt gain in preg?
limit 10-20 lbs
Organogenesis: ends what week?
w8

(no risk teratogens if >8w)
Pt should RTC for r/o labor if:

-what freq cxns?
-what freq kicks?
1 cxn per 5 mins x 1hr

<10 kicks per 2h
Place IUPC --> significant vaginal bleed

-suspect what etio?
-next step?
Uterine perf

W/D --> monitor fetus --> reattempt IUPC
Midline or mediolateral episio:

More pain
Mediolat
Midline or mediolateral episio:

Less blood loss
MIDLINE
Midline or mediolateral episio:

Increased risk 3-4' tears
Midline
4th stage labor: how define?
0-2h postpartum
Which tocolytic:

S/E resp depress infant
Mg sulfate
Chorio: infant appears RED or PALE?
Pale
GDM: infant risks:

-hypo or hypergly?
-polycythemia or anemia?
-hypo or hyperbiliruin?
Hypogly
Polycyth
Hyperbilirubinemia
Infant w/out resp effort:

-what intervention? what position?
PPV (10L/min) in SNIFFING position (NOT flex)

(NOT suction - doesn't stim resp)
#1 etio PPH
Uterine atony (1:20 preg)
Sheehan: lose which hormones?
FSH
LH
TSH
ACTH
#1 etio post-partum fever
Endometritis
Endometritis:

-what % C/S?
-SVD?
10% C/S
1% SVD
Endometritis:

-which pathogens? (3 groups)
Staph
Strep
Anaerobes
Post-partum blues: what %?
40-80%
Should you prevent lactation with bromocriptine?
NO --> risk thromboembo --> CVA, HTN, szs
Breast-feed: supplement what vitamin?
IRON
Does breast milk contain adeq iron?
NO
Inhibit or promote milk production?:

-E
-P
Both inhibit alpha-lactalbumin -> inh PRL --> inh milk production
Why can woman not produce adeq milk d0-2?
High E & P --> inh PRL --> no milk prod
Sucking --> stim WHICH HORMONE?
Sucking --> stim OXY!!

(NOT PRL)
What dz:

Breast-feed --> burning nipples with PINK-SHINY PEEL
Breast candidiasis
Baby getting enough milk if:

-# stools/d
-# wet diapers/d
3-4 stools/d

6 diapers/d

wt gain, sucking sounds
Tx engorgement:

Loose or tight bra?
Tight
Tx engorgement:

Safe to admin analgesic before feed?
YES -- give 20 min before
Ectopic tx: able to use MTX if:

-what size (#) w/heart beat?
-w/out beat?
<3.5cm w/beat

<4cm w/out
Tx recurrent SAB: when place cerclage?
14w (TM2)
Does h/o surg abortion --> predispose to future SAB?
NO
What maternal dz:

Caudal regression syndrome
DM
DM:

see oligo or poly?
Poly
Safe in preg?:

Amitriptylline
Safe
(use to tx HAs)
Safe in preg?:

Lisinopril
No

S/E oligo, IUGR, neonate RF, pulm hypoplasia, joint contractures
Which anti-HTN in preg:

S/E joint contractures, pulm hypoplasia, IUGR/oligo
Lisinopril
HIV:

-when start po ZDV?
-when start IV?
po at 14w --> IV at L&D (regardless viral load)
#1 etio sepsis in preg
Pyelo
Safe in preg?:

Cromolyn
Yes
Acute asthma attack in preg --> admin leukotriene inh?
NO
-not useful acute
-unclear safety
Which White Class?:

Onset >20yo
B
Which White Class?:

Duration <10 yrs
B
Which White Class?:

Onset 10-19yo
C
Which White Class?:

Duration 10-19 yrs
C
Which White Class?:

Onset <10yo
D
Which White Class?:

Duration >20 yrs
D
Which White Class?:

Nephropathy
F
Which White Class?:

Retinopathy
R
What % mothers die in preg if:

Pulm HTN
25%
What % mothers die in preg if:

Ao coarct
25%
What % mothers die in preg if:

Marfan
25%
How tx: preg & obstructed ureter:

-initial
-after 72h
IVF + abx

if no improve: U/S w/double J stent
Breast cancer in preg: safe to admin:

-chemo?
-XRT?
Chemo yes

XRT no
Safe in preg?:

Paroxetine
No; cardiac malforms, pulm HTN
Which anti-dep:

S/E cardiac malforms, pulm HTN
Paroxetine
If suspect appendicitis in preg --> order what image?
Graded compression U/S
How protein in urine:

-mild preeclamp
-severe
Mild: >300 mg
Severe: >5g
Mg:

-therapeutic range
-lose DTRs
-Resp depress
-Cardiac arrest
Therapeutic: 4-7
Hyporeflex: 7-10
Resp depress: 12
Cardiac: 15
Severe preeclamp REMOTE FROM TERM: deliver if:

-plts < ___ (#)
-uncontrolled BP on ___ (#) meds
-LFTs increased by __x
Plts <100k

No control 2 meds

LFTs 2x
Severe preeclampsia: is delivery based on DEGREE of oliguira?
No
AFLP:

-develop ACUTE or INSIDIOUS?
INSID: days-weeks
What preg dz:

n/v; epigastric pain; progressive jaundice; VOMIT IN TM3; hypoglycemia
AFLP
AFLP: see increased or decreased:

-glucose
-BP
-fibrinogen
-albumin
-cholesterol
-clot time
Hypogly
HYPERTENSION
Hypofibrinogen
Hypoalbumin
HYPOCHOLESTEROL
Prolonged clot time
Severe preeclamp: goal DBP
90-100
What dz:

child given abx --> itchy vagina
Candida
Possible to perform SVE on child?
NO - always examine under anesth
Molar preg: more common WHITE or ASIAN?
ASIAN
Molar preg:

Assoc w/defs in which 2 vitamins?
Folate
B-carotene
Molar preg: ALL pts present w/what sign?
Painless vaginal bleed
Molar preg:

Assoc w/HTN? Obese? Parity?
No
Molar preg: see:

-maternal tachy or brady?
-mat hypo or HTN?
Tachy, HTN

(increase bHCG --> stim thyroid)
Molar preg:

D/C --> tx w/OCPs for how long?
OCPs x6mos
What mole type?:

Egg fertilized by disperm
Partial
What mole type?:


XXY
Partial
What mole type?:


XXX
Partial
What mole type?:

XYY
Partial
What mole type?:

XX
Complete
Invasive GTD: tx w/what modality?
CHEMO (easily cured)
Mole: low or high risk of recurrence?
Low (1-2%)
Choriocarcinoma: dx via bx?
NO - lesions are vasc --> met
#1 vulvar malig
SCC of vulva
Vulvar SCC: tx w/wide excision if:

<___ (diam) &
<___ invasion
<2cm diam + <1mm invasion
What VULVAR dz:

Elevated, firm, erythematous, ulcerated & itchy lesion
SCC
Vulvar SCC: assoc w/smoking?
YES

(esp HPV)
What VULVAR dz:

Assoc w/BREAST cancer
Paget's dz of vulva
What VULVAR dz:

fiery-red plaques w/lacy white mottling (NOT discrete mass)
Paget's dz of vulva
What VULVAR dz:

Cauliflower
Verrucous carcinoma
What VULVAR dz:

SHINY, non-pigmented papules w/central umbilication
Molluscum (poxvirus)
Trichloroacetic acid: txs what vulvar dz?
WARTS
(NOT VIN)
How tx:

- single VIN III
-multifocal
Single: Local supericial exicision
(NOT cryo, TCA)

Mult: CO2 laser ablation
Next step:

-ASCUS in <21yo
-ASCUS in >21yo
<21: Pap in 12mos
(NOT colpo)

>21: colpo OR Pap in 6mos
What Pap schedule in HIV+ pt?
initial Pap --> repeat 6mo --> annual
Next step:

HGSIL & visible lesion --> negative ECC --> ?
CONE BX
Next step:

CIN I w/positive ECC
Cone bx
Next step:

Pap w/adenocarcinoma in situ
Cone bx
Next step:

HGSIL --> "negative colpo bxs"
Cone bx
Relation to BM:

-CIN III
-CIS
-microinvasive cancer
CIN III & CIS: extend to BM but not beyond

Micro: 2-3mm beyond BM
#1 sxs fibroids
Menorrhagia (heavy scheduled bleed)
What dz:

14-16w sized uterus; heavy bleed; perimeno
Fibroids
Fibroids in preg: how tx?:

-small fibroid
-fibroids in LUS/cervix?
Small: no tx

LUS: may req C/S
Myomectomy:

-safe in preg?
-safe at C/S?
preg: no

C/S: NO - may increase blood loss
What fibroid type:

Most likely to cause infertility
Submucosal
What fibroid type:

Tx: hysteroscopic resect
Submucosal
Fibroids: max duration GnRH
3-6mos
Top 5 female cancers
1. Breast
2. Lung
3. Colorectal
4. Endometrial
5. Ovarian
#1 sx endometrial cancer
post-meno bled
What dz:

thin yellow discharge; abn post-meno bleed; lower abd discomfort
endomet cancer
If bx reveals endometrial cancer --> order what other image?
CXR
How tx:

-EARLY endometrial cancer
-High-grade/metastatic
Early: TAH-BSO + pelvic-paraaortic lymphadenectomy (BILAT) + washings

High-grade: omentectomy
Tamoxifen:

-increase what type cancer? automatic bx?
Endometrial

Only bx if BLEED/sx
Ovarian cancer:

-Whites or Blacks?
-Smoking?
W > B

NOT assoc smoking
Ovarian cancer:

OCPs in/decrease risk?
DECREASE (inhibit ovulation)
Ovarian cancer:

How dx mets/spread? (what image)
Abd/pelv CT

(only PET if KNOW mets or detect recurrence)
Ovarian cancer:

What 2 chemo agents
Cis-plat
Taxane
Ovarian cancer:

Is px correl w/tumor stage?
YES
Feto-maternal hemorrhage: usually how many cc's? enough to sensitize mother?
<0.1cc

Enough to sens
Best test to detect fetal ANEMIA
MCA peak syst velocity
Fetal hydrops: see poly/oligo
Poly
Admin how much Rhogam to neutralize 30 cc fetal blood?
300 ug
TTTS: what type of twins
Monochorion, monoamnion
DeltaOD: suspect erythroblast fetalis if what spectrum?
420-460nm
Liley curve:

-detect what comp?
Erythroblastosis fetalis

(via deltaOD)
Zone 3 of Liley curve:

-IUFD w/in how many days?
-how tx?
7-10d

IU transfusion OR delivery
What % deliver PRETERM:

-twins
-tirplets
-quads
50% twins

90% trips

100% quads
SAb: most common ANEUPLOIDY
Trisomy 16 (!!!)
What gest age:

Greatest risk M.R. & microceph
8-15w
Factor V Leiden: affect risk of:

-preeclam?
-stillbirth?
-abrupt?
Yes -- increase all
If 1 twin dies (not delivered) --> order what bi/weekly tesT?
FIBRINOGEN

(risk coagulopathy)
Name for:

Overlapping fetal skulls --> suggests IUFD
Spaulding sign
Spaulding sign: what is it?
Overlapping fetal skulls (suggest IUFD)
How tx:

-Arrest in LATENT phase
-Arrest of dilation in ACTIVE phase (3 steps)
Latent: rest or pit

Active: AROM --> pitocin --> place IUPC
Affect position?:

-Previa
-Fibroids?
Both lead to BREECH
How define: prolonged latent phase in:

-nullip
-multip
Null: >20h
Multip: >14h
Arrest in latent phase: can you AROM?
NO -- increase infxn
How define: secondary arrest of dilation
no change cervix 2h
How tx:

Previa near-term & 2nd bleed
C/S
What blood replacement product:

Fibrinogen + V + VII
FFP
What blood replacement product:

Fibrinogen + VIII + vWF
Cryo
Contains which factors:

-FFP
-Cryo
FFP: fibrinogen + V + VII

Cryo: fibrino + VIII + vWF

(NEITHER CONTAIN RBCs, plts)
vWD: admin which replacement product?
CRYO

(fibrino + VIII + vWF)
Smoking: increase risk macrosom?
NO --- incresae IUGR
Threatened Ab: more common TM1 or 2?
1
How tx:

Cxns + no cervical change
OBS
(50% preterm cxns spont resolve)
(do NOT admin steroids; not labor)
Which tocolytic contraindicated?:

DM (2)
Terb
Ritodine
Which tocolytic contraindicated?:

Myasthenia Gravis
Mg
Which tocolytic contraindicated?:

>33w
Indomethaicn
Indomethacin: do not administer (tocolytic) after what age?
>33w
Terbutaline: contraI in what dz?
DM
Ritrodine: contraI in what dz?
DM
Mg sulfate: contraI in what dz?
Myasth gravis
Which tocolytic:

Competes w/Ca for entry
Mg
Which tocolytic:

Increases cAMP
Terb/ritro
Terbutaline: mxn of action?
Increase cAMP --> decrease Ca+
Which tocolytic:

Inhibits Ca2+ transport
Nifedipine
Which tocolytic:

Blocks prostaglandin prod
Indomethacin
Which tocolytic:

S/E fetal hypoxia, decrease uteroplacental BF
Nifedipine
Do steroids affect risk of intracerebrla hemorr?
DECREASE
Terbutaline: contraI in what dz?
DM
Ritrodine: contraI in what dz?
DM
Mg sulfate: contraI in what dz?
Myasth gravis
Which tocolytic:

Competes w/Ca for entry
Mg
Which tocolytic:

Increases cAMP
Terb/ritro
Terbutaline: mxn of action?
Increase cAMP --> decrease Ca+
Which tocolytic:

Inhibits Ca2+ transport
Nifedipine
Which tocolytic:

Blocks prostaglandin prod
Indomethacin
Which tocolytic:

S/E fetal hypoxia, decrease uteroplacental BF
Nifedipine
Do steroids affect risk of intracerebrla hemorr?
DECREASE
FFN:

-normal in first 1/2 preg?
-indicates feto-mat injury at which week?
NORMAL in first 1/2

22-34w: feto-mat injury
FFN: low or high NPV?
HIGH NPV (99%)

-if neg --> baby will not deliver in 14d
Role of steroids controversial at how many weeks?
>32
Goal of tocolysis in PROM?
Admin steroids

(NOT prolong preg)
#1 risk PPROM
Infxn (esp BV)
PPROM at 28-34 weeks: what % will be in labor:

-w/in 24h
-w/in 48h
24h: 50%

48h: 80%
PPROM: abx can prolong preg how many days?
5--8d
Amnio in chorioamnionitis: increase or decrease:

-AF glucose
-IL-6
glucose: decrease

IL-6: increase

(presences of WBCs has LOW PPV)
h/o PPROM --> affect risk future PPROM?
YES - 30% recurrence
Methylergonovine: use?
Uterotonic (induce labor)
Which uterotonic agent contraI:

HTN, preeclamp
Methylergonovine:
Which uterotonic agent contraI:

Asthma
PGF2
Affect risk of retained placenta?:

-prev curretage?
-fibroids?
-parity?
-circumvallate placenta?
-pitocin use?
Increase risk: curretage, fibroids

No: parity, cicumvallate, pit
How tx:

uterine atony s/p oxy
IM PGF2
How tx:

Uncontrolled PPH
Hypogastric ligation --> THEN hyst (last resort)
Hyperthyroid: how affect menses?
Freq & irreg
Next step:

known genital warts + ASCUS
HPV-type

(determine if high-risk type)

THEN proceed colp or repeat 6mo
What dz:

Thayer Martin media
Gonorrhea
What dz:

Darkfield
Syph
What dz:

NT, non-itchy vulvar plaques; brown rash on palms & soles
Condyloma lata (SYPHILIS)
What dz:

Condyloma lata
Syph
Syphilis: are plaques tender/itchy? contain spirochetes?
NT, non-itchy

YES - contain spirochetes
What dz:

yellow, FROTHY discharge
Trich
What dz:

strawberry cervicitis
Trich
What dz:

PMNs w/multicelll giants
Herpes
HSV: what is GOLD standard dx?
culture
(10-20% FN)
(better than Ab)
Endometritis: mono/poly? an/aer?
Poly, mostly ANAEROBES
Endometritis: admin abx for how long?
Until 24h afebrile
Endometritis: which abx?
Gent + amp
What POST-PARTUM complication?:

Spiking high fever + non-responsive to abx
Septic thrombophlebitis
Septic thrombophleb: responds to abx?
No
Septic thrombophlebitis: low or high fevers?
Spiking high
What POST-PARTUM complication?:

Wound w/GRAY EDGES
Nec fasc
How tx:

Septic thrombophlebitis
abx + (ST) anticoag
What rating (A-X):

Human studies --> ok in preg
A
What rating (A-X):

Animal studies --> ok in preg
B
What rating (A-X):

Animal studies --> bad
C
What rating (A-X):

Human studies --> bad
D
What rating (A-X):

NEVER IN PREG
X
Sertlaine: what CLASS of meds?
C (animal studies -> bad in preg)
Safe in BREAST FEED?:

SSRIs
Secreted but negligble effect --> SAFE
Premens Dysphoric Disorder: which mens PHASE?
LUETAL (NOT follicular)

imp to ascertain timing of sxs
Placenta sulfatase deficiency: leads to pre- or post-temr?
POST
Fetal adrenal HYPOplasia: leads to pre- or post-term?
POST
Post-term: how affect risk of preeclamp?
No change risk
How tx:

41-42w and NOT want induction
2x NST & AFI per week --> INDUCE if not reactive or decreased AFI
Amnioinfusion w/NS: how affect risk of:

-variable decels
-NICU admit
-meconium asp
Decels: DECREASE

NICU & meconium asp: no change
How tx:

Post-term & repetitive variable decels
AMNIOINFUSION

(regardless meconium status)
What dz:

Increase SYST:DIAST in umbilical artery
IUGR
IUGR: see increase or decrease SYST:DIAST in umbilical art?
INCREASED ratio
Which bacteria:

Leads to IUGR?
TRICK - no bact
IUGR: increased risk:

-anemia or polycythemia?
-polyhydramnios?
Polycythemia

IUGR does NOT increase risk of poly
C/S indications:

-BPD > ___ (#)
-DM + wt >___ (#)
-nonDM + wt > ___(#)
BPD >12

DM >4,000g

nonDM >4,500
Forceps or vacuum:

More vaginal lacs
Forceps
Forceps or vacuum:

Transient lateral rectus paralysis
Vacuum
Vacuum: see transient paralysis of which muscle?
Lateral rectus
What dz:

SYMM FETAL GROWTH RESTRICTION + polyhydramnios
Trisomy 18
Trisomy 18: see A/SYMM growth restrict? oligo/poly?
SYMM restrict
Poly
Abortion:

If 1st low-dose OCP leads to n/v --> how admin 2nd dose?
Intravag
OCPs: in/decrease risk of:

-endomet cancer
-ovarian
-breast
Decrease endomet & ovarian

Increase breast
BTL: how affect risk of:

-ovarian cancer
-endomet cancer
-endometriosis
-mens flow
DECREASE OVARIAN CA

No change others
Mirena: how affect risk of endomet cancer?
DECREASE
Estrogen patch: contraI if >___(lbs)
>200lbs
Which contraceptive:

increased risk thromboembo
PATCH
How tx:

septic abortion (any age)
abx + EVACUATE (never med abortion)
W/U of what dz?:

Russel viper venom time
Antiphospholipid synd
Antiphospholipid synd: what 3 labs to w/u?
Anticardiolipin Abs
PTT
Russel viper
Antiphospholipid synd:

-how tx?
-what success preg?
Hep + ASA

75% success
Medical or surgical abortion: higher blood loss?
MEDICAL!!
Abortion: when perform:

-manual vacuum
-D&C
-D&E
vacuum: <8
D&C: <16
D&E: 16-24
Next step:

Medical abortion --> heavy bleeding (hct 29)
D&C
What dz:

Thin gray discharge
BV
What dz:

Modified Amsel Criteria
BV
1. thin grey
2. whiff
3. clue
4. ph >4.5
What dz:

Vulva pain/itch + BLEEDING GUMS + wrist rash + ALOPECIA
Lichen Planus
Tx inpt or outpt?:

PID w/high fever
INPT
PVR:

-normal
-if >300 --> what dz?
Normal 50

>300 --> overflow incont
What type incontinence:

Urethral hypermobile
Stress
What type incontinence:

Urethral angle >30
Stress

(hypermobile)
Stress incontinence: how tx:

- hypermobile urethra
- intrinsic sphincter defect
Hypermobile urethra: Urethroplexy OR sling

Spincter defect: Urethral BULKING
Tx what underlying etiology of incont:

Urethroplexy
Stress 2/2 hypermobile urethra
Tx what underlying etiology of incont:

Sling
Stress 2/2 hypermobile
Tx what underlying etiology of incont:

Bulking
Stress 2/2 intrinsic sphincter defect
What dz:

Drain-pipe urethra; contin leak urine
Intrins sphincter defect --> stress incont
Tx what dz:

OXYBUTYNIN (anticholin)
Urge incont (detrussor instab)
Urge incont (detrussor instab): tx w/what drug?
OXYBUTYNIN
Surg repair CENTRAL & LATERAL cystoceles: fix which FASCIA to sidewall?
Pubocervical
Should you offer induction to WELL-CONTROLLED GDM?
yes -- 39-40w
Endometrioma: how appear on U/S?
COMPLEX cyst
Endometriosis: what labs/imaging to confirm?
Trick! none, req lap
Hemorrhagic cyst: how appear U/S? how tx?
COMPLEX or SIMPLE!

f/u U/S in 2 mos to r/o cancer
Next step:

Highly suspect ovarian torsion but normal Doppler -->
IMMED SURG

-normal Doppler does not mean no torsion
How tx:

Endometriosis & infertile
Clomiphene --> surg (if meds fail)
Next step:

Adolescent p/w chronic pelvic pain
DIAGNOSTIC LAP! --> r/o endometriosis & IUA

-do NOT use GnRH agonist in adol
How long use GnRH agonists in adolescents?
Trick! No use GnRH in adols
What dz:

Urinary urge, freq, dysuria, nocturia; chronic pelvic pain
Interstitial cystitis (chronic inflamm bladdeR)
What drug:

Suppresses mid-cycle FSH & LH
DANAZOL

(NOT GnRH agonst: dysreg HPA production of FSH/LH)
Mxn of action:

-GnRH agonist
-Danazol
GnRH agon: suppress HPA production of FSH/LH

Danazol: suppress midcycle LH/FSH
What dz:

Pelvic varicositis; fullness in vulva & legs; vaginal discharge
Pelvic congestion syndrome (2/2 high estrogen --> vasodil)
Low transverse skin incision: risk entrapment of which nerves?
Iliohypogastric (T12-L1)

Ilioinguinal (T12-L1)
Which nerve:

Sensation of GROIN & skin over PUBIS
Iliohypogastric
Which nerve:

Sensation of LABIUM & UPPER THIGH
Ilioinguinal
Next step: breast lump & FNA --> shows:

-clear fluid
-blood
Clear: f/u 2mos

Blood: mammo + excision bx
Breast cancer:

Is LAD tender or not? Mobile?
NONTENDER
FIRM/FIXED
Mastitis: tx w/which abx?
DICLOXACILLIN

(covers staph aureus)
(ERYTHRO if pen-resistant)
Next step:

Positive ECC
COLD KNIFE

(NOT LEEP)
Next step:

Cervical lesion extending into canal
COLD KNIFE
Next step:

Cannot remove IUD in office
HysterOSCOPY
Definitive tx of endometriosis
Hyst PLUS BSO
Radical hyst: txs what dz?
Cervical cancer
What genetic disorder:

Leads to premature ovarian failure
Partial deletions of ovarian chromosome
Partial deletions of X chromo:

Leads to what reprod dz?
Premature ovarian failure
What dz?:

Normal external genitals; no 2' sex; anosmia
Kallman syndrome
Kallman syndrome: how appear:

-ext genitals
-2' sex
Normal ext genitals
No 2' sex
Kallman syndrome: what defect?
Olfactory tract hypoplasia --> arcuate no secrete GnRH
Kallman syndrome: how tx?
Pulsatile GnRH
What dz?:

Olfactory tract hypoplasia --> arcuate no secrete GnRH
Kallman syndrome
What dz?:

Premature pulsatile GnRH
True precocious pubery
True precocious puberty:

-what underlying mxn?
-how tx?
mxn: premat pulsatile GnRH

tx: GnRH agonist
1' amenn: only w/u at what age?
>17yo
Premature ovarian failure: definition?
<35yo
What dz?:

Partial block conversion of 17-hydroxyprogest --> accum androgens --> early adrenarche
CAH - 21 hydroxylase type
21-hydroxylase deficiency: how present? how tx?
block conversion 17-hydroxyP --> accum androgens --> EARLY ADRENARCHE

tx: replace steroids
Granulosa cell tumor: elevate what hormone?
ESTROGEN
deus, -i (m.)
god
Hirsutism: tx w/what drug?
SPIRONOLACTONE

(aldosterone antagonist)
Due to E or P:

Proliferative endometrium
E
Due to E or P:

Secretory endomet
P
Anovulatory bleed: underlying etio? how tx?
Unopposed E --> proliferative endometrium

Tx: admin P --> secretory endomet
Leuprolide: why not use >6mo?
S/E osteoporosis
What dz?:

BOGGY UTERUS
ADENOMYOSIS
Which presents at later age?:

Endometriosis or adenomyosis?
Adeno
Fibroids: encapsulated?
NO

(well-circumscribed myometrial tissue)
Leiomyosarcoma: req how many mitotic figures/hpf?
>10
Pt w/pathologic fx:

-req DEXA to tx w/bisphosphonate?
-DEXA how often?
Tx w/out DEXA

DEXA q2-3y
PCOS: how affect LH:FSH?
INCREASE LH:FSH ratio
What drug:

Increase PRL --> 2' amenn
IMIPRAMINE
Imipramine: how affect serum PRL?
Increase PRL --> 2' amenn
Hypo or Hyper thyroid:

Increase PRL --> 2' amenn
HYPOthyroid
Hypothyroid: how affect serum PRL?
INCREASE PRL --> 2' amenn
Exercise-induced amenn:

-how affect FSH? estrogen?
-how measure estrogenization?
NO CHANGE FSH

Decrease estrogen

PROGEST CHALLENGE TEST (see if w/d bleed)
PMS: give what 3 vitamins?
A
B6
E
Txs what dz?:

McCall culdoplasty
uterine prolapse

(hyst followed by plication of US ligaments)
Txs what dz?:

Sacrospinous ligament suspension
Vaginal vault prolapse s/p hysterectomy

(also tx via abd sacral colpoplexy)
Txs what dz?:

Abdominal sacral colpoplexy
Vaginal vault prolapse s/p hyst

(also tx via Sacrospinous ligament suspension)
#1 risk vaginal vault prolpase
s/p hysterectomy
What nerves to bladder carry:

-Symp (hold pee)
-Parasymp (urinate)
-somatic
Symp: hypogastric (T10-L2)

Parasymp: Pelvic (S2-4)

somatic: pudendal
Imipramine txs what type of incontinence?
MIXED (urge & stress) - has anti-cholinergic & alpha-adrenergic props
Leads to what type of incontinence?:

Detrusor insuff
Overflow
Leads to what type of incontinence?:

Detrusor areflexia
Overflow
What type of incontinence?:

Constant urinary dribbling
Overflow
What type of incontinence?:

Tx with CHOLINERGICS (bethanecol)
Overflow incontinence (increase bladder contractility)
Screen recs:

Cholesterol
q5 45-75
Screen recs:

BG
q3 45+
Screen recs:

Thyroid
q5 50+
Screen recs:

Osteoporosis (no risks)
65
Retained placenta --> UTERINE INVERSION:

Admin WHAT DRUG?
HALOTHANE (relaxes uterus)

(once uterus returns position: stop halothane --> start pit)
Increased risk uterine inversion if placenta implants where?
FUNDUS
Raloxifene:

-drug class
-tx what problem?
SERM; txs bone loss

(NOT hotflashes)
How tx?:

Pt w/hotflashes but no want E
CLONIDINE
Clonidine: tx what problem?
Hotflashes

(alt to E)
Should you base estrogen replacement dose on FSH level?
NO
Necrotizing fasc: usu due ENDO or EXTOTOXINS?
ENDO

(unless S aureus: exo)
What pathogen:

FLESH EATING BACT
group A strep
Necrotizing Fasc: how monitor hemodyn? (2 invasive)
Central ven cath
Swan-Ganz
Nec Fasc: which abx?
Pen + gent + metro
How tx Staph Aureus infxn?
nafcillin
vanco
Normal lenghts of LATENT and ACTIVE PHASES:

-nullip
-multip
nullip: <20h, >1.2 cm/h

multip: <14h, >1.5
Arrested active phase: define
No dilation x2h
Anthropoid pelvis: predisp what position?
AntrOPoid --> OP
What pelvis type?:

AP diam > transverse
anthropoid