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54 Cards in this Set
- Front
- Back
Staphylococcus epidermidis is a part of the normal flora of which areas of the human body?
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Skin
Nose Urogenital Tract |
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Staphylococcus aureus is a part of the normal flora of which areas of the human body?
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Skin
Nose |
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Candida sp. is a part of the normal flora of which area(s) of the human body?
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Skin
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Streptococcus mutans is a part of the normal flora of which area(s) of the human body?
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Mouth
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Streptococcus pyogenes is a part of the normal flora of which area(s) of the human body?
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Pharynx
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Streptococcus pneumoniae is a part of the normal flora of which area(s) of the human body?
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Pharynx
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Lactobacilli is a part of the normal flora of which area(s) of the human body?
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Intestines
Urogenital tract |
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Bacteriodes are a part of the normal flora of which area(s) of the human body?
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Intestines
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Enterococcus faecalis is a part of the normal flora of which area(s) of the human body?
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Intestines
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Clostridium perfringens is a part of the normal flora of which area(s) of the human body?
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Intestines
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Enterobacteria (E. coli) is a part of the normal flora of which area(s) of the human body?
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Intestines
Urogenital tract |
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Streptococcus faecalis is a part of the normal flora of which area(s) of the human body?
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Urogenital tract
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What are 2 factors that enhance colonization of bacteria?
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Adhesions
Biofilm |
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What are 2 factors that resist host defenses?
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Anti-phagocytic capsules
Proteases that degrade antibodies and other factors |
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What is a factor that enhances invasiveness?
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Enzymes that break down connective tissue
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What are some major sites of entry for microbial diseases?
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Mouth
Resp. tract Skin/mucous membranes Urogenital tract Conjunctiva |
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What are some microbial adaptations to assist entry of microbes?
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* Survival for long periods outside of hose
* Colonization of skin * Attachment structures * Survival in stomach acid, proteolytic enzymes, bile * Use of vectors |
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What are some ways that microbes try to avoid host defenses?
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*Numerous mechanisms
*Hide within cells *Change antigens *Try to appear like host |
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How can microbes spread through body? (hint: 2 ways)
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Local spread
Systemic spread |
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What are 2 ways microbes utilize local spread to go throughout the body?
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*Degradative enzymes
*Fusion inducing proteins |
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What are some mechanisms microbes use to systemically spread thru the body?
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*Lymphatics
*Blood *Nerves |
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What stage of the infectious process is characterized by no symptoms but the organism is replicating a spreading?
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Incubation period
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This part of the infectious process is due to microbe and host response.
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Illness
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When can shedding occur?
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Before, during, and after the clinical illness
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What are the causes of tissue damage?
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1. Microbe itself (Cell lysis due to microbe replication and microbial toxins)
2. Host inflammatory responses |
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Infection is completely cleared from the body
(CHOOSE ONE:Acute, Chronic, or Latent?) |
Acute Infection
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Constant shedding of the microbe
(CHOOSE ONE:Acute, Chronic, or Latent?) |
Chronic Infection
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DNA of virus hiding in cells and can come out at any time
(CHOOSE ONE:Acute, Chronic, or Latent?) |
Latent Infection
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What are some host factors that influence the outcome of the infection?
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Age
Sex Nutrition Genetics Immune Status |
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What are some microbial factors that influence the outcome of the infection?
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Virulence factors
Anti-microbial resistance Antigenic variants Emerging pathogen Infectious dose |
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What are the 2 groups of bacteria?
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Gram positive
Gram negative |
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What are the 4 categories of protozoa?
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Amoeba
Ciliate Flagellate Sporozoite |
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What 2 shapes do most bacteria assume?
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1. Cocci (spheres)
2. Bacilli (rods) |
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What is meant by endogenous source of infection?
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Normal flora
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What are 3 exogenous sources of infection?
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1. person to person
2. animal to person 3. environment to person |
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Number of new cases of a condition, symptom, death, or injury that arise during a specific period of time
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Incidence
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Number of cases in a given population at a given point or period of time
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Prevalence
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This type of diagnosis detects the presence of anti-pathogen antibodies in patient's serum
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Serologic diagnosis
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In bacteria, the extrachromosomal DNA that code for proteins that give the bacteria a selective advantage
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Plasmids
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70s....Prokaryote or eukaryote?
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Prokaryote
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What are the minimum requirements for bacterial growth?
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Carbon
Nitrogen Energy source Water Certain Ions (Iron) |
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Grow in absence of oxygen and use fermentation pathways
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Anaerobes
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Carries out aerobic respiration and can switch to fermentation in absence of O2
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Facultative anaerobe
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Requires low level of oxygen
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Microaerophilic
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Carries out aerobic respiration
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Obligate aerobe
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What is the most common form of energy for bacterial metabolism?
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ATP
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These processes get energy from energy-containing molecules (glucose and store it as ATP.
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Catabolic processes
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Energy from ATP is used in _____ activities
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anabolic
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Through what process is glucose converted to pyruvate?
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Glycolysis
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What are 3 pathways TO energy formation FROM pyruvate?
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1. Fermentation
2. Aerobic respiration 3. Anaerobic respiration |
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This pathway of pyruvate to energy is carried out by facultative anaerobes during anaerobic conditions
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Fermentation
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This pathway of pyruvate to energy involves TCA cycle and oxidative phosphorylation
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Aerobic Respiration
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This pathway of pyruvate to energy gives the highest yield of ATP
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Aerobic Respiration
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In aerobic respiration, what is the final electron acceptor?
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Oxygen
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