[Microbiology]: Prion And Fungal Diseases

Front 1

Transmissible spongiform encephalopathies are aka ____

Back 1

Prion Diseases

Front 2

What is the etiologic agent of Transmissible spongiform encephalopathies?

Back 2

..controversial, thought to be prions.

Front 3

What is a prion

Back 3

Replicating protein without any know associated nucleic acids

Front 4

Can prion protiens be affected by
a.) X-rays B.) UV rays C.)10% formalin D.) Sodium hypochlorite E.)AOT F.)NOT

Back 4

D. Only sodium hypochlorite (Bleach)

Front 5

In the white matter of a pt's cerebrum protien is aggregating resembling fiber-like tangles. This is a sx of?

Back 5

A prion disease

Front 6

Tangles resembling the amyloid plaques associated with alzheimers is a sx associated with __

Back 6

Prion Diseases

Front 7

Dementia, memory loss, behavior abnormalities and motor ataxias are sx of ___

Back 7

Prion Diseases

Front 8

Death occurs within _______ following onset of SX of a prion disease

Back 8

months to a year

Front 9

Scrapie

Back 9

The first prion disease discovered, occurring in sheep.

Front 10

BSE- what does it stand for and it's aka term

Back 10

Bovine Spongioform Encephalopathy - aka "Mad Cow Disease"

Front 11

BSE occurs in which animal?

Back 11

Cow

Front 12

BSE was first discovered in ___ (where) in ____ (when)

Back 12

England, 1986

Front 13

How did cattle obtain BSE?

Back 13

Eating sheep brains & viscera

Front 14

In what year was it discovered that humans could aquire BSE from eating cattle affected by it?

Back 14

1996

Front 15

Kuru

Back 15

First prion disease discovered in humans

Front 16

Which group of people were the first to aquire Kuru?

Back 16

Remote tribe of aborigines in New Guinea

Front 17

How did the New Guineans acquire Kuru?

Back 17

By eating the brain of dead relatives

Front 18

CJD - what is it?

Back 18

Creutzfeld-Jakob Disease- a rare prion disease occurring in humans

Front 19

Atypical CJD was first aquired by

Back 19

Eating diseased beef in england

Front 20

In the 1970's, CJD was aquired by

Back 20

using cadaverous somatotopin (hST) in the U.S.

Front 21

GSS

Back 21

Gerstmann-Straussler-Scheinker-Syndrome - a rare prion disease occurring in humans

Front 22

CWD stands for

Back 22

Chronic Wasting Disease

Front 23

CWD is a disease affecting

Back 23

deer and elk, captive and free-range

Front 24

How can deer hunters prevent getting CWD?

Back 24

Wearing gloves when field dressing carcasses and not eat obviously ill animals

Front 25

What diagnostic tests are available to detect prion diseases?

Back 25

None- usually confirmed by sx and autopsy

Front 26

Dermatophytosis

Back 26

mycosis infections of the skin due to Parasitic fungi

Front 27

Tinea

Back 27

Ringworm, fungal

Front 28

Tinea barbae

Back 28

Ringworm of the beard, fungal

Front 29

Tinea capitis

Back 29

Ringworm of the head, fungal

Front 30

Tinea corporis

Back 30

Ringworm on smooth or bare parts of skin, fungal

Front 31

Tinea cruris

Back 31

Jock itch, ring worm of the crotch, fungal

Front 32

tinia pedis

Back 32

athlete's foot, ringworm of the foot, fungal

Front 33

tinia unguim

Back 33

ringworm in the nails, fungal

Front 34

Coccidioidomycosis is what type of fungal mycoses?

Back 34

Systemic mycoses

Front 35

Coccidioidomycosis is also known as

Back 35

Valley fever

Front 36

the etiologic agent causing Coccidioidomycosis is

Back 36

Coccidiodes immitis

Front 37

Where is Coccidioidomycosis most common?

Back 37

semi-arid regions like San Joaquin Valley, CA

Front 38

What are the symptoms of Coccidioidomycosis

Back 38

Mild URT

Front 39

How is Coccidioidomycosis treated?

Back 39

Usually self-limiting, if not: Amphotericin B

Front 40

MOT for Coccidioidomycosis

Back 40

spore inhalation

Front 41

Coccidioidomycosis can be fatal when spread to

Back 41

the liver, kidneys or meninges

Front 42

Cryptococcosis is what type of disease?

Back 42

Systemic mycoses

Front 43

The etiologic agent causing cryptococcosis

Back 43

Cryptococcus neoformans

Front 44

Cryptococcus neoformans is a yeast associated with _

Back 44

aged, dried bird feces, esp. pigeons

Front 45

MOT of cryptococcosis

Back 45

Spore inhalation

Front 46

SX of Cryptococcosis

Back 46

Mild lung infection,

Front 47

if cryprococcosis spreads from the lungs to the CNS it is then called

Back 47

Cryptococcus meningitis

Front 48

Opportunistic systemic mycoses

Back 48

Fungi which occur naturally in the body become pathogenic in the immune suppressed or in increased number

Front 49

Tx for cryptococcosis

Back 49

Anohotericin B or Fluoricystosine

Front 50

Histoplasmosis

Back 50

A systemic mycoses aka Cave Sickness

Front 51

EA for histoplasmosis

Back 51

Histoplasma capulatum

Front 52

MOT of histoplasmosis

Back 52

spore inhalation

Front 53

RES of histoplasmosis

Back 53

bird and bat guano

Front 54

What animal does not get sick from histoplasmosis?

Back 54

birds

Front 55

Why don't birds get sick with histoplasmosis?

Back 55

Birds have higher body temp

Front 56

Histoplasmosis is an endemic in

Back 56

Miss, Ohio, rio Grande valley

Front 57

What are the sn/sx of histoplasmosis?

Back 57

lung infection similar to TB, rarely spreads to bone marrow

Front 58

EA for candidiasis

Back 58

Candidia albicans

Front 59

What bacteria keeps Candidia albicans in check and how?

Back 59

Lactobacillus sp, lowers pH

Front 60

Candidia albicans is a...
obligate/facultative/aerobe/anaerobe

Back 60

strict anaerobe

Front 61

What is thrush?

Back 61

oral form of candidiasis

Front 62

How is thrush obtained

Back 62

in babies who's mother has vaginal infection

Front 63

Candidiasis in the nails is usually due to

Back 63

being submerged in water too much

Front 64

Candidia albicans can cause ___ in babies who aren't changed often enough

Back 64

Diaper rash

Front 65

Topical treatments for candidiasis

Back 65

Nystatin, myconazole, gentian violet

Front 66

TX of systemic candidiasis

Back 66

Amphotericin B

Front 67

EA of aspergillosis

Back 67

Aspergillus fumigatus

Front 68

MOT of aspergillosis

Back 68

spore inhalation

Front 69

Sx of aspergillosis

Back 69

allergic reaction causing asthma

Front 70

in cases of aspergillosis, aspergillomas in the bronchi or lungs can result in

Back 70

Bronchopneumonia

Front 71

TX of aspergillosis

Back 71

amphotericin B or fluorocytosine

Front 72

Aflatoxin poisoning EA

Back 72

Aspergillus flavus

Front 73

Aflatoxin poisoning's EA occurs in

Back 73

soil

Front 74

Aflatoxin poisoning MOT

Back 74

ingestion of foods with toxin

Front 75

Aflatoxin poisoning sx

Back 75

Cancer

Front 76

TX of aflatoxin poisoning

Back 76

none (prevent)

Front 77

Mushroom poisoning EA

Back 77

Amanita phallides .aka death cap mushroom

Front 78

Death cap mushrooms produce which two toxins

Back 78

Phalloidin and a-amatoxin

Front 79

In cases of mushroom poisoning, Phalloidin ___ resulting in _____

Back 79

lyses hepatocytes resulting in hepatic necrosis

Front 80

In cases of mushroom poisoning, a-amatoxin causes

Back 80

severe GIT distress

Front 81

Hallucinogenic poisoning EA

Back 81

Psilocybe

Front 82

Hallucinogenic poisoning is caused by an alkaloid in the mushroom called

Back 82

psilocybin

Front 83

Sacred mushrooms used in incan religious ceromonies cause

Back 83

hallucinogenic poisoning

Front 84

teonanacatl =

Back 84

flesh of the gods, what the incans called the hallucinogenic mushrooms

Front 85

peyote=

Back 85

hallucinogenic cactus

Front 86

Edible mushroom species

Back 86

Agaricus bisporus

Front 87

Agaricus bisporus aka

Back 87

common white button mushrooms

Front 88

mature agaricus bisporus aka

Back 88

portabella

Front 89

Lophorphora williamsii

Back 89

Peyote - hallucinogenic cactus