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19 Cards in this Set
- Front
- Back
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Postpartum thyroiditis |
Associated with positive anti-TPO or anti-microsomal antibodies Most likely will become euthyroid eventually |
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Oncogenic osteomalacia |
FGF23 releasing tumour, which inhibits phosphate reabsorption Low Phos, raised ALP, low 1-25 VitD |
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Hypothyroidism in pregnancy |
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Autoimmune polyendocrine/polyglandular syndrome (APS) |
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Myxoedema coma |
IV hydrocortisone (because Addisonian crisis can co-exist) IV T3 Slow rewarming |
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Amiodarone-induced thyroiditis type 1 and 2 |
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Charcot joint |
Diagnosis: Indium labelled white cell scan Immobilisation for at least 3 months Bisphosphonate |
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Metformin-related diarrhoea |
Bile salt malabsorption - high dose Metformin is thought to interfere with the enterohepatic circulation of bile salts Can be avoided with slow up-titration of the dose |
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Pituitary adenoma |
GH secreting adenoma - somatostatin analog, 2nd line is surgery/pegvisomant
Prolactin secreting - dopamine agonist eg bromocriptine/cabergoline |
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Cold Vs hot nodule |
Hot nodules can be treated with radioiodine Cold nodules may need surgery especially if malignant |
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Craniopharyngioma |
Calcified cyst arising from remnants of the craniopharyngeal duct (CT head shows suprasellar calcified cyst) Growth failure/delayed puberty Headache |
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Causes of hypopituitarism |
Tumour Infection Inflammation - autoimmune or lymphocytic hypophysitis Infiltration - neurosarcoidosis, histiocytosis, excessive iron (haemochromatosis, excessive blood transfusion) Vascular - Sheehan's syndrome Radiation Trauma Congenital Toxin - Bites from Russell's Vipers |
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Acute intermittent porphyria |
Abdo tenderness during attacks, confused and hallucination, back and leg pain Hyponatremia Treat: IV dextrose, IV haem arginate |
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Pseudohypoparathyroidism |
Raised PTH but PTH receptor unresponsive Short stature Short metacarpals Subcutaneous calcification Intellectual impairment |
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Insulinoma |
Exercise provocation test after an overnight fast |
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Graves disease in pregnancy |
Propylthiouracil in first trimester Carbimazole in second and third trimester |
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Cranial diabetes insipidus |
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Cushing's syndrome |
Initial screening test - serum cortisol between 8pm and 11pm - 24hour urinary cortisol Definitive: dexamethasone suppression test |
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Subacute thyroiditis/de quervain |
Global decreased uptake Treat with NSAID |
