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24 Cards in this Set
- Front
- Back
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What are the 1st line choices for treating anxiety disorders?
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SSRIs (No longer Benzodiazepines)
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What would you use MAOIs for in regards to anxiety?
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Panic disorder
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What type of drug is Chlordiazepozide?
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Benzo
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What kind of drug is Oxazepam?
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Benzo
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What kind of drug is Diazepam?
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Benzo
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What benzos are best for anxiety?
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Those with a wider response curve
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What is the metabolism of benzos?
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To active metabolites
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What tests do benzos require for clearance?
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liver and kidney
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**What drugs would you give to someone to tx anxiety that has liver failure?
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Oxazepam, Temazepam or Lorazepam because they do not need the liver to be metabolized and can be conjugated in tissues other than the liver
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What drugs do you have to warn about use of machinery?
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Benzos (sedation effect)
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What substnace may benzos show cross tolerance to?
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Alcohol
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What can you give an alcoholic to stop their withdrawal?
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Diazepam
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What would the symptoms of a benzo withdrawal be?
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Anxiety, Insomnia, Irritability, muscle tension
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What category are benzos in pregnancy?
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D - Be careful!
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What is useful in a Benzo OD?
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Flumazenil
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What is the half life of Flumazenil?
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One hour
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What drug produces less psychomotor impairment than benzodiazepines (driving)?
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Buspirone
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What drug has little abuse potential?
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buspirone
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What drug shows significant skeletal muscle relaxation?
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Meprobamate
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What is the #1 choice for Generalized Anxiety Disorder?
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SSRIs
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What is the #1 choice for panic reactions?
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SSRIs
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What is marketed specifically to tx OCD?
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Fluvoxamine
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What is an antiseizure drug that has shown antispasmotic effects in MS?
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Gabapentin
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Where does Dantrolene work?
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Alters the excitation contraction coupling in skeletal muscle tissue; interferes with Ca release at SR
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