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20 Cards in this Set
- Front
- Back
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oncogene중 Burkitt lymphoma와 관련있는 것은?
c-myc c-abl bcl-2 ras |
c-myc : transcription factor
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Lymphoma 중 leukemic component가 있는것은? Reed-sterberg cell이 있는것은?
a. Hodgkin b. non-Hodgkin |
Leukemic - NH
RS cell - Hodgkin |
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colon carcinoma and G protein related oncogene?
c-myc c-abl bcl-2 ras |
ras
c-myc TF Burkitt lymphoma c-abl tyrosine kinase CML bcl-2 ihnibits apoptosis NH lymphoma ras Gprotein colon carcinoma |
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Which of following is tumor suppressor gene?
p53 c-myc c-abl ras |
p53
RB1 retinoblastoma BRCA-1 breast cancer and ovarian cancer p53 breast carcinoma, colon carcinoma, brochial carcinoma |
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Cytokine
APC(MQ)->IL1 -> T cell(CD4) activation --> becomes Th1 --> IL-2 and INF-r Il-2 : activate NK and B cell INF-r : activate MQ T cell -> Il-2,4,5 -> growth and differentiation of lymphocytes monocyte -> Il-6 , 8 Il-6 : growth and diff of lymphocytes Il-8 : chemotaxis and activation of neutrophils |
read
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Acute inflammation시 나오는 cytokine은?
a. IL-2 b. IL-3 c. TNF-r d. IL-8 |
d.
acute: A18 (TNF-a , IL-1 , IL-8) |
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T cell activation을 하는 IL?
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IL-1
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B cell activation IL?
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2,4,5
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Neutrophi chemotaxis IL?
a. Il-1 b. Il-2 c. Il-6 d. Il-8 |
Il-8
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T cell secrest which of following?
a. Il-6 b. Il-1 c. Il-4 d. Il-8 |
c.
T cell - Il 2,4,5 |
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Which of following T cell secrete?
a. INF-alpha b. INF-beta c. INF-gamma |
c.
INF-b : fibroblst INF-a : WBC |
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MQ secrets 2 cytokine?
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Il-1 and TNF-a(like Il-1)
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Il-7 is produced by ?
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bone marrow cell ( not lymphoid ts)
IL-7 : stimulating the proliferation of lymphoid progenitors |
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Il-3 is produced from where and do what?
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Il-3 from T-cell
stimulate Bone marrow |
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Multiple myeloma에서 나타나는 amyloid type?
a. AA b. AL |
b.
AA : chronic inflammation and aging AA(amyloid associated protein) AL(amyloid light chains) |
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Which cancer matastasize to bone most frequently?
a. Brest b. Lung c. liver d. brain |
a. Breat > lung
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Which cancer matastasize to brain most frequently?
a. Brest b. Lung c. liver d. brain |
b. lung > breast
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Which of following HLA type is related to IDDM?
a. A3 b. DR3 c. DR2 d. B27 |
DR3
DR2 : multiple sclerosis A3 : hematochromatosis B27 : Ankylosing spondylitis , Reiter's syndrome, Ulcerative colitis |
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Which of following HLA type is involved to Class II
a. A b. B c. C d. D |
d.
HLA-D : Class II |
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??which artery is affected by syphilitic aneurysm ?
a. Ascending aorta b. Descending aorta |
a.
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