• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/318

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

318 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)

It causes a non-TB disease in AIDS and a prophylaxis with Azithromycin when CD4+ count is less than 50 cells/mm.

M. avium intracellulare

acid fast bacteria

What are the symptoms of TB? Name at least two.

fever, night sweats, weight loss, cough

It is caused by M. leprae that affects superficial nerves.

Hansen Disease/Leprosy

The lethal form of leprosy.

Lepromatous

Leprosy has two treatments for its two forms.



What is the DOC for its tuberculoid form and lepromatous form?

Dapsone and Rifampin for Tuberculoid form; Clofazimine is added for lepromatous form

A form of leprosy with little tissue destruction, and has a positive reaction with Lepromin skin test.

Tuberculoid leprosy

A tinea which occurs in inguinal area.

Tinea cruris

The hardest Tinea to treat that can be managed for at least 3 months. It occurs on nails.

Tinea unguium

A Tinea that occurs on hair, nails and skin.

Trichophyton

Dermophytes/Tinea such as Microsporum and Epidermophyton occurs both on skin. What is their difference based on occurrence?

Microsporum - hair


Epidermophyton - skin

A Tinea that occurs on head, and scalp that is associated with alopecia.

T. capitis

It has a "Spaghetti and Meatballs" appearance on microscopy and is caused by Malassezia spp.

T. versicolor

Treatment for T. versicolor

Selenium sulfide

Treatment for Rose Gardener's Disease

Itraconazole or Potassium Iodide

A dimorphic fungus that causes sporotrichosis and it exists as a cigar-shapes yeast at 37°C in human body.

Sporothrix schenckii

The only fungus that can form germ tubes.

Candida albicans

Candida albicans have different forms:



at 20°C it forms _______ and _______


at 37°C it forms ________

20°C = pseudohyphae and budding yeasts



37°C = germ tubes

It is a hypersensitivity response to Aspergillus growing in lungs that is associated with asthma and cystic fibrosis.

Allergic bronchopulmonary aspergillosis (ABPA)

It is a disc shaped yeast that is originally classified as protozoan. It is diagnosed by bronchoalveolar lavage or lung biopsy.

Pneumocystis jirovecii

It is used as a prophylaxis when CD4+ count drops to less than 20 cells/mm in HIV patients.

Pneumocystis jirovecii

Treatment for Pneumocystis jirovecii

TMP-SMX


Pentamidine


Dapsone

Histoplasmosis has a pathologic feature of a macrophage filled with histoplasma. It is endemic in ______.

Mississippi and Ohio

It is the predisposing factor of Histoplasmosis.

spelunking - bat or bird dropping

Blastomycosis has a broad-based budding of Blastomyces that is endemic in _________.

Eastern and Central US

A systemic mycoses that is endemic in California usually affects _________.

Filipinos

A spherule filled with endospores of coccidioides which is associated with dust exposure.

Coccidioidomycosis

It is endemic in Latin America that has a "Captain's Wheel" formation.

Para-coccidioidomycosis

A disease characterized by bloating, flatulence, foul-smell, and fatty diarrhea.

Gardiasis

A protozoa that causes Giardiasis.

Giardia lambia

A disease caused by Entamoeba histolytica.

Amebiasis

Amebiasis is a disease causes by Entamoeba histolytica is characterized by __________.

bloody diarrhea


liver abscess


flaske-shaped ulcer


anchovy paste

It causes severe diarrhea in AIDS.

Cryptosporidium

A donut shaped protozoa in acid-fast staining. It can be prevented by filtering water supplies.

Cryptosporidium

A free living amoeba that can be transmitted in warm freshwater. It can be treated with Amphotericin B.

Naegleria fowleri

It can cause rapidly fatal meningoencephalitis.

Naegleria fowleri

Trypanosoma brucei can be treated by _______ for blood-borne disease and _______ for CNS penetration.

blood - Suramin


CNS - Melarsoprol

A protozoa that has a transmission through a painful bite of a Tsetse fly.

Trypanosoma brucei

Congenital toxoplasmosis has a classic triad of:



1. chorioretinitis


2. _______________


3. _______________

hydrocephalus, intracranial calcifications

A benign plasmodium with a 48hr cycle. It is in dormant form (hypnozoite) in liver.

P. vivaxlovale

A malignant plasmodium that can cause cerebral malaria.

P. falciparum

A plasmodium that has a 72hr cycle of:



cold stage —> fever —> sweating

P. malariae

Transmission of Plasmodium is through ________.

Anopheles mosquitos

Transmission of Babesia is through _______.

Ixodes tick

It has a diagnosis of "Maltese cross".

Babesia

It causes Chagas disease.

Trypanosoma cruzi

A disease caused by Trypanosoma cruzi that is characterized by dilated cardiomyopathy that predominates in South America.

Chagas disease

Transmission of Trypanosoma cruzi is through ________.

Triatomine insect/kissing bug

Visceral leishmaniasis is characterized by spiking fever, hepatosplenomegaly, and pancytopenia caused by what kind of leishmania spp?

L. donovani

Cutaneous leishmaniasis is characterized by skin ulcers that is caused by what kind of leishmania?

L. brazillensis

Treatment for Trypanosoma cruzi

Benznidazoles

Treatment for Leishmania spp.

Na stibogluconate


Amphotericin B

Vaginitis is characterized by foul smelling, greenish discharge, itching, and burning. What organism is responsible for this?

Trichomonas vaginalis

A type of helminth that is almost treated with Bendazoles except Strongyloides stercoralis

Nematodes/Roundworms

Treatment for Strongyloides stercoralis.

Ivermectin

It is transmitted by fecal-oral route which can cause anal pruritus.

Enterobius vermicularis

A type of nematode that is most common in the Philippines that causes ileococal obstruction, intestinal perforation which migrates from nose/mouth.

Ascaris lumbricoides

It is transmitted by a larvae that can penetrate the skin which causes microcytic anemia.

Ancylostoma spp.

It is transmitted through undercooked meat that causes Trichinosis which is characterized by periorbital edema and myalgia.

Trichinella spiralis

It is often asymptomatic and causes rectal prolapse in children.

Trichuris trichuria

It is transmitted by a female black fly and treated by Ivermectin.


"black skin nodules, black sight"

Onchocerca volvulus

A worm in conjunctiva transmitted by Deer, Horse, and Mango fly.

Loa loa

It is common in abaca workers transmitted by female mosquito that invades the lymph nodes.

Wuchereria bancrofti

2 nematode (tissue) treated with Diethylcarbamazine.

Loa loa and Wuchereria bancrofti

Intermediate host of Schistosoma

snails

A type of Schistosoma that can cause liver and spleen enlargement.

S. mansoni

The chronic infection of S. haematobium can lead to _______.

squamous cell carcinoma of the bladder

Trematodes are treated with ________.

Praziquantel

An organism transmitted in undercooked fish that can cause biliary tract inflammation.

Clonorchis sinensis

Tinea solium transmitted by ingestion of larvae in undercooked pork caused what disease?

Intestinal tapeworm

Tinea solium transmitted by ingestion of egg in food contaminated with human feces can cause what disease?

cysticercosis

A cestode that can cause Vit b12 deficiency that it is transmitted by ingestion of larvae in raw freshwater fish.

Diphyllobothrium latum

A disease caused by Echinococcus granulosus. It is also known as "egg shell calcification".

Hydatid cysts

It transmitted by ingesting of eggs in food contaminated with dog feces.

Echinococcus granulosus

A cestode that is treated with Albendazole and its immediate hosts are sheep.

Echinococcus granulosus

T or F



Retrovirus cannot replicate in the cytoplasm.

True.


All RNA viruses can replicate in the cytoplasm except Retrovirus and Influenza virus.

Why are pox virus not replicated in the nucleus?

It is the largest DNA virus so it cannot enter the nucleus.

A DNA virus that is most commonly latent in trigeminal ganglia



Transmission: secretion, saliva


Significance: temporal lobe encephalitis


Herpes simplex virus-1

A DNA virus latent in sacral ganglia. It can cause herpes genitalis and neonatal herpes.

Herpes simplex virus-2

A DNA virus latent in dorsal root or trigeminal ganglia.

Varicella-Zoster virus (HHV-3)

The most common complication in shingles.

post-herpetic neuralgia

Mononucleosis is caused by what DNA virus?

Epstein-Barr virus (HHV-4)

The use of Amoxicillin in mononucleosis can cause ________.

characteristic maculopapular rash

Epstein-Barr virus can cause __________ which is characterized by fever, hepatosplenomegaly, pharyngitis. It is advised to avoid contact sports.

Mononucleosis

Enumerate the Naked DNA Virus

Papillomavirus


Adenovirus


Parvovirus


Polymavirus

Enumerate the Naked RNA Virus

Calicivirus


Picornavirus


Reovirus


Hepevirus

It has a characteristic of "owl eye" intranuclear inclusions and is latent in mononuclear cells.

Cytomegalovirus

A type of DNA virus that can cause high fevers for several days that can lead to seizures.

Roseola infantum (exanthem subitum) - HHV6&7

It is often seen in HIV/AIDS and transplant patients.

Kaposi sarcoma - HHV-8

It is the largest DNA virus

Poxvirus

T or F



Poxvirus has no envelope.

F.



Poxvirus, Herpevirus, Hepadnavirus has an envelope.



DNA viruses without envelopes are Adenovirus, Papillomavirus, Polymavirus, Parvovirus.

Smallpox was eradicated worldwide by the use of ________.

live-attenuated vaccine

A flesh-colored papule with central umbilication.

Molluscum contagiosum

Its medical importance includes:



Febrile pharyngitis


Conjunctivitis


Mycocarditis

Adenovirus

Its medical importance includes:



HPv-warts (serotypes 1,2,6,11)


Cervical cancer (commonly 16,18)

Papillomavirus

Medical importance of Polymavirus:



_________ - progressive multifocal leukoencephalopathy



_________ - transplant patient, commonly targets the kidney

JC virus


BK virus

Aplastic crises in sickle cell disease, "slapped cheek" rash in children.

B19 virus

DNA virus that is partially DS and circular.

Hepadnavirus

DNA virus with DS and circular structure.

Papillomavirus, Polymavirus

A reovirus that can cause fatal diarrhea in children.

Rotavirus

aka. Colorado tick fever

Coltivirus

A Picornavirus also known as hand, foot, and mouth disease.

Coxsackievirus

The name the 5 medically important Picornavirus.


Poliovirus


Echovirus


Rhinovirus


Coxsackievirus


HAV

PERCH

A Picornavirus known as the "common cold".

Rhinovirus

A calicivirus that is common in older children. It causes viral gastroenteritis and is also known as "Norwalk virus".

Norovirus

What is known as the "Toga CREW"?

Chikungunya virus


Rubella


Eastern and Western equine encephalitis

Enumerate at least 3 medically important Flavivirus

HCV


Yellow fever


Dengue


St. Louie encephalitis


West Nile virus


Zika virus

A Paramyxovirus that causes bronchiolitis in babies.

RSV - Respiratory Syncytial Virus

A Paramyxovirus that causes croup especially in babies.

Parainfluenza

An RNA virus that causes influenza virus.

Orthomyxovirus

An RNA virus that causes rabies.

Rhabdoviruses

An RNA virus that causes Ebola/Marbug hemorrhagic fever that can often be fatal.

Filovirus

An RNA virus that have reverse transcriptase that can cause T-cell leukemia (HLTV) and AIDS.

Retrovirus

An Arenavirus can cause ________ that is spread by rodents.

Lassa fever encephalitis

It is a defective virus that needs presence of HBV to replicate.

HDV

The only DNA hepatitis virus.

HBV - DNA Hepadnavirus

Enumerate the two Hepatitis virus that is transmitted through fecal-oral route.

HAV - RNA Picornavirus


HEV - RNA Hepevirus

It is transmitted primarily by blood (IVDU) and may progress to Cirrhosis or Carcinoma.

HCV - RNA Flavivirus

A hepatitis virus that has a short incubation time that can cause fulminant hepatitis and has a high mortality in pregnant women.

HEV - RNA Hepevirus

A hepatitis virus that has superinfection (HDV after HBV) = short coinfection (HDV with HBV) = long.

HDV - RNA deltavirus

A hepatitis virus that has a carrier state.

HBV - DNA Hepadnavirus


HCV - RNA Flavivirus

A torch infection that manifests as "blueberry muffin" rash.

Toxoplasma gondii


Cytomegalovirus

What is the classic triad experienced when you have Rubella?

eye - cataracts


ear - deafness


heart - congenital heart disease

A torch infection that can cause periventricular calcifications.

Cytomegalovirus

Enumerate the torch infections that can be transmitted through sexual contact.

Cytomegalovirus


HIV


Syphilis

The classic triad experienced in Toxoplasma gondii.

Chorioretinitis


Hydrocephalus


Intracranial calcifications

A torch infection that often results in stillbirth.

Syphilis

A torch infection that manifests as recurrent infection, accompanied with chronic diarrhea.

HIV

A torch infection that can cause Meningoencephalitis and herpetic lesions.

Herpes simplex virus-2

In gram staining, A ______ intensifies the color of the stain.

mordant

Mordant used in gram staining

Iodine

color of gram(+) bacteria in gram staining

blue-violet/blue

color of gram(-) bacteria in gram staining

pinkish-red

It is used to differentiate the stains in gram staining.

decolorizer

A part of gram(-) cells that can cause a disorganized immune response(septic shock).

LPS - lipopolysaccharide

A type of cells that are vulnerable to lysosome and penicillin attack.

gram(+) cells

A type of cell that has no endotoxin, periplasmic space and porin channel.

gram(+) cells

The only spirochete that can be stained on gram staining because of its size.

Borrelia

What is the reason why Treponema and Leptospira cannot be gram-stained?

too thin

A bacteria that cannot be gram-stained because it has high lipid content on its cell wall.

Mycobateria

Treponema and Leptospira can be detected using __________.

Darkfield microscopy

Mycoplasma and Ureaplasma can be detected by ___________.

Serology

A bacteria that lacks classic peptidoglycan because of muramic acid.

Chlamydia

Enumerate the gram(+) circular/cocci bacteria

Staphylococcus


Streptococcus Enterococcus

Enumerate the gram(+) rod/bacilli bacteria

Bacillus


Corynebacterium


Listeria


Clostridium



What is an example of gram(-) circular/cocci bacteria?

Neisseria Moraxella

Enumerate the gram(-) spiral bacteria

Spirochetes


- Treponema


- Borrelia


- Leptospira


Enumerate the gram(+) branching bacteria

Nocardia


Actinomyces

Enumerate the gram(-) pleomorphic bacteria

Chlamydia


Rickettsia



- both are also called obligate intracellular organisms

Bacterial Structures



_________ - motility


_________ - adheres to cell surfaces


_________ - for survival; resist heat, chemicals, and dehydration

Flagellum


Pilus/Fimbriae


Spore

The core of a spore contains _______.

Dipicolinic acid

Spores are killed by autoclaving at what temperature?

121°C for 15 minutes

Cell Envelope Structures



It is the site of oxidative and transport enzymes.

Cytoplasmic membrane

Cell Envelope Structure



A rigid polysaccharide that protects against phagocytosis.

Capsule

Cell Envelope Structure



A loose polysaccharide that mediates adherence to surfaces, especially foreign surfaces.

Slime layer

Cell Envelope Structure



A bet-like structure that gives rigid support against osmotic pressure damage.

Cell wall

Bacterial staining



_______ - acid-fast bacteria


_______ - Cryptococcus neoformans

Ziehl-Nelseen stain


India Ink stain

Bacterial staining



Tannic acid salt tx - __________


Welch method - ___________

Flagella


Capsule

Bacterial staining



Feulgen stain - ________


Malachite green - _________


Periodic acid-schiff stain - _______

Nucleoid


Spore


Glycogen

Media used for isolation of H. influenzae

chocolate agar

It is isolated in eaton agar and it requires cholesterol.

M. pneumoniae

B. pertussis is isolated in ______ and _______.

Bordet-Gengou agar


Regan-Lowe medium

It is isolated using MacConkey agar and the fermentation produces acids causing the colonies to turn pink.

Lactose-fermenting enterics

It is isolated using Eosin-methylene blue agar and have a colonies with green metallic sheen.

E.coli

It is isolated in charcoal yeast extract agar buffered with cysteine and iron.

Brucella, Francisella, Legionella, Pasteurella

A fungi is isolated in ________.

Sabouraud agar

T or F



Are exotoxins located in bacterial chromosome?

F.



Exotoxins are located in a plasmid or bacteriophage while endotoxins are located in bacterial chromosome.

T or F



Exotoxins are sourced from certain species of gram(+) and gram(-) bacteria.

True.



Exotoxins - gram(+) and gram(-)


Endotoxins - gram(-)

A toxin that is destroyed rapidly at 60°C.

Exotoxins

A toxin that has a high adverse effect (ex. botulism).

Exotoxins

A toxin that is stable at 100°C for 1hr.

Endotoxins

Enumerate the typical diseases caused by Exotoxins.

Botulism, diphtheria, cholera, tetanus

Enumerate the typical disease caused by endotoxins.

Meningococcemia, sepsis

What are the two causes of S. aureus?

Inflammatory and Toxin-mediated diseases

Predisposing factor of S. aureus

Vaginal tampons or nasal packing

Treatment for community-acquired infections

Clindamycin

Treatment for hospital-acquired infections

Vancomycin

S. aureus that cause skin infections, organ abscess, pneumonia, acute endocarditis


Inflammatory disease

S. aureus



toxic shock syndrome, scalded skin syndrome, and rapid-onset food poisoning

Toxin-mediated disease

It is used to differentiate Streptococcus and Staphylococcus

Catalase test

An important cause of serious nosocomial and community-acquired infection due to altered penicillin-binding protein

MRSA (methicillin-resistant S. aureus)

A staphylococcus that is Novobiocin sensitive and does not ferment mannitol. It infects prosthetic devices and IV catheters by producing adherent biofilms.

S. epidermidis

A staphylococcus that is Novobiocin resistant and it is the second most cause of uncomplicated UTI in young women (1st - E.coli).

S. saprophyticus

Enumerate the alpha-hemolytic streptococcus

S. pneumoniae


Viridans

Streptococcus pneumoniae commonly causes:



1.


2.


3.


4.

Meningitis


Otitis media


Pneumonia


Sinusitis



MOPS

T or F



Is S. viridans optochin sensitive and bile soluble?

F



S. Viridans - optochin resistant and bile insoluble


S. pneumoniae - optochin sensitive and bile soluble



A streptococcus that is gram(+), alpha-hemolytic, lancet shaped diplococci, encapsulated, IgA protease.

S. pneumoniae

A Viridans group that causes dental caries.

S. mutans and S. mitis

A Viridans group that causes subacute bacterial endocarditis.

S. sanguinis

Where does Viridans group live?

mouth

It is also known as Group A streptococci.

S. pyogenes

It is also known as Group B streptococci.

S. agalactiae

Group A streptococcus can cause:



1.


2.


3.

Pyogenic


Toxigenic


Immunologic

A blanching, sand-paper-like body rash, strawberry tongue, and circumoral pallor in the setting of group A streproccocal pharyngitis.

Scarlet fever

A streptococcus that can give rise to rheumatic fever.

S. pyogenes

A streptococcus that mainly occurs in babies.

S. agalactiae

Enumerate the y-hemolytic Streptococcus.

S. bovis


Enterococci

A type of S. bovis that can cause bacteremia and is associated with colon cancer.

S. gallolyticus (S. bovis biotype 1)

An important cause of nosocomial infection.

VRE (vancomycin-resistant enterococci)

A type of Streptococcus that are normal colonic flora that are penicillin G resistant.

Enterococci

T or F



Streptococci are more resilient than Enterococci.

F.



Enterococci are more resilient as it can grown in 6.5% NaCl and bile lab test.

A spore-forming rod that produces anthrax toxin and has a polypeptide capsule. It is refered to as "medusa head".

Bacillus anthracis

An ulcer with black eschar that uncommonly progresses to bacteremia and death.

Cutaneous anthrax

A potential bioweapon that can cause pulmonary hemorrhage, mediastinitis, and shock. It is also known as woolsorter's disease.

Pulmonary anthrax

It is known as the reheated rice syndrome that can be managed by supportive care (antibiotics are ineffective against toxins).

Bacillus cereus

Enumerate the Bacilli that are spore-forming and aerobic.

Bacillus anthracis


Cutaneous anthrax


Pulmonary anthrax


Bacillus cereus


A bacilli that produces tetanospasmin that blocks release of GABA and glycine. It can cause spastic paralysis.

Clostridium tetani

Predisposing factor of Clostridium botulinum

Canned goods

Symptoms of Botulism

Diplopia


Dysarthria


Dysphagia


Dyspnea

4Ds

Clostridium botulinum can cause botulism in adults by ________ and in babies by _______.

Adults - ingestion of preformed toxins


Babies - ingestion of spores

It produces alpha toxin that can cause gas gangrene.

Clostridium perfringens

Complications associates with Clostridioides difficile.

Toxic megacolon

It can cause pseudomembranous colitis that are often secondary to antibiotic use especially clindamycin or ampicillin.

Clostridioides difficile

Enumerate the Bacilli that are spore-forming and anaerobic

Clostridium tetani


Clostridium botulinum


Clostridium perfringens


Clostridioides difficile

Enumerate Bacilli that are nonspore-forming and aerobic

Listeria monocytogenes


Corynebacterium diptheriae

A bacilli that has a tumbling motility characteristic in a broth and acquired by ingestion of unpasteurized dairy products.

Listeria monocytogenes

Enumarate at least 2 disease associated with Listeria monocytogenes

Amnionitis


Septicemia


Spontaneous abortion


Granulomatosis infantiseptica


Meningitis (immunocompromised)


Self-limited gastroenteritis (healthy individuals)

Treatment for Listeria monocytogenes

Ampicillin

A gram(+) rods occuring in angular arrangements that have symptom that includes pseudomembranous pharyngitis.

Corynebacterium diptheriae

Toxin dissemination of _________ may cause mycocarditis, arrhythmias, and neuropathics.

Corynebacterium diptheriae

Corynebacterium diptheriae are black colonies on ___________.

cystine-tellurite agar

T or F



Nocardia are found in soil while Actinomyces are found in normal oral, reproductive, and GI flora.

T

A type of branching filament that forms yellow sulfur granules.

Actinomyces

T or F



Nocardia is treated with Ampicillin.

F



Nocardia - TMP-SMX


Actinomyces - Penicillin

A branching filament that can mimic TB.

Nocardia

Actinomyces are anaerobic and not acid-fast.

T



Nocardia - aerobe, acid-fast(weak)

Enumerate the branching filaments

Nocardia


Actinomyces

A Neisseria that has NO polysaccharide capsule, maltose acid detection, and vaccine due to antigenic variation of pilus proteins.

Gonococci

T or F



Meningococci is transmitted sexually or perinatally.

F



Gonococci - sexually or perinatally


Meningococci - respiratory, oral secretions

T or F



Gonococci and Meningococci are treated with Ceftriaxone.

T

Enumerate the four Haemophilus influenzae causes

Pneumonia


Otitis Media


Epiglottis


Meningitis



POEM

The most infectious clinical stage of Bordetella pertussis

Catarrhal

Three clinical stages of Bordetella pertussis

Catarrhal


Paroxysmal


Convalescent

A coccobacilli that may be mistaken as viral infection due to lymphocytic infiltrate resulting to immune response and is prevented by Tdap, DTaP vaccines.

Bordetella pertussis

Treatment for Bordetella pertussis

Macrolides and if allergic, TMP-SMX

It is transmitted via ingestion of unpasteurized milk and can cause undulant fever.

Brucella

Treatment for Brucella

Doxycycline + Rifampin or Streptomycin

A commensal opportunist but increasingly associated with resistant hospital-acquired infection.

Acinetobacter baumannii

An S-shaped, gram(-) organism that grows at 42°C and is a major cause of bloody diarrhea.

Campylobacter jejuni

It is the most common cause of bacterial gastroenteritis (ascending flaccid paralysis).

Campylobacter jejuni

It grows in alkaline media that produces profuse rice-water diarrhea and can be transmitted by ingestion of contaminated water or uncooked food like raw shellfish.

Vibrio cholerae

Treatment for Vibrio cholerae

Oral hydration solution

Enumarate the Curved rods

Campylobacter jejuni


Vibrio cholerae


Helicobacter pylori

A gram(-) rod that is triple (+): catalase, oxidase and urease that can cause gastritis and peptic ulcers

Helicobacter pylori

Treatment for H. pylori

Triple therapy



Amoxicillin + Clarithromycin + Proton Pump Inhibitor

E coli virulence factors



Fimbriae - __________


Capsule - ___________


LPS endotoxin - ________

1. cystitis and pyelonephritis


2. pneumonia, neonatal meningitis


3. septic shock

An E.coli that has a similar manifestation with Shigella. The microbes invades intestinal mucosa and causes inflammation and necrosis.

Enteroinvasive E. coli

An E. coli that produces heat-labile and heat-stable enterotoxins. It does not cause inflammation or invasion.

Enterotoxigenic E. coli

An E. coli that usually causes diarrhea in children as it adheres to apical surfaces flattens villi, thus, preventing absorption.

Enteropathogenic E. coli

The most common serotype in US that is transmitted via undercooked meat, raw leafy vegetables.

O157:H7

Enumarate the triad of hemolytic-uremic syndrome

Anemia, thrombocytopenia, and acute kidney failure

An E.coli that does not ferment sorbitol.


Enterohemorrhagic E. coli

ABCDE's of Klebsiella

Aspiration pneumonia


aBscess in lung and liver


Currant jelly sputum


Diabetes


EtOH abuse

A dark red currant jelly sputum that causes lobar pneumonia in alcoholics and diabetes and is associated with evolution of mutlidrug resistance.

Klebsiella

Enumerate the lactose fermenter Bacilli

E. coli


Klebsiella

A nom lactose fermenting bacilli that is usually found in water and has a grape fruit-like odor.

P. aeruginosa

It is rapidly progressive necrotic cutaneous lesion caused by P. bacteremia, typically seen in immunocompromised patients.

Ecthyma gangrenosum

Treatment for P. aeruginosa

Carbapenems


Aminoglycosides


Monobactams


Polymyxins


Fluoroquinolones


thIRd and fourth gen cephalosporins


Extended-spectrum penicillins

CAMPFIRE

Enumarate the infections/diseases associated with Pseudomonas

Pneumonia


Sepsis


Ecthyma gangrenosum


UTI


Diabetes


Osteomyelitis


Mucoid polysaccharide capsule


Otitis externa (swimmer's ear)


Nosocomal infections


Addicts


Skin infections (hot tub folliculitis)

T or F



The reservoirs of Salmonella typhi and Shigella are humans.

T.



Only Salmonella spp (except typhi) have human and animal reservoir

Y or N



Does Shigella produce H2S?

N



Salmonella typhi and Salmonella spp (except typhi) produces H2S

Salmonella vs Shigella



It does not have a flagellum.

Shigella



Salmonella can swim 👹

Salmon vs Shigella



In terms of injection dose, it has a very small inoculum required and resistant to gastric acid

Shigella

Salmonella vs Shigella



It has a prolonged effect of antibiotics on fecal excretion.

Salmonella

Salmonella vs Shigella



It does not have a vaccine.

Salmonella spp except typhi amd Shigella



S. typhi requires oral vaccines

Unique properties of Salmonella and Shigella



It causes typhoid fever that can be treated with Ceftriaxone. It is also a carrier state with gallbladder colonization.

Salmonella typhi

Unique properties of Salmonella and Shigella



It can cause gastroenteritis.


Salmonella spp except typhi

4F's of Shigella

Fingers


Flies


Food


Feces

A disease caused by Borrelia burgdorferi which is transmitted by Ixodes deer tick.

Lyme disease

Treatment for lyme disease

Doxycycline

Manifestation of Lyme disease

Facial nerve palsy


Arthritis


Cardiac block


Erythema migrans

FACE

Erythema migrans is a lyme disease manifestation at what stage?

Stage 1

Facial nerve palsy is a lyme disease manifestation at what stage

Stage 2

Encephalopathy is a lyme disease manifestation at what stage?

Stage 3

What is the natural reservoir of Borrelia burgdorferi?

Mouse

A spirochete with hook-shaped ends found in water contaminated with animal urine.

Leptospira interrogans

A disease caused by Leptospira interrogans that have flu-like symptoms, photophobia with conjunctival suffusion, common in surfers and tropics.

Leptospirosis

A disease caused by Leptospira interrogans that is a severe form with jaundice and azotemia from lover and kidney dysfunction, fever, hemorrhage, and anemia.

Weil disease

Causative agent of syphilis

Treponema pallidum

Treatment for syphilis

Penicillin G

A type of syphilis with localized disease presenting with painless chancre.

Primary

A type of syphilis that is a disseminated disease with constitutional symptoms, maculopapular rash.

Secondary

A type of syphilis that is often called prostitute's pupil as it accommodates but never reacts. A gummas that can cause neurosyphilis and stroke without hypertension.

Tertiary

A syphilis that presents with facial abnormalities.

Congenital

Causative agent and Transmission/Source of Anaplasmosis

CA - Anaplasma spp


T/S - Ixodes tick

Causative agent and Transmission/Source of Cat scratch disease

CA - Bartonella spp


T/S - Cat scratch

Causative agent and Transmission/Source of Lyme disease

CA - Borrelia Burgdorferi


T/S - Ixodes tick

Causative agent and Transmission/Source of Relapsing fever

CA - Borrelia recurrentis


T/S - Louse

Causative agent and Transmission/Source of Brucellosis/Undulant fever

CA - Brucella spp


T/S - Unpasteurized dairy

Causative agent and Transmission/Source of Blood diarrhea

CA - Campylobacter


T/S - feces from infected pets/animals; contaminated food/hands

Causative agent and Transmission/Source of Psittacosis

CA - Chlamydophila psittaci


T/S - Parrots

Causative agent and Transmission/Source of Q fever

CA - Coxiella burnetii


T/S - Aerosols of cattle/sheep amniotic fluid

Causative agent and Transmission/Source of Ehrlichiosis

CA - Ehrlichia chaffeensis


T/S - Ambylomma (Lobe star tick)

Causative agent and Transmission/Source of Tularemia

CA - Francisella tularensis


T/S - tick, rabbit, deer flies

Causative agent and Transmission/Source of Leptospirosis

CA - Leptospira spp


T/S - animal urine in water

Causative agent and Transmission/Source of Leprosy

CA - Mycobacterium leprae


T/S - humans with lepromatous leprosy, armadillo

Causative agent and Transmission/Source of Cellulitis and Osteomyelitis

CA - Pasteurella multocida


T/S - animal bites, cats, dogs

Causative agent and Transmission/Source of Epidemic typhus

CA - Rickettsia prowazekii


T/S - human to human via human body louse

Causative agent and Transmission/Source of Rocky mountain spotted fever

CA - Rickettsia rickettsii


T/S - dog ticks (dermacentor)

Causative agent and Transmission/Source of Endemic typhus

CA - Rickettsii typhi


T/S - fleas

Causative agent and Transmission/Source of Diarrhea, Vomiting, Fever, Abdominal cramps

CA - Salmonella except typhi


T/S - reptiles and poultry

Causative agent and Transmission/Source of Plague

CA - Yersinia pestis


T/S - Fleas

A screening for nontreponemal syphilis

RPR


VDRL

A confirmatory treponemal test for syphilis

FTA-ABS


TPPA

A declaration that states that health is a human right and it should be made available for everyone.

Declaration pf Alma Mata (1978)

A level f disease that even one case can cause a concern in the specific area. An example is Huntington's disease in the Philippines.

Sporadic

A level of disease thay refers to persistent, high levels of disease occurrence.

Hyperendemic

Three core functions of Public Health

Assessment


Policy Development


Assurance

A level of disease that refers to the constant presence and/or usual prevalence of a disease in a population within a geographic area.

Endemic

A level of disease that refers to an increase, often sudden, in the number of cases of a disease above what is expected in an area.

Epidemic

A level of disease that carries the same definition of epidemic but is often used for a more limited geographic area.

Outbreak

A level of disease that refers to an aggregation of cases grouped in place and time that are suspected to be greater than the number expected.

Cluster

A level of disease that refers to an epidemic that has spread over several countries.

Pandemic

T or F



An epidemiologic triad does not work on non-infectious disease.

T



Common causes and Casual pies works for non-infectious disease.

A type of pie that is proposed by Rothman in 1976 that assigns the individual factors that causes a disease in a pie, and after the pie is completed — the disease is predicted.

Rothman Casual Pie

T or F



A disease and other health events occurs randomly in a population.

F

It is the study of the distribution and determinants of health-related state in a specified population, and the application of this study to control health problems.

Epidemiology

It is a result of medical condition that directly affects the length or quality of a person's life.

Health outcome

It is a factor that contributes to the generation of a trait.

Determinants