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105 Cards in this Set

  • Front
  • Back

Where is the liver located

- upper RUQ under diaphragm

What does the liver contain

- 1/10 total blood volume


- 1/2 total lymph

What type of circulatory system does the liver have

Hepatic portal

What is the function of the liver

- storing and secreting nutrients, hormones and bile

What is the liver

A large 4 lobed gland

What is the process of blood circulation to the liver


- enters hepatic portal


- blood goes through 2 capillary beds


- enters hepatic portal vein


- blood arrives and nutrients moves across liver

What are the cells of the liver

- hepatocytes

What does the liver consist of

- lobules (tube like structures consisting of many hepatocytes)

What is at the edge of each lobule

- small vein from the hepatic portal that brings nutrients rich blood from the digestive tract


- small artery bringing oxygen and lipid rich blood from the heart

What is the function of the kupffer cells

Ensure portal blood are free of bacteria and any foreign substances

What is the function of the liver in metabolism

- all absorbed carbohydrates and protein go through the liver


- store nutrients, use nutrients and convert one to another

Do fats enter the hepatic portal

- fats do not enter the hepatic portal circulation arriving at the liver via the hepatic artery

What is the function of the peritoneum, peritoneal cavity and mesentery

- contain and provide protection and support for the abdominal organ


- provide a pathway for blood, lymph for abdominal organs

TISSUE FOUND IN GI TRACT


Mucosa

- 3 layers


- inner most layer produces mucous


- layer of CT over smooth muscle

TISSUE FOUND IN GI TRACT


Submucosa

- CT


- contain blood vessels, nerve endings and lymph


- contains submucosal nerve plexus

TISSUE FOUND IN GI TRACT


Muscularis externa

- 2 layers of smooth muscle that contracts allowing food to move along GI tract


- contributes to food breaking down into smaller fragments

What regulates the activity of the muscularis externa

- myenteric nerve plexus

Nervous system of the digestive system

- has own nervous system


- control peristalsis

What nerve is in the digestive system

- vagus nerve


- extends from brain to thoracic cavity and abdominal cavities


- vagus nerve interacts with submucosal and myenteric plexus

What is the function of the nervous system in the GI tract

- movement of food along GI tract

ORAL CAVITY


Mouth

- large amount of normal flora


- portal of entry for microbes

ORAL CAVITY


Teeth

- 32 permanent teeth


- types of teeth: incisors, canines and molars

ORAL CAVITY


Gums and buccal regions

- pink, moist


- no bleeding or breaks

ORAL CAVITY


Tongue

- mixes food with saliva


- pushes food Nokia towards back of mouth

ORAL CAVITY


Lips

- good colour, moist no breaks

ORAL CAVITY


Salivary glands

- 3 types of glands


- produce saliva

ORAL CAVITY


Salivary glands - parotid

- located over the ear

ORAL CAVITY


Salivary glands - submaxillary

- alongside the mandible, along floor of mouth

ORAL CAVITY


Salivary glands - sublingual

- along floor of mouth

Pharynx

- located at back of throat

Epiglottis

- flap that closes over trachea


- preventing food from entering lungs

Esophagus

- tube structure that connects to the stomach


- one sphincter controls movement of food

Where is the stomach located

LUQ abdominal cavity

What are the 3 divisions in the stomach

- fundus, body, pylorus

Process of food moving through the stomach

- food enters stomach via cardio-esophageal spinster


- food is mixed and tossed around forming chyme


- chyme leaves stomach via pyloric sphincter

What does the stomach when empty resemble

- folds of tissue

What does mucosa secrete

- various products to aid in digestion


- alkaline, therefore aiding in protecting against HCL

Process of food through small intestine

- food enters small intestine via pyloric sphincter


- food leaves small intestine via ileocecal valve

What sort of structure is the small intestine

- long tube like structure

What are the 3 divisions in the stomach

- duodenum, jejunum, ileum

Types of tissue in the small intestine

- microvilli


- villi


- circular folds


Function:


Ensures diffusion of nutrients into capillaries

What are the divisions of the large intestine

- cecum, appendix, colon and rectum

Where does the large intestine extend from

- ileocecal valve to anus

What are the 4 regions of the large intestine

- ascending colon, rectum, transverse, descending colon, sigmoid colon

Where is the pancreas located

- behind the stomach, across the abdomen from the spleen to the duodenum

What is the function of the pancreas

-


- produces pancreas juice

What is the function of the gallbladder

To store bile

Where is the gallbladder located

- interior surface of the liver

how the oral cavity contributes to the break down of food

teeth and tongue work with salivary glands to break down food into small masses that can be swallowed

How is food propelled from the pharynx to the oesophagus

upper esophageal sphincter opens so that food can enter the esophagus

how the structure of the small intestine adds in the absorption process

- Microvilli are hairs that aid in absorption of nutrients


- These projections increase the surface area of the small intestine allowing more area for nutrients to be absorbed

What happens to water in the large intestine

It gets reabsorbed

Digestive processes


Ingestion

- taking food into mouth

Digestive processes


Secretion

Release of fluids, enzymes and hormones

Digestive processes


Motility

Peristalsis and segmentation

Digestive processes


Digestion

Breaks food down into smaller products


- chemical or mechanical processes

Digestive processes


Absorption

Moves food particles from small intestine into blood and lymph

Digestive processes


Elimination

Disposal of waste

What is peristalsis

Wave like contractions and relaxation of muscles within the wall of the small intestine

What is segmentation

Mixing and squeezing the food products back and forth. This results in sections of the intestine contracting and relaxing.

Cephalic phase


When does it occur


What is the process

- occurs in response to appetite


- thoughts, smells, tastes of food


- brain sends signal to vagus nerve stimulating smooth muscle contract


- stimulates mucous in stomach to begin secretion of enzymes

What happens in the oral cavity that sets of the processes of digestion

- chewing food releases saliva, food mixes with saliva, secreting salivary amylase


- chemical digestion breaks down polysaccharides to disaccharides


- beginning of carbohydrate digestion

Deglutition


Buccal phase

- food mixes with saliva forming a bolus.


- tongue forces bolus towards pharynx

Deglutition


Pharyngeal - oesophageal phase

- Peristalsis moves bolus onward


- bolus reaches cardio-oesophageal sphincter


- sphincter opens and bolus enters the stomach

Gastric phase


Process

- food enters stomach, receptors and sensitive to arrival of food


- stomach expands


- receptors produce gastrin


- begin release of various enzymes involved in protein digestion

How does the gastric phase contribute to mechanical breakdown

By mixing products in stomach

Process of food entering the stomach

- vagus nerve actions the muscularis externa. Causing it to contract.


- gastric juices are released


- bolus begins to mix, composition changes to semi fluid chyme


- chyme forced to pyloric sphincter


- small amounts of chyme enter duodenum


- stomach empties


- reduce of gastric juice


- vagus nerve decreases activity



Where are gastric juices and G cells what released from


What they contain

- released from glands located in stomach


- contain parietal cells and chief cells

Function of parietal cells

- secrete HCL and intrinsic factor. Beginning the process of protein digestion

What is the function of chief cells

Secrete pepsinogen which converts to pepsin for protein digestion

What is the function of G cells

To secrete gastrin

What is the function of gastrin

Enhance protein absorption

What has happened once mechanical digestion and chemical digestion has partly occurred
- chyme left in stomach
- partial chemical digestion of carbohydrates has occurred via salivary amylase
- no digestion of lipids

What enzymes does the small intestine contain

- brush boarder enzymes


- pancreatic enzymes

What must happen to food before absorption can happen in the small intestine

Nutrients must be broken down into their building blocks

Where do nutrients leave the small intestine to travel to liver

Blood, then travel to liver via hepatic portal

Where are lipids absorbed

- into lymphatic circulation

What protects the small intestine from the acid in the stomach

Bicarbonate that mixes with chyme

What is the function of the liver

Bile secretion

What does bile contain

Bile salts

What is the function of bile salts

Bile salts mechanically breakdown globules of fats and lipids into smaller particles

What does bile salt allow

Allows digestive enzymes to complete the digestion process

What controls the release of bile

Secretin and CCK

What breaks down polysaccharides

- pancreatic amylase breaks down polysaccharides into disaccharides

What breaks down disaccharides

Brush border enzymes

Where do the monosaccharides go once they’re in the small intestine

liver via hepatic portal vein

What is the process of protein breakdown

- pancreatic juice contains proteases


- broken down into smaller molecule chains of peptides


- brush boarder enzymes continue the process


- once into smaller state amino acids pass into blood


- travel to liver via hepatic portal vein

What is the process of lipid absorption

- bile salts mechanically breakdown lipids


- lipase continue process, chemically breaking them down into smaller products


- bypass the portal and enter the blood circulation and travel to liver via hepatic portal artery

How do lipids get to the liver

- they enter lymph vessels


- and get into blood circulation


- travel to liver via hepatic portal artery


Can lipids travel through water

- they are water phobic, they don’t move through blood easily and require assistance from lipoprotein transportation

Process of absorption of water

- H20 moves into cells and then blood

Process of absorption minerals

minerals absorbed via small intestine

Process of absorption water soluble vitamins

- water soluble vitamins absorbed via blood

Process of absorption fat soluble vitamins

- absorbed with lipids

Large intestine


Are there digestive enzymes

No

What enters the large intestine

Small amounts of h20 and fibre

What is absorbed from the large intestine

- h20

Rectum/elimination


Process

- faeces move into rectum via peristalsis and reflexes


- walls stretch


- anal sphincter relaxes


- faeces forced out of anal canal

What is absorbed from the large intestine

- h20

intestinal phase


- Protect the sensitive small intestine against incoming stomach acid through secretin - Prepare the liver for incoming nutrients


- Ensure there is enough time for digestion & absorption

What is biles contribution to lipid digestion

- bile mechanically breaks down fats and lipids into smaller particals

How does the pancreas contribute to chymes composition

- bicarbonate produced by the pancreas is mixed with chyme

How does the pancreas contribute to the composition of chyme

Bicarbonate mixes with chyme, changing pH to neutral

What is the breakdown process of carbohydrates

•starts in the mouth with saliva


- Pancreatic amylase breaks down any other polysaccharides into disaccharides


•Brush border enzymes break down disaccharides to monosaccharides


•monosaccharides pass through the intestinal walls into the blood


-in the blood they travel to the liver via the Hepatic Portal Vein

Difference between fat soluble and water soluble vitamins

- water soluble needed in small amounts and are excreted via urination


- fat soluble are stored in the body for a longer time